RBPWorld - a comprehensive database of RNA Binding Proteins

Welcome to

RBP World!

Functions and Diseases

RBP Type	Canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	E3 ligase
Localizations	N.A.
BulkPerturb-seq

Description

Ensembl ID	ENSG00000146054	Gene ID	81786	Accession	16278
Symbol	TRIM7	Alias	GNIP;RNF90	Full Name	tripartite motif containing 7
Status	Confidence	Length	11370 bases	Strand	Minus strand
Position	5 : 181193924 - 181205293	RNA binding domain	SPRY
Summary	The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1, a B-box type 2, and a coiled-coil region. The protein localizes to both the nucleus and the cytoplasm, and may represent a participant in the initiation of glycogen synthesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000376991	SPRY	PF00622	7.8e-14	1
ENSP00000391458	SPRY	PF00622	7.8e-14	1
ENSP00000376994	SPRY	PF00622	9.2e-14	1
ENSP00000274773	SPRY	PF00622	1.8e-13	1

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
TRIM7-201	ENST00000274773	2864	511aa	ENSP00000274773
TRIM7-203	ENST00000393315	2851	303aa	ENSP00000376991
TRIM7-206	ENST00000504241	4357	No protein	-
TRIM7-204	ENST00000393319	2320	329aa	ENSP00000376994
TRIM7-205	ENST00000422067	1954	303aa	ENSP00000391458
TRIM7-207	ENST00000509199	599	No protein	-
TRIM7-202	ENST00000334421	1228	221aa	ENSP00000334666

Gene Model

Click here to download ENSG00000146054's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID
47027	Platelet Function Tests	5.3119000E-005	-

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000146054's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	located_in nucleus	1	IDA	Homo_sapiens(9606)	Component
GO:0005737	is_active_in cytoplasm	3	IBA,IDA	Homo_sapiens(9606)	Component
GO:0005794	located_in Golgi apparatus	1	IEA	Homo_sapiens(9606)	Component
GO:0008270	enables zinc ion binding	1	IEA	Homo_sapiens(9606)	Function
GO:0016567	involved_in protein ubiquitination	2	IBA,IEA	Homo_sapiens(9606)	Process
GO:0061630	enables ubiquitin protein ligase activity	2	IBA,IDA	Homo_sapiens(9606)	Function
GO:0140374	involved_in antiviral innate immune response	1	IDA	Homo_sapiens(9606)	Process

Expression