RBPWorld - a comprehensive database of RNA Binding Proteins

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RBP World!

Functions and Diseases

RBP Type	Canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	N.A.
Localizations	N.A.
BulkPerturb-seq

Description

Ensembl ID	ENSG00000137133	Gene ID	84681	Accession	18344
Symbol	HINT2	Alias	HIT-17	Full Name	histidine triad nucleotide binding protein 2
Status	Confidence	Length	2083 bases	Strand	Minus strand
Position	9 : 35812960 - 35815042	RNA binding domain	DcpS_C
Summary	Histidine triad proteins, such as HINT2, are nucleotide hydrolases and transferases that act on the alpha-phosphate of ribonucleotides (Brenner, 2002 [PubMed 12119013]).[supplied by OMIM, Mar 2008]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000259667	DcpS_C	PF11969	1.4e-19	1

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
HINT2-207	ENST00000490578	717	No protein	-
HINT2-204	ENST00000472085	569	No protein	-
HINT2-201	ENST00000259667	649	163aa	ENSP00000259667
HINT2-206	ENST00000474908	2167	No protein	-
HINT2-205	ENST00000474848	853	No protein	-
HINT2-203	ENST00000471774	443	No protein	-
HINT2-202	ENST00000461169	734	No protein	-

Gene Model

Click here to download ENSG00000137133's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000137133's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000166	enables nucleotide binding	1	IEA	Homo_sapiens(9606)	Function
GO:0005737	is_active_in cytoplasm	1	IBA	Homo_sapiens(9606)	Component
GO:0005739	is_active_in mitochondrion	3	IBA,IDA,ISS	Homo_sapiens(9606)	Component
GO:0005741	located_in mitochondrial outer membrane	1	TAS	Homo_sapiens(9606)	Component
GO:0006694	involved_in steroid biosynthetic process	1	IEA	Homo_sapiens(9606)	Process
GO:0006915	involved_in apoptotic process	1	IEA	Homo_sapiens(9606)	Process
GO:0016042	involved_in lipid catabolic process	1	IEA	Homo_sapiens(9606)	Process
GO:0016787	enables hydrolase activity	1	IBA	Homo_sapiens(9606)	Function
GO:0043530	enables adenosine 5-monophosphoramidase activity	1	IDA	Homo_sapiens(9606)	Function
GO:2000757	involved_in negative regulation of peptidyl-lysine acetylation	1	IEA	Homo_sapiens(9606)	Process

Expression