Welcome to
RBP World!
Description
| Ensembl ID | ENSG00000138376 | Gene ID | 580 | Accession | 952 |
| Symbol | BARD1 | Alias | NA | Full Name | BRCA1 associated RING domain 1 |
| Status | Confidence | Length | 84038 bases | Strand | Minus strand |
| Position | 2 : 214725646 - 214809683 | RNA binding domain | N.A. | ||
| Summary | This gene encodes a protein which interacts with the N-terminal region of BRCA1. In addition to its ability to bind BRCA1 in vivo and in vitro, it shares homology with the 2 most conserved regions of BRCA1: the N-terminal RING motif and the C-terminal BRCT domain. The RING motif is a cysteine-rich sequence found in a variety of proteins that regulate cell growth, including the products of tumor suppressor genes and dominant protooncogenes. This protein also contains 3 tandem ankyrin repeats. The BARD1/BRCA1 interaction is disrupted by tumorigenic amino acid substitutions in BRCA1, implying that the formation of a stable complex between these proteins may be an essential aspect of BRCA1 tumor suppression. This protein may be the target of oncogenic mutations in breast or ovarian cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013] | ||||
RNA binding domains (RBDs)
| Protein | Domain | Pfam ID | E-value | Domain number |
|---|
RNA binding proteomes (RBPomes)
| Pubmed ID | Full Name | Cell | Author | Time | Doi |
|---|
Literatures on RNA binding capacity
| Pubmed ID | Title | Author | Time | Journal |
|---|---|---|---|---|
| 34591954 | The BRCA1/BARD1 ubiquitin ligase and its substrates. | R Samuel Witus | 2021-09-30 | The Biochemical journal |
| 25184681 | Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage. | J Sarah Hill | 2014-09-01 | Genes & development |
| 18842000 | The BARD1 C-terminal domain structure and interactions with polyadenylation factor CstF-50. | A Ross Edwards | 2008-11-04 | Biochemistry |
| 25806049 | Regulation of the DNA damage response by ubiquitin conjugation. | Kerstin Brinkmann | 2015-01-01 | Frontiers in genetics |
| 21087664 | BRCA1/BARD1 complex interacts with steroidogenic factor 1--A potential mechanism for regulation of aromatase expression by BRCA1. | Yunzhe Lu | 2011-01-01 | The Journal of steroid biochemistry and molecular biology |
Transcripts
| Name | Transcript ID | bp | Protein | Translation ID |
|---|---|---|---|---|
| BARD1-201 | ENST00000260947 | 5478 | 777aa | ENSP00000260947 |
| BARD1-206 | ENST00000471590 | 921 | No protein | - |
| BARD1-203 | ENST00000432456 | 615 | 44aa | ENSP00000405020 |
| BARD1-213 | ENST00000619009 | 946 | 264aa | ENSP00000482293 |
| BARD1-212 | ENST00000617164 | 2473 | 758aa | ENSP00000480470 |
| BARD1-210 | ENST00000613374 | 1111 | 307aa | ENSP00000484464 |
| BARD1-215 | ENST00000650978 | 3814 | 432aa | ENSP00000498880 |
| BARD1-211 | ENST00000613706 | 2131 | 641aa | ENSP00000484976 |
| BARD1-202 | ENST00000421162 | 1010 | 326aa | ENSP00000392245 |
| BARD1-209 | ENST00000613192 | 703 | 63aa | ENSP00000483275 |
| BARD1-204 | ENST00000455743 | 2261 | 76aa | ENSP00000412186 |
| BARD1-205 | ENST00000465841 | 175 | No protein | - |
| BARD1-207 | ENST00000471787 | 872 | No protein | - |
| BARD1-208 | ENST00000479904 | 573 | No protein | - |
| BARD1-214 | ENST00000620057 | 1456 | 127aa | ENSP00000481988 |
Phenotypes
| ensgID | Trait | pValue | Pubmed ID |
|---|---|---|---|
| 12042 | Neuroblastoma | 6.35E-6 | 18463370 |
| 16850 | Neuroblastoma | 1.11e-005 | 23222812 |
| 16858 | Neuroblastoma | 1.62e-005 | 23222812 |
| 16878 | Neuroblastoma | 1.62e-006 | 23222812 |
| 16903 | Neuroblastoma | 7.25e-013 | 23222812 |
| 16927 | Neuroblastoma | 2.93e-009 | 23222812 |
| 16931 | Neuroblastoma | 2.17e-009 | 23222812 |
| 16933 | Neuroblastoma | 1.21e-009 | 23222812 |
| 16948 | Neuroblastoma | 1.42e-006 | 23222812 |
| 16949 | Neuroblastoma | 3.73e-005 | 23222812 |
| 16950 | Neuroblastoma | 3.05e-013 | 23222812 |
| 16978 | Neuroblastoma | 2.84e-005 | 23222812 |
| 17006 | Neuroblastoma | 6.83e-005 | 23222812 |
| 17014 | Neuroblastoma | 1.35e-012 | 23222812 |
| 25636 | Coronary Artery Disease | 3.6410000E-005 | - |
| 25926 | Arteries | 5.8740000E-005 | - |
| 58876 | Myocardial Infarction | 3.3390000E-006 | - |
| 58883 | Myocardial Infarction | 4.2780000E-006 | - |
| 58884 | Myocardial Infarction | 4.4690000E-006 | - |
| 66045 | Neuroblastoma | 4E-14 | 22941191 |
| 91437 | Neuroblastoma | 5E-13 | 21124317 |
| 94691 | Neuroblastoma | 9E-18 | 19412175 |
GWAS
| ensgID | SNP | Chromosome | Position | Trait | PubmedID | Or or BEAT | EFO ID |
|---|
Protein-Protein Interaction (PPI)
Paralogs
| Ensembl ID | Source | Target | ||||||
|---|---|---|---|---|---|---|---|---|
| Species | Protein ID | Perc_pos | Perc_id | Species | Protein ID | Perc_pos | Perc_id | |
| ENSG00000138376 | ||||||||
Orthologs
| Ensembl ID | Source | Target | ||||||
|---|---|---|---|---|---|---|---|---|
| Species | Protein ID | Perc_pos | Perc_id | Species | Protein ID | Perc_pos | Perc_id | |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 98.713 | 97.8121 | nomascus_leucogenys | ENSNLEP00000008789 | 98.713 | 97.8121 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 99.8713 | 99.6139 | pan_paniscus | ENSPPAP00000041004 | 99.8713 | 99.6139 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 97.5547 | 96.3964 | pongo_abelii | ENSPPYP00000014687 | 96.8072 | 95.6577 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 99.7426 | 99.4852 | pan_troglodytes | ENSPTRP00000075471 | 99.7426 | 99.4852 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 99.2278 | 99.0991 | gorilla_gorilla | ENSGGOP00000031076 | 99.2278 | 99.0991 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 72.2008 | 57.0142 | ornithorhynchus_anatinus | ENSOANP00000049744 | 71.1929 | 56.2183 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 75.0322 | 61.5187 | sarcophilus_harrisii | ENSSHAP00000040225 | 72.2429 | 59.2317 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 64.3501 | 59.9743 | choloepus_hoffmanni | ENSCHOP00000004912 | 70.6215 | 65.8192 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 75.6757 | 66.9241 | dasypus_novemcinctus | ENSDNOP00000029986 | 80.9917 | 71.6253 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 58.9447 | 52.6384 | erinaceus_europaeus | ENSEEUP00000004965 | 74.9591 | 66.9394 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 80.5663 | 73.3591 | echinops_telfairi | ENSETEP00000008080 | 80.7742 | 73.5484 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 94.9807 | 91.8919 | callithrix_jacchus | ENSCJAP00000021140 | 86.5182 | 83.7046 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 97.6834 | 95.4955 | cercocebus_atys | ENSCATP00000040920 | 97.6834 | 95.4955 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 95.2381 | 93.0502 | macaca_fascicularis | ENSMFAP00000019223 | 97.6253 | 95.3826 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 97.6834 | 95.4955 | macaca_mulatta | ENSMMUP00000007521 | 97.6834 | 95.4955 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 97.2973 | 94.9807 | macaca_nemestrina | ENSMNEP00000038000 | 97.2973 | 94.9807 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 97.2973 | 95.2381 | papio_anubis | ENSPANP00000005319 | 97.2973 | 95.2381 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 93.1789 | 90.7336 | mandrillus_leucophaeus | ENSMLEP00000014808 | 95.3887 | 92.8854 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 89.0605 | 82.8829 | tursiops_truncatus | ENSTTRP00000007247 | 89.5213 | 83.3118 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 81.8533 | 76.0618 | vulpes_vulpes | ENSVVUP00000012347 | 88.4562 | 82.1975 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 81.4672 | 70.1416 | mus_spretus | MGP_SPRETEiJ_P0019177 | 82.7451 | 71.2418 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 90.0901 | 84.2986 | equus_asinus | ENSEASP00005019438 | 90.3226 | 84.5161 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 26.5122 | 23.8095 | capra_hircus | ENSCHIP00000015808 | 78.626 | 70.6107 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 88.1596 | 82.4968 | capra_hircus | ENSCHIP00000024535 | 88.3871 | 82.7097 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 87.0013 | 80.9524 | loxodonta_africana | ENSLAFP00000000460 | 87.1134 | 81.0567 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 89.8327 | 84.1699 | panthera_leo | ENSPLOP00000031142 | 90.2975 | 84.6054 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 88.5457 | 82.7542 | ailuropoda_melanoleuca | ENSAMEP00000004039 | 88.8889 | 83.0749 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 24.5817 | 21.7503 | bos_indicus_hybrid | ENSBIXP00005037127 | 87.2146 | 77.169 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 88.8031 | 83.1403 | bos_indicus_hybrid | ENSBIXP00005042408 | 89.2626 | 83.5705 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 84.9421 | 76.5766 | oryctolagus_cuniculus | ENSOCUP00000001334 | 87.8828 | 79.2277 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 89.8327 | 84.1699 | equus_caballus | ENSECAP00000054813 | 90.0645 | 84.3871 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 88.6744 | 81.982 | canis_lupus_familiaris | ENSCAFP00845028295 | 89.1332 | 82.4062 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 70.5277 | 66.0232 | canis_lupus_familiaris | ENSCAFP00845032518 | 87.9615 | 82.3435 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 89.704 | 84.1699 | panthera_pardus | ENSPPRP00000004977 | 90.1682 | 84.6054 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 82.6255 | 77.8636 | marmota_marmota_marmota | ENSMMMP00000018587 | 88.0658 | 82.9904 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 90.7336 | 86.2291 | balaenoptera_musculus | ENSBMSP00010004844 | 90.8505 | 86.3402 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 71.9434 | 64.4788 | cavia_porcellus | ENSCPOP00000010340 | 84.4411 | 75.6798 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 89.5753 | 83.9125 | felis_catus | ENSFCAP00000009574 | 90.0388 | 84.3467 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 89.5753 | 83.269 | ursus_americanus | ENSUAMP00000009297 | 89.2308 | 82.9487 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 74.26 | 61.0039 | monodelphis_domestica | ENSMODP00000019509 | 72.2153 | 59.3242 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 88.5457 | 82.8829 | bison_bison_bison | ENSBBBP00000001080 | 89.0039 | 83.3118 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 90.4762 | 84.2986 | monodon_monoceros | ENSMMNP00015010181 | 90.5928 | 84.4072 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 89.704 | 84.6847 | sus_scrofa | ENSSSCP00000069422 | 89.704 | 84.6847 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 89.5753 | 83.7838 | microcebus_murinus | ENSMICP00000035573 | 90.5071 | 84.6554 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 35.1351 | 31.7889 | octodon_degus | ENSODEP00000011039 | 90.3974 | 81.7881 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 36.2934 | 33.5907 | jaculus_jaculus | ENSJJAP00000012215 | 87.5776 | 81.0559 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 18.5328 | 17.6319 | ovis_aries_rambouillet | ENSOARP00020030628 | 91.7197 | 87.2611 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 17.5032 | 16.6023 | ovis_aries_rambouillet | ENSOARP00020017338 | 87.1795 | 82.6923 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 88.2883 | 82.3681 | ovis_aries_rambouillet | ENSOARP00020031151 | 88.5161 | 82.5806 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 84.0412 | 77.9923 | ursus_maritimus | ENSUMAP00000000975 | 88.3627 | 82.0027 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 67.6963 | 60.6178 | ochotona_princeps | ENSOPRP00000008308 | 67.9587 | 60.8527 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 90.4762 | 84.2986 | delphinapterus_leucas | ENSDLEP00000015278 | 90.5928 | 84.4072 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 90.8623 | 85.843 | physeter_catodon | ENSPCTP00005013319 | 90.9794 | 85.9536 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 81.2098 | 70.2703 | mus_caroli | MGP_CAROLIEiJ_P0018167 | 82.4837 | 71.3726 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 80.9524 | 69.7555 | mus_musculus | ENSMUSP00000027393 | 82.2222 | 70.8497 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 32.9472 | 30.2445 | dipodomys_ordii | ENSDORP00000024720 | 88.2759 | 81.0345 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 87.6448 | 81.4672 | mustela_putorius_furo | ENSMPUP00000007758 | 88.7875 | 82.5293 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 94.4659 | 92.0206 | aotus_nancymaae | ENSANAP00000018263 | 95.4486 | 92.9779 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 94.2085 | 91.3771 | saimiri_boliviensis_boliviensis | ENSSBOP00000016241 | 95.0649 | 92.2078 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 75.1609 | 69.7555 | vicugna_pacos | ENSVPAP00000003965 | 86.0088 | 79.8233 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 97.5547 | 95.6242 | chlorocebus_sabaeus | ENSCSAP00000005594 | 97.5547 | 95.6242 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 77.4775 | 71.8147 | tupaia_belangeri | ENSTBEP00000013429 | 77.7778 | 72.093 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 80.5663 | 70.7851 | mesocricetus_auratus | ENSMAUP00000004436 | 81.6167 | 71.708 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 89.9614 | 83.5264 | phocoena_sinus | ENSPSNP00000023944 | 87.4844 | 81.2265 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 84.0412 | 78.3784 | camelus_dromedarius | ENSCDRP00005014866 | 88.9646 | 82.97 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 33.3333 | 30.6306 | carlito_syrichta | ENSTSYP00000005611 | 87.2054 | 80.1347 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 84.556 | 78.8932 | panthera_tigris_altaica | ENSPTIP00000001024 | 90.1235 | 84.0878 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 80.695 | 68.8546 | rattus_norvegicus | ENSRNOP00000075183 | 81.6406 | 69.6615 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 88.9318 | 83.5264 | prolemur_simus | ENSPSMP00000002174 | 89.7403 | 84.2857 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 79.7941 | 69.7555 | microtus_ochrogaster | ENSMOCP00000019245 | 80.9399 | 70.7572 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 41.0553 | 35.2638 | sorex_araneus | ENSSARP00000011203 | 52.0392 | 44.6982 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 80.0515 | 70.2703 | peromyscus_maniculatus_bairdii | ENSPEMP00000007063 | 81.6273 | 71.6535 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 24.453 | 22.0077 | bos_mutus | ENSBMUP00000033156 | 86.758 | 78.0822 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 88.2883 | 82.4968 | bos_mutus | ENSBMUP00000030296 | 88.7451 | 82.9237 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 81.3385 | 69.8842 | mus_spicilegus | ENSMSIP00000038578 | 82.6144 | 70.9804 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 81.4672 | 71.686 | cricetulus_griseus_chok1gshd | ENSCGRP00001019904 | 82.5293 | 72.6206 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 89.9614 | 84.0412 | pteropus_vampyrus | ENSPVAP00000002162 | 90.0773 | 84.1495 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 80.9524 | 74.3887 | myotis_lucifugus | ENSMLUP00000012866 | 86.2826 | 79.2867 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 70.5277 | 57.7864 | vombatus_ursinus | ENSVURP00010004162 | 74.7613 | 61.2551 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 86.7439 | 79.7941 | rhinolophus_ferrumequinum | ENSRFEP00010025664 | 86.6324 | 79.6915 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 87.2587 | 80.9524 | neovison_vison | ENSNVIP00000012600 | 88.2812 | 81.901 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 24.453 | 21.7503 | bos_taurus | ENSBTAP00000073969 | 86.758 | 77.169 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 88.8031 | 83.0116 | bos_taurus | ENSBTAP00000045022 | 89.2626 | 83.4411 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 87.2587 | 79.2793 | heterocephalus_glaber_female | ENSHGLP00000035221 | 84.3284 | 76.6169 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 96.6538 | 94.5946 | rhinopithecus_bieti | ENSRBIP00000040308 | 97.406 | 95.3307 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 33.7194 | 31.5315 | canis_lupus_dingo | ENSCAFP00020009843 | 85.9016 | 80.3279 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 88.6744 | 81.982 | canis_lupus_dingo | ENSCAFP00020035253 | 88.5604 | 81.8766 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 88.417 | 82.4968 | sciurus_vulgaris | ENSSVLP00005009306 | 88.6452 | 82.7097 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 75.4183 | 62.2909 | phascolarctos_cinereus | ENSPCIP00000030369 | 72.9763 | 60.274 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 66.1519 | 57.6577 | procavia_capensis | ENSPCAP00000014180 | 78.2344 | 68.1887 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 80.695 | 69.6268 | nannospalax_galili | ENSNGAP00000026102 | 84.0483 | 72.5201 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 88.2883 | 82.4968 | bos_grunniens | ENSBGRP00000005598 | 88.7451 | 82.9237 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 86.3578 | 79.2793 | chinchilla_lanigera | ENSCLAP00000011077 | 87.0298 | 79.8962 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 37.9665 | 36.036 | cervus_hanglu_yarkandensis | ENSCHYP00000006013 | 91.9003 | 87.2274 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 89.9614 | 84.0412 | catagonus_wagneri | ENSCWAP00000012963 | 90.1936 | 84.2581 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 87.7735 | 82.6255 | ictidomys_tridecemlineatus | ENSSTOP00000002162 | 87.8866 | 82.732 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 84.1699 | 75.0322 | otolemur_garnettii | ENSOGAP00000008142 | 84.6054 | 75.4204 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 95.3668 | 92.1493 | cebus_imitator | ENSCCAP00000006910 | 95.2442 | 92.0308 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 88.0309 | 82.7542 | urocitellus_parryii | ENSUPAP00010005272 | 88.1443 | 82.8608 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 89.1892 | 81.8533 | moschus_moschiferus | ENSMMSP00000029183 | 89.4194 | 82.0645 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 94.2085 | 92.1493 | rhinopithecus_roxellana | ENSRROP00000008021 | 97.3404 | 95.2128 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 81.2098 | 70.399 | mus_pahari | MGP_PahariEiJ_P0073475 | 82.5916 | 71.5969 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 89.4466 | 83.5264 | propithecus_coquereli | ENSPCOP00000000639 | 90.3771 | 84.3953 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 24.0669 | 13.5135 | caenorhabditis_elegans | T16G1.9.1 | 19.7884 | 11.1111 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 39.1248 | 20.9781 | drosophila_melanogaster | FBpp0312411 | 21.637 | 11.6014 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 26.3835 | 14.5431 | ciona_intestinalis | ENSCINP00000028343 | 40.275 | 22.2004 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 35.2638 | 24.0669 | petromyzon_marinus | ENSPMAP00000010442 | 49.2806 | 33.6331 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 47.619 | 34.8777 | eptatretus_burgeri | ENSEBUP00000012633 | 51.2465 | 37.5346 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 45.9459 | 34.8777 | callorhinchus_milii | ENSCMIP00000041428 | 59.3023 | 45.0166 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 64.2214 | 48.7773 | latimeria_chalumnae | ENSLACP00000022324 | 57.6212 | 43.7644 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 50.5792 | 36.1647 | lepisosteus_oculatus | ENSLOCP00000005344 | 47.6364 | 34.0606 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 52.5097 | 37.1943 | clupea_harengus | ENSCHAP00000062146 | 52.1073 | 36.9093 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 43.3719 | 29.7297 | danio_rerio | ENSDARP00000146363 | 49.0539 | 33.6245 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 30.888 | 20.8494 | carassius_auratus | ENSCARP00000053532 | 46.6019 | 31.4563 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 13.2561 | 9.26641 | carassius_auratus | ENSCARP00000059506 | 72.028 | 50.3497 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 11.9691 | 9.13771 | carassius_auratus | ENSCARP00000053548 | 68.8889 | 52.5926 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 52.1236 | 37.5804 | astyanax_mexicanus | ENSAMXP00000019457 | 50.625 | 36.5 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 51.4801 | 37.4517 | ictalurus_punctatus | ENSIPUP00000011755 | 54.8697 | 39.9177 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 51.7375 | 36.9369 | esox_lucius | ENSELUP00000007718 | 49.691 | 35.4759 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 42.471 | 30.888 | electrophorus_electricus | ENSEEEP00000049245 | 47.8955 | 34.8331 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 53.9254 | 37.1943 | oncorhynchus_kisutch | ENSOKIP00005047287 | 49.9404 | 34.4458 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 52.5097 | 36.036 | oncorhynchus_mykiss | ENSOMYP00000048154 | 46.1538 | 31.6742 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 53.5393 | 36.9369 | salmo_salar | ENSSSAP00000168812 | 49.5238 | 34.1667 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 53.7967 | 37.1943 | salmo_trutta | ENSSTUP00000113679 | 50.8516 | 35.1581 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 48.3912 | 33.7194 | gadus_morhua | ENSGMOP00000047992 | 48.2051 | 33.5897 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 13.2561 | 10.5534 | fundulus_heteroclitus | ENSFHEP00000020152 | 70.5479 | 56.1644 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 47.2329 | 34.749 | poecilia_reticulata | ENSPREP00000017694 | 50.831 | 37.3961 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 53.1532 | 38.3526 | xiphophorus_maculatus | ENSXMAP00000039651 | 51.625 | 37.25 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 52.8958 | 36.9369 | oryzias_latipes | ENSORLP00000020088 | 51.5038 | 35.9649 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 42.8571 | 30.888 | cyclopterus_lumpus | ENSCLMP00005049096 | 50 | 36.036 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 54.6976 | 38.3526 | oreochromis_niloticus | ENSONIP00000005289 | 52.3399 | 36.6995 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 54.4402 | 38.4813 | haplochromis_burtoni | ENSHBUP00000000997 | 52.0295 | 36.7774 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 54.1828 | 38.4813 | astatotilapia_calliptera | ENSACLP00000027401 | 51.7835 | 36.7774 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 52.2523 | 38.0952 | sparus_aurata | ENSSAUP00010009748 | 50.8772 | 37.0927 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 54.1828 | 37.9665 | lates_calcarifer | ENSLCAP00010043080 | 51.7199 | 36.2408 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 58.816 | 44.0154 | xenopus_tropicalis | ENSXETP00000031175 | 61.8403 | 46.2788 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 17.3745 | 14.2857 | chrysemys_picta_bellii | ENSCPBP00000006227 | 78.9474 | 64.9123 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 46.7181 | 33.7194 | chrysemys_picta_bellii | ENSCPBP00000016034 | 55.3354 | 39.939 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 12.9987 | 10.6821 | sphenodon_punctatus | ENSSPUP00000013161 | 77.6923 | 63.8462 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 20.8494 | 16.8597 | sphenodon_punctatus | ENSSPUP00000013144 | 73.9726 | 59.8174 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 66.0232 | 51.6088 | crocodylus_porosus | ENSCPRP00005004585 | 64.691 | 50.5675 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 15.1866 | 13.2561 | laticauda_laticaudata | ENSLLTP00000015300 | 73.2919 | 63.9752 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 23.166 | 15.444 | laticauda_laticaudata | ENSLLTP00000012203 | 38.7931 | 25.8621 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 25.9974 | 21.1068 | notechis_scutatus | ENSNSUP00000005170 | 64.9518 | 52.7331 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 25.9974 | 20.9781 | pseudonaja_textilis | ENSPTXP00000010058 | 62.9283 | 50.7788 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 65.251 | 51.7375 | anas_platyrhynchos_platyrhynchos | ENSAPLP00000015447 | 64.2586 | 50.9506 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 66.1519 | 51.4801 | gallus_gallus | ENSGALP00010016369 | 63.3785 | 49.3218 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 65.1223 | 50.0644 | meleagris_gallopavo | ENSMGAP00000003378 | 67.3768 | 51.7976 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 66.1519 | 50.9653 | serinus_canaria | ENSSCAP00000005677 | 65.2284 | 50.2538 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 66.7954 | 51.7375 | parus_major | ENSPMJP00000008533 | 65.8629 | 51.0152 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 61.1326 | 46.8468 | anolis_carolinensis | ENSACAP00000015187 | 61.7685 | 47.3342 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 13.3848 | 10.1673 | neolamprologus_brichardi | ENSNBRP00000002816 | 68.4211 | 51.9737 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 57.1429 | 42.9858 | naja_naja | ENSNNAP00000005894 | 57.2165 | 43.0412 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 55.2124 | 40.6692 | podarcis_muralis | ENSPMRP00000006971 | 61.4613 | 45.2722 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 26.7696 | 20.7207 | geospiza_fortis | ENSGFOP00000019659 | 74.2857 | 57.5 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 26.8983 | 19.1763 | geospiza_fortis | ENSGFOP00000019654 | 51.9901 | 37.0647 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 66.4093 | 51.2227 | taeniopygia_guttata | ENSTGUP00000002986 | 65.6489 | 50.6361 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 41.6988 | 30.5019 | erpetoichthys_calabaricus | ENSECRP00000020931 | 59.5588 | 43.5662 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 54.1828 | 37.4517 | kryptolebias_marmoratus | ENSKMAP00000028123 | 52.4938 | 36.2843 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 62.2909 | 45.9459 | salvator_merianae | ENSSMRP00000026980 | 57.0082 | 42.0495 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 53.668 | 37.4517 | oryzias_javanicus | ENSOJAP00000048990 | 51.9303 | 36.2391 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 12.9987 | 10.1673 | amphilophus_citrinellus | ENSACIP00000016906 | 68.7075 | 53.7415 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 44.0154 | 31.7889 | dicentrarchus_labrax | ENSDLAP00005017132 | 51.0448 | 36.8657 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 41.9562 | 30.5019 | amphiprion_percula | ENSAPEP00000020029 | 47.8708 | 34.8018 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 52.7671 | 36.9369 | oryzias_sinensis | ENSOSIP00000016340 | 51.1222 | 35.7855 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 59.8456 | 47.2329 | pelodiscus_sinensis | ENSPSIP00000017188 | 67.2938 | 53.1114 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 63.5779 | 50.0644 | gopherus_evgoodei | ENSGEVP00005020290 | 66.3087 | 52.2148 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 65.3797 | 50.9653 | chelonoidis_abingdonii | ENSCABP00000024563 | 67.9144 | 52.9412 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 54.3115 | 38.4813 | seriola_dumerili | ENSSDUP00000019914 | 52.1632 | 36.9592 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 54.0541 | 39.2535 | cottoperca_gobio | ENSCGOP00000040105 | 52.0446 | 37.7943 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 57.4003 | 43.8867 | struthio_camelus_australis | ENSSCUP00000018062 | 65.3001 | 49.9268 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 64.3501 | 51.094 | anser_brachyrhynchus | ENSABRP00000025685 | 65.6168 | 52.0997 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 19.1763 | 14.0283 | gasterosteus_aculeatus | ENSGACP00000008581 | 66.2222 | 48.4444 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 52.2523 | 37.7091 | cynoglossus_semilaevis | ENSCSEP00000018533 | 51.0692 | 36.8553 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 52.381 | 38.2239 | poecilia_formosa | ENSPFOP00000005078 | 54.6309 | 39.8658 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 53.7967 | 38.3526 | myripristis_murdjan | ENSMMDP00005047149 | 51.9255 | 37.0186 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 52.6384 | 37.5804 | sander_lucioperca | ENSSLUP00000022667 | 52.6384 | 37.5804 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 56.242 | 41.3127 | strigops_habroptila | ENSSHBP00005000695 | 57.2739 | 42.0708 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 16.0875 | 13.3848 | strigops_habroptila | ENSSHBP00005000696 | 80.1282 | 66.6667 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 55.3411 | 38.61 | amphiprion_ocellaris | ENSAOCP00000008446 | 46.6377 | 32.538 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 63.5779 | 49.5495 | terrapene_carolina_triunguis | ENSTMTP00000004002 | 66.5768 | 51.8868 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 53.4106 | 36.9369 | hucho_hucho | ENSHHUP00000018646 | 50.7335 | 35.0856 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 53.9254 | 37.0656 | betta_splendens | ENSBSLP00000044199 | 53.5121 | 36.7816 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 52.2523 | 38.7387 | pygocentrus_nattereri | ENSPNAP00000007735 | 50.6234 | 37.5312 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 54.955 | 39.5109 | anabas_testudineus | ENSATEP00000000537 | 52.7812 | 37.9481 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 31.4028 | 21.1068 | ciona_savignyi | ENSCSAVP00000002316 | 52.8139 | 35.4978 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 46.9755 | 32.175 | seriola_lalandi_dorsalis | ENSSLDP00000012047 | 47.4026 | 32.4675 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 54.1828 | 39.3822 | labrus_bergylta | ENSLBEP00000003318 | 52.4938 | 38.1546 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 45.1737 | 32.9472 | pundamilia_nyererei | ENSPNYP00000025440 | 54.7582 | 39.9376 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 53.7967 | 36.8082 | mastacembelus_armatus | ENSMAMP00000028156 | 52.3154 | 35.7947 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 55.0837 | 39.3822 | stegastes_partitus | ENSSPAP00000005852 | 52.5799 | 37.5921 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 54.1828 | 37.4517 | oncorhynchus_tshawytscha | ENSOTSP00005041193 | 50.8454 | 35.1449 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 55.2124 | 39.2535 | acanthochromis_polyacanthus | ENSAPOP00000011589 | 52.5735 | 37.3775 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 55.9846 | 42.9858 | aquila_chrysaetos_chrysaetos | ENSACCP00020022178 | 65.2174 | 50.075 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 52.6384 | 36.6795 | nothobranchius_furzeri | ENSNFUP00015054524 | 52.4359 | 36.5385 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 52.6384 | 38.4813 | cyprinodon_variegatus | ENSCVAP00000013624 | 50.184 | 36.6871 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 23.9382 | 16.4736 | denticeps_clupeoides | ENSDCDP00000054113 | 46.9697 | 32.3232 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 13.8996 | 11.0682 | denticeps_clupeoides | ENSDCDP00000054111 | 67.9245 | 54.0881 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 51.2227 | 36.4221 | larimichthys_crocea | ENSLCRP00005058460 | 52.0261 | 36.9935 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 52.381 | 36.4221 | takifugu_rubripes | ENSTRUP00000037470 | 51.4539 | 35.7775 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 59.9743 | 45.8172 | ficedula_albicollis | ENSFALP00000013492 | 66.0993 | 50.4965 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 53.2819 | 37.4517 | hippocampus_comes | ENSHCOP00000006973 | 52.8736 | 37.1647 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 13.6422 | 9.78121 | cyprinus_carpio_carpio | ENSCCRP00000081573 | 72.1088 | 51.7007 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 41.184 | 29.3436 | cyprinus_carpio_carpio | ENSCCRP00000125786 | 51.7799 | 36.8932 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 65.3797 | 49.9356 | coturnix_japonica | ENSCJPP00005017132 | 65.6331 | 50.1292 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 37.8378 | 26.1261 | poecilia_latipinna | ENSPLAP00000025950 | 46.1538 | 31.8681 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 13.3848 | 10.9395 | poecilia_latipinna | ENSPLAP00000028929 | 70.7483 | 57.8231 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 9.65251 | 6.82111 | sinocyclocheilus_grahami | ENSSGRP00000091406 | 73.5294 | 51.9608 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 13.1274 | 9.39511 | sinocyclocheilus_grahami | ENSSGRP00000030630 | 75.5556 | 54.0741 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 44.6589 | 30.7593 | maylandia_zebra | ENSMZEP00005013356 | 48.6676 | 33.5203 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 50.4505 | 34.2342 | tetraodon_nigroviridis | ENSTNIP00000019537 | 54.3689 | 36.8932 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 51.7375 | 36.4221 | paramormyrops_kingsleyae | ENSPKIP00000008335 | 52.9644 | 37.2859 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 20.8494 | 15.0579 | scleropages_formosus | ENSSFOP00015027582 | 57.8571 | 41.7857 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 54.3115 | 38.3526 | scophthalmus_maximus | ENSSMAP00000014845 | 51.7157 | 36.5196 |
| ENSG00000138376 | homo_sapiens | ENSP00000260947 | 53.5393 | 37.8378 | oryzias_melastigma | ENSOMEP00000000518 | 51.7413 | 36.5672 |
Gene Ontology
| Go ID | Go term | No. evidence | Entries | Species | Category |
|---|---|---|---|---|---|
| GO:0000151 | part_of ubiquitin ligase complex | 1 | NAS | Homo_sapiens(9606) | Component |
| GO:0000152 | part_of nuclear ubiquitin ligase complex | 1 | IDA | Homo_sapiens(9606) | Component |
| GO:0000209 | involved_in protein polyubiquitination | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0001894 | involved_in tissue homeostasis | 1 | TAS | Homo_sapiens(9606) | Process |
| GO:0003723 | enables RNA binding | 1 | IDA | Homo_sapiens(9606) | Function |
| GO:0004842 | contributes_to ubiquitin-protein transferase activity | 3 | IBA,IDA,NAS | Homo_sapiens(9606) | Function |
| GO:0005515 | enables protein binding | 1 | IPI | Homo_sapiens(9606) | Function |
| GO:0005634 | located_in nucleus | 3 | IDA,IMP,NAS | Homo_sapiens(9606) | Component |
| GO:0005654 | located_in nucleoplasm | 2 | IDA,TAS | Homo_sapiens(9606) | Component |
| GO:0005737 | located_in cytoplasm | 1 | IDA | Homo_sapiens(9606) | Component |
| GO:0006281 | involved_in DNA repair | 1 | NAS | Homo_sapiens(9606) | Process |
| GO:0006282 | involved_in regulation of DNA repair | 1 | NAS | Homo_sapiens(9606) | Process |
| GO:0006974 | involved_in DNA damage response | 1 | NAS | Homo_sapiens(9606) | Process |
| GO:0016567 | involved_in protein ubiquitination | 1 | NAS | Homo_sapiens(9606) | Process |
| GO:0016607 | located_in nuclear speck | 1 | IDA | Homo_sapiens(9606) | Component |
| GO:0019900 | enables kinase binding | 1 | NAS | Homo_sapiens(9606) | Function |
| GO:0031436 | part_of BRCA1-BARD1 complex | 3 | IBA,IDA,IPI | Homo_sapiens(9606) | Component |
| GO:0031441 | involved_in negative regulation of mRNA 3-end processing | 1 | NAS | Homo_sapiens(9606) | Process |
| GO:0035518 | involved_in histone H2A monoubiquitination | 1 | NAS | Homo_sapiens(9606) | Process |
| GO:0035825 | involved_in homologous recombination | 1 | NAS | Homo_sapiens(9606) | Process |
| GO:0036464 | located_in cytoplasmic ribonucleoprotein granule | 1 | IDA | Homo_sapiens(9606) | Component |
| GO:0042325 | involved_in regulation of phosphorylation | 1 | IMP | Homo_sapiens(9606) | Process |
| GO:0042803 | enables protein homodimerization activity | 1 | IPI | Homo_sapiens(9606) | Function |
| GO:0043065 | involved_in positive regulation of apoptotic process | 1 | IMP | Homo_sapiens(9606) | Process |
| GO:0043066 | involved_in negative regulation of apoptotic process | 1 | IMP | Homo_sapiens(9606) | Process |
| GO:0044818 | involved_in mitotic G2/M transition checkpoint | 1 | NAS | Homo_sapiens(9606) | Process |
| GO:0045732 | involved_in positive regulation of protein catabolic process | 1 | NAS | Homo_sapiens(9606) | Process |
| GO:0045786 | involved_in negative regulation of cell cycle | 1 | NAS | Homo_sapiens(9606) | Process |
| GO:0046826 | involved_in negative regulation of protein export from nucleus | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0046872 | enables metal ion binding | 1 | IEA | Homo_sapiens(9606) | Function |
| GO:0046982 | enables protein heterodimerization activity | 1 | IPI | Homo_sapiens(9606) | Function |
| GO:0051726 | involved_in regulation of cell cycle | 1 | NAS | Homo_sapiens(9606) | Process |
| GO:0051865 | involved_in protein autoubiquitination | 1 | NAS | Homo_sapiens(9606) | Process |
| GO:0070531 | part_of BRCA1-A complex | 3 | IBA,IDA,NAS | Homo_sapiens(9606) | Component |
| GO:0070532 | part_of BRCA1-B complex | 1 | IPI | Homo_sapiens(9606) | Component |
| GO:0070533 | part_of BRCA1-C complex | 1 | IPI | Homo_sapiens(9606) | Component |
| GO:0070537 | involved_in histone H2A K63-linked deubiquitination | 1 | NAS | Homo_sapiens(9606) | Process |
| GO:0071479 | involved_in cellular response to ionizing radiation | 1 | IMP | Homo_sapiens(9606) | Process |
| GO:0085020 | involved_in protein K6-linked ubiquitination | 2 | IBA,IDA | Homo_sapiens(9606) | Process |
| GO:0110025 | involved_in DNA strand resection involved in replication fork processing | 1 | NAS | Homo_sapiens(9606) | Process |
| GO:2000001 | involved_in regulation of DNA damage checkpoint | 1 | NAS | Homo_sapiens(9606) | Process |