Functions and Diseases

RBP Type Canonical_RBPs
Diseases N.A.
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions E3 ligase
Localizations N.A.
BulkPerturb-seq

Description

Ensembl ID ENSG00000146755 Gene ID 135892 Accession 19017
Symbol TRIM50 Alias TRIM50A Full Name tripartite motif containing 50
Status Confidence Length 15547 bases Strand Minus strand
Position 7 : 73312536 - 73328082 RNA binding domain SPRY
Summary Enables identical protein binding activity. Predicted to be involved in protein ubiquitination. Predicted to act upstream of or within regulation of establishment of protein localization. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000327994 SPRY PF00622 4.8e-08 1
ENSP00000413875 SPRY PF00622 4.8e-08 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
TRIM50-201 ENST00000333149 2050 487aa ENSP00000327994
TRIM50-202 ENST00000453152 1599 487aa ENSP00000413875
TRIM50-203 ENST00000488217 548 No protein -
TRIM50-204 ENST00000493498 555 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005737is_active_in cytoplasm1IBAHomo_sapiens(9606)Component
GO:0005829located_in cytosol1IDAHomo_sapiens(9606)Component
GO:0008270enables zinc ion binding1IEAHomo_sapiens(9606)Function
GO:0016567involved_in protein ubiquitination1IBAHomo_sapiens(9606)Process
GO:0042802enables identical protein binding1IPIHomo_sapiens(9606)Function
GO:0061630enables ubiquitin protein ligase activity1IBAHomo_sapiens(9606)Function

Expression