Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases N.A.
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions Metabolic enzyme
Localizations N.A.
BulkPerturb-seq

Description

Ensembl ID ENSG00000140876 Gene ID 283927 Accession 8054
Symbol NUDT7 Alias NA Full Name nudix hydrolase 7
Status Confidence Length 19769 bases Strand Plus strand
Position 16 : 77722492 - 77742260 RNA binding domain N.A.
Summary The protein encoded by this gene is a member of the Nudix hydrolase family. Nudix hydrolases eliminate potentially toxic nucleotide metabolites from the cell and regulate the concentrations and availability of many different nucleotide substrates, cofactors, and signaling molecules. Alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
NUDT7-205 ENST00000564085 899 170aa ENSP00000457566
NUDT7-201 ENST00000268533 1096 238aa ENSP00000268533
NUDT7-206 ENST00000568787 678 120aa ENSP00000456363
NUDT7-202 ENST00000437314 930 185aa ENSP00000387707
NUDT7-203 ENST00000563839 316 15aa ENSP00000454617
NUDT7-204 ENST00000564031 725 No protein -
NUDT7-207 ENST00000613075 1073 223aa ENSP00000479582

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
32917Glomerular Filtration Rate8.8327153E-005-
44088Platelet Function Tests6.9557891E-007-
54140oxidized low density lipoprotein3.6020000E-005-
97651Folic Acid7E-623251661

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000287enables magnesium ion binding1ISSHomo_sapiens(9606)Function
GO:0003674enables molecular_function1NDHomo_sapiens(9606)Function
GO:0005777located_in peroxisome1ISSHomo_sapiens(9606)Component
GO:0005782located_in peroxisomal matrix1TASHomo_sapiens(9606)Component
GO:0005829located_in cytosol1TASHomo_sapiens(9606)Component
GO:0008150involved_in biological_process1NDHomo_sapiens(9606)Process
GO:0009132involved_in nucleoside diphosphate metabolic process1IEAHomo_sapiens(9606)Process
GO:0010945enables CoA pyrophosphatase activity1ISSHomo_sapiens(9606)Function
GO:0015938involved_in coenzyme A catabolic process2IBA,ISSHomo_sapiens(9606)Process
GO:0030145enables manganese ion binding1IEAHomo_sapiens(9606)Function
GO:0030515enables snoRNA binding1ISSHomo_sapiens(9606)Function
GO:0036114involved_in medium-chain fatty-acyl-CoA catabolic process1ISSHomo_sapiens(9606)Process
GO:0044580involved_in butyryl-CoA catabolic process1ISSHomo_sapiens(9606)Process
GO:0046356involved_in acetyl-CoA catabolic process1ISSHomo_sapiens(9606)Process
GO:0050873involved_in brown fat cell differentiation1IEAHomo_sapiens(9606)Process
GO:0140933NOT enables 5-(N(7)-methylguanosine 5-triphospho)-[mRNA] hydrolase activity1ISSHomo_sapiens(9606)Function
GO:1901289involved_in succinyl-CoA catabolic process1ISSHomo_sapiens(9606)Process
GO:1902858involved_in propionyl-CoA metabolic process1ISSHomo_sapiens(9606)Process
GO:1902859involved_in propionyl-CoA catabolic process1ISSHomo_sapiens(9606)Process
GO:2001294involved_in malonyl-CoA catabolic process1ISSHomo_sapiens(9606)Process

Expression