RBP Type
Non-canonical_RBPs
Diseases
SARS-COV-2
Drug
N.A.
Main interacting RNAs
N.A.
Moonlighting functions
Metabolic enzyme
Localizations
N.A.
BulkPerturb-seq
Ensembl ID ENSG00000130175 Gene ID
5589
Accession
9411
Symbol
PRKCSH
Alias
GIIB;PCLD;PLD1;80K-H;G19P1;PCLD1;PKCSH;AGE-R2;GIIbeta;VASAP-60;GluIIbeta
Full Name
protein kinase C substrate 80K-H
Status
Confidence
Length
15685 bases
Strand
Plus strand
Position
19 : 11435284 - 11450968
RNA binding domain
N.A.
Summary
This gene encodes the beta-subunit of glucosidase II, an N-linked glycan-processing enzyme in the endoplasmic reticulum. The encoded protein is an acidic phosphoprotein known to be a substrate for protein kinase C. Mutations in this gene have been associated with the autosomal dominant polycystic liver disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
Name
Transcript ID
bp
Protein
Translation ID
PRKCSH-221
ENST00000676823
814
171aa
ENSP00000503072
PRKCSH-214
ENST00000591946
569
62aa
ENSP00000464835
PRKCSH-208
ENST00000589126
625
168aa
ENSP00000467566
PRKCSH-207
ENST00000588269
557
132aa
ENSP00000465889
PRKCSH-206
ENST00000587509
545
140aa
ENSP00000465821
PRKCSH-220
ENST00000593104
545
No protein
-
PRKCSH-218
ENST00000593053
588
No protein
-
PRKCSH-212
ENST00000591462
2063
525aa
ENSP00000465489
PRKCSH-217
ENST00000592741
2100
535aa
ENSP00000466134
PRKCSH-222
ENST00000677123
2096
535aa
ENSP00000503163
PRKCSH-219
ENST00000593101
578
144aa
ENSP00000465047
PRKCSH-205
ENST00000587327
2189
525aa
ENSP00000466012
PRKCSH-209
ENST00000589838
1898
528aa
ENSP00000465461
PRKCSH-210
ENST00000589990
567
No protein
-
PRKCSH-201
ENST00000585325
598
No protein
-
PRKCSH-216
ENST00000592445
598
No protein
-
PRKCSH-202
ENST00000585540
501
No protein
-
PRKCSH-203
ENST00000586486
1613
200aa
ENSP00000465948
PRKCSH-204
ENST00000587290
780
No protein
-
PRKCSH-211
ENST00000590098
795
No protein
-
PRKCSH-215
ENST00000592435
358
No protein
-
PRKCSH-213
ENST00000591510
591
No protein
-
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0001889 involved_in liver development 1 IBA Homo_sapiens(9606) Process GO:0005080 enables protein kinase C binding 1 IPI Homo_sapiens(9606) Function GO:0005509 enables calcium ion binding 1 IEA Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005783 located_in endoplasmic reticulum 1 IDA Homo_sapiens(9606) Component GO:0005788 located_in endoplasmic reticulum lumen 2 NAS,TAS Homo_sapiens(9606) Component GO:0006491 involved_in N-glycan processing 2 IBA,IDA Homo_sapiens(9606) Process GO:0017177 part_of glucosidase II complex 3 IBA,IDA,IPI Homo_sapiens(9606) Component GO:0035556 involved_in intracellular signal transduction 1 NAS Homo_sapiens(9606) Process GO:0043231 located_in intracellular membrane-bounded organelle 1 IMP Homo_sapiens(9606) Component GO:0044325 enables transmembrane transporter binding 1 IPI Homo_sapiens(9606) Function GO:0051219 enables phosphoprotein binding 1 IPI Homo_sapiens(9606) Function
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