RBP Type	Non-canonical_RBPs
Diseases	Disease
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	N.A.
Localizations	Nucleoli
BulkPerturb-seq

Ensembl ID	ENSG00000137168	Gene ID	51645	Accession	9260
Symbol	PPIL1	Alias	CYPL1;PCH14;hCyPX;PPIase;CGI-124	Full Name	peptidylprolyl isomerase like 1
Status	Confidence	Length	19975 bases	Strand	Minus strand
Position	6 : 36854829 - 36874803	RNA binding domain	N.A.
Summary	This gene is a member of the cyclophilin family of peptidylprolyl isomerases (PPIases). The cyclophilins are a highly conserved, ubiquitous family, members of which play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. Based on similarity to other PPIases, this protein could accelerate the folding of proteins and might catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. [provided by RefSeq, Jul 2008]

Protein	Domain	Pfam ID	E-value	Domain number

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal
33220177	Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly.	Guoliang Chai	2021-01-20	Neuron

Name	Transcript ID	bp	Protein	Translation ID

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000398	involved_in mRNA splicing, via spliceosome	3	IC,IDA,IMP	Homo_sapiens(9606)	Process
GO:0000413	involved_in protein peptidyl-prolyl isomerization	2	IBA,IDA	Homo_sapiens(9606)	Process
GO:0003755	enables peptidyl-prolyl cis-trans isomerase activity	2	IBA,IDA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	located_in nucleus	1	IDA	Homo_sapiens(9606)	Component
GO:0005654	located_in nucleoplasm	1	TAS	Homo_sapiens(9606)	Component
GO:0006457	involved_in protein folding	1	IEA	Homo_sapiens(9606)	Process
GO:0016018	enables cyclosporin A binding	1	IDA	Homo_sapiens(9606)	Function
GO:0071007	part_of U2-type catalytic step 2 spliceosome	1	IDA	Homo_sapiens(9606)	Component
GO:0071013	part_of catalytic step 2 spliceosome	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0097718	enables disordered domain specific binding	1	IPI	Homo_sapiens(9606)	Function
GO:1990403	involved_in embryonic brain development	1	IMP	Homo_sapiens(9606)	Process