RBPWorld - a comprehensive database of RNA Binding Proteins

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Functions and Diseases

RBP Type	Canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	E3 ligase
Localizations	N.A.
BulkPerturb-seq

Description

Ensembl ID	ENSG00000146833	Gene ID	89122	Accession	16275
Symbol	TRIM4	Alias	RNF87	Full Name	tripartite motif containing 4
Status	Confidence	Length	42574 bases	Strand	Minus strand
Position	7 : 99876958 - 99919531	RNA binding domain	SPRY
Summary	The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Its function has not been identified. Alternatively spliced transcript variants that encode different isoforms have been described.[provided by RefSeq, Jul 2010]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000275736	SPRY	PF00622	5.6e-07	1
ENSP00000348216	SPRY	PF00622	6.2e-07	1

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
TRIM4-204	ENST00000447480	639	202aa	ENSP00000396229
TRIM4-203	ENST00000355947	3383	500aa	ENSP00000348216
TRIM4-201	ENST00000349062	3314	474aa	ENSP00000275736
TRIM4-202	ENST00000354241	1942	294aa	ENSP00000346186
TRIM4-205	ENST00000496896	601	No protein	-

Gene Model

Click here to download ENSG00000146833's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID
7638	Glomerular Filtration Rate	4.4458022995908E-5	17903292
7687	Glomerular Filtration Rate	6.14948630972556E-5	17903292
7824	Creatinine	5.53041871555646E-5	17903292
7869	Creatinine	7.84783516712504E-5	17903292
53215	Dehydroepiandrosterone	3.6980000E-005	-
88403	Hormones	2E-11	21533175
96766	Metabolism	9E-40	21886157

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000146833's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0004842	enables ubiquitin-protein transferase activity	1	EXP	Homo_sapiens(9606)	Function
GO:0005737	is_active_in cytoplasm	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0005829	is_active_in cytosol	3	IBA,IDA,TAS	Homo_sapiens(9606)	Component
GO:0005886	located_in plasma membrane	1	IDA	Homo_sapiens(9606)	Component
GO:0008270	enables zinc ion binding	1	IEA	Homo_sapiens(9606)	Function
GO:0010468	involved_in regulation of gene expression	1	IBA	Homo_sapiens(9606)	Process
GO:0016567	involved_in protein ubiquitination	2	IBA,IEA	Homo_sapiens(9606)	Process
GO:0042802	enables identical protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0045087	involved_in innate immune response	1	TAS	Homo_sapiens(9606)	Process
GO:0061630	enables ubiquitin protein ligase activity	1	IBA	Homo_sapiens(9606)	Function

Expression