RBP Type	Non-canonical_RBPs
Diseases	N.A.
Drug	Drug
Main interacting RNAs	N.A.
Moonlighting functions	Metabolic enzyme
Localizations	N.A.
BulkPerturb-seq

Ensembl ID	ENSG00000136930	Gene ID	5695	Accession	9544
Symbol	PSMB7	Alias	NA	Full Name	proteasome 20S subunit beta 7
Status	Confidence	Length	61980 bases	Strand	Minus strand
Position	9 : 124353465 - 124415444	RNA binding domain	N.A.
Summary	The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. The encoded protein is a member of the proteasome B-type family, also known as the T1B family, and is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon, and proteolytic processing is required to generate a mature subunit. A pseudogene of this gene is located on the long arm of chromosome 14. [provided by RefSeq, Jul 2012]

Protein	Domain	Pfam ID	E-value	Domain number

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
PSMB7-201	ENST00000259457	984	277aa	ENSP00000259457
PSMB7-206	ENST00000498485	967	No protein	-
PSMB7-204	ENST00000474081	546	No protein	-
PSMB7-205	ENST00000478817	388	No protein	-
PSMB7-202	ENST00000441097	650	210aa	ENSP00000393157
PSMB7-203	ENST00000466951	462	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000502	part_of proteasome complex	2	IDA,NAS	Homo_sapiens(9606)	Component
GO:0004175	enables endopeptidase activity	1	IBA	Homo_sapiens(9606)	Function
GO:0004298	enables threonine-type endopeptidase activity	1	IEA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005576	located_in extracellular region	1	TAS	Homo_sapiens(9606)	Component
GO:0005634	located_in nucleus	3	HDA,IBA,IDA	Homo_sapiens(9606)	Component
GO:0005654	located_in nucleoplasm	2	IDA,TAS	Homo_sapiens(9606)	Component
GO:0005737	is_active_in cytoplasm	1	IDA	Homo_sapiens(9606)	Component
GO:0005829	located_in cytosol	2	IDA,TAS	Homo_sapiens(9606)	Component
GO:0005839	part_of proteasome core complex	2	IDA,ISS	Homo_sapiens(9606)	Component
GO:0010498	involved_in proteasomal protein catabolic process	1	IBA	Homo_sapiens(9606)	Process
GO:0016604	located_in nuclear body	1	IDA	Homo_sapiens(9606)	Component
GO:0019774	part_of proteasome core complex, beta-subunit complex	2	IBA,ISS	Homo_sapiens(9606)	Component
GO:0034774	located_in secretory granule lumen	1	TAS	Homo_sapiens(9606)	Component
GO:0043161	involved_in proteasome-mediated ubiquitin-dependent protein catabolic process	1	NAS	Homo_sapiens(9606)	Process
GO:1904813	located_in ficolin-1-rich granule lumen	1	TAS	Homo_sapiens(9606)	Component