RBPWorld - a comprehensive database of RNA Binding Proteins

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RBP World!

Functions and Diseases

RBP Type	Non-canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Metabolic enzyme
Localizations	N.A.
BulkPerturb-seq

Description

Ensembl ID	ENSG00000139496	Gene ID	9818	Accession	20261
Symbol	NUP58	Alias	NUP45;NUPL1;PRO2463	Full Name	nucleoporin 58
Status	Confidence	Length	63867 bases	Strand	Plus strand
Position	13 : 25301524 - 25365390	RNA binding domain	N.A.
Summary	This gene encodes a member of the nucleoporin family that shares 87% sequence identity with rat nucleoporin p58. The protein is localized to the nuclear rim and is a component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
NUP58-206	ENST00000463407	6467	485aa	ENSP00000418555
NUP58-212	ENST00000481980	626	62aa	ENSP00000418341
NUP58-210	ENST00000477876	2234	570aa	ENSP00000512030
NUP58-211	ENST00000480187	588	No protein	-
NUP58-205	ENST00000460326	582	No protein	-
NUP58-207	ENST00000465068	551	No protein	-
NUP58-213	ENST00000490231	563	36aa	ENSP00000418244
NUP58-202	ENST00000381736	4236	599aa	ENSP00000371155
NUP58-208	ENST00000466694	1818	528aa	ENSP00000512032
NUP58-201	ENST00000381718	4180	587aa	ENSP00000371137
NUP58-216	ENST00000695572	3879	566aa	ENSP00000512029
NUP58-217	ENST00000695575	4167	584aa	ENSP00000512034
NUP58-214	ENST00000495460	1047	231aa	ENSP00000512035
NUP58-203	ENST00000381747	1659	510aa	ENSP00000371166
NUP58-204	ENST00000394327	1408	463aa	ENSP00000408147
NUP58-215	ENST00000695571	3742	131aa	ENSP00000512028
NUP58-218	ENST00000695577	1432	404aa	ENSP00000512036
NUP58-209	ENST00000476553	6018	No protein	-
NUP58-219	ENST00000695578	2026	36aa	ENSP00000512037

Gene Model

Click here to download ENSG00000139496's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000139496's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005635	located_in nuclear envelope	2	IDA,TAS	Homo_sapiens(9606)	Component
GO:0005643	part_of nuclear pore	2	IBA,NAS	Homo_sapiens(9606)	Component
GO:0006913	involved_in nucleocytoplasmic transport	1	NAS	Homo_sapiens(9606)	Process
GO:0008139	enables nuclear localization sequence binding	1	IBA	Homo_sapiens(9606)	Function
GO:0015031	involved_in protein transport	1	IEA	Homo_sapiens(9606)	Process
GO:0017056	enables structural constituent of nuclear pore	1	IBA	Homo_sapiens(9606)	Function
GO:0031965	located_in nuclear membrane	1	IEA	Homo_sapiens(9606)	Component
GO:0042306	involved_in regulation of protein import into nucleus	1	IEA	Homo_sapiens(9606)	Process
GO:0042802	enables identical protein binding	1	IEA	Homo_sapiens(9606)	Function
GO:0044877	enables protein-containing complex binding	1	IEA	Homo_sapiens(9606)	Function
GO:0051028	involved_in mRNA transport	1	IEA	Homo_sapiens(9606)	Process

Expression