Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions Metabolic enzyme
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000142453 Gene ID 10498 Accession 23393
Symbol CARM1 Alias PRMT4 Full Name coactivator associated arginine methyltransferase 1
Status Confidence Length 51523 bases Strand Plus strand
Position 19 : 10871553 - 10923075 RNA binding domain MTS
Summary This gene belongs to the protein arginine methyltransferase (PRMT) family. The encoded enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. The enzyme acts specifically on histones and other chromatin-associated proteins and is involved in regulation of gene expression. The enzyme may act in association with other proteins or within multi-protein complexes and may play a role in cell type-specific functions and cell lineage specification. A related pseudogene is located on chromosome 9. [provided by RefSeq, Aug 2013]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000467746 MTS PF05175 8e-08 1
ENSP00000340934 MTS PF05175 1.2e-07 1
ENSP00000325690 MTS PF05175 1.3e-07 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
30456381 CARM1 methylates MED12 to regulate its RNA-binding ability. Donghang Cheng 2018-10-01 Life science alliance
36103286 Carm1 and the Epigenetic Control of Stem Cell Function. John Saber 2022-11-18 Stem cells translational medicine
18413343 The protein arginine methyltransferases CARM1 and PRMT1 cooperate in gene regulation. A Markus Kleinschmidt 2008-06-01 Nucleic acids research
28223985 Arginine Metabolism in Myeloid Cells Shapes Innate and Adaptive Immunity. C Paulo Rodriguez 2017-01-01 Frontiers in immunology
23136128 A novel function for the survival motoneuron protein as a translational regulator. Gabriel Sanchez 2013-02-15 Human molecular genetics
35579944 A Direct Assay for Measuring the Activity and Inhibition of Coactivator-Associated Arginine Methyltransferase 1. Yurui Zhang 2022-05-17 Biochemistry
28115626 PRMT5 regulates IRES-dependent translation via methylation of hnRNP A1. Guozhen Gao 2017-05-05 Nucleic acids research
26789238 Small Molecule Inhibitors of Protein Arginine Methyltransferases. Hao Hu 2016-01-01 Expert opinion on investigational drugs
29894694 CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis. M Sarah Greenblatt 2018-06-11 Cancer cell
28637181 Crosstalk between histone modifications indicates that inhibition of arginine methyltransferase CARM1 activity reverses HIV latency. Zheng Zhang 2017-09-19 Nucleic acids research
31101937 Cellular consequences of arginine methylation. M Benjamin Lorton 2019-08-01 Cellular and molecular life sciences : CMLS
21478268 A coactivator role of CARM1 in the dysregulation of β-catenin activity in colorectal cancer cell growth and gene expression. Chen-Yin Ou 2011-05-01 Molecular cancer research : MCR
26656492 A novel role for CARM1 in promoting nonsense-mediated mRNA decay: potential implications for spinal muscular atrophy. Gabriel Sanchez 2016-04-07 Nucleic acids research
35246137 CARM1 promotes gastric cancer progression by regulating TFE3 mediated autophagy enhancement through the cytoplasmic AMPK-mTOR and nuclear AMPK-CARM1-TFE3 signaling pathways. Suzhen Yang 2022-03-04 Cancer cell international
35193797 The Mediator kinase module: an interface between cell signaling and transcription. Olivia Luyties 2022-04-01 Trends in biochemical sciences
23837869 Loss of CARM1 is linked to reduced HuR function in replicative senescence. Lijun Pang 2013-07-09 BMC molecular biology
35063035 Circular RNA circZNF532 facilitates angiogenesis and inflammation in diabetic retinopathy via regulating miR-1243/CARM1 axis. Ting Wang 2022-01-21 Diabetology & metabolic syndrome

Transcripts

Name Transcript ID bp Protein Translation ID
CARM1-201 ENST00000327064 3295 608aa ENSP00000325690
CARM1-211 ENST00000710361 3295 625aa ENSP00000518232
CARM1-206 ENST00000588947 468 120aa ENSP00000465417
CARM1-209 ENST00000590699 2240 161aa ENSP00000467420
CARM1-202 ENST00000344150 2722 585aa ENSP00000340934
CARM1-203 ENST00000586221 2766 343aa ENSP00000467746
CARM1-208 ENST00000590039 596 111aa ENSP00000464852
CARM1-207 ENST00000589693 601 92aa ENSP00000468319
CARM1-205 ENST00000586508 1050 No protein -
CARM1-204 ENST00000586298 674 176aa ENSP00000467761
CARM1-210 ENST00000592516 696 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
17344Cholesterol, LDL8.973e-00519060910
30468Eosinophils7.0470000E-005-
35062Platelet Function Tests1.8150100E-005-
75911C-Reactive Protein2E-827286809
75912Cholesterol, LDL2E-827286809
96638C-Reactive Protein3E-827286809
96639Cholesterol3E-827286809
97769S-(3-hydroxypropyl)cysteine N-acetate6E-726053186
97770Smoking6E-726053186

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000142453homo_sapiensENSP0000031439623.668612.071homo_sapiensENSP0000032569032.894716.7763
ENSG00000142453homo_sapiensENSP0000034790645.727528.8684homo_sapiensENSP0000032569032.565820.5592
ENSG00000142453homo_sapiensENSP0000040932425.144514.3064homo_sapiensENSP0000032569028.618416.2829
ENSG00000142453homo_sapiensENSP0000040616252.560632.8841homo_sapiensENSP0000032569032.072420.0658
ENSG00000142453homo_sapiensENSP0000037206750.507630.9645homo_sapiensENSP0000032569032.730320.0658
ENSG00000142453homo_sapiensENSP000003590954832.8homo_sapiensENSP0000032569029.605320.2303
ENSG00000142453homo_sapiensENSP0000033187941.619625.4237homo_sapiensENSP0000032569036.348722.2039

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000142453homo_sapiensENSP0000032569092.269792.1053nomascus_leucogenysENSNLEP0000001503799.644899.4671
ENSG00000142453homo_sapiensENSP0000032569091.118489.6382pan_paniscusENSPPAP0000001484888.076386.6455
ENSG00000142453homo_sapiensENSP0000032569099.506699.3421pongo_abeliiENSPPYP0000001072899.506699.3421
ENSG00000142453homo_sapiensENSP0000032569010099.8355pan_troglodytesENSPTRP0000004127210099.8355
ENSG00000142453homo_sapiensENSP0000032569093.585593.4211gorilla_gorillaENSGGOP0000000068499.128998.9547
ENSG00000142453homo_sapiensENSP0000032569094.243492.7632ornithorhynchus_anatinusENSOANP0000005214393.780792.3077
ENSG00000142453homo_sapiensENSP0000032569094.243493.0921sarcophilus_harrisiiENSSHAP0000003047794.398793.2455
ENSG00000142453homo_sapiensENSP0000032569064.802664.1447notamacropus_eugeniiENSMEUP0000000312574.060273.3083
ENSG00000142453homo_sapiensENSP0000032569083.223778.4539dasypus_novemcinctusENSDNOP0000002607562.469158.8889
ENSG00000142453homo_sapiensENSP0000032569049.506642.2697echinops_telfairiENSETEP0000001142673.594162.8362
ENSG00000142453homo_sapiensENSP0000032569063.486862.1711echinops_telfairiENSETEP0000000437573.946472.4138
ENSG00000142453homo_sapiensENSP0000032569098.684298.3553callithrix_jacchusENSCJAP0000001153798.522298.1938
ENSG00000142453homo_sapiensENSP0000032569098.848798.6842cercocebus_atysENSCATP0000002226090.922890.7716
ENSG00000142453homo_sapiensENSP0000032569087.828985.1974macaca_fascicularisENSMFAP0000003167987.112684.5024
ENSG00000142453homo_sapiensENSP0000032569099.671199.5066macaca_mulattaENSMMUP0000006515999.671199.5066
ENSG00000142453homo_sapiensENSP0000032569092.434290.625macaca_nemestrinaENSMNEP0000001475291.980490.18
ENSG00000142453homo_sapiensENSP0000032569091.282989.4737papio_anubisENSPANP0000000744293.7591.8919
ENSG00000142453homo_sapiensENSP0000032569087.664587.6645mandrillus_leucophaeusENSMLEP0000000163999.812799.8127
ENSG00000142453homo_sapiensENSP0000032569088.815888.1579tursiops_truncatusENSTTRP0000001578088.815888.1579
ENSG00000142453homo_sapiensENSP0000032569074.506671.3816vulpes_vulpesENSVVUP0000002430658.226255.7841
ENSG00000142453homo_sapiensENSP0000032569098.684297.6974mus_spretusMGP_SPRETEiJ_P009053198.684297.6974
ENSG00000142453homo_sapiensENSP0000032569098.355397.6974equus_asinusENSEASP0000501065598.355397.6974
ENSG00000142453homo_sapiensENSP0000032569097.697496.875capra_hircusENSCHIP0000000435097.697496.875
ENSG00000142453homo_sapiensENSP0000032569087.335587.0066loxodonta_africanaENSLAFP0000000369992.187591.8403
ENSG00000142453homo_sapiensENSP0000032569098.848798.0263panthera_leoENSPLOP0000000592698.848798.0263
ENSG00000142453homo_sapiensENSP0000032569088.651387.1711ailuropoda_melanoleucaENSAMEP0000001160396.942495.3237
ENSG00000142453homo_sapiensENSP0000032569097.697496.7105bos_indicus_hybridENSBIXP0000502537997.697496.7105
ENSG00000142453homo_sapiensENSP0000032569078.289575.1645oryctolagus_cuniculusENSOCUP0000002385185.611582.1942
ENSG00000142453homo_sapiensENSP0000032569098.355397.6974equus_caballusENSECAP0000004849998.355397.6974
ENSG00000142453homo_sapiensENSP0000032569024.506623.3553canis_lupus_familiarisENSCAFP0084502612486.627982.5581
ENSG00000142453homo_sapiensENSP0000032569098.848798.0263canis_lupus_familiarisENSCAFP0084503158898.848798.0263
ENSG00000142453homo_sapiensENSP0000032569087.171186.6776panthera_pardusENSPPRP0000001468387.171186.6776
ENSG00000142453homo_sapiensENSP0000032569087.828987.1711marmota_marmota_marmotaENSMMMP0000002254296.564295.8409
ENSG00000142453homo_sapiensENSP0000032569086.513284.5395balaenoptera_musculusENSBMSP0001001506686.088484.1244
ENSG00000142453homo_sapiensENSP0000032569090.953989.1447cavia_porcellusENSCPOP0000002372386.271584.5554
ENSG00000142453homo_sapiensENSP0000032569098.848798.0263felis_catusENSFCAP0000000452398.848798.0263
ENSG00000142453homo_sapiensENSP0000032569091.940889.9671ursus_americanusENSUAMP0000000750087.893186.0063
ENSG00000142453homo_sapiensENSP0000032569086.019784.8684monodelphis_domesticaENSMODP0000003370493.226491.9786
ENSG00000142453homo_sapiensENSP0000032569087.171186.1842bison_bison_bisonENSBBBP0000002249986.4685.4812
ENSG00000142453homo_sapiensENSP0000032569097.861897.0395monodon_monocerosENSMMNP0001500195997.54196.7213
ENSG00000142453homo_sapiensENSP0000032569090.953988.6513sus_scrofaENSSSCP0000006839086.003183.8258
ENSG00000142453homo_sapiensENSP0000032569094.901394.2434microcebus_murinusENSMICP0000001716599.140998.4536
ENSG00000142453homo_sapiensENSP0000032569085.197483.7171octodon_degusENSODEP0000002168187.945786.4177
ENSG00000142453homo_sapiensENSP0000032569096.710595.3947jaculus_jaculusENSJJAP0000000398993.481792.2099
ENSG00000142453homo_sapiensENSP0000032569097.697496.7105ovis_aries_rambouilletENSOARP0002000920297.697496.7105
ENSG00000142453homo_sapiensENSP0000032569082.894781.7434ursus_maritimusENSUMAP0000003470495.094393.7736
ENSG00000142453homo_sapiensENSP0000032569097.861897.0395delphinapterus_leucasENSDLEP0000003051097.54196.7213
ENSG00000142453homo_sapiensENSP0000032569097.861897.0395physeter_catodonENSPCTP0000501924397.54196.7213
ENSG00000142453homo_sapiensENSP0000032569098.684297.6974mus_caroliMGP_CAROLIEiJ_P008697498.684297.6974
ENSG00000142453homo_sapiensENSP0000032569098.684297.6974mus_musculusENSMUSP0000011105292.165991.2442
ENSG00000142453homo_sapiensENSP0000032569085.032982.7303dipodomys_ordiiENSDORP0000001918090.069787.6307
ENSG00000142453homo_sapiensENSP0000032569087.006686.5132mustela_putorius_furoENSMPUP0000000570594.973194.4345
ENSG00000142453homo_sapiensENSP0000032569097.861897.3684aotus_nancymaaeENSANAP0000001886697.861897.3684
ENSG00000142453homo_sapiensENSP0000032569087.587.1711saimiri_boliviensis_boliviensisENSSBOP0000003120198.15597.786
ENSG00000142453homo_sapiensENSP0000032569098.190898.0263chlorocebus_sabaeusENSCSAP0000000319998.029697.8654
ENSG00000142453homo_sapiensENSP0000032569093.421191.9408mesocricetus_auratusENSMAUP0000002324688.473587.0716
ENSG00000142453homo_sapiensENSP0000032569097.861897.0395phocoena_sinusENSPSNP0000000092497.381396.563
ENSG00000142453homo_sapiensENSP0000032569090.131688.9803camelus_dromedariusENSCDRP0000501428985.893484.7962
ENSG00000142453homo_sapiensENSP0000032569089.144787.6645carlito_syrichtaENSTSYP0000002714293.448391.8966
ENSG00000142453homo_sapiensENSP0000032569073.684271.875panthera_tigris_altaicaENSPTIP0000002459688.712986.5347
ENSG00000142453homo_sapiensENSP0000032569098.684297.6974rattus_norvegicusENSRNOP0000004942892.165991.2442
ENSG00000142453homo_sapiensENSP0000032569090.296188.6513prolemur_simusENSPSMP0000002496290.147888.5057
ENSG00000142453homo_sapiensENSP0000032569094.407992.9276microtus_ochrogasterENSMOCP0000000488489.968788.558
ENSG00000142453homo_sapiensENSP0000032569087.006686.1842peromyscus_maniculatus_bairdiiENSPEMP0000002749581.259680.4916
ENSG00000142453homo_sapiensENSP0000032569088.322486.8421bos_mutusENSBMUP0000000468787.459385.9935
ENSG00000142453homo_sapiensENSP0000032569098.684297.6974mus_spicilegusENSMSIP0000001853698.684297.6974
ENSG00000142453homo_sapiensENSP0000032569098.355397.3684cricetulus_griseus_chok1gshdENSCGRP0000102569491.858790.937
ENSG00000142453homo_sapiensENSP0000032569085.855384.5395pteropus_vampyrusENSPVAP0000001146285.996784.6787
ENSG00000142453homo_sapiensENSP0000032569087.335586.1842myotis_lucifugusENSMLUP0000001009992.994791.7688
ENSG00000142453homo_sapiensENSP0000032569020.888219.0789vombatus_ursinusENSVURP0001002078379.874272.956
ENSG00000142453homo_sapiensENSP0000032569031.578929.4408vombatus_ursinusENSVURP0001002079584.210578.5088
ENSG00000142453homo_sapiensENSP0000032569031.578929.4408vombatus_ursinusENSVURP0001002862784.210578.5088
ENSG00000142453homo_sapiensENSP0000032569020.888219.0789vombatus_ursinusENSVURP0001002862479.874272.956
ENSG00000142453homo_sapiensENSP0000032569095.065893.9145vombatus_ursinusENSVURP0001000748095.222494.0692
ENSG00000142453homo_sapiensENSP0000032569097.532996.875rhinolophus_ferrumequinumENSRFEP0001001988397.372796.7159
ENSG00000142453homo_sapiensENSP0000032569087.171186.6776neovison_visonENSNVIP0000000106087.171186.6776
ENSG00000142453homo_sapiensENSP0000032569088.980386.5132bos_taurusENSBTAP0000005734283.230880.9231
ENSG00000142453homo_sapiensENSP0000032569098.190897.0395heterocephalus_glaber_femaleENSHGLP0000001080397.868996.7213
ENSG00000142453homo_sapiensENSP0000032569090.460588.9803rhinopithecus_bietiENSRBIP0000001073994.501792.9553
ENSG00000142453homo_sapiensENSP0000032569098.519797.5329canis_lupus_dingoENSCAFP0002003143095.686994.7284
ENSG00000142453homo_sapiensENSP0000032569025.822425canis_lupus_dingoENSCAFP0002003476388.700685.8757
ENSG00000142453homo_sapiensENSP0000032569099.013298.1908sciurus_vulgarisENSSVLP0000502825699.013298.1908
ENSG00000142453homo_sapiensENSP0000032569092.927691.7763phascolarctos_cinereusENSPCIP0000004855287.461386.3777
ENSG00000142453homo_sapiensENSP0000032569020.559218.5855phascolarctos_cinereusENSPCIP0000004610676.687169.3252
ENSG00000142453homo_sapiensENSP0000032569058.223758.0592procavia_capensisENSPCAP0000000092266.292166.1049
ENSG00000142453homo_sapiensENSP0000032569095.888295.0658nannospalax_galiliENSNGAP0000000186495.888295.0658
ENSG00000142453homo_sapiensENSP0000032569097.697496.7105bos_grunniensENSBGRP0000000863297.697496.7105
ENSG00000142453homo_sapiensENSP0000032569087.006686.8421chinchilla_lanigeraENSCLAP0000001599798.878598.6916
ENSG00000142453homo_sapiensENSP0000032569095.888294.9013cervus_hanglu_yarkandensisENSCHYP0000000458795.888294.9013
ENSG00000142453homo_sapiensENSP0000032569098.355397.0395catagonus_wagneriENSCWAP0000002584198.355397.0395
ENSG00000142453homo_sapiensENSP0000032569090.460588.4868ictidomys_tridecemlineatusENSSTOP0000002678991.973289.9666
ENSG00000142453homo_sapiensENSP0000032569088.157987.6645otolemur_garnettiiENSOGAP0000001507392.733692.2145
ENSG00000142453homo_sapiensENSP0000032569098.848798.3553cebus_imitatorENSCCAP0000000593998.686498.1938
ENSG00000142453homo_sapiensENSP0000032569099.506698.6842urocitellus_parryiiENSUPAP0001000386999.343298.5222
ENSG00000142453homo_sapiensENSP0000032569097.697496.5461moschus_moschiferusENSMMSP0000000094597.697496.5461
ENSG00000142453homo_sapiensENSP0000032569089.638288.6513rhinopithecus_roxellanaENSRROP0000001978196.631295.5674
ENSG00000142453homo_sapiensENSP0000032569098.684297.6974mus_pahariMGP_PahariEiJ_P002262498.684297.6974
ENSG00000142453homo_sapiensENSP0000032569087.828987.5propithecus_coquereliENSPCOP0000001447396.739196.3768
ENSG00000142453homo_sapiensENSP0000032569059.703947.2039drosophila_melanogasterFBpp030584068.490654.1509
ENSG00000142453homo_sapiensENSP0000032569028.782917.4342drosophila_melanogasterFBpp031176949.295829.8592
ENSG00000142453homo_sapiensENSP0000032569058.552646.875ciona_intestinalisENSCINP0000002283777.223461.8221
ENSG00000142453homo_sapiensENSP0000032569080.263268.5855petromyzon_marinusENSPMAP0000000409979.738668.1373
ENSG00000142453homo_sapiensENSP0000032569074.342164.4737eptatretus_burgeriENSEBUP0000002527868.381259.3041
ENSG00000142453homo_sapiensENSP0000032569084.868478.125callorhinchus_miliiENSCMIP0000000108782.958276.3666
ENSG00000142453homo_sapiensENSP0000032569081.414575.4934latimeria_chalumnaeENSLACP0000001782188.392981.9643
ENSG00000142453homo_sapiensENSP0000032569086.842180.4276lepisosteus_oculatusENSLOCP0000000734090.41183.7329
ENSG00000142453homo_sapiensENSP0000032569083.717174.6711clupea_harengusENSCHAP0000000892083.717174.6711
ENSG00000142453homo_sapiensENSP0000032569087.171179.7697clupea_harengusENSCHAP0000000742186.03978.7338
ENSG00000142453homo_sapiensENSP0000032569088.322481.7434danio_rerioENSDARP0000001695991.326584.5238
ENSG00000142453homo_sapiensENSP0000032569079.769773.1908carassius_auratusENSCARP0000011480688.827881.5018
ENSG00000142453homo_sapiensENSP0000032569089.144781.7434carassius_auratusENSCARP0000002233189.883982.4212
ENSG00000142453homo_sapiensENSP0000032569088.486881.7434carassius_auratusENSCARP0000004557288.925682.1488
ENSG00000142453homo_sapiensENSP0000032569081.414575.4934astyanax_mexicanusENSAMXP0000001907991.328484.6863
ENSG00000142453homo_sapiensENSP0000032569088.651382.0724ictalurus_punctatusENSIPUP0000000143091.822885.0085
ENSG00000142453homo_sapiensENSP0000032569083.223776.1513esox_luciusENSELUP0000003657085.04277.8151
ENSG00000142453homo_sapiensENSP0000032569078.12570.0658esox_luciusENSELUP0000007390075.039567.2986
ENSG00000142453homo_sapiensENSP0000032569085.690878.7829electrophorus_electricusENSEEEP0000000871086.258379.3046
ENSG00000142453homo_sapiensENSP0000032569086.513279.7697oncorhynchus_kisutchENSOKIP0000509616887.375480.5648
ENSG00000142453homo_sapiensENSP0000032569088.980382.5658oncorhynchus_kisutchENSOKIP0000508434189.569583.1126
ENSG00000142453homo_sapiensENSP0000032569078.453968.0921oncorhynchus_kisutchENSOKIP0000507441146.042539.9614
ENSG00000142453homo_sapiensENSP0000032569086.184277.7961oncorhynchus_kisutchENSOKIP0000511392687.18878.7022
ENSG00000142453homo_sapiensENSP0000032569088.322482.0724oncorhynchus_mykissENSOMYP0000002924589.949783.5846
ENSG00000142453homo_sapiensENSP0000032569085.526377.3026oncorhynchus_mykissENSOMYP0000010902287.986579.5262
ENSG00000142453homo_sapiensENSP0000032569088.322482.0724oncorhynchus_mykissENSOMYP0000013928488.907382.6159
ENSG00000142453homo_sapiensENSP0000032569079.276369.4079oncorhynchus_mykissENSOMYP0000013781225.720422.5187
ENSG00000142453homo_sapiensENSP0000032569088.322481.9079salmo_salarENSSSAP0000000308585.9279.68
ENSG00000142453homo_sapiensENSP0000032569088.157982.0724salmo_salarENSSSAP0000000306585.897479.9679
ENSG00000142453homo_sapiensENSP0000032569085.361876.9737salmo_salarENSSSAP0000017650289.328780.5508
ENSG00000142453homo_sapiensENSP0000032569088.322481.9079salmo_truttaENSSTUP0000002507084.169378.0564
ENSG00000142453homo_sapiensENSP0000032569082.236876.3158salmo_truttaENSSTUP0000010847784.31778.2462
ENSG00000142453homo_sapiensENSP0000032569084.703975.9868salmo_truttaENSSTUP0000007509685.548276.7442
ENSG00000142453homo_sapiensENSP0000032569088.322482.0724salmo_truttaENSSTUP0000010727685.9279.84
ENSG00000142453homo_sapiensENSP0000032569086.184277.6316salmo_truttaENSSTUP0000001519587.18878.5358
ENSG00000142453homo_sapiensENSP0000032569087.828980.7566gadus_morhuaENSGMOP0000005276682.919376.2422
ENSG00000142453homo_sapiensENSP0000032569086.677680.2632fundulus_heteroclitusENSFHEP0000002190389.32282.7119
ENSG00000142453homo_sapiensENSP0000032569087.664581.25poecilia_reticulataENSPREP0000001096491.580884.8797
ENSG00000142453homo_sapiensENSP0000032569088.651382.0724xiphophorus_maculatusENSXMAP0000002469488.943982.3432
ENSG00000142453homo_sapiensENSP0000032569087.580.2632oryzias_latipesENSORLP0000003238591.566383.9931
ENSG00000142453homo_sapiensENSP0000032569087.828981.0855cyclopterus_lumpusENSCLMP0000500823388.704381.8937
ENSG00000142453homo_sapiensENSP0000032569087.581.5789oreochromis_niloticusENSONIP0000000788687.933981.9835
ENSG00000142453homo_sapiensENSP0000032569087.335581.4145haplochromis_burtoniENSHBUP0000002654191.394185.1979
ENSG00000142453homo_sapiensENSP0000032569085.032978.4539astatotilapia_callipteraENSACLP0000000693373.857168.1429
ENSG00000142453homo_sapiensENSP0000032569088.322482.2368sparus_aurataENSSAUP0001001314484.834178.9889
ENSG00000142453homo_sapiensENSP0000032569083.552677.1382lates_calcariferENSLCAP0001003209687.285280.5842
ENSG00000142453homo_sapiensENSP0000032569088.815883.3882xenopus_tropicalisENSXETP0000002062589.70184.2193
ENSG00000142453homo_sapiensENSP0000032569087.006684.2105chrysemys_picta_belliiENSCPBP0000001367487.873885.0498
ENSG00000142453homo_sapiensENSP0000032569086.677683.5526sphenodon_punctatusENSSPUP0000000585994.61491.2029
ENSG00000142453homo_sapiensENSP0000032569057.236851.9737laticauda_laticaudataENSLLTP0000000662880.930273.4884
ENSG00000142453homo_sapiensENSP0000032569091.282988.3224notechis_scutatusENSNSUP0000002708392.964889.9497
ENSG00000142453homo_sapiensENSP0000032569077.796174.0132pseudonaja_textilisENSPTXP0000002155794.035889.4632
ENSG00000142453homo_sapiensENSP0000032569091.611889.1447anolis_carolinensisENSACAP0000003925895.704593.1272
ENSG00000142453homo_sapiensENSP0000032569018.7515.9539neolamprologus_brichardiENSNBRP0000001119777.55165.9864
ENSG00000142453homo_sapiensENSP0000032569092.269789.4737naja_najaENSNNAP0000002752796.226493.3105
ENSG00000142453homo_sapiensENSP0000032569093.421190.9539podarcis_muralisENSPMRP0000003441979.329677.2346
ENSG00000142453homo_sapiensENSP0000032569092.927690.9539taeniopygia_guttataENSTGUP0000002674866.470665.0588
ENSG00000142453homo_sapiensENSP0000032569091.776389.9671taeniopygia_guttataENSTGUP0000002904096.041394.148
ENSG00000142453homo_sapiensENSP0000032569089.473784.2105erpetoichthys_calabaricusENSECRP0000002476090.515885.1913
ENSG00000142453homo_sapiensENSP0000032569087.828982.0724kryptolebias_marmoratusENSKMAP0000002781791.910585.8864
ENSG00000142453homo_sapiensENSP0000032569092.598790.1316salvator_merianaeENSSMRP0000000571386.748884.4376
ENSG00000142453homo_sapiensENSP0000032569088.486882.2368amphilophus_citrinellusENSACIP0000001757985.126679.1139
ENSG00000142453homo_sapiensENSP0000032569081.578975.1645dicentrarchus_labraxENSDLAP0000506033274.924569.0332
ENSG00000142453homo_sapiensENSP0000032569087.664581.5789amphiprion_perculaENSAPEP0000002976287.664581.5789
ENSG00000142453homo_sapiensENSP0000032569019.407916.4474oryzias_sinensisENSOSIP0000004822671.951260.9756
ENSG00000142453homo_sapiensENSP0000032569057.894753.2895oryzias_sinensisENSOSIP0000002736583.809577.1429
ENSG00000142453homo_sapiensENSP0000032569092.598790.1316gopherus_evgoodeiENSGEVP0000501816696.569593.9966
ENSG00000142453homo_sapiensENSP0000032569087.006684.2105chelonoidis_abingdoniiENSCABP0000000579493.298190.2998
ENSG00000142453homo_sapiensENSP0000032569087.664581.4145seriola_dumeriliENSSDUP0000003250991.738485.1979
ENSG00000142453homo_sapiensENSP0000032569087.006680.7566gasterosteus_aculeatusENSGACP0000000734690.119283.6457
ENSG00000142453homo_sapiensENSP0000032569082.894776.4803cynoglossus_semilaevisENSCSEP0000002161490.322683.3333
ENSG00000142453homo_sapiensENSP0000032569088.651381.7434poecilia_formosaENSPFOP0000001969286.516979.7753
ENSG00000142453homo_sapiensENSP0000032569088.980382.4013myripristis_murdjanENSMMDP0000501323880.148174.2222
ENSG00000142453homo_sapiensENSP0000032569088.486882.0724sander_luciopercaENSSLUP0000003587188.196781.8033
ENSG00000142453homo_sapiensENSP0000032569088.651382.5658amphiprion_ocellarisENSAOCP0000001935689.683983.5275
ENSG00000142453homo_sapiensENSP0000032569088.322485.8553terrapene_carolina_triunguisENSTMTP0000003099492.906690.3114
ENSG00000142453homo_sapiensENSP0000032569065.789560.0329hucho_huchoENSHHUP0000008784390.909182.9545
ENSG00000142453homo_sapiensENSP0000032569017.598715.1316hucho_huchoENSHHUP0000002850682.307770.7692
ENSG00000142453homo_sapiensENSP0000032569088.157981.9079hucho_huchoENSHHUP0000002778689.036582.7243
ENSG00000142453homo_sapiensENSP0000032569073.848765.625hucho_huchoENSHHUP0000005842183.925274.5794
ENSG00000142453homo_sapiensENSP0000032569020.559216.7763hucho_huchoENSHHUP0000001230770.621557.6271
ENSG00000142453homo_sapiensENSP0000032569087.006680.5921betta_splendensENSBSLP0000000585290.119283.4753
ENSG00000142453homo_sapiensENSP0000032569087.171180.7566pygocentrus_nattereriENSPNAP0000003435790.443783.7884
ENSG00000142453homo_sapiensENSP0000032569083.881676.3158anabas_testudineusENSATEP0000003840082.926875.4472
ENSG00000142453homo_sapiensENSP0000032569056.2545.0658ciona_savignyiENSCSAVP0000001132375.663760.6195
ENSG00000142453homo_sapiensENSP0000032569029.769719.5724saccharomyces_cerevisiaeYBR034C52.011534.1954
ENSG00000142453homo_sapiensENSP0000032569087.664581.0855seriola_lalandi_dorsalisENSSLDP0000001421591.738484.8537
ENSG00000142453homo_sapiensENSP0000032569087.664580.5921labrus_bergyltaENSLBEP0000001312391.738484.3373
ENSG00000142453homo_sapiensENSP0000032569087.335581.4145pundamilia_nyerereiENSPNYP0000002985591.394185.1979
ENSG00000142453homo_sapiensENSP0000032569083.552676.1513mastacembelus_armatusENSMAMP0000005728775.036968.39
ENSG00000142453homo_sapiensENSP0000032569088.980382.7303stegastes_partitusENSSPAP0000001171689.273983.0033
ENSG00000142453homo_sapiensENSP0000032569072.039565.625oncorhynchus_tshawytschaENSOTSP0000509957086.732779.0099
ENSG00000142453homo_sapiensENSP0000032569075.493468.2566oncorhynchus_tshawytschaENSOTSP0000502994784.842976.7098
ENSG00000142453homo_sapiensENSP0000032569087.581.5789acanthochromis_polyacanthusENSAPOP0000001488991.566385.37
ENSG00000142453homo_sapiensENSP0000032569092.434291.2829aquila_chrysaetos_chrysaetosENSACCP0002000304096.729895.525
ENSG00000142453homo_sapiensENSP0000032569088.651381.7434nothobranchius_furzeriENSNFUP0001501217289.090982.1488
ENSG00000142453homo_sapiensENSP0000032569087.828981.5789cyprinodon_variegatusENSCVAP000000252778982.6667
ENSG00000142453homo_sapiensENSP0000032569084.046174.0132denticeps_clupeoidesENSDCDP0000000157587.201476.7918
ENSG00000142453homo_sapiensENSP0000032569083.388274.6711denticeps_clupeoidesENSDCDP0000000615242.569338.1192
ENSG00000142453homo_sapiensENSP0000032569088.157981.9079larimichthys_croceaENSLCRP0000501336989.184782.8619
ENSG00000142453homo_sapiensENSP0000032569085.197477.4671takifugu_rubripesENSTRUP0000005017883.413875.8454
ENSG00000142453homo_sapiensENSP0000032569023.848718.9145ficedula_albicollisENSFALP0000000965832.954526.1364
ENSG00000142453homo_sapiensENSP0000032569083.223776.9737hippocampus_comesENSHCOP0000000597588.927982.2496
ENSG00000142453homo_sapiensENSP0000032569088.322481.7434cyprinus_carpio_carpioENSCCRP0000005553785.782779.393
ENSG00000142453homo_sapiensENSP0000032569088.815881.7434cyprinus_carpio_carpioENSCCRP0000005515586.677479.7753
ENSG00000142453homo_sapiensENSP0000032569087.828981.4145poecilia_latipinnaENSPLAP0000000920991.910585.1979
ENSG00000142453homo_sapiensENSP0000032569087.664581.0855sinocyclocheilus_grahamiENSSGRP0000010973388.099281.4876
ENSG00000142453homo_sapiensENSP0000032569079.934273.5197sinocyclocheilus_grahamiENSSGRP0000006298285.113878.2837
ENSG00000142453homo_sapiensENSP0000032569087.335581.4145maylandia_zebraENSMZEP0000500051991.394185.1979
ENSG00000142453homo_sapiensENSP0000032569086.019779.9342tetraodon_nigroviridisENSTNIP0000001701690.328283.9378
ENSG00000142453homo_sapiensENSP0000032569087.335580.9211paramormyrops_kingsleyaeENSPKIP0000002049391.237184.5361
ENSG00000142453homo_sapiensENSP0000032569086.677681.0855paramormyrops_kingsleyaeENSPKIP0000001793987.251781.6225
ENSG00000142453homo_sapiensENSP0000032569089.473783.5526scleropages_formosusENSSFOP000150457568579.375
ENSG00000142453homo_sapiensENSP0000032569088.815882.2368scleropages_formosusENSSFOP0001501592179.528773.6377
ENSG00000142453homo_sapiensENSP0000032569086.677679.7697scleropages_formosusENSSFOP0001505606386.535379.6388
ENSG00000142453homo_sapiensENSP0000032569086.513280.5921leptobrachium_leishanenseENSLLEP0000002523489.761183.6177
ENSG00000142453homo_sapiensENSP0000032569089.638283.3882leptobrachium_leishanenseENSLLEP0000000535988.762282.5733
ENSG00000142453homo_sapiensENSP0000032569087.335580.7566scophthalmus_maximusENSSMAP0000004695288.059781.4262
ENSG00000142453homo_sapiensENSP0000032569052.467148.6842oryzias_melastigmaENSOMEP0000002994993.823587.0588
ENSG00000142453homo_sapiensENSP0000032569032.894729.7697oryzias_melastigmaENSOMEP0000002992881.632773.8775

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000976enables transcription cis-regulatory region binding1ISSHomo_sapiens(9606)Function
GO:0003713enables transcription coactivator activity2IDA,ISSHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus1IDAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm1IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol2IDA,ISSHomo_sapiens(9606)Component
GO:0006338involved_in chromatin remodeling1IEAHomo_sapiens(9606)Process
GO:0006355involved_in regulation of DNA-templated transcription1ISSHomo_sapiens(9606)Process
GO:0008013enables beta-catenin binding1TASHomo_sapiens(9606)Function
GO:0008276enables protein methyltransferase activity2IDA,ISSHomo_sapiens(9606)Function
GO:0008284involved_in positive regulation of cell population proliferation1IEAHomo_sapiens(9606)Process
GO:0008469enables histone arginine N-methyltransferase activity1IDAHomo_sapiens(9606)Function
GO:0016274enables protein-arginine N-methyltransferase activity3IDA,ISS,TASHomo_sapiens(9606)Function
GO:0016571involved_in histone methylation1ISSHomo_sapiens(9606)Process
GO:0018216involved_in peptidyl-arginine methylation1IEAHomo_sapiens(9606)Process
GO:0030374enables nuclear receptor coactivator activity1ISSHomo_sapiens(9606)Function
GO:0033146involved_in regulation of intracellular estrogen receptor signaling pathway1ISSHomo_sapiens(9606)Process
GO:0035242enables protein-arginine omega-N asymmetric methyltransferase activity1ISSHomo_sapiens(9606)Function
GO:0035642enables histone H3R17 methyltransferase activity2IDA,ISSHomo_sapiens(9606)Function
GO:0042054enables histone methyltransferase activity1IDAHomo_sapiens(9606)Function
GO:0043596is_active_in nuclear replication fork1IDAHomo_sapiens(9606)Component
GO:0045600involved_in positive regulation of fat cell differentiation1ISSHomo_sapiens(9606)Process
GO:0045943involved_in positive regulation of transcription by RNA polymerase I1IDAHomo_sapiens(9606)Process
GO:0051591involved_in response to cAMP1IEAHomo_sapiens(9606)Process
GO:0070577enables lysine-acetylated histone binding1ISSHomo_sapiens(9606)Function
GO:0070611enables histone H3R2 methyltransferase activity2IMP,ISSHomo_sapiens(9606)Function
GO:0071932involved_in replication fork reversal1IDAHomo_sapiens(9606)Process
GO:0140297enables DNA-binding transcription factor binding1IPIHomo_sapiens(9606)Function
GO:1902415involved_in regulation of mRNA binding1IEAHomo_sapiens(9606)Process
GO:1904037involved_in positive regulation of epithelial cell apoptotic process1IDAHomo_sapiens(9606)Process
GO:2000171involved_in negative regulation of dendrite development1IEAHomo_sapiens(9606)Process

Expression