Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases Cancer Disease
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions N.A.
Localizations P-body
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000137497 Gene ID 4926 Accession 8059
Symbol NUMA1 Alias NUMA;NMP-22 Full Name nuclear mitotic apparatus protein 1
Status Confidence Length 77830 bases Strand Minus strand
Position 11 : 72002864 - 72080693 RNA binding domain N.A.
Summary This gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
34244513 Multiplexed functional genomic analysis of 5' untranslated region mutations across the spectrum of prostate cancer. Yiting Lim 2021-07-09 Nature communications

Transcripts

Name Transcript ID bp Protein Translation ID
NUMA1-217 ENST00000540626 2276 No protein -
NUMA1-220 ENST00000541584 3557 964aa ENSP00000440954
NUMA1-201 ENST00000351960 3775 979aa ENSP00000260051
NUMA1-202 ENST00000358965 7227 2101aa ENSP00000351851
NUMA1-205 ENST00000393695 7198 2115aa ENSP00000377298
NUMA1-233 ENST00000620566 7012 2101aa ENSP00000478624
NUMA1-232 ENST00000613205 3940 979aa ENSP00000480172
NUMA1-219 ENST00000541262 706 No protein -
NUMA1-229 ENST00000545721 2796 353aa ENSP00000446396
NUMA1-230 ENST00000546036 592 No protein -
NUMA1-216 ENST00000540588 216 No protein -
NUMA1-223 ENST00000542977 2766 851aa ENSP00000444880
NUMA1-213 ENST00000537217 2331 691aa ENSP00000442936
NUMA1-207 ENST00000534987 2211 No protein -
NUMA1-218 ENST00000540843 1969 No protein -
NUMA1-212 ENST00000536119 1686 No protein -
NUMA1-228 ENST00000544238 792 220aa ENSP00000442761
NUMA1-226 ENST00000543937 911 201aa ENSP00000439759
NUMA1-224 ENST00000543009 874 174aa ENSP00000438821
NUMA1-215 ENST00000537930 582 159aa ENSP00000438589
NUMA1-227 ENST00000544129 600 159aa ENSP00000439092
NUMA1-211 ENST00000535947 576 146aa ENSP00000444175
NUMA1-206 ENST00000534971 878 No protein -
NUMA1-208 ENST00000535087 606 109aa ENSP00000439576
NUMA1-204 ENST00000368959 583 91aa ENSP00000357955
NUMA1-222 ENST00000541719 583 82aa ENSP00000438331
NUMA1-203 ENST00000366394 539 75aa ENSP00000438318
NUMA1-221 ENST00000541641 589 72aa ENSP00000441598
NUMA1-214 ENST00000537905 598 No protein -
NUMA1-209 ENST00000535111 582 61aa ENSP00000441674
NUMA1-210 ENST00000535838 582 59aa ENSP00000444831
NUMA1-231 ENST00000546131 280 56aa ENSP00000442331
NUMA1-225 ENST00000543450 3339 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
34526Platelet Function Tests3.8612500E-005-
78356Influenza A Virus, H1N1 Subtype8E-1726379185
94399Serologic Tests8E-725758998
94400Chlamydial Pneumonia8E-725758998

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000137497homo_sapiensENSP0000027893531.232913.6301homo_sapiensENSP0000037729821.56039.40898
ENSG00000137497homo_sapiensENSP0000041037841.188320.761homo_sapiensENSP0000037729829.172614.7045
ENSG00000137497homo_sapiensENSP0000030793936.579616.152homo_sapiensENSP0000037729829.125312.8605

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000137497homo_sapiensENSP0000037729843.215142.6005nomascus_leucogenysENSNLEP0000002095396.515395.1426
ENSG00000137497homo_sapiensENSP0000037729899.527299.2908pan_paniscusENSPPAP0000001483899.527299.2908
ENSG00000137497homo_sapiensENSP0000037729899.196298.2979pongo_abeliiENSPPYP0000002448999.243198.3444
ENSG00000137497homo_sapiensENSP0000037729899.479999.2908pan_troglodytesENSPTRP0000009370099.668499.4789
ENSG00000137497homo_sapiensENSP0000037729899.527299.1962gorilla_gorillaENSGGOP0000004697899.527299.1962
ENSG00000137497homo_sapiensENSP0000037729827.139521.7021ornithorhynchus_anatinusENSOANP0000000094277.150561.6936
ENSG00000137497homo_sapiensENSP0000037729878.723465.9102sarcophilus_harrisiiENSSHAP0000002974280.318467.2455
ENSG00000137497homo_sapiensENSP0000037729865.342854.6572notamacropus_eugeniiENSMEUP0000000395668.927757.6559
ENSG00000137497homo_sapiensENSP0000037729865.295560.9929choloepus_hoffmanniENSCHOP0000000418466.23561.8705
ENSG00000137497homo_sapiensENSP0000037729893.853487.896dasypus_novemcinctusENSDNOP0000000924593.455787.5235
ENSG00000137497homo_sapiensENSP0000037729850.023645.3901erinaceus_europaeusENSEEUP0000000351350.573645.8891
ENSG00000137497homo_sapiensENSP0000037729877.494170.9693echinops_telfairiENSETEP0000001462987.273779.9255
ENSG00000137497homo_sapiensENSP0000037729897.257794.5626callithrix_jacchusENSCJAP0000007523996.076693.4143
ENSG00000137497homo_sapiensENSP0000037729891.205785.5792cercocebus_atysENSCATP0000004393191.944786.2726
ENSG00000137497homo_sapiensENSP0000037729898.865297.2104macaca_fascicularisENSMFAP0000003175598.725297.0727
ENSG00000137497homo_sapiensENSP0000037729897.494195.6028macaca_mulattaENSMMUP0000007059195.728993.8719
ENSG00000137497homo_sapiensENSP0000037729897.399595.5556macaca_nemestrinaENSMNEP0000000308695.63693.8254
ENSG00000137497homo_sapiensENSP0000037729897.541495.6501papio_anubisENSPANP0000006055695.775393.9183
ENSG00000137497homo_sapiensENSP0000037729897.446895.5083papio_anubisENSPANP0000003450192.629290.7865
ENSG00000137497homo_sapiensENSP0000037729898.061596.2648mandrillus_leucophaeusENSMLEP0000001156197.508295.7217
ENSG00000137497homo_sapiensENSP0000037729890.685685.4374tursiops_truncatusENSTTRP0000000370790.771485.5182
ENSG00000137497homo_sapiensENSP0000037729894.137188.9835vulpes_vulpesENSVVUP0000003562192.475687.4129
ENSG00000137497homo_sapiensENSP0000037729889.692782.0331mus_spretusMGP_SPRETEiJ_P008443190.592282.8558
ENSG00000137497homo_sapiensENSP0000037729895.1390.6856equus_asinusENSEASP0000500070294.771690.3439
ENSG00000137497homo_sapiensENSP0000037729892.245986.2411capra_hircusENSCHIP0000000359192.245986.2411
ENSG00000137497homo_sapiensENSP0000037729891.631286.6194loxodonta_africanaENSLAFP0000000469391.458286.4559
ENSG00000137497homo_sapiensENSP0000037729894.751889.7872panthera_leoENSPLOP0000001772993.864288.9461
ENSG00000137497homo_sapiensENSP0000037729894.704589.5035ailuropoda_melanoleucaENSAMEP0000003956392.602987.5173
ENSG00000137497homo_sapiensENSP0000037729892.529586.4303bos_indicus_hybridENSBIXP0000502247992.180986.1046
ENSG00000137497homo_sapiensENSP0000037729892.529587.4232oryctolagus_cuniculusENSOCUP0000002508592.485887.3819
ENSG00000137497homo_sapiensENSP0000037729894.893690.4019equus_caballusENSECAP0000006973992.873788.4776
ENSG00000137497homo_sapiensENSP0000037729894.515489.4563canis_lupus_familiarisENSCAFP0084501489194.515489.4563
ENSG00000137497homo_sapiensENSP0000037729894.799189.9291panthera_pardusENSPPRP0000000200594.754289.8866
ENSG00000137497homo_sapiensENSP0000037729893.380688.3215marmota_marmota_marmotaENSMMMP0000001359293.557688.4889
ENSG00000137497homo_sapiensENSP0000037729895.1389.9764balaenoptera_musculusENSBMSP0001002729895.040289.8914
ENSG00000137497homo_sapiensENSP0000037729890.780184.2553cavia_porcellusENSCPOP0000000795590.694484.1757
ENSG00000137497homo_sapiensENSP0000037729894.609989.6927felis_catusENSFCAP0000006016793.723788.8525
ENSG00000137497homo_sapiensENSP0000037729876.075771.8203ursus_americanusENSUAMP0000003606194.038688.7785
ENSG00000137497homo_sapiensENSP0000037729811.394810.9693ursus_americanusENSUAMP0000003607893.410989.9225
ENSG00000137497homo_sapiensENSP0000037729878.48765.0118monodelphis_domesticaENSMODP0000001011179.198565.6011
ENSG00000137497homo_sapiensENSP0000037729892.529586.2884bison_bison_bisonENSBBBP0000000372892.573386.3292
ENSG00000137497homo_sapiensENSP0000037729894.27988.9835monodon_monocerosENSMMNP0001502585991.551986.4096
ENSG00000137497homo_sapiensENSP0000037729892.43586.5721sus_scrofaENSSSCP0000003291890.88885.1232
ENSG00000137497homo_sapiensENSP0000037729894.751890.6856microcebus_murinusENSMICP0000003594094.662390.5999
ENSG00000137497homo_sapiensENSP0000037729810.44929.64539octodon_degusENSODEP0000002487687.007980.315
ENSG00000137497homo_sapiensENSP0000037729890.212883.3097octodon_degusENSODEP0000001056490.813983.8648
ENSG00000137497homo_sapiensENSP0000037729892.198685.7683jaculus_jaculusENSJJAP0000001784791.463485.0844
ENSG00000137497homo_sapiensENSP0000037729892.387786.4303ovis_aries_rambouilletENSOARP0002002121592.387786.4303
ENSG00000137497homo_sapiensENSP0000037729893.049687.7541ursus_maritimusENSUMAP0000000990991.833986.6076
ENSG00000137497homo_sapiensENSP0000037729887.89681.3712ochotona_princepsENSOPRP0000001309288.650582.0696
ENSG00000137497homo_sapiensENSP0000037729894.231788.9362delphinapterus_leucasENSDLEP0000000005593.788288.5176
ENSG00000137497homo_sapiensENSP0000037729882.931477.5887physeter_catodonENSPCTP0000502808887.00481.3988
ENSG00000137497homo_sapiensENSP0000037729889.40981.7021mus_caroliMGP_CAROLIEiJ_P008106590.39282.6004
ENSG00000137497homo_sapiensENSP0000037729889.598181.9385mus_musculusENSMUSP0000008191290.496782.7603
ENSG00000137497homo_sapiensENSP0000037729890.685684.7281dipodomys_ordiiENSDORP0000001121991.073185.0902
ENSG00000137497homo_sapiensENSP0000037729878.439773.3806mustela_putorius_furoENSMPUP0000001025092.578186.6071
ENSG00000137497homo_sapiensENSP0000037729897.494195.0827aotus_nancymaaeENSANAP0000004249397.218394.8138
ENSG00000137497homo_sapiensENSP0000037729897.825195.461saimiri_boliviensis_boliviensisENSSBOP0000003278497.825195.461
ENSG00000137497homo_sapiensENSP0000037729898.628896.974chlorocebus_sabaeusENSCSAP0000000055698.489196.8366
ENSG00000137497homo_sapiensENSP0000037729859.952756.0756tupaia_belangeriENSTBEP0000001434260.640856.7193
ENSG00000137497homo_sapiensENSP0000037729889.456382.695mesocricetus_auratusENSMAUP0000000737789.456382.695
ENSG00000137497homo_sapiensENSP0000037729894.27989.1726phocoena_sinusENSPSNP0000000902693.835388.7529
ENSG00000137497homo_sapiensENSP0000037729894.326289.7872camelus_dromedariusENSCDRP0000500066393.882489.3647
ENSG00000137497homo_sapiensENSP0000037729893.427989.2671carlito_syrichtaENSTSYP0000001257294.908790.682
ENSG00000137497homo_sapiensENSP0000037729844.53943.4988panthera_tigris_altaicaENSPTIP0000002675496.122593.8775
ENSG00000137497homo_sapiensENSP0000037729889.503581.6548rattus_norvegicusENSRNOP0000000047489.88682.0038
ENSG00000137497homo_sapiensENSP0000037729894.657291.2057prolemur_simusENSPSMP0000001872994.836691.3785
ENSG00000137497homo_sapiensENSP0000037729886.288479.1962microtus_ochrogasterENSMOCP0000002089288.894381.5879
ENSG00000137497homo_sapiensENSP0000037729861.796756.4066sorex_araneusENSSARP0000000635372.97666.6108
ENSG00000137497homo_sapiensENSP0000037729889.503582.7423peromyscus_maniculatus_bairdiiENSPEMP0000001422190.401183.5721
ENSG00000137497homo_sapiensENSP0000037729892.43586.2411bos_mutusENSBMUP0000003546792.478786.2819
ENSG00000137497homo_sapiensENSP0000037729889.645481.8913mus_spicilegusENSMSIP0000003417990.544482.7125
ENSG00000137497homo_sapiensENSP0000037729889.7483.357cricetulus_griseus_chok1gshdENSCGRP0000102420789.952683.5545
ENSG00000137497homo_sapiensENSP0000037729892.056787.4705pteropus_vampyrusENSPVAP0000001489792.187587.5947
ENSG00000137497homo_sapiensENSP0000037729893.853488.6998myotis_lucifugusENSMLUP0000001283293.367888.2408
ENSG00000137497homo_sapiensENSP0000037729878.959866.6667vombatus_ursinusENSVURP0001002910980.327167.8211
ENSG00000137497homo_sapiensENSP0000037729894.420889.409rhinolophus_ferrumequinumENSRFEP0001001572993.976588.9882
ENSG00000137497homo_sapiensENSP0000037729881.702176.8794neovison_visonENSNVIP0000002623992.554987.0916
ENSG00000137497homo_sapiensENSP0000037729889.976483.7825bos_taurusENSBTAP0000002455390.835384.5823
ENSG00000137497homo_sapiensENSP0000037729891.820386.1939heterocephalus_glaber_femaleENSHGLP0000001974390.747785.1869
ENSG00000137497homo_sapiensENSP0000037729821.371220heterocephalus_glaber_femaleENSHGLP0000003678689.682583.9286
ENSG00000137497homo_sapiensENSP0000037729898.628897.0213rhinopithecus_bietiENSRBIP0000002080598.489196.8839
ENSG00000137497homo_sapiensENSP0000037729893.900788.747canis_lupus_dingoENSCAFP0002000601694.346889.1686
ENSG00000137497homo_sapiensENSP0000037729893.711688.6052sciurus_vulgarisENSSVLP0000501759493.139188.0639
ENSG00000137497homo_sapiensENSP0000037729876.879463.8298phascolarctos_cinereusENSPCIP0000004386179.394565.918
ENSG00000137497homo_sapiensENSP0000037729867.23463.1206procavia_capensisENSPCAP0000000212467.425363.3001
ENSG00000137497homo_sapiensENSP0000037729891.205785.2955nannospalax_galiliENSNGAP0000001862292.032486.0687
ENSG00000137497homo_sapiensENSP0000037729892.482386.3357bos_grunniensENSBGRP0000001492892.569886.4174
ENSG00000137497homo_sapiensENSP0000037729891.536685.3428chinchilla_lanigeraENSCLAP0000002435591.666785.464
ENSG00000137497homo_sapiensENSP0000037729892.718786.8085cervus_hanglu_yarkandensisENSCHYP0000000114192.369386.4814
ENSG00000137497homo_sapiensENSP0000037729891.678585.2955catagonus_wagneriENSCWAP0000000005292.157885.7414
ENSG00000137497homo_sapiensENSP0000037729893.096988.2742ictidomys_tridecemlineatusENSSTOP0000002925393.494888.6515
ENSG00000137497homo_sapiensENSP0000037729894.27990.3073otolemur_garnettiiENSOGAP0000000085994.10190.1369
ENSG00000137497homo_sapiensENSP0000037729896.784994.1844cebus_imitatorENSCCAP0000003803197.290994.6768
ENSG00000137497homo_sapiensENSP0000037729893.711688.7943urocitellus_parryiiENSUPAP0001002468893.270688.3765
ENSG00000137497homo_sapiensENSP0000037729892.718786.8558moschus_moschiferusENSMMSP0000001928590.410384.6934
ENSG00000137497homo_sapiensENSP0000037729898.439796.7849rhinopithecus_roxellanaENSRROP0000001470795.068593.4703
ENSG00000137497homo_sapiensENSP0000037729889.692781.9385mus_pahariMGP_PahariEiJ_P001790190.722182.879
ENSG00000137497homo_sapiensENSP0000037729893.94890.6383propithecus_coquereliENSPCOP0000003212695.482992.1192
ENSG00000137497homo_sapiensENSP0000037729818.20337.42317drosophila_melanogasterFBpp011213633.920713.8326
ENSG00000137497homo_sapiensENSP0000037729853.806134.7045callorhinchus_miliiENSCMIP0000001600554.164734.9357
ENSG00000137497homo_sapiensENSP0000037729863.120641.6076latimeria_chalumnaeENSLACP0000001278461.94940.8353
ENSG00000137497homo_sapiensENSP0000037729854.893633.9953lepisosteus_oculatusENSLOCP0000000956750.434431.2337
ENSG00000137497homo_sapiensENSP0000037729847.659627.8014danio_rerioENSDARP0000013270841.142924
ENSG00000137497homo_sapiensENSP0000037729846.241127.1395carassius_auratusENSCARP0000012353535.370720.7595
ENSG00000137497homo_sapiensENSP0000037729842.269524.1135carassius_auratusENSCARP0000003297644.213625.2226
ENSG00000137497homo_sapiensENSP0000037729848.652528.3688carassius_auratusENSCARP0000012454537.04121.5983
ENSG00000137497homo_sapiensENSP0000037729848.132427.896ictalurus_punctatusENSIPUP0000000329241.231323.8963
ENSG00000137497homo_sapiensENSP0000037729846.430326.8085esox_luciusENSELUP0000001078241.680824.0662
ENSG00000137497homo_sapiensENSP0000037729863.546142.0331xenopus_tropicalisENSXETP0000007068758.333338.5851
ENSG00000137497homo_sapiensENSP0000037729873.806156.2175chrysemys_picta_belliiENSCPBP0000000500269.532352.9621
ENSG00000137497homo_sapiensENSP0000037729869.881853.2388sphenodon_punctatusENSSPUP0000002356869.033252.5922
ENSG00000137497homo_sapiensENSP0000037729870.165554.6572crocodylus_porosusENSCPRP0000502416869.248753.9431
ENSG00000137497homo_sapiensENSP0000037729865.295547.0922laticauda_laticaudataENSLLTP0000001154563.523545.8142
ENSG00000137497homo_sapiensENSP0000037729851.583937.2104pseudonaja_textilisENSPTXP0000002365364.556246.568
ENSG00000137497homo_sapiensENSP000003772989.12537.42317anas_platyrhynchos_platyrhynchosENSAPLP0000002438070.43857.2993
ENSG00000137497homo_sapiensENSP0000037729856.97442.8842anas_platyrhynchos_platyrhynchosENSAPLP0000002235967.130950.5292
ENSG00000137497homo_sapiensENSP0000037729869.881854.5154gallus_gallusENSGALP0001000344362.760148.9597
ENSG00000137497homo_sapiensENSP0000037729869.929154.8463meleagris_gallopavoENSMGAP0000002801165.096851.0563
ENSG00000137497homo_sapiensENSP0000037729854.089840.5201serinus_canariaENSSCAP0000002322168.135851.0423
ENSG00000137497homo_sapiensENSP0000037729855.366441.182parus_majorENSPMJP0000001585467.923450.522
ENSG00000137497homo_sapiensENSP0000037729857.257741.6076anolis_carolinensisENSACAP0000002019665.072547.2864
ENSG00000137497homo_sapiensENSP0000037729833.664325.2482naja_najaENSNNAP0000001739160.906845.6801
ENSG00000137497homo_sapiensENSP0000037729861.040243.5934podarcis_muralisENSPMRP0000000121566.137347.2336
ENSG00000137497homo_sapiensENSP0000037729850.070937.2577geospiza_fortisENSGFOP0000002093864.612648.0781
ENSG00000137497homo_sapiensENSP0000037729854.468140.7565taeniopygia_guttataENSTGUP0000002711769.106251.7097
ENSG00000137497homo_sapiensENSP0000037729841.51322.2695kryptolebias_marmoratusENSKMAP0000001013244.773124.0184
ENSG00000137497homo_sapiensENSP0000037729866.05248.8889salvator_merianaeENSSMRP0000000181965.989648.8427
ENSG00000137497homo_sapiensENSP0000037729844.397231.3475pelodiscus_sinensisENSPSIP0000000241065.027745.9141
ENSG00000137497homo_sapiensENSP0000037729873.995355.9811gopherus_evgoodeiENSGEVP0000500213770.400453.2614
ENSG00000137497homo_sapiensENSP0000037729873.711655.8865chelonoidis_abingdoniiENSCABP0000002498870.098953.1475
ENSG00000137497homo_sapiensENSP0000037729840.803822.0804seriola_dumeriliENSSDUP0000000078243.193223.3734
ENSG00000137497homo_sapiensENSP0000037729861.607646.2884struthio_camelus_australisENSSCUP0000001099368.291451.3103
ENSG00000137497homo_sapiensENSP0000037729870.92255.3191anser_brachyrhynchusENSABRP0000000138267.174252.3959
ENSG00000137497homo_sapiensENSP0000037729843.687923.2151myripristis_murdjanENSMMDP0000504539343.646723.1932
ENSG00000137497homo_sapiensENSP0000037729860.425546.3357strigops_habroptilaENSSHBP0000502101466.87651.2821
ENSG00000137497homo_sapiensENSP0000037729873.995356.3121terrapene_carolina_triunguisENSTMTP0000000623270.368753.5522
ENSG00000137497homo_sapiensENSP0000037729847.659628.1797hucho_huchoENSHHUP0000007134443.712125.8456
ENSG00000137497homo_sapiensENSP0000037729846.288424.9645betta_splendensENSBSLP0000002250338.849220.9524
ENSG00000137497homo_sapiensENSP0000037729845.815624.2553anabas_testudineusENSATEP0000000949742.020822.2463
ENSG00000137497homo_sapiensENSP0000037729824.018910.2128ciona_savignyiENSCSAVP0000001711330.382812.9187
ENSG00000137497homo_sapiensENSP0000037729868.321552.8605aquila_chrysaetos_chrysaetosENSACCP0002001487668.25752.8106
ENSG00000137497homo_sapiensENSP0000037729851.631238.8652ficedula_albicollisENSFALP0000000657567.826151.0559
ENSG00000137497homo_sapiensENSP0000037729848.416128.3215cyprinus_carpio_carpioENSCCRP0000016627735.929821.0175
ENSG00000137497homo_sapiensENSP0000037729848.274228.0851cyprinus_carpio_carpioENSCCRP0000012470241.758724.2945
ENSG00000137497homo_sapiensENSP0000037729853.995339.2435coturnix_japonicaENSCJPP0000500558957.735141.9616
ENSG00000137497homo_sapiensENSP0000037729833.002419.2435sinocyclocheilus_grahamiENSSGRP0000006052040.416923.5669
ENSG00000137497homo_sapiensENSP0000037729844.349927.7541scleropages_formosusENSSFOP0001502548450.348931.5083
ENSG00000137497homo_sapiensENSP0000037729864.349942.6005leptobrachium_leishanenseENSLLEP0000004000459.510339.3966

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000132involved_in establishment of mitotic spindle orientation4IBA,IDA,IMP,ISSHomo_sapiens(9606)Process
GO:0000922is_active_in spindle pole2IBA,IDAHomo_sapiens(9606)Component
GO:0001578involved_in microtubule bundle formation1IMPHomo_sapiens(9606)Process
GO:0005198enables structural molecule activity1TASHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus1IDAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005694located_in chromosome1IEAHomo_sapiens(9606)Component
GO:0005813is_active_in centrosome2IBA,IDAHomo_sapiens(9606)Component
GO:0005819located_in spindle1TASHomo_sapiens(9606)Component
GO:0005829located_in cytosol2IDA,TASHomo_sapiens(9606)Component
GO:0005876is_active_in spindle microtubule2IBA,IDAHomo_sapiens(9606)Component
GO:0005886located_in plasma membrane1IDAHomo_sapiens(9606)Component
GO:0005938located_in cell cortex1IDAHomo_sapiens(9606)Component
GO:0006997involved_in nucleus organization1TASHomo_sapiens(9606)Process
GO:0008017enables microtubule binding2IBA,IDAHomo_sapiens(9606)Function
GO:0015631enables tubulin binding1IDAHomo_sapiens(9606)Function
GO:0016328located_in lateral plasma membrane1IEAHomo_sapiens(9606)Component
GO:0016363located_in nuclear matrix1IDAHomo_sapiens(9606)Component
GO:0019904enables protein domain specific binding1IPIHomo_sapiens(9606)Function
GO:0030425located_in dendrite1IEAHomo_sapiens(9606)Component
GO:0030513involved_in positive regulation of BMP signaling pathway1ISSHomo_sapiens(9606)Process
GO:0030953involved_in astral microtubule organization2IDA,IMPHomo_sapiens(9606)Process
GO:0031116involved_in positive regulation of microtubule polymerization1IMPHomo_sapiens(9606)Process
GO:0031616located_in spindle pole centrosome1IDAHomo_sapiens(9606)Component
GO:0032388involved_in positive regulation of intracellular transport1IMPHomo_sapiens(9606)Process
GO:0032991part_of protein-containing complex2IDA,IMPHomo_sapiens(9606)Component
GO:0035091enables phosphatidylinositol binding1IDAHomo_sapiens(9606)Function
GO:0035371located_in microtubule plus-end1IDAHomo_sapiens(9606)Component
GO:0036449located_in microtubule minus-end1IDAHomo_sapiens(9606)Component
GO:0043025located_in neuronal cell body1IEAHomo_sapiens(9606)Component
GO:0044877enables protein-containing complex binding1IDAHomo_sapiens(9606)Function
GO:0045618involved_in positive regulation of keratinocyte differentiation1ISSHomo_sapiens(9606)Process
GO:0051010enables microtubule plus-end binding1IDAHomo_sapiens(9606)Function
GO:0051011enables microtubule minus-end binding1IDAHomo_sapiens(9606)Function
GO:0051301involved_in cell division1IEAHomo_sapiens(9606)Process
GO:0051321involved_in meiotic cell cycle1IEAHomo_sapiens(9606)Process
GO:0051798involved_in positive regulation of hair follicle development1ISSHomo_sapiens(9606)Process
GO:0051984involved_in positive regulation of chromosome segregation1IMPHomo_sapiens(9606)Process
GO:0055028located_in cortical microtubule1IDAHomo_sapiens(9606)Component
GO:0055048involved_in anastral spindle assembly1IMPHomo_sapiens(9606)Process
GO:0060236involved_in regulation of mitotic spindle organization2IDA,IMPHomo_sapiens(9606)Process
GO:0061673located_in mitotic spindle astral microtubule1IDAHomo_sapiens(9606)Component
GO:0070062located_in extracellular exosome1HDAHomo_sapiens(9606)Component
GO:0070840enables dynein complex binding1IDAHomo_sapiens(9606)Function
GO:0072686located_in mitotic spindle1IDAHomo_sapiens(9606)Component
GO:0090235involved_in regulation of metaphase plate congression1IMPHomo_sapiens(9606)Process
GO:0097427located_in microtubule bundle1IDAHomo_sapiens(9606)Component
GO:0097431located_in mitotic spindle pole2IDA,IMPHomo_sapiens(9606)Component
GO:0097575located_in lateral cell cortex1ISSHomo_sapiens(9606)Component
GO:0097718enables disordered domain specific binding1IMPHomo_sapiens(9606)Function
GO:0099738located_in cell cortex region1IDAHomo_sapiens(9606)Component
GO:1902365involved_in positive regulation of protein localization to spindle pole body1IDAHomo_sapiens(9606)Process
GO:1902846involved_in positive regulation of mitotic spindle elongation1IMPHomo_sapiens(9606)Process
GO:1904778involved_in positive regulation of protein localization to cell cortex1IMPHomo_sapiens(9606)Process
GO:1905720located_in cytoplasmic microtubule bundle1IDAHomo_sapiens(9606)Component
GO:1905820involved_in positive regulation of chromosome separation1IMPHomo_sapiens(9606)Process
GO:1905832involved_in positive regulation of spindle assembly1IMPHomo_sapiens(9606)Process
GO:1990023located_in mitotic spindle midzone1IDAHomo_sapiens(9606)Component

Expression