Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerCHIKVSARS-COV-OC43FlavivirusesHIVIAVRVSARS-COV-2SINVDengueZika
Drug Drug
Main interacting RNAs mRNA
Moonlighting functions E3 ligase
Localizations Nucleoli
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000143799 Gene ID 142 Accession 270
Symbol PARP1 Alias PARP;PARS;PPOL;ADPRT;ARTD1;ADPRT1;PARP-1;ADPRT1;pADPRT-1;Poly-PARP Full Name poly(ADP-ribose) polymerase 1
Status Confidence Length 47410 bases Strand Minus strand
Position 1 : 226360691 - 226408100 RNA binding domain PARP
Summary This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000503396 PARP PF00644 5.1e-73 1
ENSP00000355759 PARP PF00644 5.4e-73 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
PARP1-215 ENST00000677189 2348 No protein -
PARP1-220 ENST00000677985 2285 No protein -
PARP1-223 ENST00000678288 2420 No protein -
PARP1-222 ENST00000678226 3274 No protein -
PARP1-210 ENST00000676481 1371 No protein -
PARP1-203 ENST00000366794 3978 1014aa ENSP00000355759
PARP1-224 ENST00000678560 4255 100aa ENSP00000503293
PARP1-219 ENST00000677884 4620 No protein -
PARP1-216 ENST00000677203 3850 971aa ENSP00000503396
PARP1-211 ENST00000676565 3577 No protein -
PARP1-221 ENST00000678144 3719 308aa ENSP00000504430
PARP1-214 ENST00000677091 3768 369aa ENSP00000504745
PARP1-225 ENST00000678781 5430 No protein -
PARP1-212 ENST00000676685 6210 No protein -
PARP1-226 ENST00000679276 4918 No protein -
PARP1-209 ENST00000498787 5629 No protein -
PARP1-213 ENST00000676709 4764 No protein -
PARP1-207 ENST00000490921 3165 No protein -
PARP1-204 ENST00000463968 830 No protein -
PARP1-208 ENST00000491816 416 No protein -
PARP1-205 ENST00000468608 438 No protein -
PARP1-217 ENST00000677374 5697 No protein -
PARP1-218 ENST00000677815 3770 No protein -
PARP1-206 ENST00000469663 542 No protein -
PARP1-202 ENST00000366792 553 No protein -
PARP1-201 ENST00000366790 3358 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
75382Melanoma9E-821983785

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000143799homo_sapiensENSP000003929726039.1228homo_sapiensENSP0000035575933.727821.9921
ENSG00000143799homo_sapiensENSP0000038174049.155732.0826homo_sapiensENSP0000035575925.838316.8639

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000143799homo_sapiensENSP0000035575992.899492.2091nomascus_leucogenysENSNLEP0000001688199.367198.6287
ENSG00000143799homo_sapiensENSP0000035575999.802899.4083pan_paniscusENSPPAP0000003616899.802899.4083
ENSG00000143799homo_sapiensENSP0000035575999.802899.4083pongo_abeliiENSPPYP0000000016299.802899.4083
ENSG00000143799homo_sapiensENSP0000035575999.802899.4083pan_troglodytesENSPTRP0000000345799.802899.4083
ENSG00000143799homo_sapiensENSP0000035575910099.6055gorilla_gorillaENSGGOP0000002558210099.6055
ENSG00000143799homo_sapiensENSP0000035575989.64584.0237ornithorhynchus_anatinusENSOANP0000000236781.965776.826
ENSG00000143799homo_sapiensENSP0000035575989.743683.1361sarcophilus_harrisiiENSSHAP000000022409184.3
ENSG00000143799homo_sapiensENSP0000035575961.439857.8895notamacropus_eugeniiENSMEUP0000000705380.699576.0363
ENSG00000143799homo_sapiensENSP0000035575955.424153.5503choloepus_hoffmanniENSCHOP0000000314555.533653.6561
ENSG00000143799homo_sapiensENSP0000035575991.814688.3629dasypus_novemcinctusENSDNOP0000000936695.979492.3711
ENSG00000143799homo_sapiensENSP0000035575992.899488.9546erinaceus_europaeusENSEEUP0000001121992.716588.7795
ENSG00000143799homo_sapiensENSP0000035575973.767369.428echinops_telfairiENSETEP0000001075073.261568.952
ENSG00000143799homo_sapiensENSP0000035575996.646995.069callithrix_jacchusENSCJAP0000007240594.230892.6923
ENSG00000143799homo_sapiensENSP0000035575999.21198.2249cercocebus_atysENSCATP0000003175799.21198.2249
ENSG00000143799homo_sapiensENSP0000035575999.013898.1262macaca_fascicularisENSMFAP0000000574099.013898.1262
ENSG00000143799homo_sapiensENSP0000035575999.013898.1262macaca_mulattaENSMMUP0000002873799.013898.1262
ENSG00000143799homo_sapiensENSP0000035575999.21198.2249macaca_nemestrinaENSMNEP0000002054499.21198.2249
ENSG00000143799homo_sapiensENSP0000035575999.112498.1262papio_anubisENSPANP0000000362994.72293.7795
ENSG00000143799homo_sapiensENSP0000035575997.337396.2525mandrillus_leucophaeusENSMLEP0000000297397.050195.9685
ENSG00000143799homo_sapiensENSP0000035575991.814688.5602tursiops_truncatusENSTTRP0000000017492.08788.8229
ENSG00000143799homo_sapiensENSP0000035575992.899490.3353vulpes_vulpesENSVVUP0000000203096.913694.2387
ENSG00000143799homo_sapiensENSP0000035575995.85892.5049mus_spretusMGP_SPRETEiJ_P002267495.85892.5049
ENSG00000143799homo_sapiensENSP0000035575997.238795.1677equus_asinusENSEASP0000504738997.238795.1677
ENSG00000143799homo_sapiensENSP0000035575993.491189.1519capra_hircusENSCHIP0000001900792.941288.6274
ENSG00000143799homo_sapiensENSP0000035575991.814687.7712loxodonta_africanaENSLAFP0000000657595.585291.3758
ENSG00000143799homo_sapiensENSP0000035575995.85892.4063panthera_leoENSPLOP0000000869495.952692.4975
ENSG00000143799homo_sapiensENSP0000035575988.658885.6016ailuropoda_melanoleucaENSAMEP0000001530796.252792.9336
ENSG00000143799homo_sapiensENSP0000035575994.773290.8284bos_indicus_hybridENSBIXP0000504364594.586690.6496
ENSG00000143799homo_sapiensENSP0000035575997.633194.5759oryctolagus_cuniculusENSOCUP0000001530597.729594.6693
ENSG00000143799homo_sapiensENSP0000035575997.238795.1677equus_caballusENSECAP0000003191890.791988.8582
ENSG00000143799homo_sapiensENSP0000035575997.1494.3787canis_lupus_familiarisENSCAFP0084501134897.1494.3787
ENSG00000143799homo_sapiensENSP0000035575992.209188.7574panthera_pardusENSPPRP0000000886596.094692.4974
ENSG00000143799homo_sapiensENSP0000035575997.92995.2663marmota_marmota_marmotaENSMMMP0000002756597.92995.2663
ENSG00000143799homo_sapiensENSP0000035575997.1494.0828balaenoptera_musculusENSBMSP0001000300397.235994.1757
ENSG00000143799homo_sapiensENSP0000035575996.449792.998cavia_porcellusENSCPOP0000001410996.735993.274
ENSG00000143799homo_sapiensENSP0000035575992.603689.4477felis_catusENSFCAP0000000536695.914292.6456
ENSG00000143799homo_sapiensENSP0000035575992.99890.0394ursus_americanusENSUAMP0000001812796.717993.641
ENSG00000143799homo_sapiensENSP0000035575991.321584.8126monodelphis_domesticaENSMODP0000000753591.411784.8963
ENSG00000143799homo_sapiensENSP0000035575994.773290.6312bison_bison_bisonENSBBBP0000001905594.866790.7206
ENSG00000143799homo_sapiensENSP0000035575996.942893.6884monodon_monocerosENSMMNP0001501171297.038593.7808
ENSG00000143799homo_sapiensENSP0000035575997.041494.5759sus_scrofaENSSSCP0000002210496.755294.297
ENSG00000143799homo_sapiensENSP0000035575993.984292.1105microcebus_murinusENSMICP0000001555697.443895.501
ENSG00000143799homo_sapiensENSP0000035575994.674690.4339octodon_degusENSODEP0000000992895.143790.8821
ENSG00000143799homo_sapiensENSP0000035575995.463591.3215jaculus_jaculusENSJJAP0000002386095.463591.3215
ENSG00000143799homo_sapiensENSP0000035575995.167791.4201ovis_aries_rambouilletENSOARP0002002450694.980391.2402
ENSG00000143799homo_sapiensENSP0000035575984.319580.3748ursus_maritimusENSUMAP0000002055188.78584.6314
ENSG00000143799homo_sapiensENSP0000035575997.238793.5897ochotona_princepsENSOPRP0000001070697.238793.5897
ENSG00000143799homo_sapiensENSP0000035575997.041493.787delphinapterus_leucasENSDLEP0000000222097.137293.8796
ENSG00000143799homo_sapiensENSP0000035575997.238794.5759physeter_catodonENSPCTP0000500147697.334694.6693
ENSG00000143799homo_sapiensENSP0000035575995.759492.5049mus_caroliMGP_CAROLIEiJ_P002160995.759492.5049
ENSG00000143799homo_sapiensENSP0000035575995.85892.5049mus_musculusENSMUSP0000002777795.85892.5049
ENSG00000143799homo_sapiensENSP0000035575992.800887.7712dipodomys_ordiiENSDORP0000000489794.189
ENSG00000143799homo_sapiensENSP0000035575996.548392.8008mustela_putorius_furoENSMPUP0000000455096.643692.8924
ENSG00000143799homo_sapiensENSP0000035575996.548394.8718aotus_nancymaaeENSANAP0000002998494.134692.5
ENSG00000143799homo_sapiensENSP0000035575996.351194.3787saimiri_boliviensis_boliviensisENSSBOP0000000195491.996290.113
ENSG00000143799homo_sapiensENSP0000035575980.867978.7968vicugna_pacosENSVPAP0000001063081.107879.0307
ENSG00000143799homo_sapiensENSP0000035575969.132168.4418chlorocebus_sabaeusENSCSAP0000001241998.871797.8843
ENSG00000143799homo_sapiensENSP0000035575977.71275.9369tupaia_belangeriENSTBEP0000000206487.458485.4606
ENSG00000143799homo_sapiensENSP0000035575995.85893.0966mesocricetus_auratusENSMAUP0000000633195.952693.1885
ENSG00000143799homo_sapiensENSP0000035575997.1493.5897phocoena_sinusENSPSNP0000000487097.235993.6821
ENSG00000143799homo_sapiensENSP0000035575995.266392.7022camelus_dromedariusENSCDRP0000500578194.891992.3379
ENSG00000143799homo_sapiensENSP0000035575988.85686.6864carlito_syrichtaENSTSYP0000000340798.041495.6474
ENSG00000143799homo_sapiensENSP0000035575977.810773.8659panthera_tigris_altaicaENSPTIP0000000749489.965885.4048
ENSG00000143799homo_sapiensENSP0000035575995.364991.8146rattus_norvegicusENSRNOP0000000423295.364991.8146
ENSG00000143799homo_sapiensENSP0000035575997.435994.8718prolemur_simusENSPSMP0000000620897.628595.0593
ENSG00000143799homo_sapiensENSP0000035575995.759492.7022microtus_ochrogasterENSMOCP0000001498495.853992.7937
ENSG00000143799homo_sapiensENSP0000035575952.465550.9862sorex_araneusENSSARP0000000854157.952156.3181
ENSG00000143799homo_sapiensENSP0000035575994.871892.0118peromyscus_maniculatus_bairdiiENSPEMP0000002307195.816792.9283
ENSG00000143799homo_sapiensENSP0000035575910.65099.76331bos_mutusENSBMUP0000001174878.832172.2628
ENSG00000143799homo_sapiensENSP0000035575967.652963.5108bos_mutusENSBMUP0000002009884.691479.5062
ENSG00000143799homo_sapiensENSP0000035575994.082890.7298mus_spicilegusENSMSIP0000000839695.783192.3695
ENSG00000143799homo_sapiensENSP0000035575996.055293.1953cricetulus_griseus_chok1gshdENSCGRP0000102183696.1593.2873
ENSG00000143799homo_sapiensENSP0000035575978.895575.1479pteropus_vampyrusENSPVAP0000000524979.129675.3709
ENSG00000143799homo_sapiensENSP0000035575974.35968.146myotis_lucifugusENSMLUP0000001119183.499476.5227
ENSG00000143799homo_sapiensENSP0000035575991.124384.9112vombatus_ursinusENSVURP0001002110391.304385.079
ENSG00000143799homo_sapiensENSP0000035575991.124384.9112vombatus_ursinusENSVURP0001001150791.304385.079
ENSG00000143799homo_sapiensENSP0000035575996.844293.3925rhinolophus_ferrumequinumENSRFEP0001002113796.844293.3925
ENSG00000143799homo_sapiensENSP0000035575996.548392.7022neovison_visonENSNVIP0000001894296.643692.7937
ENSG00000143799homo_sapiensENSP0000035575993.392589.0533bos_taurusENSBTAP0000005940992.210387.926
ENSG00000143799homo_sapiensENSP0000035575995.660891.716heterocephalus_glaber_femaleENSHGLP0000000544696.230292.2619
ENSG00000143799homo_sapiensENSP0000035575998.915297.929rhinopithecus_bietiENSRBIP0000004345998.915297.929
ENSG00000143799homo_sapiensENSP0000035575997.1494.2801canis_lupus_dingoENSCAFP0002000367797.1494.2801
ENSG00000143799homo_sapiensENSP0000035575997.830495.4635sciurus_vulgarisENSSVLP0000501283597.926995.5577
ENSG00000143799homo_sapiensENSP0000035575991.321584.714phascolarctos_cinereusENSPCIP0000000769791.321584.714
ENSG00000143799homo_sapiensENSP0000035575956.21353.1558procavia_capensisENSPCAP0000000530056.268553.2083
ENSG00000143799homo_sapiensENSP0000035575996.055292.6036nannospalax_galiliENSNGAP0000000340496.1592.695
ENSG00000143799homo_sapiensENSP0000035575994.773290.927bos_grunniensENSBGRP0000000862694.586690.748
ENSG00000143799homo_sapiensENSP0000035575996.153893.0966chinchilla_lanigeraENSCLAP0000000956896.248893.1885
ENSG00000143799homo_sapiensENSP0000035575995.06991.5187cervus_hanglu_yarkandensisENSCHYP0000001428494.881991.3386
ENSG00000143799homo_sapiensENSP0000035575996.844293.5897catagonus_wagneriENSCWAP0000000378896.463793.222
ENSG00000143799homo_sapiensENSP0000035575998.027695.5621ictidomys_tridecemlineatusENSSTOP0000001432298.027695.5621
ENSG00000143799homo_sapiensENSP0000035575996.942893.4911otolemur_garnettiiENSOGAP0000001634296.656893.2153
ENSG00000143799homo_sapiensENSP0000035575998.422196.9428cebus_imitatorENSCCAP0000003086198.519297.0385
ENSG00000143799homo_sapiensENSP0000035575988.264386.0947urocitellus_parryiiENSUPAP0001000275397.600995.2017
ENSG00000143799homo_sapiensENSP0000035575995.266391.716moschus_moschiferusENSMMSP0000002535395.078791.5354
ENSG00000143799homo_sapiensENSP0000035575998.915297.929rhinopithecus_roxellanaENSRROP0000000971498.915297.929
ENSG00000143799homo_sapiensENSP000003557599.467469.07298mus_pahariMGP_PahariEiJ_P007685997.959293.8775
ENSG00000143799homo_sapiensENSP0000035575997.633194.7732propithecus_coquereliENSPCOP0000001088397.633194.7732
ENSG00000143799homo_sapiensENSP0000035575950.098632.643caenorhabditis_elegansY71F9AL.18a.253.756635.0265
ENSG00000143799homo_sapiensENSP0000035575959.368841.4201drosophila_melanogasterFBpp011260860.563442.2535
ENSG00000143799homo_sapiensENSP0000035575936.291927.9093ciona_intestinalisENSCINP0000003444777.966159.9576
ENSG00000143799homo_sapiensENSP0000035575921.794916.7653petromyzon_marinusENSPMAP0000001051063.872849.1329
ENSG00000143799homo_sapiensENSP0000035575973.274258.4813eptatretus_burgeriENSEBUP0000000899671.5857.1291
ENSG00000143799homo_sapiensENSP0000035575980.078967.0611callorhinchus_miliiENSCMIP0000001396278.454165.7005
ENSG00000143799homo_sapiensENSP0000035575970.414259.7633latimeria_chalumnaeENSLACP0000000305670.623159.9407
ENSG00000143799homo_sapiensENSP0000035575983.92573.0769lepisosteus_oculatusENSLOCP0000001945284.340973.439
ENSG00000143799homo_sapiensENSP0000035575983.530671.0059clupea_harengusENSCHAP0000001715082.714870.3125
ENSG00000143799homo_sapiensENSP0000035575984.122371.499danio_rerioENSDARP0000000836484.205371.5696
ENSG00000143799homo_sapiensENSP0000035575981.85468.9349carassius_auratusENSCARP0000010201078.747666.3188
ENSG00000143799homo_sapiensENSP0000035575984.615471.0059carassius_auratusENSCARP0000010894084.365870.7965
ENSG00000143799homo_sapiensENSP0000035575981.360968.5404carassius_auratusENSCARP0000008783480.019467.4103
ENSG00000143799homo_sapiensENSP0000035575983.234770.217astyanax_mexicanusENSAMXP0000000664282.664169.7355
ENSG00000143799homo_sapiensENSP0000035575983.333369.7239ictalurus_punctatusENSIPUP0000003000783.005969.4499
ENSG00000143799homo_sapiensENSP0000035575983.43271.7949esox_luciusENSELUP0000001764483.679572.0079
ENSG00000143799homo_sapiensENSP0000035575983.136170.8087electrophorus_electricusENSEEEP0000003007383.300470.9486
ENSG00000143799homo_sapiensENSP0000035575983.629270.5128oncorhynchus_kisutchENSOKIP0000504792183.464670.374
ENSG00000143799homo_sapiensENSP0000035575983.136170.1183oncorhynchus_mykissENSOMYP0000005300483.218270.1876
ENSG00000143799homo_sapiensENSP0000035575982.741670.1183salmo_salarENSSSAP0000005332083.069370.396
ENSG00000143799homo_sapiensENSP0000035575981.163768.2446salmo_truttaENSSTUP0000006252381.083768.1773
ENSG00000143799homo_sapiensENSP0000035575982.938970.1183gadus_morhuaENSGMOP0000002841083.020770.1876
ENSG00000143799homo_sapiensENSP0000035575984.319570.7101fundulus_heteroclitusENSFHEP0000000040284.236570.6404
ENSG00000143799homo_sapiensENSP0000035575984.122371.3018poecilia_reticulataENSPREP0000000159684.039471.2315
ENSG00000143799homo_sapiensENSP0000035575984.122370.3156xiphophorus_maculatusENSXMAP0000000363984.039470.2463
ENSG00000143799homo_sapiensENSP0000035575983.826470.4142oryzias_latipesENSORLP0000001717683.743870.3448
ENSG00000143799homo_sapiensENSP0000035575983.727870.0197cyclopterus_lumpusENSCLMP0000502192383.727870.0197
ENSG00000143799homo_sapiensENSP0000035575984.319571.8935oreochromis_niloticusENSONIP0000007498383.577771.261
ENSG00000143799homo_sapiensENSP0000035575984.812672.0907haplochromis_burtoniENSHBUP0000000893984.812672.0907
ENSG00000143799homo_sapiensENSP0000035575984.122371.6963astatotilapia_callipteraENSACLP0000002291985.385472.7728
ENSG00000143799homo_sapiensENSP0000035575984.122371.9921sparus_aurataENSSAUP0001004943984.122371.9921
ENSG00000143799homo_sapiensENSP0000035575984.418171.4004lates_calcariferENSLCAP0001002123384.418171.4004
ENSG00000143799homo_sapiensENSP0000035575986.094774.9507xenopus_tropicalisENSXETP0000008117586.179775.0247
ENSG00000143799homo_sapiensENSP0000035575988.560280.3748chrysemys_picta_belliiENSCPBP0000001621188.822980.6133
ENSG00000143799homo_sapiensENSP0000035575984.615476.43sphenodon_punctatusENSSPUP0000001008087.195178.7602
ENSG00000143799homo_sapiensENSP0000035575987.771278.9941crocodylus_porosusENSCPRP0000500475688.031779.2285
ENSG00000143799homo_sapiensENSP0000035575970.019761.144laticauda_laticaudataENSLLTP0000001451588.418477.2105
ENSG00000143799homo_sapiensENSP0000035575986.193375.1479notechis_scutatusENSNSUP0000001315886.620475.5203
ENSG00000143799homo_sapiensENSP0000035575986.291975.1479pseudonaja_textilisENSPTXP0000001853986.633775.4455
ENSG00000143799homo_sapiensENSP0000035575985.404376.6272anas_platyrhynchos_platyrhynchosENSAPLP0000001400687.298478.3266
ENSG00000143799homo_sapiensENSP0000035575987.771277.712gallus_gallusENSGALP0001002477885.330875.5513
ENSG00000143799homo_sapiensENSP0000035575984.911276.0355meleagris_gallopavoENSMGAP0000001953088.854579.5666
ENSG00000143799homo_sapiensENSP0000035575986.587876.7258serinus_canariaENSSCAP0000002148787.276377.336
ENSG00000143799homo_sapiensENSP0000035575988.264379.1913parus_majorENSPMJP0000001555488.264379.1913
ENSG00000143799homo_sapiensENSP0000035575987.179577.3176anolis_carolinensisENSACAP0000003623487.872877.9324
ENSG00000143799homo_sapiensENSP0000035575984.220971.5976neolamprologus_brichardiENSNBRP0000002280285.485572.6727
ENSG00000143799homo_sapiensENSP0000035575986.489275.9369naja_najaENSNNAP0000000007486.745876.1622
ENSG00000143799homo_sapiensENSP0000035575986.982277.8107podarcis_muralisENSPMRP0000000366687.413378.1962
ENSG00000143799homo_sapiensENSP0000035575983.727874.1617geospiza_fortisENSGFOP0000001075380.550371.3473
ENSG00000143799homo_sapiensENSP0000035575984.911276.0355taeniopygia_guttataENSTGUP0000000442588.580279.321
ENSG00000143799homo_sapiensENSP000003557597.790936.50888erpetoichthys_calabaricusENSECRP0000000585182.291768.75
ENSG00000143799homo_sapiensENSP0000035575984.023771.6963kryptolebias_marmoratusENSKMAP0000001558183.940971.6256
ENSG00000143799homo_sapiensENSP0000035575987.376777.6134salvator_merianaeENSSMRP0000000137687.290677.5369
ENSG00000143799homo_sapiensENSP0000035575983.826470.4142oryzias_javanicusENSOJAP0000003454383.743870.3448
ENSG00000143799homo_sapiensENSP0000035575983.234770.217amphilophus_citrinellusENSACIP0000000725583.813370.7051
ENSG00000143799homo_sapiensENSP0000035575983.826471.2032dicentrarchus_labraxENSDLAP0000504292483.661471.063
ENSG00000143799homo_sapiensENSP0000035575984.418171.6963amphiprion_perculaENSAPEP0000000678284.418171.6963
ENSG00000143799homo_sapiensENSP0000035575983.92570.3156oryzias_sinensisENSOSIP0000001737683.842470.2463
ENSG00000143799homo_sapiensENSP0000035575984.812676.3314pelodiscus_sinensisENSPSIP0000001871288.205179.3846
ENSG00000143799homo_sapiensENSP0000035575988.461579.5858gopherus_evgoodeiENSGEVP0000502085688.72479.822
ENSG00000143799homo_sapiensENSP0000035575988.461579.783chelonoidis_abingdoniiENSCABP0000000326788.72480.0198
ENSG00000143799homo_sapiensENSP0000035575984.023770.7101seriola_dumeriliENSSDUP0000002291384.023770.7101
ENSG00000143799homo_sapiensENSP0000035575983.136169.5266cottoperca_gobioENSCGOP0000004059982.890969.3215
ENSG00000143799homo_sapiensENSP0000035575986.094776.6272struthio_camelus_australisENSSCUP0000000410385.337275.9531
ENSG00000143799homo_sapiensENSP0000035575987.968479.2899anser_brachyrhynchusENSABRP0000001946388.404479.6829
ENSG00000143799homo_sapiensENSP0000035575984.023769.8225gasterosteus_aculeatusENSGACP0000001496083.858369.685
ENSG00000143799homo_sapiensENSP0000035575984.319570.4142cynoglossus_semilaevisENSCSEP0000003221284.236570.3448
ENSG00000143799homo_sapiensENSP0000035575983.234770.6114poecilia_formosaENSPFOP0000000261183.152770.5419
ENSG00000143799homo_sapiensENSP0000035575983.43270.9073myripristis_murdjanENSMMDP0000504591384.769572.0441
ENSG00000143799homo_sapiensENSP0000035575983.43270.7101sander_luciopercaENSSLUP0000005702483.267770.5709
ENSG00000143799homo_sapiensENSP0000035575988.362979.1913strigops_habroptilaENSSHBP0000502375588.625179.4263
ENSG00000143799homo_sapiensENSP0000035575984.418171.6963amphiprion_ocellarisENSAOCP0000003015684.418171.6963
ENSG00000143799homo_sapiensENSP0000035575988.560280.4734terrapene_carolina_triunguisENSTMTP0000001978388.822980.7122
ENSG00000143799homo_sapiensENSP0000035575910.45368.38264hucho_huchoENSHHUP0000000739075.177360.2837
ENSG00000143799homo_sapiensENSP0000035575982.445870.6114betta_splendensENSBSLP0000004138882.445870.6114
ENSG00000143799homo_sapiensENSP0000035575984.418171.4004pygocentrus_nattereriENSPNAP0000000776183.839470.9109
ENSG00000143799homo_sapiensENSP0000035575983.234770.4142anabas_testudineusENSATEP0000005352582.341569.6585
ENSG00000143799homo_sapiensENSP0000035575916.469413.1164ciona_savignyiENSCSAVP0000000778978.773662.7358
ENSG00000143799homo_sapiensENSP0000035575983.92570.7101seriola_lalandi_dorsalisENSSLDP0000000811183.92570.7101
ENSG00000143799homo_sapiensENSP0000035575983.92571.3018labrus_bergyltaENSLBEP0000001740984.007971.3722
ENSG00000143799homo_sapiensENSP0000035575984.122371.6963pundamilia_nyerereiENSPNYP0000001284885.385472.7728
ENSG00000143799homo_sapiensENSP0000035575984.418171.6963mastacembelus_armatusENSMAMP0000003064684.752571.9802
ENSG00000143799homo_sapiensENSP0000035575982.051369.5266stegastes_partitusENSSPAP0000002532083.116970.4296
ENSG00000143799homo_sapiensENSP0000035575982.938969.8225oncorhynchus_tshawytschaENSOTSP0000504766082.857169.7537
ENSG00000143799homo_sapiensENSP0000035575925.739621.499oncorhynchus_tshawytschaENSOTSP0000505762880.80567.4923
ENSG00000143799homo_sapiensENSP0000035575983.826471.0059acanthochromis_polyacanthusENSAPOP0000000474983.826471.0059
ENSG00000143799homo_sapiensENSP0000035575988.264379.1913aquila_chrysaetos_chrysaetosENSACCP0002001894288.264379.1913
ENSG00000143799homo_sapiensENSP0000035575982.64369.6252nothobranchius_furzeriENSNFUP0001500967283.134970.0397
ENSG00000143799homo_sapiensENSP0000035575980.57267.6529cyprinodon_variegatusENSCVAP0000003177883.452570.0715
ENSG00000143799homo_sapiensENSP0000035575983.629271.5976denticeps_clupeoidesENSDCDP0000005940983.382571.3864
ENSG00000143799homo_sapiensENSP0000035575984.023771.5976larimichthys_croceaENSLCRP0000501486584.023771.5976
ENSG00000143799homo_sapiensENSP0000035575982.248569.0335takifugu_rubripesENSTRUP0000004929579.656266.8577
ENSG00000143799homo_sapiensENSP0000035575985.700276.43ficedula_albicollisENSFALP0000002115086.295976.9613
ENSG00000143799homo_sapiensENSP0000035575982.938970.3156hippocampus_comesENSHCOP0000002323482.45169.902
ENSG00000143799homo_sapiensENSP0000035575984.023770.6114cyprinus_carpio_carpioENSCCRP0000004151269.721858.5925
ENSG00000143799homo_sapiensENSP0000035575984.023771.3018cyprinus_carpio_carpioENSCCRP0000007334283.858371.1614
ENSG00000143799homo_sapiensENSP0000035575987.278177.3176coturnix_japonicaENSCJPP0000500670886.510376.6373
ENSG00000143799homo_sapiensENSP0000035575984.220971.1045poecilia_latipinnaENSPLAP0000000014684.137971.0345
ENSG00000143799homo_sapiensENSP0000035575971.893560.2564sinocyclocheilus_grahamiENSSGRP0000007825276.736864.3158
ENSG00000143799homo_sapiensENSP0000035575974.753462.5247sinocyclocheilus_grahamiENSSGRP0000005947383.480269.8238
ENSG00000143799homo_sapiensENSP0000035575984.812672.288maylandia_zebraENSMZEP0000502259384.812672.288
ENSG00000143799homo_sapiensENSP0000035575983.333370.3156tetraodon_nigroviridisENSTNIP0000001948182.76269.8335
ENSG00000143799homo_sapiensENSP0000035575982.741671.1045paramormyrops_kingsleyaeENSPKIP0000002187282.987171.3155
ENSG00000143799homo_sapiensENSP0000035575983.727871.8935scleropages_formosusENSSFOP0001503126883.645371.8227
ENSG00000143799homo_sapiensENSP0000035575985.207171.8935leptobrachium_leishanenseENSLLEP0000002460585.459972.1068
ENSG00000143799homo_sapiensENSP0000035575984.319571.2032scophthalmus_maximusENSSMAP0000006205584.319571.2032
ENSG00000143799homo_sapiensENSP000003557598.18547.00197oryzias_melastigmaENSOMEP0000000673379.807768.2692
ENSG00000143799homo_sapiensENSP0000035575932.938928.4024oryzias_melastigmaENSOMEP0000000674784.55772.9114

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000122involved_in negative regulation of transcription by RNA polymerase II2IDA,TASHomo_sapiens(9606)Process
GO:0000723involved_in telomere maintenance1TASHomo_sapiens(9606)Process
GO:0000781located_in chromosome, telomeric region1HDAHomo_sapiens(9606)Component
GO:0000785part_of chromatin1IDAHomo_sapiens(9606)Component
GO:0003677enables DNA binding1IDAHomo_sapiens(9606)Function
GO:0003682enables chromatin binding1IDAHomo_sapiens(9606)Function
GO:0003684enables damaged DNA binding1IDAHomo_sapiens(9606)Function
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0003950enables NAD+ ADP-ribosyltransferase activity4IBA,IDA,IMP,TASHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus2IDAHomo_sapiens(9606)Component
GO:0005635located_in nuclear envelope1IDAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005667part_of transcription regulator complex1IDAHomo_sapiens(9606)Component
GO:0005730is_active_in nucleolus2IBA,IDAHomo_sapiens(9606)Component
GO:0005739located_in mitochondrion1IDAHomo_sapiens(9606)Component
GO:0005829is_active_in cytosol1IDAHomo_sapiens(9606)Component
GO:0006281involved_in DNA repair2IDA,TASHomo_sapiens(9606)Process
GO:0006302involved_in double-strand break repair3IBA,IDA,IMPHomo_sapiens(9606)Process
GO:0006366involved_in transcription by RNA polymerase II1TASHomo_sapiens(9606)Process
GO:0006915involved_in apoptotic process1IDAHomo_sapiens(9606)Process
GO:0006974involved_in DNA damage response3IDA,IMPHomo_sapiens(9606)Process
GO:0007005acts_upstream_of_or_within mitochondrion organization1IMPHomo_sapiens(9606)Process
GO:0007179involved_in transforming growth factor beta receptor signaling pathway1IEAHomo_sapiens(9606)Process
GO:0008270enables zinc ion binding1IDAHomo_sapiens(9606)Function
GO:0010332involved_in response to gamma radiation1IEAHomo_sapiens(9606)Process
GO:0010613involved_in positive regulation of cardiac muscle hypertrophy1ISSHomo_sapiens(9606)Process
GO:0016020located_in membrane1HDAHomo_sapiens(9606)Component
GO:0016051involved_in carbohydrate biosynthetic process1IEAHomo_sapiens(9606)Process
GO:0016540involved_in protein autoprocessing1IEAHomo_sapiens(9606)Process
GO:0016604located_in nuclear body1IDAHomo_sapiens(9606)Component
GO:0016779enables nucleotidyltransferase activity1IEAHomo_sapiens(9606)Function
GO:0019899enables enzyme binding1IPIHomo_sapiens(9606)Function
GO:0019901enables protein kinase binding1IPIHomo_sapiens(9606)Function
GO:0023019involved_in signal transduction involved in regulation of gene expression1IEAHomo_sapiens(9606)Process
GO:0030225involved_in macrophage differentiation1TASHomo_sapiens(9606)Process
GO:0030331enables nuclear estrogen receptor binding1IEAHomo_sapiens(9606)Function
GO:0030592involved_in DNA ADP-ribosylation1IDAHomo_sapiens(9606)Process
GO:0031491enables nucleosome binding1IDAHomo_sapiens(9606)Function
GO:0031625enables ubiquitin protein ligase binding1IEAHomo_sapiens(9606)Function
GO:0032042acts_upstream_of_or_within mitochondrial DNA metabolic process1IMPHomo_sapiens(9606)Process
GO:0032786involved_in positive regulation of DNA-templated transcription, elongation1IDAHomo_sapiens(9606)Process
GO:0032869involved_in cellular response to insulin stimulus1IDAHomo_sapiens(9606)Process
GO:0032880acts_upstream_of_or_within regulation of protein localization1IMPHomo_sapiens(9606)Process
GO:0032991part_of protein-containing complex1IDAHomo_sapiens(9606)Component
GO:0032993part_of protein-DNA complex1IDAHomo_sapiens(9606)Component
GO:0033148involved_in positive regulation of intracellular estrogen receptor signaling pathway1IEAHomo_sapiens(9606)Process
GO:0034244involved_in negative regulation of transcription elongation by RNA polymerase II1IDAHomo_sapiens(9606)Process
GO:0034599acts_upstream_of_or_within cellular response to oxidative stress1IMPHomo_sapiens(9606)Process
GO:0034644involved_in cellular response to UV1IMPHomo_sapiens(9606)Process
GO:0035861is_active_in site of double-strand break2IDAHomo_sapiens(9606)Component
GO:0036211acts_upstream_of_or_within protein modification process1IMPHomo_sapiens(9606)Process
GO:0042802enables identical protein binding1IPIHomo_sapiens(9606)Function
GO:0042803enables protein homodimerization activity1IDAHomo_sapiens(9606)Function
GO:0042826enables histone deacetylase binding1IEAHomo_sapiens(9606)Function
GO:0043123involved_in positive regulation of I-kappaB kinase/NF-kappaB signaling1IDAHomo_sapiens(9606)Process
GO:0043504acts_upstream_of_or_within mitochondrial DNA repair1IMPHomo_sapiens(9606)Process
GO:0043596is_active_in nuclear replication fork1IDAHomo_sapiens(9606)Component
GO:0044030involved_in regulation of DNA methylation1IEAHomo_sapiens(9606)Process
GO:0045087involved_in innate immune response1IEAHomo_sapiens(9606)Process
GO:0045188involved_in regulation of circadian sleep/wake cycle, non-REM sleep1ISSHomo_sapiens(9606)Process
GO:0045824involved_in negative regulation of innate immune response2IDA,IMPHomo_sapiens(9606)Process
GO:0045892involved_in negative regulation of DNA-templated transcription1ISSHomo_sapiens(9606)Process
GO:0045944involved_in positive regulation of transcription by RNA polymerase II1IDAHomo_sapiens(9606)Process
GO:0046697involved_in decidualization1ISSHomo_sapiens(9606)Process
GO:0050790involved_in regulation of catalytic activity1IDAHomo_sapiens(9606)Process
GO:0051287enables NAD binding1IEAHomo_sapiens(9606)Function
GO:0051901involved_in positive regulation of mitochondrial depolarization1IEAHomo_sapiens(9606)Process
GO:0060391involved_in positive regulation of SMAD protein signal transduction1IEAHomo_sapiens(9606)Process
GO:0060545involved_in positive regulation of necroptotic process1ISSHomo_sapiens(9606)Process
GO:0061629enables RNA polymerase II-specific DNA-binding transcription factor binding1IPIHomo_sapiens(9606)Function
GO:0070212involved_in protein poly-ADP-ribosylation2IBA,IDAHomo_sapiens(9606)Process
GO:0070213involved_in protein auto-ADP-ribosylation1IDAHomo_sapiens(9606)Process
GO:0070412enables R-SMAD binding1IEAHomo_sapiens(9606)Function
GO:0071168involved_in protein localization to chromatin1IDAHomo_sapiens(9606)Process
GO:0071294involved_in cellular response to zinc ion1IEAHomo_sapiens(9606)Process
GO:0071932involved_in replication fork reversal1IDAHomo_sapiens(9606)Process
GO:0090734is_active_in site of DNA damage2IDA,IMPHomo_sapiens(9606)Component
GO:0140294enables NAD DNA ADP-ribosyltransferase activity1IDAHomo_sapiens(9606)Function
GO:0140805enables NAD+-protein-serine ADP-ribosyltransferase activity1IDAHomo_sapiens(9606)Function
GO:0140806enables NAD+- protein-aspartate ADP-ribosyltransferase activity1IDAHomo_sapiens(9606)Function
GO:0140807enables NAD+-protein-glutamate ADP-ribosyltransferase activity1IDAHomo_sapiens(9606)Function
GO:0140808enables NAD+-protein-tyrosine ADP-ribosyltransferase activity1IDAHomo_sapiens(9606)Function
GO:0140815enables NAD+-protein-histidine ADP-ribosyltransferase activity1IDAHomo_sapiens(9606)Function
GO:0140816enables NAD+-histone H2BS6 serine ADP-ribosyltransferase activity1IDAHomo_sapiens(9606)Function
GO:0140817enables NAD+-histone H3S10 serine ADP-ribosyltransferase activity1IDAHomo_sapiens(9606)Function
GO:0140822enables NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity1ISSHomo_sapiens(9606)Function
GO:1900182involved_in positive regulation of protein localization to nucleus1IEAHomo_sapiens(9606)Process
GO:1901216involved_in positive regulation of neuron death1IEAHomo_sapiens(9606)Process
GO:1903376involved_in regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway1IEAHomo_sapiens(9606)Process
GO:1903518involved_in positive regulation of single strand break repair1IGIHomo_sapiens(9606)Process
GO:1904044involved_in response to aldosterone1IEAHomo_sapiens(9606)Process
GO:1904178involved_in negative regulation of adipose tissue development1ISSHomo_sapiens(9606)Process
GO:1904357involved_in negative regulation of telomere maintenance via telomere lengthening1ISSHomo_sapiens(9606)Process
GO:1904646involved_in cellular response to amyloid-beta1IEAHomo_sapiens(9606)Process
GO:1904762involved_in positive regulation of myofibroblast differentiation1IEAHomo_sapiens(9606)Process
GO:1905051involved_in regulation of base-excision repair1IDAHomo_sapiens(9606)Process
GO:1905168involved_in positive regulation of double-strand break repair via homologous recombination1IDAHomo_sapiens(9606)Process
GO:1990090involved_in cellular response to nerve growth factor stimulus1IEAHomo_sapiens(9606)Process
GO:1990404enables NAD+-protein ADP-ribosyltransferase activity2IBA,IDAHomo_sapiens(9606)Function
GO:1990966involved_in ATP generation from poly-ADP-D-ribose1IDAHomo_sapiens(9606)Process
GO:2000679involved_in positive regulation of transcription regulatory region DNA binding1IEAHomo_sapiens(9606)Process
GO:2001170involved_in negative regulation of ATP biosynthetic process1IMPHomo_sapiens(9606)Process

Expression