RBPWorld - a comprehensive database of RNA Binding Proteins

Functions and Diseases

RBP Type	Canonical_RBPs
Diseases	CancerSARS-COV-2
Drug	N.A.
Main interacting RNAs	rRNA
Moonlighting functions	Transmemebrane
Localizations	NucleoliNucleoli rim
BulkPerturb-seq	N.A.

Description

Ensembl ID	ENSG00000134697	Gene ID	29889	Accession	29925
Symbol	GNL2	Alias	NGP1;Nog2;Nug2;Ngp-1;HUMAUANTIG	Full Name	G protein nucleolar 2
Status	Confidence	Length	29122 bases	Strand	Minus strand
Position	1 : 37566816 - 37595937	RNA binding domain	MMR_HSR1
Summary	Enables RNA binding activity. Predicted to be involved in ribosome biogenesis. Located in nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Search:

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000362153	MMR_HSR1	PF01926	1.1e-14	1
ENSP00000441288	MMR_HSR1	PF01926	3.1e-13	1

Showing 1 to 2 of 2 entries

RNA binding proteomes (RBPomes)

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Pubmed ID	Full Name	Cell	Author	Time	Doi
22658674	RIC_PMID22658674_Hela_human	Hela	Alfredo Castello	2012 Jun 8	doi: 10.1016/j.cell.2012.04.031.?Epub 2012 May 31
22658674	RIC_PMID22658674_Hs_HeLa	HeLa	Alfredo Castello?	2012 Jun 8	doi: 10.1016/j.cell.2012.04.031.?Epub 2012 May 31
22681889	RIC_PMID22681889_Hs_HEK293	HEK293	Alexander G Baltz	2012 Jun 8	doi: 10.1016/j.molcel.2012.05.021
25173706	Pclap_PMID25173706_Hs_HEK293	HEK293	Katharina Kramer	2014 Oct;11	doi: 10.1038/nmeth.3092.?Epub 2014 Aug 31
26632259	RIC_PMID26632259._Hs_HuH7	HuH7	Benedikt M Beckmann	2015 Dec 3	doi: 10.1038/ncomms10127.
27040163	serIC_PMID27040163_Hs_K562	K562	Thomas Conrad?	2016 Apr 4	doi: 10.1038/ncomms11212
27040163	serIC_PMID27040163_Hs_K562.1	K562	Thomas Conrad?	2016 Apr 4	doi: 10.1038/ncomms11212
27453046	RBDmap_PMID_27453046_Hs_HeLa	HeLa	Alfredo Castello	2016 Aug 18	doi: 10.1016/j.molcel.2016.06.029.?Epub 2016 Jul 21
29431736	RICK_PMID29431736_Hela_human	Hela	Xichen Bao	2018 Mar	doi: 10.1038/nmeth.4595.?Epub 2018 Feb 12
29431736	RICK_PMID29431736_Hs_HeLa.RICK	HeLa	Xichen Bao	2018 Mar	doi: 10.1038/nmeth.4595.?Epub 2018 Feb 12

Showing 1 to 10 of 30 entries

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Pubmed ID	Title	Author	Time	Journal
No data available in table

Transcripts

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Name	Transcript ID	bp	Protein	Translation ID
GNL2-201	ENST00000373062	2350	731aa	ENSP00000362153
GNL2-202	ENST00000462812	2409	No protein	-
GNL2-203	ENST00000463351	493	No protein	-
GNL2-204	ENST00000469191	533	No protein	-
GNL2-205	ENST00000479255	422	No protein	-
GNL2-206	ENST00000488496	539	No protein	-
GNL2-207	ENST00000489146	630	No protein	-
GNL2-208	ENST00000490029	635	No protein	-
GNL2-209	ENST00000538069	698	233aa	ENSP00000441288

Showing 1 to 9 of 9 entries

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Gene Model

Click here to download ENSG00000134697's gene model file

Phenotypes

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ensgID	Trait	pValue	Pubmed ID
53397	Insulin-Like Growth Factor Binding Protein 3	1.2640000E-005	-

Showing 1 to 1 of 1 entries

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GWAS

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ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID
ENSG00000134697	rs2294875	1	37586844	Lung function (FEV1/FVC)	30595370		EFO_0004713

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Protein-Protein Interaction (PPI)

Click here to download ENSG00000134697's PPI file

Paralogs

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Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000134697	homo_sapiens	ENSP00000354091	41.4089	24.055	homo_sapiens	ENSP00000362153	32.9685	19.1518
ENSG00000134697	homo_sapiens	ENSP00000265245	32.6748	16.7173	homo_sapiens	ENSP00000362153	29.4118	15.0479
ENSG00000134697	homo_sapiens	ENSP00000395772	45.3552	25.8652	homo_sapiens	ENSP00000362153	34.0629	19.4254
ENSG00000134697	homo_sapiens	ENSP00000365806	33.1137	17.2982	homo_sapiens	ENSP00000362153	27.4966	14.3639
ENSG00000134697	homo_sapiens	ENSP00000264230	23.3524	11.6046	homo_sapiens	ENSP00000362153	22.2982	11.0807
ENSG00000134697	homo_sapiens	ENSP00000323047	40.1198	23.6527	homo_sapiens	ENSP00000362153	18.3311	10.8071

Showing 1 to 6 of 6 entries

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Orthologs

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Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000134697	homo_sapiens	ENSP00000362153	99.1792	98.9056	nomascus_leucogenys	ENSNLEP00000014130	99.3151	99.0411
ENSG00000134697	homo_sapiens	ENSP00000362153	99.8632	99.5896	pan_paniscus	ENSPPAP00000000435	91.9395	91.6877
ENSG00000134697	homo_sapiens	ENSP00000362153	99.316	98.7688	pongo_abelii	ENSPPYP00000001765	91.5511	91.0467
ENSG00000134697	homo_sapiens	ENSP00000362153	99.5896	99.316	pan_troglodytes	ENSPTRP00000000969	99.5896	99.316
ENSG00000134697	homo_sapiens	ENSP00000362153	99.5896	99.1792	gorilla_gorilla	ENSGGOP00000007538	99.5896	99.1792
ENSG00000134697	homo_sapiens	ENSP00000362153	84.6785	76.4706	ornithorhynchus_anatinus	ENSOANP00000003260	83.0872	75.0336
ENSG00000134697	homo_sapiens	ENSP00000362153	87.1409	78.6594	sarcophilus_harrisii	ENSSHAP00000014360	88.2271	79.6399
ENSG00000134697	homo_sapiens	ENSP00000362153	71.409	64.7059	notamacropus_eugenii	ENSMEUP00000013828	83.3866	75.5591
ENSG00000134697	homo_sapiens	ENSP00000362153	64.5691	61.2859	choloepus_hoffmanni	ENSCHOP00000008418	65.1934	61.8785
ENSG00000134697	homo_sapiens	ENSP00000362153	92.4761	88.5089	dasypus_novemcinctus	ENSDNOP00000012765	92.9849	88.9959

Showing 1 to 10 of 203 entries

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Gene Ontology

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Go ID	Go term	No. evidence	Entries	Species	Category
GO:0005730	is_active_in nucleolus	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0003723	enables RNA binding	1	HDA	Homo_sapiens(9606)	Function
GO:0003924	enables GTPase activity	1	NAS	Homo_sapiens(9606)	Function
GO:0005525	enables GTP binding	1	NAS	Homo_sapiens(9606)	Function
GO:0005634	located_in nucleus	1	TAS	Homo_sapiens(9606)	Component
GO:0008150	involved_in biological_process	1	ND	Homo_sapiens(9606)	Process
GO:0016020	located_in membrane	1	HDA	Homo_sapiens(9606)	Component
GO:0042254	involved_in ribosome biogenesis	1	IEA	Homo_sapiens(9606)	Process

Showing 1 to 8 of 8 entries

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Welcome to

RBP World!

Functions and Diseases

Description

RNA binding domains (RBDs)

RNA binding proteomes (RBPomes)

Literatures on RNA binding capacity

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

Protein-Protein Interaction (PPI)

Paralogs

Orthologs

Gene Ontology

Expression