Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions N.A.
Localizations Stress granucleNucleoliNucleoli rim
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000141664 Gene ID 54877 Accession 22916
Symbol ZCCHC2 Alias C18orf49 Full Name zinc finger CCHC-type containing 2
Status Confidence Length 64685 bases Strand Plus strand
Position 18 : 62523025 - 62587709 RNA binding domain zf-CCHC
Summary Predicted to enable nucleic acid binding activity; phosphatidylinositol binding activity; and zinc ion binding activity. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000468368 zf-CCHC PF00098 2.5e-06 1
ENSP00000464791 zf-CCHC PF00098 1.8e-05 1
ENSP00000269499 zf-CCHC PF00098 2.3e-05 1
ENSP00000468789 zf-CCHC PF00098 2.5e-05 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
ZCCHC2-201 ENST00000269499 5937 1178aa ENSP00000269499
ZCCHC2-206 ENST00000588676 1877 378aa ENSP00000465548
ZCCHC2-202 ENST00000585873 5652 1098aa ENSP00000468789
ZCCHC2-210 ENST00000591632 608 No protein -
ZCCHC2-211 ENST00000621048 704 195aa ENSP00000480901
ZCCHC2-204 ENST00000586834 4765 857aa ENSP00000464791
ZCCHC2-209 ENST00000591435 455 No protein -
ZCCHC2-203 ENST00000585949 2429 No protein -
ZCCHC2-205 ENST00000587612 353 No protein -
ZCCHC2-208 ENST00000591145 673 106aa ENSP00000468368
ZCCHC2-207 ENST00000590840 2376 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
7422Dehydroepiandrosterone1.87985002822317E-717903292
11537Neuropsychological Tests2.14644570822773E-717903297
11580Mental Competency9.9710275533351E-917903295
15211Heart Failure5.0353898E-004-
59097Pulmonary Disease, Chronic Obstructive1.3970000E-00522837378
90954Longevity8E-627015805
94966Breast Feeding1E-625475840
106252Circadian Rhythm3E-626835600

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000141664homo_sapiensENSP0000049962240.515727.9926homo_sapiensENSP0000026949937.351425.8065

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000141664homo_sapiensENSP0000026949972.665572.326nomascus_leucogenysENSNLEP0000001053599.883399.4166
ENSG00000141664homo_sapiensENSP0000026949992.529792.275pan_paniscusENSPPAP0000001166899.816899.5421
ENSG00000141664homo_sapiensENSP0000026949999.405899.1511pongo_abeliiENSPPYP0000001033699.490299.2353
ENSG00000141664homo_sapiensENSP0000026949999.830299.8302pan_troglodytesENSPTRP0000001711899.91599.915
ENSG00000141664homo_sapiensENSP0000026949992.27592.0204gorilla_gorillaENSGGOP0000000291899.269498.9954
ENSG00000141664homo_sapiensENSP0000026949975.466967.5722ornithorhynchus_anatinusENSOANP0000005323078.119569.9473
ENSG00000141664homo_sapiensENSP0000026949988.115480.8998sarcophilus_harrisiiENSSHAP0000001900885.998378.9561
ENSG00000141664homo_sapiensENSP0000026949939.388835.0594notamacropus_eugeniiENSMEUP0000001419881.118972.2028
ENSG00000141664homo_sapiensENSP0000026949972.156268.9304choloepus_hoffmanniENSCHOP0000000209194.866190.625
ENSG00000141664homo_sapiensENSP0000026949988.285284.9745dasypus_novemcinctusENSDNOP0000001236995.06491.4991
ENSG00000141664homo_sapiensENSP0000026949960.01753.4805erinaceus_europaeusENSEEUP0000000799582.30573.3411
ENSG00000141664homo_sapiensENSP0000026949966.468661.7997echinops_telfairiENSETEP0000000225087.780381.6143
ENSG00000141664homo_sapiensENSP0000026949998.217397.6231callithrix_jacchusENSCJAP0000000603698.384497.7891
ENSG00000141664homo_sapiensENSP0000026949995.161394.7368cercocebus_atysENSCATP0000003060896.888596.4564
ENSG00000141664homo_sapiensENSP0000026949989.388889.0492macaca_fascicularisENSMFAP0000002056798.966298.5902
ENSG00000141664homo_sapiensENSP0000026949998.726798.3871macaca_mulattaENSMMUP0000000591298.642998.3036
ENSG00000141664homo_sapiensENSP0000026949995.925395.3311macaca_nemestrinaENSMNEP0000001946797.58296.9775
ENSG00000141664homo_sapiensENSP0000026949992.27591.9355papio_anubisENSPANP0000005660098.998298.6339
ENSG00000141664homo_sapiensENSP0000026949971.986471.6469mandrillus_leucophaeusENSMLEP0000001527098.949898.4831
ENSG00000141664homo_sapiensENSP0000026949965.534863.1579tursiops_truncatusENSTTRP0000001284193.689390.2913
ENSG00000141664homo_sapiensENSP0000026949985.908382.8523vulpes_vulpesENSVVUP0000002405194.934391.5572
ENSG00000141664homo_sapiensENSP0000026949990.407585.9932mus_spretusMGP_SPRETEiJ_P002038291.181586.7295
ENSG00000141664homo_sapiensENSP0000026949992.020489.3039equus_asinusENSEASP0000500342693.047290.3004
ENSG00000141664homo_sapiensENSP0000026949981.918575.1273capra_hircusENSCHIP0000001579685.777878.6667
ENSG00000141664homo_sapiensENSP0000026949988.964384.5501loxodonta_africanaENSLAFP0000001682192.661488.0637
ENSG00000141664homo_sapiensENSP0000026949993.03990.1528panthera_leoENSPLOP0000001994692.645889.7718
ENSG00000141664homo_sapiensENSP0000026949989.558686.927ailuropoda_melanoleucaENSAMEP0000000663495.82293.0064
ENSG00000141664homo_sapiensENSP0000026949982.088375.382bos_indicus_hybridENSBIXP0000501726386.493779.4276
ENSG00000141664homo_sapiensENSP0000026949968.421165.2801oryctolagus_cuniculusENSOCUP0000001043494.04989.7316
ENSG00000141664homo_sapiensENSP0000026949993.972891.4261equus_caballusENSECAP0000001270494.858692.2879
ENSG00000141664homo_sapiensENSP0000026949994.821791.7657canis_lupus_familiarisENSCAFP0084500001294.580991.5326
ENSG00000141664homo_sapiensENSP0000026949990.916888.2003panthera_pardusENSPPRP0000000386094.611391.7845
ENSG00000141664homo_sapiensENSP0000026949977.079874.7878marmota_marmota_marmotaENSMMMP0000000345096.698693.8232
ENSG00000141664homo_sapiensENSP0000026949995.41691.8506balaenoptera_musculusENSBMSP0001001718395.33591.7727
ENSG00000141664homo_sapiensENSP0000026949973.684270.6282cavia_porcellusENSCPOP0000001268792.340488.5106
ENSG00000141664homo_sapiensENSP0000026949995.585792.6995felis_catusENSFCAP0000001928295.181792.3077
ENSG00000141664homo_sapiensENSP0000026949991.341388.7097ursus_americanusENSUAMP0000002537293.973891.2664
ENSG00000141664homo_sapiensENSP0000026949987.521280.4754monodelphis_domesticaENSMODP0000000627886.13279.198
ENSG00000141664homo_sapiensENSP0000026949944.057740.2377bison_bison_bisonENSBBBP0000002610564.79459.176
ENSG00000141664homo_sapiensENSP0000026949995.246292.1053monodon_monocerosENSMMNP0001500655895.408292.2619
ENSG00000141664homo_sapiensENSP0000026949994.906691.7657sus_scrofaENSSSCP0000004055894.987391.8437
ENSG00000141664homo_sapiensENSP0000026949993.463591.0866microcebus_murinusENSMICP0000001952595.905993.4669
ENSG00000141664homo_sapiensENSP0000026949993.803191.0866octodon_degusENSODEP0000000711693.013590.3199
ENSG00000141664homo_sapiensENSP0000026949981.833676.0611jaculus_jaculusENSJJAP0000001119490.262283.8951
ENSG00000141664homo_sapiensENSP0000026949975.042472.1562ursus_maritimusENSUMAP0000000383590.573887.0902
ENSG00000141664homo_sapiensENSP0000026949965.704661.4601ochotona_princepsENSOPRP0000000780689.170583.4101
ENSG00000141664homo_sapiensENSP0000026949989.049286.0781delphinapterus_leucasENSDLEP0000000473395.974492.7722
ENSG00000141664homo_sapiensENSP0000026949994.906691.0866physeter_catodonENSPCTP0000501249294.906691.0866
ENSG00000141664homo_sapiensENSP0000026949990.916886.6723mus_caroliMGP_CAROLIEiJ_P001936091.460387.1904
ENSG00000141664homo_sapiensENSP0000026949990.407585.8234mus_musculusENSMUSP0000011397491.337986.7067
ENSG00000141664homo_sapiensENSP0000026949993.463590.2377dipodomys_ordiiENSDORP0000000958794.750491.4802
ENSG00000141664homo_sapiensENSP0000026949975.212271.3073mustela_putorius_furoENSMPUP0000001640788.684
ENSG00000141664homo_sapiensENSP0000026949994.312493.2937aotus_nancymaaeENSANAP0000003651495.61194.5783
ENSG00000141664homo_sapiensENSP0000026949987.096886.6723saimiri_boliviensis_boliviensisENSSBOP0000001219898.464597.9846
ENSG00000141664homo_sapiensENSP0000026949968.251365.4499vicugna_pacosENSVPAP0000000924593.163489.3395
ENSG00000141664homo_sapiensENSP0000026949990.237789.8132chlorocebus_sabaeusENSCSAP0000001420498.517198.0538
ENSG00000141664homo_sapiensENSP0000026949946.349744.652tupaia_belangeriENSTBEP0000001439063.414661.0918
ENSG00000141664homo_sapiensENSP0000026949985.314181.7487mesocricetus_auratusENSMAUP0000001755290.540586.7568
ENSG00000141664homo_sapiensENSP0000026949995.331192.1902phocoena_sinusENSPSNP0000002652195.412192.2685
ENSG00000141664homo_sapiensENSP0000026949968.590865.7046camelus_dromedariusENSCDRP0000502535694.613690.6323
ENSG00000141664homo_sapiensENSP0000026949970.203768.4211carlito_syrichtaENSTSYP0000000671096.499494.049
ENSG00000141664homo_sapiensENSP0000026949966.977964.601panthera_tigris_altaicaENSPTIP0000000723596.33792.9182
ENSG00000141664homo_sapiensENSP0000026949990.152885.3141rattus_norvegicusENSRNOP0000000387090.846985.9709
ENSG00000141664homo_sapiensENSP0000026949990.831989.3039prolemur_simusENSPSMP0000003162597.449995.8106
ENSG00000141664homo_sapiensENSP0000026949984.974580.9847microtus_ochrogasterENSMOCP0000002556087.347383.2461
ENSG00000141664homo_sapiensENSP0000026949984.719980.9847peromyscus_maniculatus_bairdiiENSPEMP0000001574386.332282.526
ENSG00000141664homo_sapiensENSP0000026949939.728436.6723bos_mutusENSBMUP0000002387158.354153.8653
ENSG00000141664homo_sapiensENSP0000026949985.39981.1545mus_spicilegusENSMSIP0000001676292.378387.787
ENSG00000141664homo_sapiensENSP0000026949991.426187.7759cricetulus_griseus_chok1gshdENSCGRP0000102403090.962887.3311
ENSG00000141664homo_sapiensENSP0000026949969.2764.2615pteropus_vampyrusENSPVAP0000001227591.173284.581
ENSG00000141664homo_sapiensENSP0000026949969.100265.1104myotis_lucifugusENSMLUP0000000865394.21388.7731
ENSG00000141664homo_sapiensENSP0000026949988.030681.0696vombatus_ursinusENSVURP0001001990286.416779.5833
ENSG00000141664homo_sapiensENSP0000026949991.341386.6723rhinolophus_ferrumequinumENSRFEP0001002029792.202287.4893
ENSG00000141664homo_sapiensENSP0000026949969.864266.8082neovison_visonENSNVIP0000001757269.864266.8082
ENSG00000141664homo_sapiensENSP0000026949981.918575.1273bos_taurusENSBTAP0000007013286.547179.3722
ENSG00000141664homo_sapiensENSP0000026949993.633391.0866heterocephalus_glaber_femaleENSHGLP0000000330394.596992.024
ENSG00000141664homo_sapiensENSP0000026949993.208892.6995rhinopithecus_bietiENSRBIP0000002377699.097598.556
ENSG00000141664homo_sapiensENSP0000026949992.359989.6435canis_lupus_dingoENSCAFP0002002158093.793191.0345
ENSG00000141664homo_sapiensENSP0000026949996.264993.8031sciurus_vulgarisENSSVLP0000500666496.264993.8031
ENSG00000141664homo_sapiensENSP0000026949986.332879.2869phascolarctos_cinereusENSPCIP0000001469685.390478.4215
ENSG00000141664homo_sapiensENSP0000026949970.543366.2988procavia_capensisENSPCAP0000000953392.53986.971
ENSG00000141664homo_sapiensENSP0000026949986.842184.8896nannospalax_galiliENSNGAP0000002398686.256384.317
ENSG00000141664homo_sapiensENSP0000026949977.164771.1375bos_grunniensENSBGRP0000002971583.089676.5996
ENSG00000141664homo_sapiensENSP0000026949971.052669.6095chinchilla_lanigeraENSCLAP0000001596297.099895.1276
ENSG00000141664homo_sapiensENSP0000026949968.251363.6672cervus_hanglu_yarkandensisENSCHYP0000002866686.637980.819
ENSG00000141664homo_sapiensENSP0000026949988.964385.399catagonus_wagneriENSCWAP0000001128295.533391.7047
ENSG00000141664homo_sapiensENSP0000026949975.636773.6842ictidomys_tridecemlineatusENSSTOP0000001376197.270794.7598
ENSG00000141664homo_sapiensENSP0000026949971.392269.7793otolemur_garnettiiENSOGAP0000002125998.247796.028
ENSG00000141664homo_sapiensENSP0000026949998.217397.6231cebus_imitatorENSCCAP0000000849498.13497.5403
ENSG00000141664homo_sapiensENSP0000026949996.434694.2275urocitellus_parryiiENSUPAP0001003040196.352894.1476
ENSG00000141664homo_sapiensENSP0000026949981.154574.3633moschus_moschiferusENSMMSP0000000274485.586478.4244
ENSG00000141664homo_sapiensENSP0000026949992.27591.7657rhinopithecus_roxellanaENSRROP0000002060899.088498.5415
ENSG00000141664homo_sapiensENSP0000026949990.407586.4177mus_pahariMGP_PahariEiJ_P007465690.638386.6383
ENSG00000141664homo_sapiensENSP0000026949992.190290.2377propithecus_coquereliENSPCOP0000002137495.682893.6564
ENSG00000141664homo_sapiensENSP0000026949922.665513.3277drosophila_melanogasterFBpp008069232.96319.3827
ENSG00000141664homo_sapiensENSP0000026949933.786124.618callorhinchus_miliiENSCMIP0000003695665.032747.3856
ENSG00000141664homo_sapiensENSP0000026949919.864215.8744latimeria_chalumnaeENSLACP0000000136167.826154.2029
ENSG00000141664homo_sapiensENSP0000026949960.101947.9627xenopus_tropicalisENSXETP0000005837268.142454.3792
ENSG00000141664homo_sapiensENSP0000026949979.20270.798chrysemys_picta_belliiENSCPBP0000003847980.919372.333
ENSG00000141664homo_sapiensENSP0000026949972.835365.8744sphenodon_punctatusENSSPUP0000000902479.665772.052
ENSG00000141664homo_sapiensENSP0000026949975.212266.893crocodylus_porosusENSCPRP0000502511882.265573.1662
ENSG00000141664homo_sapiensENSP0000026949971.731859.9321laticauda_laticaudataENSLLTP0000000511371.428659.6788
ENSG00000141664homo_sapiensENSP0000026949969.100258.4041notechis_scutatusENSNSUP0000002621574.337962.8311
ENSG00000141664homo_sapiensENSP0000026949973.259862.0543pseudonaja_textilisENSPTXP0000002656172.460161.377
ENSG00000141664homo_sapiensENSP0000026949979.96671.562anas_platyrhynchos_platyrhynchosENSAPLP0000000308278.044769.8426
ENSG00000141664homo_sapiensENSP0000026949974.957667.3175gallus_gallusENSGALP0001001645083.301974.8113
ENSG00000141664homo_sapiensENSP0000026949975.042467.2326meleagris_gallopavoENSMGAP0000000469580.583472.1969
ENSG00000141664homo_sapiensENSP0000026949964.855757.6401serinus_canariaENSSCAP0000000445276.938668.3786
ENSG00000141664homo_sapiensENSP0000026949975.297167.5722parus_majorENSPMJP0000000197783.521774.9529
ENSG00000141664homo_sapiensENSP0000026949973.174962.4788anolis_carolinensisENSACAP0000001159376.081264.9603
ENSG00000141664homo_sapiensENSP0000026949973.0961.4601naja_najaENSNNAP0000002371772.535860.9941
ENSG00000141664homo_sapiensENSP0000026949973.005162.3939podarcis_muralisENSPMRP0000000900663.421854.2035
ENSG00000141664homo_sapiensENSP0000026949963.157956.1969geospiza_fortisENSGFOP0000002123983.035773.8839
ENSG00000141664homo_sapiensENSP0000026949979.626571.2224taeniopygia_guttataENSTGUP0000002119579.156170.8017
ENSG00000141664homo_sapiensENSP0000026949973.599362.9881salvator_merianaeENSSMRP0000001122073.599362.9881
ENSG00000141664homo_sapiensENSP0000026949948.811542.3599pelodiscus_sinensisENSPSIP0000000859484.310973.1672
ENSG00000141664homo_sapiensENSP0000026949974.872766.893gopherus_evgoodeiENSGEVP0000500550385.05375.9884
ENSG00000141664homo_sapiensENSP0000026949955.008547.6231struthio_camelus_australisENSSCUP0000001671083.183672.0154
ENSG00000141664homo_sapiensENSP0000026949980.135871.9015anser_brachyrhynchusENSABRP0000001365679.06270.938
ENSG00000141664homo_sapiensENSP0000026949976.061168.5908strigops_habroptilaENSSHBP0000500445281.012773.0561
ENSG00000141664homo_sapiensENSP0000026949978.862570.5433terrapene_carolina_triunguisENSTMTP0000000920981.562872.9587
ENSG00000141664homo_sapiensENSP0000026949975.891367.8268aquila_chrysaetos_chrysaetosENSACCP0002002309984.499175.5199
ENSG00000141664homo_sapiensENSP0000026949974.448266.6384ficedula_albicollisENSFALP0000001354881.657473.0912
ENSG00000141664homo_sapiensENSP0000026949976.230968.2513coturnix_japonicaENSCJPP0000502086278.154969.9739
ENSG00000141664homo_sapiensENSP0000026949961.460150leptobrachium_leishanenseENSLLEP0000001996866.913154.4362

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003676enables nucleic acid binding1IEAHomo_sapiens(9606)Function
GO:0005737located_in cytoplasm1IDAHomo_sapiens(9606)Component
GO:0008270enables zinc ion binding1IEAHomo_sapiens(9606)Function
GO:0035091enables phosphatidylinositol binding1IEAHomo_sapiens(9606)Function

Expression