Functions and Diseases

RBP Type Canonical_RBPs
Diseases N.A.
Drug Drug
Main interacting RNAs N.A.
Moonlighting functions N.A.
Localizations Nucleoli
BulkPerturb-seq

Description

Ensembl ID ENSG00000129484 Gene ID 10038 Accession 272
Symbol PARP2 Alias ARTD2;ADPRT2;PARP-2;ADPRTL2;ADPRTL3;pADPRT-2 Full Name poly(ADP-ribose) polymerase 2
Status Confidence Length 14290 bases Strand Plus strand
Position 14 : 20343615 - 20357904 RNA binding domain PARP
Summary This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

RNA binding proteomes (RBPomes)

Literatures on RNA binding capacity

Transcripts

Phenotypes

Protein-Protein Interaction (PPI)

Paralogs

Orthologs

Gene Ontology

Expression