Functions and Diseases

RBP Type Canonical_RBPs
Diseases N.A.
Drug N.A.
Main interacting RNAs rRNA
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000136897 Gene ID 54534 Accession 16654
Symbol MRPL50 Alias mL50;MRP-L50 Full Name mitochondrial ribosomal protein L50
Status Confidence Length 10986 bases Strand Minus strand
Position 9 : 101387633 - 101398618 RNA binding domain Ribosomal_L50
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a putative 39S subunit protein and belongs to the L47P ribosomal protein family. Pseudogenes corresponding to this gene are found on chromosomes 2p, 2q, 5p, and 10q. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000363999 Ribosomal_L50 PF10501 1.2e-10 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
MRPL50-201 ENST00000374865 3336 158aa ENSP00000363999

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000136897

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000136897homo_sapiensENSP0000036399998.101396.2025nomascus_leucogenysENSNLEP0000002077798.101396.2025
ENSG00000136897homo_sapiensENSP0000036399998.101397.4684pan_paniscusENSPPAP0000000880598.101397.4684
ENSG00000136897homo_sapiensENSP0000036399998.101398.1013pongo_abeliiENSPPYP0000002179598.101398.1013
ENSG00000136897homo_sapiensENSP0000036399998.734298.1013pan_troglodytesENSPTRP0000008214698.734298.1013
ENSG00000136897homo_sapiensENSP0000036399999.367197.4684gorilla_gorillaENSGGOP0000002770398.12596.25
ENSG00000136897homo_sapiensENSP0000036399973.417758.2278ornithorhynchus_anatinusENSOANP0000000754547.154537.3984
ENSG00000136897homo_sapiensENSP0000036399970.253255.6962sarcophilus_harrisiiENSSHAP0000001419169.37555
ENSG00000136897homo_sapiensENSP0000036399963.291148.1013notamacropus_eugeniiENSMEUP0000000515777.519458.9147
ENSG00000136897homo_sapiensENSP0000036399951.898747.4684choloepus_hoffmanniENSCHOP0000000942687.23479.7872
ENSG00000136897homo_sapiensENSP0000036399984.177276.5823dasypus_novemcinctusENSDNOP0000002782782.098874.6914
ENSG00000136897homo_sapiensENSP0000036399979.113969.6203erinaceus_europaeusENSEEUP0000001358685.03474.8299
ENSG00000136897homo_sapiensENSP0000036399981.012770.8861echinops_telfairiENSETEP0000000128079.503169.5652
ENSG00000136897homo_sapiensENSP0000036399991.772187.3418callithrix_jacchusENSCJAP0000008373091.19586.7924
ENSG00000136897homo_sapiensENSP0000036399998.101396.2025cercocebus_atysENSCATP0000003286598.101396.2025
ENSG00000136897homo_sapiensENSP0000036399997.468495.5696macaca_fascicularisENSMFAP0000005969497.468495.5696
ENSG00000136897homo_sapiensENSP0000036399998.101396.2025macaca_mulattaENSMMUP0000007348898.101396.2025
ENSG00000136897homo_sapiensENSP0000036399998.101396.2025macaca_nemestrinaENSMNEP0000003337298.101396.2025
ENSG00000136897homo_sapiensENSP0000036399998.101396.2025papio_anubisENSPANP0000005806798.101396.2025
ENSG00000136897homo_sapiensENSP0000036399998.101396.2025mandrillus_leucophaeusENSMLEP0000002654598.101396.2025
ENSG00000136897homo_sapiensENSP0000036399972.784868.9873tursiops_truncatusENSTTRP0000001359789.843885.1562
ENSG00000136897homo_sapiensENSP0000036399986.07677.2152vulpes_vulpesENSVVUP0000002621685.534676.7296
ENSG00000136897homo_sapiensENSP0000036399984.177275.9494mus_spretusMGP_SPRETEiJ_P006481583.647875.4717
ENSG00000136897homo_sapiensENSP0000036399987.341882.9114equus_asinusENSEASP0000505116687.341882.9114
ENSG00000136897homo_sapiensENSP0000036399986.07676.5823capra_hircusENSCHIP0000001416585.534676.1006
ENSG00000136897homo_sapiensENSP0000036399984.810177.8481loxodonta_africanaENSLAFP0000002538784.276777.3585
ENSG00000136897homo_sapiensENSP0000036399986.708978.481panthera_leoENSPLOP0000001027586.163577.9874
ENSG00000136897homo_sapiensENSP0000036399985.44376.5823bos_indicus_hybridENSBIXP0000503348984.905776.1006
ENSG00000136897homo_sapiensENSP0000036399981.645672.7848oryctolagus_cuniculusENSOCUP0000000548181.132172.327
ENSG00000136897homo_sapiensENSP0000036399987.974783.5443equus_caballusENSECAP0000005613187.974783.5443
ENSG00000136897homo_sapiensENSP0000036399985.44377.8481canis_lupus_familiarisENSCAFP0084501251784.905777.3585
ENSG00000136897homo_sapiensENSP0000036399986.708978.481panthera_pardusENSPPRP0000000676986.163577.9874
ENSG00000136897homo_sapiensENSP0000036399987.341881.0127marmota_marmota_marmotaENSMMMP0000000458686.792480.5031
ENSG00000136897homo_sapiensENSP0000036399987.974783.5443balaenoptera_musculusENSBMSP0001001003687.421483.0189
ENSG00000136897homo_sapiensENSP0000036399982.911476.5823cavia_porcellusENSCPOP0000002595782.911476.5823
ENSG00000136897homo_sapiensENSP0000036399984.810179.7468ursus_americanusENSUAMP0000002710984.276779.2453
ENSG00000136897homo_sapiensENSP0000036399972.151958.2278monodelphis_domesticaENSMODP0000002779871.2557.5
ENSG00000136897homo_sapiensENSP0000036399986.07676.5823bison_bison_bisonENSBBBP0000000584485.534676.1006
ENSG00000136897homo_sapiensENSP0000036399986.07680.3797monodon_monocerosENSMMNP0001501993485.534679.8742
ENSG00000136897homo_sapiensENSP0000036399985.44379.7468sus_scrofaENSSSCP0000002068868.181863.6364
ENSG00000136897homo_sapiensENSP0000036399991.139287.3418microcebus_murinusENSMICP0000004665290.56686.7924
ENSG00000136897homo_sapiensENSP0000036399988.607684.8101microcebus_murinusENSMICP0000004625188.050384.2767
ENSG00000136897homo_sapiensENSP0000036399989.873486.7089microcebus_murinusENSMICP0000005092689.308286.1635
ENSG00000136897homo_sapiensENSP0000036399984.177274.0506octodon_degusENSODEP0000000707084.177274.0506
ENSG00000136897homo_sapiensENSP0000036399982.278572.7848jaculus_jaculusENSJJAP0000001234181.76172.327
ENSG00000136897homo_sapiensENSP0000036399985.44375.9494ovis_aries_rambouilletENSOARP0002000377784.905775.4717
ENSG00000136897homo_sapiensENSP0000036399984.810179.7468ursus_maritimusENSUMAP0000001766984.276779.2453
ENSG00000136897homo_sapiensENSP0000036399982.278573.4177ochotona_princepsENSOPRP0000001420181.2572.5
ENSG00000136897homo_sapiensENSP0000036399986.07680.3797delphinapterus_leucasENSDLEP0000001602485.534679.8742
ENSG00000136897homo_sapiensENSP0000036399987.974782.2785physeter_catodonENSPCTP0000501295287.421481.761
ENSG00000136897homo_sapiensENSP0000036399985.44377.8481mus_caroliMGP_CAROLIEiJ_P006234884.905777.3585
ENSG00000136897homo_sapiensENSP0000036399985.44377.2152mus_musculusENSMUSP0000006247684.905776.7296
ENSG00000136897homo_sapiensENSP0000036399981.012772.7848dipodomys_ordiiENSDORP0000001206580.503172.327
ENSG00000136897homo_sapiensENSP0000036399983.544379.7468mustela_putorius_furoENSMPUP0000000684483.018979.2453
ENSG00000136897homo_sapiensENSP0000036399975.316571.519aotus_nancymaaeENSANAP0000000014391.538586.9231
ENSG00000136897homo_sapiensENSP0000036399991.772187.9747aotus_nancymaaeENSANAP0000000205991.19587.4214
ENSG00000136897homo_sapiensENSP0000036399993.03888.6076aotus_nancymaaeENSANAP0000000008592.452888.0503
ENSG00000136897homo_sapiensENSP0000036399993.03887.9747saimiri_boliviensis_boliviensisENSSBOP0000001035492.452887.4214
ENSG00000136897homo_sapiensENSP0000036399986.07679.1139vicugna_pacosENSVPAP0000000207485.534678.6164
ENSG00000136897homo_sapiensENSP0000036399998.101396.2025chlorocebus_sabaeusENSCSAP0000000740198.101396.2025
ENSG00000136897homo_sapiensENSP0000036399973.417766.4557tupaia_belangeriENSTBEP0000000840891.338682.6772
ENSG00000136897homo_sapiensENSP0000036399973.417766.4557tupaia_belangeriENSTBEP0000000389791.338682.6772
ENSG00000136897homo_sapiensENSP0000036399981.645672.7848mesocricetus_auratusENSMAUP0000000292681.132172.327
ENSG00000136897homo_sapiensENSP0000036399978.48171.519phocoena_sinusENSPSNP0000002177081.045873.8562
ENSG00000136897homo_sapiensENSP0000036399986.07678.481camelus_dromedariusENSCDRP0000502059585.534677.9874
ENSG00000136897homo_sapiensENSP0000036399989.873482.2785carlito_syrichtaENSTSYP0000002415289.308281.761
ENSG00000136897homo_sapiensENSP0000036399986.708979.1139panthera_tigris_altaicaENSPTIP0000001480086.163578.6164
ENSG00000136897homo_sapiensENSP0000036399981.012770.2532rattus_norvegicusENSRNOP0000009137965.979457.2165
ENSG00000136897homo_sapiensENSP0000036399988.607685.443prolemur_simusENSPSMP0000002247188.607685.443
ENSG00000136897homo_sapiensENSP0000036399979.113972.7848microtus_ochrogasterENSMOCP0000001870478.12571.875
ENSG00000136897homo_sapiensENSP0000036399981.012773.4177sorex_araneusENSSARP0000001184080.503172.956
ENSG00000136897homo_sapiensENSP0000036399982.911475.9494peromyscus_maniculatus_bairdiiENSPEMP0000003602381.87575
ENSG00000136897homo_sapiensENSP0000036399984.810175.9494bos_mutusENSBMUP0000000289484.276775.4717
ENSG00000136897homo_sapiensENSP0000036399984.810177.2152mus_spicilegusENSMSIP0000003187284.276776.7296
ENSG00000136897homo_sapiensENSP0000036399982.911475.3165cricetulus_griseus_chok1gshdENSCGRP0000102674482.389974.8428
ENSG00000136897homo_sapiensENSP0000036399980.379774.0506pteropus_vampyrusENSPVAP0000000088483.552676.9737
ENSG00000136897homo_sapiensENSP0000036399984.177271.519myotis_lucifugusENSMLUP0000000548983.647871.0692
ENSG00000136897homo_sapiensENSP0000036399970.253255.6962vombatus_ursinusENSVURP0001000380269.37555
ENSG00000136897homo_sapiensENSP0000036399984.177280.3797neovison_visonENSNVIP0000001849383.647879.8742
ENSG00000136897homo_sapiensENSP0000036399985.44376.5823bos_taurusENSBTAP0000001179884.905776.1006
ENSG00000136897homo_sapiensENSP0000036399984.177277.2152heterocephalus_glaber_femaleENSHGLP0000000613784.177277.2152
ENSG00000136897homo_sapiensENSP0000036399996.202594.9367rhinopithecus_bietiENSRBIP0000002704696.202594.9367
ENSG00000136897homo_sapiensENSP0000036399986.07678.481canis_lupus_dingoENSCAFP0002002475985.534677.9874
ENSG00000136897homo_sapiensENSP0000036399984.177278.481sciurus_vulgarisENSSVLP0000501219983.647877.9874
ENSG00000136897homo_sapiensENSP0000036399985.44379.1139sciurus_vulgarisENSSVLP0000502805984.905778.6164
ENSG00000136897homo_sapiensENSP0000036399970.253252.5316phascolarctos_cinereusENSPCIP0000005489772.54954.2484
ENSG00000136897homo_sapiensENSP0000036399970.886160.7595procavia_capensisENSPCAP0000000631287.575
ENSG00000136897homo_sapiensENSP0000036399984.177275.9494nannospalax_galiliENSNGAP0000002326283.647875.4717
ENSG00000136897homo_sapiensENSP0000036399968.987358.8608bos_grunniensENSBGRP0000000086662.285753.1429
ENSG00000136897homo_sapiensENSP0000036399984.810177.2152chinchilla_lanigeraENSCLAP0000001482384.810177.2152
ENSG00000136897homo_sapiensENSP0000036399986.07677.8481cervus_hanglu_yarkandensisENSCHYP0000001869986.07677.8481
ENSG00000136897homo_sapiensENSP0000036399984.177279.7468catagonus_wagneriENSCWAP0000001812684.177279.7468
ENSG00000136897homo_sapiensENSP0000036399986.708981.6456ictidomys_tridecemlineatusENSSTOP0000001659186.163581.1321
ENSG00000136897homo_sapiensENSP0000036399988.607684.1772otolemur_garnettiiENSOGAP0000001775988.050383.6478
ENSG00000136897homo_sapiensENSP0000036399991.772187.3418cebus_imitatorENSCCAP0000003101691.19586.7924
ENSG00000136897homo_sapiensENSP0000036399987.341882.2785urocitellus_parryiiENSUPAP0001001910586.792481.761
ENSG00000136897homo_sapiensENSP0000036399984.810176.5823moschus_moschiferusENSMMSP0000001968584.276776.1006
ENSG00000136897homo_sapiensENSP0000036399996.202594.9367rhinopithecus_roxellanaENSRROP0000002681996.202594.9367
ENSG00000136897homo_sapiensENSP0000036399996.202594.9367rhinopithecus_roxellanaENSRROP0000002516896.202594.9367
ENSG00000136897homo_sapiensENSP0000036399986.07677.8481mus_pahariMGP_PahariEiJ_P007748585.534677.3585
ENSG00000136897homo_sapiensENSP0000036399942.405120.8861caenorhabditis_elegansT21B10.1.123.508811.5789
ENSG00000136897homo_sapiensENSP0000036399941.139227.2152drosophila_melanogasterFBpp007660134.391522.7513
ENSG00000136897homo_sapiensENSP0000036399954.430436.076petromyzon_marinusENSPMAP0000001142451.49734.1317
ENSG00000136897homo_sapiensENSP0000036399960.126647.4684latimeria_chalumnaeENSLACP0000000404157.575845.4545
ENSG00000136897homo_sapiensENSP0000036399963.92453.7975chrysemys_picta_belliiENSCPBP0000001263163.92453.7975
ENSG00000136897homo_sapiensENSP0000036399968.354452.5316sphenodon_punctatusENSSPUP0000001083369.230853.2051
ENSG00000136897homo_sapiensENSP0000036399958.227843.038crocodylus_porosusENSCPRP0000502150759.354843.871
ENSG00000136897homo_sapiensENSP0000036399962.025345.5696laticauda_laticaudataENSLLTP0000001709649.746236.5482
ENSG00000136897homo_sapiensENSP0000036399960.126645.5696notechis_scutatusENSNSUP0000001376859.006244.7205
ENSG00000136897homo_sapiensENSP0000036399961.392448.1013pseudonaja_textilisENSPTXP0000002428960.248447.205
ENSG00000136897homo_sapiensENSP0000036399963.291150.6329anas_platyrhynchos_platyrhynchosENSAPLP0000000013762.550
ENSG00000136897homo_sapiensENSP0000036399962.658250.6329gallus_gallusENSGALP0001000793861.490749.6894
ENSG00000136897homo_sapiensENSP0000036399965.189952.5316meleagris_gallopavoENSMGAP0000001696363.190250.9202
ENSG00000136897homo_sapiensENSP0000036399958.227844.9367serinus_canariaENSSCAP0000000633167.153351.8248
ENSG00000136897homo_sapiensENSP0000036399965.822853.7975parus_majorENSPMJP0000001690654.736844.7368
ENSG00000136897homo_sapiensENSP0000036399962.025346.8354anolis_carolinensisENSACAP0000004004661.2546.25
ENSG00000136897homo_sapiensENSP0000036399959.493743.6709naja_najaENSNNAP0000000980957.668742.3313
ENSG00000136897homo_sapiensENSP0000036399964.55754.4304podarcis_muralisENSPMRP0000002597561.818252.1212
ENSG00000136897homo_sapiensENSP0000036399960.126646.2025geospiza_fortisENSGFOP0000000906957.228943.9759
ENSG00000136897homo_sapiensENSP0000036399961.392446.8354taeniopygia_guttataENSTGUP0000001835030.891723.5669
ENSG00000136897homo_sapiensENSP0000036399958.860844.3038taeniopygia_guttataENSTGUP0000003156556.707342.6829
ENSG00000136897homo_sapiensENSP0000036399965.822849.3671salvator_merianaeENSSMRP0000002682565.408849.0566
ENSG00000136897homo_sapiensENSP0000036399962.025351.8987pelodiscus_sinensisENSPSIP0000000030774.809262.5954
ENSG00000136897homo_sapiensENSP0000036399963.291153.7975gopherus_evgoodeiENSGEVP0000500515563.291153.7975
ENSG00000136897homo_sapiensENSP0000036399963.92453.7975chelonoidis_abingdoniiENSCABP0000002449163.92453.7975
ENSG00000136897homo_sapiensENSP0000036399962.658250struthio_camelus_australisENSSCUP0000001925572.262857.6642
ENSG00000136897homo_sapiensENSP0000036399965.822850.6329anser_brachyrhynchusENSABRP000000162866550
ENSG00000136897homo_sapiensENSP0000036399965.189949.3671strigops_habroptilaENSSHBP0000500294558.857144.5714
ENSG00000136897homo_sapiensENSP0000036399964.55750.6329terrapene_carolina_triunguisENSTMTP0000002237968.456453.6913
ENSG00000136897homo_sapiensENSP0000036399963.92453.7975terrapene_carolina_triunguisENSTMTP0000002939863.92453.7975
ENSG00000136897homo_sapiensENSP0000036399962.025351.2658aquila_chrysaetos_chrysaetosENSACCP0002002188864.052352.9412
ENSG00000136897homo_sapiensENSP0000036399960.126648.7342ficedula_albicollisENSFALP0000000023858.64247.5309
ENSG00000136897homo_sapiensENSP0000036399956.96246.8354ficedula_albicollisENSFALP0000002799651.136442.0455
ENSG00000136897homo_sapiensENSP0000036399963.291149.3671coturnix_japonicaENSCJPP0000500119961.728448.1481

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0005739located_in mitochondrion1IDAHomo_sapiens(9606)Component
GO:0005743located_in mitochondrial inner membrane2NAS,TASHomo_sapiens(9606)Component
GO:0005762part_of mitochondrial large ribosomal subunit3IBA,IDA,NASHomo_sapiens(9606)Component
GO:0005829located_in cytosol1IDAHomo_sapiens(9606)Component
GO:0032543involved_in mitochondrial translation1NASHomo_sapiens(9606)Process

Expression