Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases N.A.
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions N.A.
Localizations Nucleoli
BulkPerturb-seq

Description

Ensembl ID ENSG00000140264 Gene ID 10169 Accession 10757
Symbol SERF2 Alias FAM2C;4F5REL;H4F5REL;HsT17089 Full Name small EDRK-rich factor 2
Status Confidence Length 27328 bases Strand Plus strand
Position 15 : 43777100 - 43804427 RNA binding domain N.A.
Summary Involved in protein destabilization. Predicted to be located in cytosol and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
30291272 Structural insights into pro-aggregation effects of C. elegans CRAM-1 and its human ortholog SERF2. Meenakshisundaram Balasubramaniam 2018-10-05 Scientific reports

Transcripts

Name Transcript ID bp Protein Translation ID
SERF2-214 ENST00000474290 548 No protein -
SERF2-203 ENST00000381359 1931 59aa ENSP00000370764
SERF2-217 ENST00000630046 862 108aa ENSP00000486542
SERF2-201 ENST00000249786 2543 59aa ENSP00000249786
SERF2-216 ENST00000486144 1030 No protein -
SERF2-210 ENST00000409960 1032 170aa ENSP00000387187
SERF2-209 ENST00000409646 559 83aa ENSP00000386316
SERF2-212 ENST00000445816 2099 59aa ENSP00000400178
SERF2-202 ENST00000339624 506 133aa ENSP00000339647
SERF2-206 ENST00000409291 807 42aa ENSP00000387041
SERF2-208 ENST00000409617 3254 40aa ENSP00000386290
SERF2-213 ENST00000448830 4630 108aa ENSP00000391027
SERF2-215 ENST00000475927 692 No protein -
SERF2-204 ENST00000402131 586 45aa ENSP00000386044
SERF2-205 ENST00000403425 690 45aa ENSP00000384300
SERF2-211 ENST00000430901 483 71aa ENSP00000394660
SERF2-207 ENST00000409614 582 45aa ENSP00000386783

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003674enables molecular_function1NDHomo_sapiens(9606)Function
GO:0005634located_in nucleus1ISSHomo_sapiens(9606)Component
GO:0005829located_in cytosol1ISSHomo_sapiens(9606)Component
GO:0031648involved_in protein destabilization1IMPHomo_sapiens(9606)Process

Expression