RBP Type
Non-canonical_RBPs
Diseases
N.A.
Drug
N.A.
Main interacting RNAs
N.A.
Moonlighting functions
Metabolic enzyme
Localizations
N.A.
BulkPerturb-seq
Ensembl ID ENSG00000141526 Gene ID
9123
Accession
10924
Symbol
SLC16A3
Alias
MCT3;MCT4;MCT3;MCT4;MCT-3;MCT-4
Full Name
solute carrier family 16 member 3
Status
Confidence
Length
43196 bases
Strand
Plus strand
Position
17 : 82217934 - 82261129
RNA binding domain
N.A.
Summary
Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).[supplied by OMIM, Mar 2008]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
Name
Transcript ID
bp
Protein
Translation ID
SLC16A3-208
ENST00000580098
2676
410aa
ENSP00000463880
SLC16A3-216
ENST00000584689
2667
465aa
ENSP00000464625
SLC16A3-202
ENST00000392341
2659
465aa
ENSP00000376152
SLC16A3-211
ENST00000581642
557
No protein
-
SLC16A3-213
ENST00000582743
2599
465aa
ENSP00000462405
SLC16A3-215
ENST00000583444
2882
No protein
-
SLC16A3-217
ENST00000584781
562
No protein
-
SLC16A3-205
ENST00000578684
2439
417aa
ENSP00000463912
SLC16A3-203
ENST00000577650
2503
439aa
ENSP00000463063
SLC16A3-204
ENST00000578574
958
No protein
-
SLC16A3-207
ENST00000579572
863
No protein
-
SLC16A3-212
ENST00000582715
279
79aa
ENSP00000464326
SLC16A3-201
ENST00000392339
2662
465aa
ENSP00000376150
SLC16A3-210
ENST00000581287
4830
465aa
ENSP00000463978
SLC16A3-218
ENST00000617373
2636
465aa
ENSP00000483212
SLC16A3-209
ENST00000580189
2711
465aa
ENSP00000464112
SLC16A3-219
ENST00000619321
2603
465aa
ENSP00000482013
SLC16A3-206
ENST00000578810
678
No protein
-
SLC16A3-214
ENST00000583025
955
306aa
ENSP00000463005
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0003723 enables RNA binding 1 HDA Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005886 located_in plasma membrane 2 IDA,TAS Homo_sapiens(9606) Component GO:0008028 enables monocarboxylic acid transmembrane transporter activity 1 IBA Homo_sapiens(9606) Function GO:0015650 enables lactate:proton symporter activity 1 IDA Homo_sapiens(9606) Function GO:0015718 involved_in monocarboxylic acid transport 1 IBA Homo_sapiens(9606) Process GO:0016020 located_in membrane 1 TAS Homo_sapiens(9606) Component GO:0016323 located_in basolateral plasma membrane 1 IDA Homo_sapiens(9606) Component GO:0016324 located_in apical plasma membrane 1 IDA Homo_sapiens(9606) Component GO:0016328 located_in lateral plasma membrane 1 IDA Homo_sapiens(9606) Component GO:0030163 involved_in protein catabolic process 1 IDA Homo_sapiens(9606) Process GO:0031965 located_in nuclear membrane 1 IDA Homo_sapiens(9606) Component GO:0035873 involved_in lactate transmembrane transport 1 IDA Homo_sapiens(9606) Process GO:0042867 involved_in pyruvate catabolic process 1 IEA Homo_sapiens(9606) Process GO:0045202 is_active_in synapse 1 IDA Homo_sapiens(9606) Component GO:0050833 enables pyruvate transmembrane transporter activity 1 IDA Homo_sapiens(9606) Function GO:1901475 involved_in pyruvate transmembrane transport 1 IDA Homo_sapiens(9606) Process
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