Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases N.A.
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions Transmemebrane
Localizations N.A.
BulkPerturb-seq

Description

Ensembl ID ENSG00000147231 Gene ID 55086 Accession 25486
Symbol RADX Alias CXorf57 Full Name RPA1 related single stranded DNA binding protein, X-linked
Status Confidence Length 67510 bases Strand Plus strand
Position X : 106611930 - 106679439 RNA binding domain N.A.
Summary Enables single-stranded DNA binding activity. Involved in negative regulation of double-strand break repair via homologous recombination. Located in nuclear speck and replication fork. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
RADX-202 ENST00000372548 3852 855aa ENSP00000361628
RADX-204 ENST00000461251 2299 567aa ENSP00000432238
RADX-203 ENST00000421550 2880 566aa ENSP00000405866
RADX-205 ENST00000478395 425 No protein -
RADX-206 ENST00000497124 682 No protein -
RADX-201 ENST00000372544 3607 758aa ENSP00000361623

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003697enables single-stranded DNA binding2IBA,IDAHomo_sapiens(9606)Function
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005657is_active_in replication fork2IBA,IDAHomo_sapiens(9606)Component
GO:0006282involved_in regulation of DNA repair1IBAHomo_sapiens(9606)Process
GO:0016607located_in nuclear speck1IDAHomo_sapiens(9606)Component
GO:2000042involved_in negative regulation of double-strand break repair via homologous recombination1IDAHomo_sapiens(9606)Process

Expression