RBP Type	Non-canonical_RBPs
Diseases	SARS-COV-2
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	N.A.
Localizations	Stress granucle
BulkPerturb-seq

Ensembl ID	ENSG00000144848	Gene ID	64422	Accession	20962
Symbol	ATG3	Alias	APG3;APG3L;hApg3;PC3-96;APG3-LIKE	Full Name	autophagy related 3
Status	Confidence	Length	29537 bases	Strand	Minus strand
Position	3 : 112532510 - 112562046	RNA binding domain	N.A.
Summary	This gene encodes a ubiquitin-like-conjugating enzyme and is a component of ubiquitination-like systems involved in autophagy, the process of degradation, turnover and recycling of cytoplasmic constituents in eukaryotic cells. This protein is known to play a role in regulation of autophagy during cell death. A pseudogene of this gene is located on chromosome 20. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]

Protein	Domain	Pfam ID	E-value	Domain number

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
ATG3-201	ENST00000283290	1568	314aa	ENSP00000283290
ATG3-202	ENST00000402314	3010	311aa	ENSP00000385943
ATG3-207	ENST00000494571	2758	No protein	-
ATG3-208	ENST00000495756	1455	No protein	-
ATG3-204	ENST00000467275	559	No protein	-
ATG3-209	ENST00000496423	737	74aa	ENSP00000420259
ATG3-206	ENST00000492886	639	83aa	ENSP00000420378
ATG3-203	ENST00000465980	560	No protein	-
ATG3-205	ENST00000488910	681	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
93207	Asthma	2E-6	23829686

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000045	involved_in autophagosome assembly	2	IBA,ISS	Homo_sapiens(9606)	Process
GO:0000407	is_active_in phagophore assembly site	1	IBA	Homo_sapiens(9606)	Component
GO:0000422	involved_in autophagy of mitochondrion	1	IBA	Homo_sapiens(9606)	Process
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005737	is_active_in cytoplasm	1	IDA	Homo_sapiens(9606)	Component
GO:0005829	is_active_in cytosol	3	IBA,IDA,TAS	Homo_sapiens(9606)	Component
GO:0006612	involved_in protein targeting to membrane	1	ISS	Homo_sapiens(9606)	Process
GO:0016567	involved_in protein ubiquitination	1	IDA	Homo_sapiens(9606)	Process
GO:0019776	enables Atg8-family ligase activity	2	IBA,ISS	Homo_sapiens(9606)	Function
GO:0019777	enables Atg12 transferase activity	1	ISS	Homo_sapiens(9606)	Function
GO:0019787	enables ubiquitin-like protein transferase activity	1	IDA	Homo_sapiens(9606)	Function
GO:0019899	enables enzyme binding	1	IPI	Homo_sapiens(9606)	Function
GO:0043653	involved_in mitochondrial fragmentation involved in apoptotic process	1	ISS	Homo_sapiens(9606)	Process
GO:0044804	involved_in nucleophagy	1	IBA	Homo_sapiens(9606)	Process
GO:0050765	involved_in negative regulation of phagocytosis	1	IEA	Homo_sapiens(9606)	Process
GO:1902017	involved_in regulation of cilium assembly	1	ISS	Homo_sapiens(9606)	Process