Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases N.A.
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions N.A.
Localizations Nucleoli
BulkPerturb-seq

Description

Ensembl ID ENSG00000135932 Gene ID 51719 Accession 20292
Symbol CAB39 Alias MO25;CGI-66 Full Name calcium binding protein 39
Status Confidence Length 108234 bases Strand Plus strand
Position 2 : 230712842 - 230821075 RNA binding domain N.A.
Summary Enables kinase binding activity and protein serine/threonine kinase activator activity. Involved in intracellular signal transduction; peptidyl-serine phosphorylation; and positive regulation of protein phosphorylation. Located in extracellular exosome. Implicated in hepatocellular carcinoma. Biomarker of hepatocellular carcinoma and pancreatic cancer. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
CAB39-201 ENST00000258418 3829 341aa ENSP00000258418
CAB39-203 ENST00000410084 1324 341aa ENSP00000386642
CAB39-202 ENST00000409788 1626 341aa ENSP00000386238
CAB39-205 ENST00000484398 552 No protein -
CAB39-204 ENST00000478152 654 No protein -
CAB39-206 ENST00000493540 561 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005576located_in extracellular region1TASHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm2IDA,ISSHomo_sapiens(9606)Component
GO:0005829located_in cytosol1TASHomo_sapiens(9606)Component
GO:0007165involved_in signal transduction1IDAHomo_sapiens(9606)Process
GO:0010800involved_in positive regulation of peptidyl-threonine phosphorylation1IDAHomo_sapiens(9606)Process
GO:0014823involved_in response to activity1IEAHomo_sapiens(9606)Process
GO:0018105involved_in peptidyl-serine phosphorylation1IDAHomo_sapiens(9606)Process
GO:0019900enables kinase binding1IPIHomo_sapiens(9606)Function
GO:0030018located_in Z disc1IEAHomo_sapiens(9606)Component
GO:0030295enables protein kinase activator activity1IDAHomo_sapiens(9606)Function
GO:0032147involved_in activation of protein kinase activity2IDA,ISSHomo_sapiens(9606)Process
GO:0034774located_in secretory granule lumen1TASHomo_sapiens(9606)Component
GO:0035556involved_in intracellular signal transduction2IBA,IDAHomo_sapiens(9606)Process
GO:0043539enables protein serine/threonine kinase activator activity2IBA,IDAHomo_sapiens(9606)Function
GO:0070062located_in extracellular exosome1HDAHomo_sapiens(9606)Component
GO:0071476involved_in cellular hypotonic response1ICHomo_sapiens(9606)Process
GO:0071902involved_in positive regulation of protein serine/threonine kinase activity1IDAHomo_sapiens(9606)Process
GO:0097066involved_in response to thyroid hormone1IEAHomo_sapiens(9606)Process
GO:1901017involved_in negative regulation of potassium ion transmembrane transporter activity1ICHomo_sapiens(9606)Process
GO:1901380involved_in negative regulation of potassium ion transmembrane transport1ICHomo_sapiens(9606)Process
GO:1902554part_of serine/threonine protein kinase complex3IC,IPI,ISSHomo_sapiens(9606)Component
GO:1904813located_in ficolin-1-rich granule lumen1TASHomo_sapiens(9606)Component

Expression