Functions and Diseases

RBP Type Canonical_RBPs
Diseases CHIKVSARS-COV-OC43FlavivirusesHIVRVSARS-COV-2DengueZika
Drug Drug
Main interacting RNAs rRNA
Moonlighting functions Metabolic enzyme
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000142937 Gene ID 6202 Accession 10441
Symbol RPS8 Alias S8;eS8 Full Name ribosomal protein S8
Status Confidence Length 3240 bases Strand Plus strand
Position 1 : 44775540 - 44778779 RNA binding domain Ribosomal_S8e
Summary Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S8E family of ribosomal proteins. It is located in the cytoplasm. Increased expression of this gene in colorectal tumors and colon polyps compared to matched normal colonic mucosa has been observed. This gene is co-transcribed with the small nucleolar RNA genes U38A, U38B, U39, and U40, which are located in its fourth, fifth, first, and second introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

RNA binding proteomes (RBPomes)

Literatures on RNA binding capacity

Transcripts

Protein-Protein Interaction (PPI)

Orthologs

Gene Ontology

Expression