RBP Type	Canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	E3 ligaseTF
Localizations	N.A.
BulkPerturb-seq

Ensembl ID	ENSG00000144747	Gene ID	7110	Accession	11870
Symbol	TMF1	Alias	TMF;ARA160	Full Name	TATA element modulatory factor 1
Status	Confidence	Length	32513 bases	Strand	Minus strand
Position	3 : 69019827 - 69052339	RNA binding domain	TMF_TATA_bd , TMF_DNA_bd
Summary	Enables androgen receptor binding activity and nuclear receptor coactivator activity. Involved in androgen receptor signaling pathway and positive regulation of transcription by RNA polymerase II. Located in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2022]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000419330	TMF_DNA_bd	PF12329	3.2e-21	1
ENSP00000381567	TMF_DNA_bd	PF12329	5e-21	1
ENSP00000381567	TMF_TATA_bd	PF12325	3.5e-31	2
ENSP00000494067	TMF_DNA_bd	PF12329	5e-21	1
ENSP00000494067	TMF_TATA_bd	PF12325	3.5e-31	2
ENSP00000496378	TMF_DNA_bd	PF12329	1.1e-19	1
ENSP00000496378	TMF_TATA_bd	PF12325	3e-31	2

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
TMF1-201	ENST00000398559	6879	1093aa	ENSP00000381567
TMF1-206	ENST00000646304	6546	985aa	ENSP00000496378
TMF1-207	ENST00000646708	4867	1096aa	ENSP00000494067
TMF1-203	ENST00000488010	3399	775aa	ENSP00000419330
TMF1-204	ENST00000489370	372	No protein	-
TMF1-205	ENST00000645406	1215	No protein	-
TMF1-202	ENST00000477872	222	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000139	located_in Golgi membrane	1	IEA	Homo_sapiens(9606)	Component
GO:0001675	involved_in acrosome assembly	1	IEA	Homo_sapiens(9606)	Process
GO:0001819	involved_in positive regulation of cytokine production	1	IEA	Homo_sapiens(9606)	Process
GO:0003677	enables DNA binding	1	IEA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	located_in nucleus	1	IEA	Homo_sapiens(9606)	Component
GO:0005783	is_active_in endoplasmic reticulum	1	IBA	Homo_sapiens(9606)	Component
GO:0005794	is_active_in Golgi apparatus	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0005829	located_in cytosol	1	TAS	Homo_sapiens(9606)	Component
GO:0007289	involved_in spermatid nucleus differentiation	1	IEA	Homo_sapiens(9606)	Process
GO:0010629	involved_in negative regulation of gene expression	1	IEA	Homo_sapiens(9606)	Process
GO:0030317	involved_in flagellated sperm motility	1	IEA	Homo_sapiens(9606)	Process
GO:0030374	enables nuclear receptor coactivator activity	1	IDA	Homo_sapiens(9606)	Function
GO:0030521	involved_in androgen receptor signaling pathway	1	IDA	Homo_sapiens(9606)	Process
GO:0032275	involved_in luteinizing hormone secretion	1	IEA	Homo_sapiens(9606)	Process
GO:0033327	involved_in Leydig cell differentiation	1	IEA	Homo_sapiens(9606)	Process
GO:0042742	involved_in defense response to bacterium	1	IEA	Homo_sapiens(9606)	Process
GO:0045944	involved_in positive regulation of transcription by RNA polymerase II	1	IDA	Homo_sapiens(9606)	Process
GO:0050681	enables nuclear androgen receptor binding	1	IPI	Homo_sapiens(9606)	Function
GO:0061136	involved_in regulation of proteasomal protein catabolic process	1	ISS	Homo_sapiens(9606)	Process
GO:1904019	involved_in epithelial cell apoptotic process	1	IEA	Homo_sapiens(9606)	Process
GO:1904036	involved_in negative regulation of epithelial cell apoptotic process	1	IEA	Homo_sapiens(9606)	Process
GO:2000845	involved_in positive regulation of testosterone secretion	1	IEA	Homo_sapiens(9606)	Process