RBPWorld - a comprehensive database of RNA Binding Proteins

Functions and Diseases

RBP Type	Canonical_RBPs
Diseases	Cancer
Drug	N.A.
Main interacting RNAs	rRNA
Moonlighting functions	N.A.
Localizations	N.A.
BulkPerturb-seq	N.A.

Description

Ensembl ID	ENSG00000143319	Gene ID	81875	Accession	25745
Symbol	ISG20L2	Alias	HSD38	Full Name	interferon stimulated exonuclease gene 20 like 2
Status	Confidence	Length	6876 bases	Strand	Minus strand
Position	1 : 156721891 - 156728766	RNA binding domain	RNase_T
Summary	This gene encodes a 3'-5' exoribonuclease that may be involved in the processing of the 12S pre-rRNA. Pseudogenes have been identified on chromosomes 6 and 11. [provided by RefSeq, Dec 2014]

RNA binding domains (RBDs)

Search:

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000323424	RNase_T	PF00929	3e-11	1
ENSP00000357202	RNase_T	PF00929	3e-11	1

Showing 1 to 2 of 2 entries

RNA binding proteomes (RBPomes)

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Pubmed ID	Full Name	Cell	Author	Time	Doi
22658674	RIC_PMID22658674_Hs_HeLa	HeLa	Alfredo Castello?	2012 Jun 8	doi: 10.1016/j.cell.2012.04.031.?Epub 2012 May 31
27040163	serIC_PMID27040163_Hs_K562	K562	Thomas Conrad?	2016 Apr 4	doi: 10.1038/ncomms11212
27040163	serIC_PMID27040163_Hs_K562.1	K562	Thomas Conrad?	2016 Apr 4	doi: 10.1038/ncomms11212
30528433	XRNAX_PMID30528433_Hs_HEK293	HEK293	Jakob Trendel	2019 Jan 10	doi: 10.1016/j.cell.2018.11.004.?Epub 2018 Dec 6
30528433	XRNAX_PMID30528433_Hs_HeLa	HeLa	Jakob Trendel	2019 Jan 10	doi: 10.1016/j.cell.2018.11.004.?Epub 2018 Dec 6
30528433	XRNAX_PMID30528433_Hs_MCF7	MCF7	Jakob Trendel	2019 Jan 10	doi: 10.1016/j.cell.2018.11.004.?Epub 2018 Dec 6
30799147	cRIC_PMID30799147._Hs_HEK293	HEK293	Manuel Garcia-Moreno	2019 Apr 4	doi: 10.1016/j.molcel.2019.01.017.?Epub 2019 Feb 21
30824702	PtexRIC_PMID30824702_293T_human	293T	Erika C Urdaneta	2019 Mar 1	doi: 10.1038/s41467-019-08942-3
31076284	R.Deep_PMID_31076284_Hs		Maiwen Caudron-Herger	2019 Jul 11	doi: 10.1016/j.molcel.2019.04.018.?Epub 2019 May 7
33235359	RIC_PMID33235359_humanRIC.superset.2021		Fatima Gebauer	2021 Mar	doi: 10.1038/s41576-020-00302-y

Showing 1 to 10 of 12 entries

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Pubmed ID	Title	Author	Time	Journal
No data available in table

Transcripts

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Name	Transcript ID	bp	Protein	Translation ID
ISG20L2-201	ENST00000313146	3303	353aa	ENSP00000323424
ISG20L2-202	ENST00000368219	2985	353aa	ENSP00000357202
ISG20L2-203	ENST00000469074	594	No protein	-
ISG20L2-204	ENST00000470713	635	No protein	-
ISG20L2-205	ENST00000472824	3178	No protein	-
ISG20L2-206	ENST00000496538	872	No protein	-

Showing 1 to 6 of 6 entries

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Gene Model

Click here to download ENSG00000143319's gene model file

ensgID	Trait	pValue	Pubmed ID
No data available in table

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID
No data available in table

Protein-Protein Interaction (PPI)

Click here to download ENSG00000143319's PPI file

Paralogs

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Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000143319	homo_sapiens	ENSP00000361010	32.9384	21.327	homo_sapiens	ENSP00000357202	39.3768	25.4958
ENSG00000143319	homo_sapiens	ENSP00000306565	66.2983	48.6188	homo_sapiens	ENSP00000357202	33.9943	24.9292
ENSG00000143319	homo_sapiens	ENSP00000331944	54.4615	40.9231	homo_sapiens	ENSP00000357202	50.1416	37.6771
ENSG00000143319	homo_sapiens	ENSP00000261377	13.5659	8.13953	homo_sapiens	ENSP00000357202	29.745	17.847
ENSG00000143319	homo_sapiens	ENSP00000170168	11.7117	6.38821	homo_sapiens	ENSP00000357202	40.5099	22.0963

Showing 1 to 5 of 5 entries

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Orthologs

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Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000143319	homo_sapiens	ENSP00000357202	98.3003	97.4504	nomascus_leucogenys	ENSNLEP00000015461	98.0226	97.1751
ENSG00000143319	homo_sapiens	ENSP00000357202	99.7167	99.4334	pan_paniscus	ENSPPAP00000015916	100	99.7159
ENSG00000143319	homo_sapiens	ENSP00000357202	98.8669	98.8669	pongo_abelii	ENSPPYP00000000817	98.5876	98.5876
ENSG00000143319	homo_sapiens	ENSP00000357202	99.7167	99.7167	pan_troglodytes	ENSPTRP00000002486	100	100
ENSG00000143319	homo_sapiens	ENSP00000357202	99.7167	99.4334	gorilla_gorilla	ENSGGOP00000016078	99.435	99.1525
ENSG00000143319	homo_sapiens	ENSP00000357202	58.0737	46.4589	ornithorhynchus_anatinus	ENSOANP00000047676	68.3333	54.6667
ENSG00000143319	homo_sapiens	ENSP00000357202	70.8215	57.7904	sarcophilus_harrisii	ENSSHAP00000018783	51.2295	41.8033
ENSG00000143319	homo_sapiens	ENSP00000357202	52.4079	42.7762	notamacropus_eugenii	ENSMEUP00000000006	64.9123	52.9825
ENSG00000143319	homo_sapiens	ENSP00000357202	90.6516	86.9688	dasypus_novemcinctus	ENSDNOP00000014095	91.6905	87.9656
ENSG00000143319	homo_sapiens	ENSP00000357202	86.4023	84.7026	callithrix_jacchus	ENSCJAP00000015164	91.8675	90.0602

Showing 1 to 10 of 196 entries

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Gene Ontology

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Search:

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000175	enables 3-5-RNA exonuclease activity	1	IEA	Homo_sapiens(9606)	Function
GO:0003723	enables RNA binding	1	HDA	Homo_sapiens(9606)	Function
GO:0004527	enables exonuclease activity	1	IBA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	is_active_in nucleus	1	IBA	Homo_sapiens(9606)	Component
GO:0005730	located_in nucleolus	1	IEA	Homo_sapiens(9606)	Component
GO:0042254	involved_in ribosome biogenesis	1	IEA	Homo_sapiens(9606)	Process

Showing 1 to 7 of 7 entries

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Welcome to

RBP World!

Functions and Diseases

Description

RNA binding domains (RBDs)

RNA binding proteomes (RBPomes)

Literatures on RNA binding capacity

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

Protein-Protein Interaction (PPI)

Paralogs

Orthologs

Gene Ontology

Expression