Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases N.A.
Drug Drug
Main interacting RNAs N.A.
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq

Description

Ensembl ID ENSG00000141564 Gene ID 57521 Accession 30287
Symbol RPTOR Alias Full Name
Status Confidence Length 421550 bases Strand Plus strand
Position 17 : 80544819 - 80966368 RNA binding domain N.A.
Summary

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
RPTOR-208 ENST00000574767 2461 95aa ENSP00000459701
RPTOR-211 ENST00000577161 3633 No protein -
RPTOR-201 ENST00000306801 6838 1335aa ENSP00000307272
RPTOR-213 ENST00000697423 6838 1353aa ENSP00000513305
RPTOR-212 ENST00000649732 2499 No protein -
RPTOR-203 ENST00000570891 2286 379aa ENSP00000460136
RPTOR-202 ENST00000544334 5734 1177aa ENSP00000442479
RPTOR-206 ENST00000573746 688 No protein -
RPTOR-204 ENST00000572733 424 No protein -
RPTOR-209 ENST00000575542 5536 No protein -
RPTOR-210 ENST00000576366 787 235aa ENSP00000460940
RPTOR-207 ENST00000573837 443 No protein -
RPTOR-205 ENST00000573163 501 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
26422Blood Pressure3.0510000E-005-
26456Blood Pressure9.4100000E-005-
26879Blood Pressure1.2750000E-005-
26897Blood Pressure7.9020000E-005-
26905Blood Pressure8.9430000E-005-
27014Blood Pressure6.9960000E-005-
35099Platelet Function Tests2.2304700E-005-
39649Platelet Function Tests1.3048300E-005-
39910Platelet Function Tests2.8965900E-005-
44953Platelet Function Tests3.1423611E-006-
44955Platelet Function Tests4.1482005E-006-
44956Platelet Function Tests2.6898337E-006-
44961Platelet Function Tests1.6369963E-006-
44968Platelet Function Tests7.5636642E-007-
69430Schizophrenia7E-626198764
85257Bronchial Provocation Tests9E-625514360
85258Pulmonary Disease, Chronic Obstructive9E-625514360
87397Body Mass Index5E-725673413
89550Body Mass Index2E-925673413
89551Myopia, Degenerative2E-623049088
93643Body Mass Index4E-1025673413
100815Obesity2E-823563607

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0001002enables RNA polymerase III type 1 promoter sequence-specific DNA binding1IDAHomo_sapiens(9606)Function
GO:0001003enables RNA polymerase III type 2 promoter sequence-specific DNA binding1IDAHomo_sapiens(9606)Function
GO:0001006enables RNA polymerase III type 3 promoter sequence-specific DNA binding1IDAHomo_sapiens(9606)Function
GO:0001156enables TFIIIC-class transcription factor complex binding1IDAHomo_sapiens(9606)Function
GO:0001558involved_in regulation of cell growth1IMPHomo_sapiens(9606)Process
GO:0001938involved_in positive regulation of endothelial cell proliferation1IEAHomo_sapiens(9606)Process
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm2IBA,IDAHomo_sapiens(9606)Component
GO:0005764located_in lysosome2IDA,IMPHomo_sapiens(9606)Component
GO:0005765located_in lysosomal membrane1HDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol2IDA,TASHomo_sapiens(9606)Component
GO:0006974involved_in DNA damage response1NASHomo_sapiens(9606)Process
GO:0008361involved_in regulation of cell size1IMPHomo_sapiens(9606)Process
GO:0009267involved_in cellular response to starvation1IBAHomo_sapiens(9606)Process
GO:0009410involved_in response to xenobiotic stimulus1ISSHomo_sapiens(9606)Process
GO:0010494located_in cytoplasmic stress granule1IDAHomo_sapiens(9606)Component
GO:0010506involved_in regulation of autophagy1IBAHomo_sapiens(9606)Process
GO:0010507involved_in negative regulation of autophagy1NASHomo_sapiens(9606)Process
GO:0010800involved_in positive regulation of peptidyl-threonine phosphorylation1IMPHomo_sapiens(9606)Process
GO:0016310involved_in phosphorylation1IDAHomo_sapiens(9606)Process
GO:0019901enables protein kinase binding1IPIHomo_sapiens(9606)Function
GO:0030291enables protein serine/threonine kinase inhibitor activity1IDAHomo_sapiens(9606)Function
GO:0030295enables protein kinase activator activity1IDAHomo_sapiens(9606)Function
GO:0030307involved_in positive regulation of cell growth3IBA,IMP,NASHomo_sapiens(9606)Process
GO:0030425located_in dendrite1IEAHomo_sapiens(9606)Component
GO:0030674enables protein-macromolecule adaptor activity2IBA,IDAHomo_sapiens(9606)Function
GO:0031669involved_in cellular response to nutrient levels2IMP,NASHomo_sapiens(9606)Process
GO:0031929involved_in TOR signaling1IDAHomo_sapiens(9606)Process
GO:0031931part_of TORC1 complex3IBA,IDA,IPIHomo_sapiens(9606)Component
GO:0032008involved_in positive regulation of TOR signaling1IDAHomo_sapiens(9606)Process
GO:0033138involved_in positive regulation of peptidyl-serine phosphorylation1IMPHomo_sapiens(9606)Process
GO:0035176involved_in social behavior1ISSHomo_sapiens(9606)Process
GO:0038202involved_in TORC1 signaling2IBA,IMPHomo_sapiens(9606)Process
GO:0043025located_in neuronal cell body1IEAHomo_sapiens(9606)Component
GO:0044877enables protein-containing complex binding1IPIHomo_sapiens(9606)Function
GO:0045821involved_in positive regulation of glycolytic process1NASHomo_sapiens(9606)Process
GO:0045945involved_in positive regulation of transcription by RNA polymerase III1IMPHomo_sapiens(9606)Process
GO:0046889involved_in positive regulation of lipid biosynthetic process1NASHomo_sapiens(9606)Process
GO:0071230involved_in cellular response to amino acid stimulus2IBA,IMPHomo_sapiens(9606)Process
GO:0071233involved_in cellular response to leucine1IDAHomo_sapiens(9606)Process
GO:0071456involved_in cellular response to hypoxia1NASHomo_sapiens(9606)Process
GO:0071470involved_in cellular response to osmotic stress1NASHomo_sapiens(9606)Process
GO:0071889enables 14-3-3 protein binding1IDAHomo_sapiens(9606)Function
GO:0071902involved_in positive regulation of protein serine/threonine kinase activity2IBA,IDAHomo_sapiens(9606)Process
GO:1900087involved_in positive regulation of G1/S transition of mitotic cell cycle1IMPHomo_sapiens(9606)Process
GO:1905857involved_in positive regulation of pentose-phosphate shunt1NASHomo_sapiens(9606)Process

Expression