RBP Type	Non-canonical_RBPs
Diseases	Disease
Drug	Drug
Main interacting RNAs	N.A.
Moonlighting functions	Metabolic enzyme
Localizations	N.A.
BulkPerturb-seq

Ensembl ID	ENSG00000145494	Gene ID	4726	Accession	7713
Symbol	NDUFS6	Alias	MC1DN9;CI-13kA;CI13KDA;CI-13kD-A	Full Name	NADH:ubiquinone oxidoreductase subunit S6
Status	Confidence	Length	14642 bases	Strand	Plus strand
Position	5 : 1801407 - 1816048	RNA binding domain	N.A.
Summary	This gene encodes a subunit of the NADH:ubiquinone oxidoreductase (complex I), which is the first enzyme complex in the electron transport chain of mitochondria. This complex functions in the transfer of electrons from NADH to the respiratory chain. The subunit encoded by this gene is one of seven subunits in the iron-sulfur protein fraction. Mutations in this gene cause mitochondrial complex I deficiency, a disease that causes a wide variety of clinical disorders, including neonatal disease and adult-onset neurodegenerative disorders.[provided by RefSeq, Oct 2009]

Protein	Domain	Pfam ID	E-value	Domain number

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
NDUFS6-201	ENST00000274137	518	124aa	ENSP00000274137
NDUFS6-202	ENST00000469176	550	172aa	ENSP00000422557
NDUFS6-203	ENST00000510329	260	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
20111	Uric Acid	5.877e-005	-
20113	Uric Acid	5.877e-005	-

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0005743	located_in mitochondrial inner membrane	1	TAS	Homo_sapiens(9606)	Component
GO:0005747	part_of mitochondrial respiratory chain complex I	4	IBA,IDA,IPI,NAS	Homo_sapiens(9606)	Component
GO:0006120	involved_in mitochondrial electron transport, NADH to ubiquinone	2	IBA,NAS	Homo_sapiens(9606)	Process
GO:0008137	enables NADH dehydrogenase (ubiquinone) activity	1	NAS	Homo_sapiens(9606)	Function
GO:0009055	enables electron transfer activity	1	NAS	Homo_sapiens(9606)	Function
GO:0009060	involved_in aerobic respiration	1	NAS	Homo_sapiens(9606)	Process
GO:0042776	involved_in proton motive force-driven mitochondrial ATP synthesis	1	NAS	Homo_sapiens(9606)	Process