Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases N.A.
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions N.A.
Localizations Nucleoli
BulkPerturb-seq

Description

Ensembl ID ENSG00000132254 Gene ID 23647 Accession 17160
Symbol ARFIP2 Alias POR1 Full Name ADP ribosylation factor interacting protein 2
Status Confidence Length 6797 bases Strand Minus strand
Position 11 : 6474683 - 6481479 RNA binding domain N.A.
Summary Enables several functions, including GTP-dependent protein binding activity; membrane curvature sensor activity; and phosphatidylinositol-4-phosphate binding activity. Involved in actin cytoskeleton organization. Located in cell cortex; ruffle; and trans-Golgi network membrane. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
ARFIP2-210 ENST00000614314 3846 374aa ENSP00000484121
ARFIP2-201 ENST00000254584 2543 341aa ENSP00000254584
ARFIP2-202 ENST00000396777 1763 341aa ENSP00000379998
ARFIP2-209 ENST00000531037 1560 159aa ENSP00000434564
ARFIP2-204 ENST00000445086 1300 256aa ENSP00000391427
ARFIP2-203 ENST00000423813 1430 303aa ENSP00000398375
ARFIP2-205 ENST00000525235 852 202aa ENSP00000434124
ARFIP2-208 ENST00000530410 971 No protein -
ARFIP2-207 ENST00000529847 920 No protein -
ARFIP2-206 ENST00000525329 563 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000423involved_in mitophagy1IMPHomo_sapiens(9606)Process
GO:0001726located_in ruffle1IMPHomo_sapiens(9606)Component
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005525enables GTP binding1TASHomo_sapiens(9606)Function
GO:0005543enables phospholipid binding1IBAHomo_sapiens(9606)Function
GO:0005730located_in nucleolus1IDAHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005794located_in Golgi apparatus1IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol1TASHomo_sapiens(9606)Component
GO:0005886located_in plasma membrane1TASHomo_sapiens(9606)Component
GO:0005938located_in cell cortex1IDAHomo_sapiens(9606)Component
GO:0006886involved_in intracellular protein transport1IBAHomo_sapiens(9606)Process
GO:0007264involved_in small GTPase mediated signal transduction1TASHomo_sapiens(9606)Process
GO:0019904enables protein domain specific binding1IEAHomo_sapiens(9606)Function
GO:0030032involved_in lamellipodium assembly1TASHomo_sapiens(9606)Process
GO:0030036involved_in actin cytoskeleton organization1IMPHomo_sapiens(9606)Process
GO:0030742enables GTP-dependent protein binding1IPIHomo_sapiens(9606)Function
GO:0031267enables small GTPase binding1TASHomo_sapiens(9606)Function
GO:0031529involved_in ruffle organization1TASHomo_sapiens(9606)Process
GO:0032588is_active_in trans-Golgi network membrane2IBA,IDAHomo_sapiens(9606)Component
GO:0034315involved_in regulation of Arp2/3 complex-mediated actin nucleation1IBAHomo_sapiens(9606)Process
GO:0034497involved_in protein localization to phagophore assembly site1IMPHomo_sapiens(9606)Process
GO:0042802enables identical protein binding1IPIHomo_sapiens(9606)Function
GO:0045296enables cadherin binding1HDAHomo_sapiens(9606)Function
GO:0070273enables phosphatidylinositol-4-phosphate binding1IDAHomo_sapiens(9606)Function
GO:0140090enables membrane curvature sensor activity1IDAHomo_sapiens(9606)Function

Expression