RBP Type	Non-canonical_RBPs
Diseases	Disease
Drug	Drug
Main interacting RNAs	N.A.
Moonlighting functions	Kinase
Localizations	N.A.
BulkPerturb-seq

Ensembl ID	ENSG00000137948	Gene ID	676	Accession	1105
Symbol	BRDT	Alias	CT9;BRD6;SPGF21	Full Name	bromodomain testis associated
Status	Confidence	Length	65084 bases	Strand	Plus strand
Position	1 : 91949343 - 92014426	RNA binding domain	N.A.
Summary	BRDT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence (a cluster of proline, glutamic acid, serine, and threonine residues), characteristic of proteins that undergo rapid intracellular degradation. The bromodomain is found in proteins that regulate transcription. Several transcript variants encoding multiple isoforms have been found for this gene. [provided by RefSeq, Jun 2011]

Protein	Domain	Pfam ID	E-value	Domain number

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal
30558232	Targeting the Oncoprotein Smoothened by Small Molecules: Focus on Novel Acylguanidine Derivatives as Potent Smoothened Inhibitors.	Silvia Pietrobono	2018-12-14	Cells
33469999	Genome-wide chromatin occupancy of BRDT and gene expression analysis suggest transcriptional partners and specific epigenetic landscapes that regulate gene expression during spermatogenesis.	Ra Yoon Her	2021-02-01	Molecular reproduction and development

Name	Transcript ID	bp	Protein	Translation ID
BRDT-211	ENST00000448194	1482	238aa	ENSP00000410587
BRDT-216	ENST00000470955	998	71aa	ENSP00000506247
BRDT-202	ENST00000362005	3409	947aa	ENSP00000354568
BRDT-203	ENST00000370389	3696	874aa	ENSP00000359416
BRDT-204	ENST00000394530	3207	901aa	ENSP00000378038
BRDT-207	ENST00000423434	760	176aa	ENSP00000396351
BRDT-210	ENST00000440509	788	200aa	ENSP00000416714
BRDT-208	ENST00000426141	1530	462aa	ENSP00000404969
BRDT-215	ENST00000461218	567	No protein	-
BRDT-217	ENST00000476711	579	No protein	-
BRDT-212	ENST00000449584	550	52aa	ENSP00000408625
BRDT-209	ENST00000427104	1363	155aa	ENSP00000400002
BRDT-201	ENST00000355011	534	14aa	ENSP00000400199
BRDT-205	ENST00000399546	3310	947aa	ENSP00000387822
BRDT-219	ENST00000484833	585	No protein	-
BRDT-213	ENST00000450792	559	96aa	ENSP00000414349
BRDT-220	ENST00000548992	569	100aa	ENSP00000447394
BRDT-221	ENST00000552654	578	63aa	ENSP00000446599
BRDT-214	ENST00000457265	551	31aa	ENSP00000408138
BRDT-206	ENST00000402388	3125	947aa	ENSP00000384051
BRDT-224	ENST00000680541	1153	345aa	ENSP00000505035
BRDT-222	ENST00000680091	1563	475aa	ENSP00000506227
BRDT-218	ENST00000484781	604	No protein	-
BRDT-223	ENST00000680194	1001	251aa	ENSP00000506530

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0003713	enables transcription coactivator activity	1	TAS	Homo_sapiens(9606)	Function
GO:0005634	located_in nucleus	2	IDA,ISS	Homo_sapiens(9606)	Component
GO:0006338	involved_in chromatin remodeling	1	ISS	Homo_sapiens(9606)	Process
GO:0006355	involved_in regulation of DNA-templated transcription	1	IMP	Homo_sapiens(9606)	Process
GO:0006397	involved_in mRNA processing	1	IEA	Homo_sapiens(9606)	Process
GO:0007140	involved_in male meiotic nuclear division	1	ISS	Homo_sapiens(9606)	Process
GO:0007141	involved_in male meiosis I	1	ISS	Homo_sapiens(9606)	Process
GO:0008380	involved_in RNA splicing	1	IEA	Homo_sapiens(9606)	Process
GO:0035092	involved_in sperm DNA condensation	1	ISS	Homo_sapiens(9606)	Process
GO:0042393	enables histone binding	1	IDA	Homo_sapiens(9606)	Function
GO:0043484	involved_in regulation of RNA splicing	1	ISS	Homo_sapiens(9606)	Process
GO:0051039	involved_in positive regulation of transcription involved in meiotic cell cycle	1	ISS	Homo_sapiens(9606)	Process
GO:0070577	enables lysine-acetylated histone binding	1	ISS	Homo_sapiens(9606)	Function
GO:0140566	enables histone reader activity	1	ISS	Homo_sapiens(9606)	Function