RBP Type
Non-canonical_RBPs
Diseases
Drug
N.A.
Main interacting RNAs
mRNA
Moonlighting functions
N.A.
Localizations
N.A.
BulkPerturb-seq
N.A.
Ensembl ID ENSG00000140939 Gene ID
8996 Accession
7869
Symbol
NOL3
Alias
ARC;FCM;MYP;NOP;NOP30;MYOCL1
Full Name
nucleolar protein 3
Status
Confidence
Length
5584 bases
Strand
Plus strand
Position
16 : 67170154 - 67175737
RNA binding domain
N.A.
Summary
This gene encodes an anti-apoptotic protein that has been shown to down-regulate the enzyme activities of caspase 2, caspase 8 and tumor protein p53. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
32510328 FMRP promotes RNA localization to neuronal projections through interactions between its RGG domain and G-quadruplex RNA sequences.
Raeann Goering
2020-06-08
eLife
Name
Transcript ID
bp
Protein
Translation ID
NOL3-206
ENST00000565560
579
174aa
ENSP00000457732
NOL3-202
ENST00000563439
642
138aa
ENSP00000454256
NOL3-209
ENST00000568086
578
No protein
-
NOL3-205
ENST00000564992
1355
208aa
ENSP00000457720
NOL3-203
ENST00000564053
1592
208aa
ENSP00000457243
NOL3-207
ENST00000565645
519
No protein
-
NOL3-211
ENST00000568199
613
No protein
-
NOL3-208
ENST00000566871
752
216aa
ENSP00000455808
NOL3-212
ENST00000568503
1511
No protein
-
NOL3-201
ENST00000563258
794
131aa
ENSP00000463698
NOL3-210
ENST00000568146
1351
219aa
ENSP00000454598
NOL3-204
ENST00000564860
317
106aa
ENSP00000463685
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
17219 Cholesterol, HDL 1.717e-007 19060910
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000140939 homo_sapiens ENSP00000254691 8.77531 5.49662 homo_sapiens ENSP00000454598 41.5525 26.0274
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000140939 homo_sapiens ENSP00000454598 97.7169 97.2603 pan_paniscus ENSPPAP00000035457 97.7169 97.2603 ENSG00000140939 homo_sapiens ENSP00000454598 53.4247 50.6849 pongo_abelii ENSPPYP00000008408 43.4944 41.2639 ENSG00000140939 homo_sapiens ENSP00000454598 97.7169 97.2603 pan_troglodytes ENSPTRP00000073533 97.7169 97.2603 ENSG00000140939 homo_sapiens ENSP00000454598 53.4247 50.6849 gorilla_gorilla ENSGGOP00000011979 40.7666 38.676 ENSG00000140939 homo_sapiens ENSP00000454598 42.9224 35.1598 ornithorhynchus_anatinus ENSOANP00000039328 39.4958 32.3529 ENSG00000140939 homo_sapiens ENSP00000454598 41.0959 29.2237 sarcophilus_harrisii ENSSHAP00000012853 39.823 28.3186 ENSG00000140939 homo_sapiens ENSP00000454598 64.3836 58.9041 echinops_telfairi ENSETEP00000005576 63.2287 57.8475 ENSG00000140939 homo_sapiens ENSP00000454598 53.4247 49.7717 callithrix_jacchus ENSCJAP00000030323 53.1818 49.5455 ENSG00000140939 homo_sapiens ENSP00000454598 54.7945 52.0548 cercocebus_atys ENSCATP00000022387 46.1538 43.8462 ENSG00000140939 homo_sapiens ENSP00000454598 53.8813 51.1416 macaca_fascicularis ENSMFAP00000024570 57.2816 54.3689 ENSG00000140939 homo_sapiens ENSP00000454598 53.8813 51.1416 macaca_mulatta ENSMMUP00000070767 57.2816 54.3689 ENSG00000140939 homo_sapiens ENSP00000454598 54.7945 52.0548 macaca_nemestrina ENSMNEP00000012812 46.1538 43.8462 ENSG00000140939 homo_sapiens ENSP00000454598 92.6941 89.9543 papio_anubis ENSPANP00000040881 93.5484 90.7834 ENSG00000140939 homo_sapiens ENSP00000454598 38.8128 35.1598 mandrillus_leucophaeus ENSMLEP00000035152 69.6721 63.1148 ENSG00000140939 homo_sapiens ENSP00000454598 44.2922 43.379 tursiops_truncatus ENSTTRP00000009720 47.0874 46.1165 ENSG00000140939 homo_sapiens ENSP00000454598 52.0548 48.8584 vulpes_vulpes ENSVVUP00000015743 51.3514 48.1982 ENSG00000140939 homo_sapiens ENSP00000454598 51.1416 46.5753 mus_spretus MGP_SPRETEiJ_P0089282 50.4505 45.9459 ENSG00000140939 homo_sapiens ENSP00000454598 50.6849 47.032 equus_asinus ENSEASP00005056982 43.7008 40.5512 ENSG00000140939 homo_sapiens ENSP00000454598 50.2283 45.6621 capra_hircus ENSCHIP00000017303 47.8261 43.4783 ENSG00000140939 homo_sapiens ENSP00000454598 48.8584 45.6621 loxodonta_africana ENSLAFP00000025567 56.9149 53.1915 ENSG00000140939 homo_sapiens ENSP00000454598 50.6849 47.4886 panthera_leo ENSPLOP00000019717 54.1463 50.7317 ENSG00000140939 homo_sapiens ENSP00000454598 49.3151 46.5753 ailuropoda_melanoleuca ENSAMEP00000018233 52.9412 50 ENSG00000140939 homo_sapiens ENSP00000454598 49.3151 45.2055 bos_indicus_hybrid ENSBIXP00005017604 52.4272 48.0583 ENSG00000140939 homo_sapiens ENSP00000454598 52.968 48.4018 oryctolagus_cuniculus ENSOCUP00000008624 54.717 50 ENSG00000140939 homo_sapiens ENSP00000454598 52.5114 48.8584 canis_lupus_familiaris ENSCAFP00845013639 56.3725 52.451 ENSG00000140939 homo_sapiens ENSP00000454598 50.2283 47.032 panthera_pardus ENSPPRP00000028257 54.1872 50.7389 ENSG00000140939 homo_sapiens ENSP00000454598 52.5114 46.5753 marmota_marmota_marmota ENSMMMP00000000265 58.0808 51.5152 ENSG00000140939 homo_sapiens ENSP00000454598 69.863 65.2968 balaenoptera_musculus ENSBMSP00010023371 64.557 60.3376 ENSG00000140939 homo_sapiens ENSP00000454598 50.2283 44.2922 cavia_porcellus ENSCPOP00000004452 53.1401 46.8599 ENSG00000140939 homo_sapiens ENSP00000454598 51.5982 47.4886 felis_catus ENSFCAP00000060422 51.8349 47.7064 ENSG00000140939 homo_sapiens ENSP00000454598 50.2283 47.9452 ursus_americanus ENSUAMP00000020116 49.5495 47.2973 ENSG00000140939 homo_sapiens ENSP00000454598 40.1826 31.0502 monodelphis_domestica ENSMODP00000007693 31.5412 24.3728 ENSG00000140939 homo_sapiens ENSP00000454598 68.0365 63.4703 bison_bison_bison ENSBBBP00000006366 66.5179 62.0536 ENSG00000140939 homo_sapiens ENSP00000454598 50.6849 46.5753 monodon_monoceros ENSMMNP00015003935 42.5287 39.0805 ENSG00000140939 homo_sapiens ENSP00000454598 52.5114 49.3151 microcebus_murinus ENSMICP00000041571 54.7619 51.4286 ENSG00000140939 homo_sapiens ENSP00000454598 50.6849 45.6621 octodon_degus ENSODEP00000021661 52.8571 47.619 ENSG00000140939 homo_sapiens ENSP00000454598 52.5114 47.032 jaculus_jaculus ENSJJAP00000025008 51.5695 46.1883 ENSG00000140939 homo_sapiens ENSP00000454598 50.2283 46.1187 ovis_aries_rambouillet ENSOARP00020024095 49.1071 45.0893 ENSG00000140939 homo_sapiens ENSP00000454598 47.032 41.5525 ochotona_princeps ENSOPRP00000013795 53.9267 47.644 ENSG00000140939 homo_sapiens ENSP00000454598 50.6849 46.5753 delphinapterus_leucas ENSDLEP00000003232 54.9505 50.495 ENSG00000140939 homo_sapiens ENSP00000454598 51.1416 46.5753 physeter_catodon ENSPCTP00005021643 40.4332 36.8231 ENSG00000140939 homo_sapiens ENSP00000454598 52.5114 47.032 mus_caroli MGP_CAROLIEiJ_P0085783 55.2885 49.5192 ENSG00000140939 homo_sapiens ENSP00000454598 50.6849 46.1187 mus_musculus ENSMUSP00000014920 50.4545 45.9091 ENSG00000140939 homo_sapiens ENSP00000454598 52.968 47.9452 dipodomys_ordii ENSDORP00000027347 51.3274 46.4602 ENSG00000140939 homo_sapiens ENSP00000454598 49.3151 46.1187 mustela_putorius_furo ENSMPUP00000005488 49.7696 46.5438 ENSG00000140939 homo_sapiens ENSP00000454598 53.4247 49.7717 aotus_nancymaae ENSANAP00000020674 43.985 40.9774 ENSG00000140939 homo_sapiens ENSP00000454598 52.0548 48.8584 saimiri_boliviensis_boliviensis ENSSBOP00000036164 47.1074 44.2149 ENSG00000140939 homo_sapiens ENSP00000454598 54.3379 51.5982 chlorocebus_sabaeus ENSCSAP00000000148 44.9057 42.6415 ENSG00000140939 homo_sapiens ENSP00000454598 64.8402 60.274 tupaia_belangeri ENSTBEP00000005629 69.2683 64.3902 ENSG00000140939 homo_sapiens ENSP00000454598 50.6849 45.2055 mesocricetus_auratus ENSMAUP00000002305 53.8835 48.0583 ENSG00000140939 homo_sapiens ENSP00000454598 50.6849 46.1187 phocoena_sinus ENSPSNP00000024612 54.9505 50 ENSG00000140939 homo_sapiens ENSP00000454598 48.8584 44.2922 camelus_dromedarius ENSCDRP00005013607 49.7674 45.1163 ENSG00000140939 homo_sapiens ENSP00000454598 48.8584 44.2922 carlito_syrichta ENSTSYP00000017505 50.7109 45.9716 ENSG00000140939 homo_sapiens ENSP00000454598 41.0959 36.9863 panthera_tigris_altaica ENSPTIP00000006544 47.3684 42.6316 ENSG00000140939 homo_sapiens ENSP00000454598 52.5114 47.9452 rattus_norvegicus ENSRNOP00000020908 52.0362 47.5113 ENSG00000140939 homo_sapiens ENSP00000454598 50.6849 47.4886 prolemur_simus ENSPSMP00000013099 44.2231 41.4343 ENSG00000140939 homo_sapiens ENSP00000454598 49.7717 45.2055 microtus_ochrogaster ENSMOCP00000013674 52.4038 47.5962 ENSG00000140939 homo_sapiens ENSP00000454598 60.7306 54.3379 sorex_araneus ENSSARP00000007478 67.8571 60.7143 ENSG00000140939 homo_sapiens ENSP00000454598 51.5982 46.5753 peromyscus_maniculatus_bairdii ENSPEMP00000002936 55.122 49.7561 ENSG00000140939 homo_sapiens ENSP00000454598 50.2283 46.1187 bos_mutus ENSBMUP00000005630 53.3981 49.0291 ENSG00000140939 homo_sapiens ENSP00000454598 50.6849 46.1187 mus_spicilegus ENSMSIP00000016337 50.9174 46.3303 ENSG00000140939 homo_sapiens ENSP00000454598 50.6849 45.2055 cricetulus_griseus_chok1gshd ENSCGRP00001016339 49.3333 44 ENSG00000140939 homo_sapiens ENSP00000454598 47.032 44.7489 pteropus_vampyrus ENSPVAP00000000375 50.2439 47.8049 ENSG00000140939 homo_sapiens ENSP00000454598 51.5982 46.5753 myotis_lucifugus ENSMLUP00000010139 42.0074 37.9182 ENSG00000140939 homo_sapiens ENSP00000454598 44.7489 31.9635 vombatus_ursinus ENSVURP00010028303 43.9462 31.3901 ENSG00000140939 homo_sapiens ENSP00000454598 79.4521 75.3425 rhinolophus_ferrumequinum ENSRFEP00010020210 79.4521 75.3425 ENSG00000140939 homo_sapiens ENSP00000454598 49.3151 46.1187 neovison_vison ENSNVIP00000013388 46.7532 43.7229 ENSG00000140939 homo_sapiens ENSP00000454598 50.2283 46.1187 bos_taurus ENSBTAP00000004574 53.3981 49.0291 ENSG00000140939 homo_sapiens ENSP00000454598 51.5982 45.6621 heterocephalus_glaber_female ENSHGLP00000032541 46.5021 41.1523 ENSG00000140939 homo_sapiens ENSP00000454598 53.4247 50.6849 rhinopithecus_bieti ENSRBIP00000029063 58.209 55.2239 ENSG00000140939 homo_sapiens ENSP00000454598 54.7945 52.0548 rhinopithecus_bieti ENSRBIP00000020147 44.2804 42.0664 ENSG00000140939 homo_sapiens ENSP00000454598 51.1416 48.4018 canis_lupus_dingo ENSCAFP00020022876 48.9083 46.2882 ENSG00000140939 homo_sapiens ENSP00000454598 51.1416 47.032 sciurus_vulgaris ENSSVLP00005030981 41.791 38.4328 ENSG00000140939 homo_sapiens ENSP00000454598 44.7489 33.3333 phascolarctos_cinereus ENSPCIP00000023110 43.9462 32.7354 ENSG00000140939 homo_sapiens ENSP00000454598 50.6849 46.5753 procavia_capensis ENSPCAP00000012177 53.3654 49.0385 ENSG00000140939 homo_sapiens ENSP00000454598 51.5982 45.6621 nannospalax_galili ENSNGAP00000006738 52.5581 46.5116 ENSG00000140939 homo_sapiens ENSP00000454598 66.21 63.0137 bos_grunniens ENSBGRP00000042999 59.9174 57.0248 ENSG00000140939 homo_sapiens ENSP00000454598 50.6849 46.5753 chinchilla_lanigera ENSCLAP00000015782 52.6066 48.3412 ENSG00000140939 homo_sapiens ENSP00000454598 69.4064 66.21 cervus_hanglu_yarkandensis ENSCHYP00000035621 69.7248 66.5138 ENSG00000140939 homo_sapiens ENSP00000454598 68.0365 62.5571 catagonus_wagneri ENSCWAP00000027040 67.1171 61.7117 ENSG00000140939 homo_sapiens ENSP00000454598 54.3379 47.4886 ictidomys_tridecemlineatus ENSSTOP00000020367 56.6667 49.5238 ENSG00000140939 homo_sapiens ENSP00000454598 50.2283 48.4018 otolemur_garnettii ENSOGAP00000017318 50.4587 48.6239 ENSG00000140939 homo_sapiens ENSP00000454598 52.968 49.3151 cebus_imitator ENSCCAP00000013855 44.9612 41.8605 ENSG00000140939 homo_sapiens ENSP00000454598 53.8813 47.032 urocitellus_parryii ENSUPAP00010002247 57.561 50.2439 ENSG00000140939 homo_sapiens ENSP00000454598 68.9498 65.2968 moschus_moschiferus ENSMMSP00000002904 60.8871 57.6613 ENSG00000140939 homo_sapiens ENSP00000454598 54.7945 52.0548 rhinopithecus_roxellana ENSRROP00000019900 46.1538 43.8462 ENSG00000140939 homo_sapiens ENSP00000454598 51.1416 46.5753 mus_pahari MGP_PahariEiJ_P0054037 54.3689 49.5146 ENSG00000140939 homo_sapiens ENSP00000454598 52.5114 48.8584 propithecus_coquereli ENSPCOP00000002276 56.3725 52.451
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0003723 enables RNA binding 1 TAS Homo_sapiens(9606) Function GO:0005123 enables death receptor binding 1 IBA Homo_sapiens(9606) Function GO:0005509 enables calcium ion binding 1 IMP Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005730 located_in nucleolus 1 IEA Homo_sapiens(9606) Component GO:0005739 is_active_in mitochondrion 2 IBA,ISS Homo_sapiens(9606) Component GO:0005829 located_in cytosol 1 TAS Homo_sapiens(9606) Component GO:0006376 involved_in mRNA splice site recognition 1 IDA Homo_sapiens(9606) Process GO:0006915 involved_in apoptotic process 1 IEA Homo_sapiens(9606) Process GO:0008380 involved_in RNA splicing 1 TAS Homo_sapiens(9606) Process GO:0014808 involved_in release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 1 IDA Homo_sapiens(9606) Process GO:0016020 located_in membrane 1 IEA Homo_sapiens(9606) Component GO:0016529 located_in sarcoplasmic reticulum 1 IEA Homo_sapiens(9606) Component GO:0035877 enables death effector domain binding 1 IBA Homo_sapiens(9606) Function GO:0042802 enables identical protein binding 1 IPI Homo_sapiens(9606) Function GO:0043027 enables cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2 IBA,IDA Homo_sapiens(9606) Function GO:0043066 involved_in negative regulation of apoptotic process 1 IMP Homo_sapiens(9606) Process GO:0051259 involved_in protein complex oligomerization 1 IDA Homo_sapiens(9606) Process GO:0089720 enables caspase binding 2 IBA,IPI Homo_sapiens(9606) Function GO:0090201 involved_in negative regulation of release of cytochrome c from mitochondria 2 IBA,IDA Homo_sapiens(9606) Process GO:1902176 involved_in negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 1 IDA Homo_sapiens(9606) Process GO:1903298 involved_in negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway 1 ISS Homo_sapiens(9606) Process GO:1990001 involved_in inhibition of cysteine-type endopeptidase activity involved in apoptotic process 2 IBA,IDA Homo_sapiens(9606) Process GO:2001237 involved_in negative regulation of extrinsic apoptotic signaling pathway 2 IBA,IDA Homo_sapiens(9606) Process GO:2001243 involved_in negative regulation of intrinsic apoptotic signaling pathway 1 IBA Homo_sapiens(9606) Process
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