Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs ncRNA
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000128191 Gene ID 54487 Accession 2847
Symbol DGCR8 Alias Gy1;pasha;DGCRK6;C22orf12 Full Name DGCR8 microprocessor complex subunit
Status Confidence Length 31652 bases Strand Plus strand
Position 22 : 20080221 - 20111872 RNA binding domain dsrm
Summary This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000516053 dsrm PF00035 5e-22 1
ENSP00000516053 dsrm PF00035 5e-22 2
ENSP00000516052 dsrm PF00035 6.7e-21 1
ENSP00000516052 dsrm PF00035 6.7e-21 2
ENSP00000263209 dsrm PF00035 2e-20 1
ENSP00000263209 dsrm PF00035 2e-20 2
ENSP00000409625 dsrm PF00035 2e-20 1
ENSP00000409625 dsrm PF00035 2e-20 2
ENSP00000384726 dsrm PF00035 3.6e-05 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
34914716 Sequencing of Argonaute-bound microRNA/mRNA hybrids reveals regulation of the unfolded protein response by microRNA-320a. J Christopher Fields 2021-12-01 PLoS genetics
32994184 Human disease-associated single nucleotide polymorphism changes the orientation of DROSHA on pri-mir-146a. Truc Cong Le 2020-12-01 RNA (New York, N.Y.)
32411322 Crosstalk of MicroRNAs and Oxidative Stress in the Pathogenesis of Cancer. Can Lu 2020-01-01 Oxidative medicine and cellular longevity
31614644 The Role of MicroRNAs in Selected Forms of Glomerulonephritis. Magdalena Nalewajska 2019-10-11 International journal of molecular sciences
25326327 Global identification of target recognition and cleavage by the Microprocessor in human ES cells. Youngmo Seong 2014-11-10 Nucleic acids research
27766492 CO and NO bind to Fe(II) DiGeorge critical region 8 heme but do not restore primary microRNA processing activity. P Judy Hines 2016-12-01 Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry
24574967 MicroRNAs regulate neuronal plasticity and are involved in pain mechanisms. Sara Elramah 2014-01-01 Frontiers in cellular neuroscience
32808488 Roles of N6 -methyladenosine (m6 A) RNA modifications in urological cancers. Xiao Wang 2020-09-01 Journal of cellular and molecular medicine
25823356 Silencing the double-stranded RNA binding protein DGCR8 inhibits ovarian cancer cell proliferation, migration, and invasion. Yuqi Guo 2015-03-01 Pharmaceutical research
32858958 Prediction and Analysis of SARS-CoV-2-Targeting MicroRNA in Human Lung Epithelium. Tak-Sum Jonathan Chow 2020-08-26 Genes
25814653 MicroRNAs in cardiovascular disease: an introduction for clinicians. R P Simon Romaine 2015-06-01 Heart (British Cardiac Society)
22234702 Epigenetic modifications in cardiovascular disease. M Johan Lorenzen 2012-03-01 Basic research in cardiology
24786770 Drosha promotes splicing of a pre-microRNA-like alternative exon. A Mallory Havens 2014-05-01 PLoS genetics
23324117 A brief primer on microRNAs and their roles in angiogenesis. Sudarshan Anand 2013-01-16 Vascular cell
31052302 Non-Coding RNA Networks in ALK-Positive Anaplastic-Large Cell Lymphoma. Steffen Fuchs 2019-04-30 International journal of molecular sciences
34685720 The Roles of Extracellular Vesicles in Malignant Melanoma. Ying-Chen Cheng 2021-10-14 Cells
32188489 CircLONP2 enhances colorectal carcinoma invasion and metastasis through modulating the maturation and exosomal dissemination of microRNA-17. Kai Han 2020-03-18 Molecular cancer
30022983 Potential Role of MicroRNAs in the Regulation of Antiviral Responses to Influenza Infection. Hiep Thi Nguyen 2018-01-01 Frontiers in immunology
32297952 Uncovering the cellular capacity for intensive and specific feedback self-control of the argonautes and MicroRNA targeting activity. Degeng Wang 2020-05-21 Nucleic acids research
18631387 Non-protein coding RNA biomarkers and differential expression in cancers: a review. Massimo Mallardo 2008-07-16 Journal of experimental & clinical cancer research : CR
33668203 The Implications of ncRNAs in the Development of Human Diseases. Elena López-Jiménez 2021-02-24 Non-coding RNA
34572067 The Roles of the Let-7 Family of MicroRNAs in the Regulation of Cancer Stemness. Yuxi Ma 2021-09-14 Cells
27248057 Design of a bioactive small molecule that targets r(AUUCU) repeats in spinocerebellar ataxia 10. Wang-Yong Yang 2016-06-01 Nature communications
28529819 In situ Detection of MicroRNAs: The Art of MicroRNA Research in Human Diseases. Duo Zhang 2015-01-01 Journal of cytology & histology
28380355 DGCR8 Mediates Repair of UV-Induced DNA Damage Independently of RNA Processing. C Philamer Calses 2017-04-04 Cell reports
24078866 Simultaneous Detection of Different MicroRNA Types Using the ZIP-Code Array System. U Sonja Weishaupt 2013-01-01 Journal of nucleic acids
27625393 Identifying proteins that bind to specific RNAs - focus on simple repeat expansion diseases. Magdalena Jazurek 2016-11-02 Nucleic acids research
25660948 Signaling-mediated regulation of MicroRNA processing. Jia Shen 2015-03-01 Cancer research
33735606 POINT technology illuminates the processing of polymerase-associated intact nascent transcripts. Rui Sousa-Luís 2021-05-06 Molecular cell
31835460 NF-κB and MicroRNA Deregulation Mediated by HTLV-1 Tax and HBZ. Stefania Fochi 2019-12-10 Pathogens (Basel, Switzerland)
28250048 MicroRNAs in the etiology of colorectal cancer: pathways and clinical implications. M Ashlee Strubberg 2017-03-01 Disease models & mechanisms
22138056 Dgcr8 controls neural crest cells survival in cardiovascular development. Elik Chapnik 2012-02-01 Developmental biology
23995758 The Microprocessor controls the activity of mammalian retrotransposons. R Sara Heras 2013-10-01 Nature structural & molecular biology
17118159 Non coding RNA and brain. Carlo Presutti 2006-10-30 BMC neuroscience
33953838 Therapeutic Value of miRNAs in Coronary Artery Disease. Sayed Md MS Ali 2021-01-01 Oxidative medicine and cellular longevity

Transcripts

Name Transcript ID bp Protein Translation ID
DGCR8-210 ENST00000704820 3947 580aa ENSP00000516052
DGCR8-201 ENST00000351989 4506 773aa ENSP00000263209
DGCR8-211 ENST00000704821 2882 303aa ENSP00000516053
DGCR8-202 ENST00000407755 4359 740aa ENSP00000384726
DGCR8-203 ENST00000457069 4480 773aa ENSP00000409625
DGCR8-208 ENST00000495826 4695 No protein -
DGCR8-209 ENST00000498171 3661 No protein -
DGCR8-206 ENST00000491892 630 No protein -
DGCR8-207 ENST00000495351 508 No protein -
DGCR8-205 ENST00000485802 555 No protein -
DGCR8-204 ENST00000475941 2669 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000128191

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000128191homo_sapiensENSP0000026320999.870699.7413nomascus_leucogenysENSNLEP0000000686599.870699.7413
ENSG00000128191homo_sapiensENSP00000263209100100pan_paniscusENSPPAP00000033290100100
ENSG00000128191homo_sapiensENSP0000026320910099.8706pongo_abeliiENSPPYP0000001293010099.8706
ENSG00000128191homo_sapiensENSP00000263209100100pan_troglodytesENSPTRP00000024242100100
ENSG00000128191homo_sapiensENSP0000026320910099.8706gorilla_gorillaENSGGOP0000000077010099.8706
ENSG00000128191homo_sapiensENSP0000026320984.346780.207ornithorhynchus_anatinusENSOANP0000003964186.129581.9022
ENSG00000128191homo_sapiensENSP0000026320988.745182.5356sarcophilus_harrisiiENSSHAP0000002944988.745182.5356
ENSG00000128191homo_sapiensENSP0000026320981.500673.2212notamacropus_eugeniiENSMEUP0000000096183.554475.0663
ENSG00000128191homo_sapiensENSP0000026320957.050551.8758choloepus_hoffmanniENSCHOP0000000585676.034569.1379
ENSG00000128191homo_sapiensENSP0000026320996.765894.5666dasypus_novemcinctusENSDNOP0000000800396.765894.5666
ENSG00000128191homo_sapiensENSP0000026320984.08882.4062erinaceus_europaeusENSEEUP0000001078887.131485.3887
ENSG00000128191homo_sapiensENSP0000026320960.025958.2147echinops_telfairiENSETEP0000001296760.025958.2147
ENSG00000128191homo_sapiensENSP0000026320999.741399.6119callithrix_jacchusENSCJAP0000001994099.741399.6119
ENSG00000128191homo_sapiensENSP0000026320999.870699.8706cercocebus_atysENSCATP0000001310499.870699.8706
ENSG00000128191homo_sapiensENSP0000026320999.482599.0944macaca_fascicularisENSMFAP0000004324298.21297.8289
ENSG00000128191homo_sapiensENSP0000026320999.482599.0944macaca_mulattaENSMMUP0000006792198.21297.8289
ENSG00000128191homo_sapiensENSP0000026320999.611999.6119macaca_nemestrinaENSMNEP0000000213499.099199.0991
ENSG00000128191homo_sapiensENSP0000026320999.741399.7413papio_anubisENSPANP0000001519499.741399.7413
ENSG00000128191homo_sapiensENSP0000026320999.870699.8706mandrillus_leucophaeusENSMLEP0000001230499.870699.8706
ENSG00000128191homo_sapiensENSP0000026320992.108790.0388tursiops_truncatusENSTTRP0000000769392.22890.1554
ENSG00000128191homo_sapiensENSP0000026320991.073789.6507vulpes_vulpesENSVVUP0000003531890.488489.0745
ENSG00000128191homo_sapiensENSP0000026320992.884991.4618mus_spretusMGP_SPRETEiJ_P004262895.605994.1411
ENSG00000128191homo_sapiensENSP0000026320997.283395.4722equus_asinusENSEASP0000501504797.283395.4722
ENSG00000128191homo_sapiensENSP0000026320993.531790.0388capra_hircusENSCHIP0000002155294.633591.0995
ENSG00000128191homo_sapiensENSP0000026320997.930196.2484loxodonta_africanaENSLAFP0000001148897.930196.2484
ENSG00000128191homo_sapiensENSP0000026320997.54296.3777panthera_leoENSPLOP0000002715397.54296.3777
ENSG00000128191homo_sapiensENSP0000026320997.412796.2484ailuropoda_melanoleucaENSAMEP0000001235597.412796.2484
ENSG00000128191homo_sapiensENSP0000026320993.531790.5563bos_indicus_hybridENSBIXP0000501396895.131692.1053
ENSG00000128191homo_sapiensENSP0000026320996.377794.8254oryctolagus_cuniculusENSOCUP0000000313696.377794.8254
ENSG00000128191homo_sapiensENSP0000026320997.153995.2135equus_caballusENSECAP0000000725397.153995.2135
ENSG00000128191homo_sapiensENSP0000026320997.412796.119canis_lupus_familiarisENSCAFP0084503860797.412796.119
ENSG00000128191homo_sapiensENSP0000026320997.54296.3777panthera_pardusENSPPRP0000002742097.54296.3777
ENSG00000128191homo_sapiensENSP0000026320997.671496.3777marmota_marmota_marmotaENSMMMP0000000481997.671496.3777
ENSG00000128191homo_sapiensENSP0000026320997.153994.9547balaenoptera_musculusENSBMSP0001002526197.153994.9547
ENSG00000128191homo_sapiensENSP0000026320997.54295.9896cavia_porcellusENSCPOP0000002871797.54295.9896
ENSG00000128191homo_sapiensENSP0000026320997.671496.5071felis_catusENSFCAP0000002761997.671496.5071
ENSG00000128191homo_sapiensENSP0000026320997.412796.119ursus_americanusENSUAMP0000001349697.412796.119
ENSG00000128191homo_sapiensENSP0000026320988.874582.5356monodelphis_domesticaENSMODP0000001294888.759782.4289
ENSG00000128191homo_sapiensENSP0000026320990.81587.7102monodon_monocerosENSMMNP0001500294790.115587.0347
ENSG00000128191homo_sapiensENSP0000026320995.860393.5317sus_scrofaENSSSCP0000001080891.821689.5911
ENSG00000128191homo_sapiensENSP0000026320999.094497.9301microcebus_murinusENSMICP0000003642899.094497.9301
ENSG00000128191homo_sapiensENSP0000026320997.54295.7309octodon_degusENSODEP0000002234497.54295.7309
ENSG00000128191homo_sapiensENSP0000026320997.024695.4722jaculus_jaculusENSJJAP0000001062297.024695.4722
ENSG00000128191homo_sapiensENSP0000026320993.143689.5213ovis_aries_rambouilletENSOARP0002000877394.861791.1726
ENSG00000128191homo_sapiensENSP0000026320997.412796.119ursus_maritimusENSUMAP0000000979097.412796.119
ENSG00000128191homo_sapiensENSP0000026320994.437392.4968ochotona_princepsENSOPRP0000000774895.052193.099
ENSG00000128191homo_sapiensENSP0000026320994.954792.7555delphinapterus_leucasENSDLEP0000002789797.347595.0928
ENSG00000128191homo_sapiensENSP0000026320996.507195.0841mus_caroliMGP_CAROLIEiJ_P004077696.507195.0841
ENSG00000128191homo_sapiensENSP0000026320996.636595.2135mus_musculusENSMUSP0000000932196.636595.2135
ENSG00000128191homo_sapiensENSP0000026320997.283395.8603dipodomys_ordiiENSDORP0000002761797.283395.8603
ENSG00000128191homo_sapiensENSP0000026320995.213593.9198mustela_putorius_furoENSMPUP0000000397297.612796.2865
ENSG00000128191homo_sapiensENSP0000026320999.611999.2238aotus_nancymaaeENSANAP0000000169199.611999.2238
ENSG00000128191homo_sapiensENSP0000026320999.870699.7413saimiri_boliviensis_boliviensisENSSBOP0000001236799.870699.7413
ENSG00000128191homo_sapiensENSP0000026320937.904337.1281vicugna_pacosENSVPAP0000000856849.161148.1544
ENSG00000128191homo_sapiensENSP0000026320999.870699.8706chlorocebus_sabaeusENSCSAP0000000817999.870699.8706
ENSG00000128191homo_sapiensENSP0000026320979.689578.2665tupaia_belangeriENSTBEP000000062198078.5714
ENSG00000128191homo_sapiensENSP0000026320996.765895.2135mesocricetus_auratusENSMAUP0000000064296.765895.2135
ENSG00000128191homo_sapiensENSP0000026320997.024694.9547phocoena_sinusENSPSNP0000003033897.024694.9547
ENSG00000128191homo_sapiensENSP0000026320996.765894.696camelus_dromedariusENSCDRP0000502605196.765894.696
ENSG00000128191homo_sapiensENSP0000026320996.895295.9896carlito_syrichtaENSTSYP0000001539296.025695.1282
ENSG00000128191homo_sapiensENSP0000026320997.412796.2484panthera_tigris_altaicaENSPTIP0000001013797.412796.2484
ENSG00000128191homo_sapiensENSP0000026320995.989694.4373rattus_norvegicusENSRNOP0000000258195.989694.4373
ENSG00000128191homo_sapiensENSP0000026320999.094497.9301prolemur_simusENSPSMP0000000300299.094497.9301
ENSG00000128191homo_sapiensENSP0000026320996.895295.4722microtus_ochrogasterENSMOCP0000001558996.895295.4722
ENSG00000128191homo_sapiensENSP0000026320996.765895.2135sorex_araneusENSSARP0000000839696.765895.2135
ENSG00000128191homo_sapiensENSP0000026320996.895295.3428peromyscus_maniculatus_bairdiiENSPEMP0000002023396.895295.3428
ENSG00000128191homo_sapiensENSP0000026320991.203188.2277bos_mutusENSBMUP0000000597678.77176.2011
ENSG00000128191homo_sapiensENSP0000026320994.178592.4968mus_spicilegusENSMSIP0000002423691.228189.599
ENSG00000128191homo_sapiensENSP0000026320996.895295.4722cricetulus_griseus_chok1gshdENSCGRP0000100122696.895295.4722
ENSG00000128191homo_sapiensENSP0000026320987.063485.7697pteropus_vampyrusENSPVAP0000001480087.289285.9922
ENSG00000128191homo_sapiensENSP0000026320995.472293.7904myotis_lucifugusENSMLUP0000001598996.21994.5241
ENSG00000128191homo_sapiensENSP0000026320988.874582.4062vombatus_ursinusENSVURP0001001918888.874582.4062
ENSG00000128191homo_sapiensENSP0000026320997.283395.9896rhinolophus_ferrumequinumENSRFEP0001003264797.283395.9896
ENSG00000128191homo_sapiensENSP0000026320997.283395.8603neovison_visonENSNVIP0000002945697.283395.8603
ENSG00000128191homo_sapiensENSP0000026320992.23888.357bos_taurusENSBTAP0000005745778.697675.3863
ENSG00000128191homo_sapiensENSP0000026320990.944489.5213heterocephalus_glaber_femaleENSHGLP0000002384596.698895.1857
ENSG00000128191homo_sapiensENSP0000026320999.870699.8706rhinopithecus_bietiENSRBIP0000000321699.870699.8706
ENSG00000128191homo_sapiensENSP0000026320997.412796.119canis_lupus_dingoENSCAFP0002000956897.412796.119
ENSG00000128191homo_sapiensENSP0000026320997.671496.2484sciurus_vulgarisENSSVLP0000501070797.671496.2484
ENSG00000128191homo_sapiensENSP0000026320986.93480.0776phascolarctos_cinereusENSPCIP0000005311185.171178.4537
ENSG00000128191homo_sapiensENSP0000026320991.979390.2975procavia_capensisENSPCAP0000001495591.979390.2975
ENSG00000128191homo_sapiensENSP0000026320997.153995.7309nannospalax_galiliENSNGAP0000000306597.153995.7309
ENSG00000128191homo_sapiensENSP0000026320992.884990.4269bos_grunniensENSBGRP0000003634787.990285.6618
ENSG00000128191homo_sapiensENSP0000026320997.671496.2484chinchilla_lanigeraENSCLAP0000002030497.671496.2484
ENSG00000128191homo_sapiensENSP0000026320993.014289.7801cervus_hanglu_yarkandensisENSCHYP0000001642594.605391.3158
ENSG00000128191homo_sapiensENSP0000026320995.989693.4023catagonus_wagneriENSCWAP0000001287695.989693.4023
ENSG00000128191homo_sapiensENSP0000026320997.671496.3777ictidomys_tridecemlineatusENSSTOP0000002380297.671496.3777
ENSG00000128191homo_sapiensENSP0000026320998.318297.4127otolemur_garnettiiENSOGAP0000000433898.318297.4127
ENSG00000128191homo_sapiensENSP0000026320910099.6119cebus_imitatorENSCCAP0000003752410099.6119
ENSG00000128191homo_sapiensENSP0000026320997.671496.5071urocitellus_parryiiENSUPAP0001001393297.671496.5071
ENSG00000128191homo_sapiensENSP0000026320993.790490.1682moschus_moschiferusENSMMSP0000000864695.394791.7105
ENSG00000128191homo_sapiensENSP0000026320999.870699.8706rhinopithecus_roxellanaENSRROP0000001117999.870699.8706
ENSG00000128191homo_sapiensENSP0000026320996.507195.0841mus_pahariMGP_PahariEiJ_P002816296.507195.0841
ENSG00000128191homo_sapiensENSP0000026320999.353298.3182propithecus_coquereliENSPCOP0000002612099.353298.3182
ENSG00000128191homo_sapiensENSP0000026320937.516221.0867caenorhabditis_elegansT22A3.5a.138.615221.7044
ENSG00000128191homo_sapiensENSP0000026320941.009127.555drosophila_melanogasterFBpp008518149.376933.1776
ENSG00000128191homo_sapiensENSP0000026320916.817611.2549ciona_intestinalisENSCINP0000001660958.558639.1892
ENSG00000128191homo_sapiensENSP0000026320914.74778.7969ciona_intestinalisENSCINP0000003599346.913627.9835
ENSG00000128191homo_sapiensENSP0000026320951.099638.4217eptatretus_burgeriENSEBUP0000001925853.52340.2439
ENSG00000128191homo_sapiensENSP0000026320981.759471.6688callorhinchus_miliiENSCMIP000000314828070.1266
ENSG00000128191homo_sapiensENSP0000026320983.441175.5498latimeria_chalumnaeENSLACP0000001986283.657675.7458
ENSG00000128191homo_sapiensENSP0000026320984.217376.4554lepisosteus_oculatusENSLOCP0000000293582.093374.5271
ENSG00000128191homo_sapiensENSP0000026320979.818971.022clupea_harengusENSCHAP0000006162879.001370.2945
ENSG00000128191homo_sapiensENSP0000026320979.689571.022danio_rerioENSDARP0000011337578.772470.2046
ENSG00000128191homo_sapiensENSP0000026320978.137169.8577carassius_auratusENSCARP0000008199577.336769.1421
ENSG00000128191homo_sapiensENSP0000026320980.20772.7038carassius_auratusENSCARP0000013015778.184170.8701
ENSG00000128191homo_sapiensENSP0000026320980.983273.2212astyanax_mexicanusENSAMXP0000001794679.745272.1019
ENSG00000128191homo_sapiensENSP0000026320978.525271.022ictalurus_punctatusENSIPUP0000002483579.036571.4844
ENSG00000128191homo_sapiensENSP0000026320980.20771.4101esox_luciusENSELUP0000006027377.987469.434
ENSG00000128191homo_sapiensENSP0000026320979.948272.0569electrophorus_electricusENSEEEP0000004526480.051872.1503
ENSG00000128191homo_sapiensENSP0000026320980.336371.2807oncorhynchus_kisutchENSOKIP0000502278475.916967.3594
ENSG00000128191homo_sapiensENSP0000026320981.112571.9276oncorhynchus_kisutchENSOKIP0000500042078.473169.587
ENSG00000128191homo_sapiensENSP0000026320979.948271.2807oncorhynchus_mykissENSOMYP0000006344876.865768.5323
ENSG00000128191homo_sapiensENSP0000026320981.241972.0569oncorhynchus_mykissENSOMYP0000010658379.093270.1511
ENSG00000128191homo_sapiensENSP0000026320980.077671.4101salmo_salarENSSSAP0000011946280.181471.5026
ENSG00000128191homo_sapiensENSP0000026320980.077671.5395salmo_salarENSSSAP0000008979576.608968.4406
ENSG00000128191homo_sapiensENSP0000026320980.724472.1863salmo_truttaENSSTUP0000006625278.195569.9248
ENSG00000128191homo_sapiensENSP0000026320980.465771.4101salmo_truttaENSSTUP0000011401778.337569.5214
ENSG00000128191homo_sapiensENSP0000026320973.738766.2354gadus_morhuaENSGMOP0000006367076.203268.4492
ENSG00000128191homo_sapiensENSP0000026320979.301470.8926fundulus_heteroclitusENSFHEP0000000600778.893270.5277
ENSG00000128191homo_sapiensENSP0000026320977.102267.6585poecilia_reticulataENSPREP0000002792275.730666.4549
ENSG00000128191homo_sapiensENSP0000026320979.560270.1164xiphophorus_maculatusENSXMAP0000004119678.443969.1327
ENSG00000128191homo_sapiensENSP0000026320978.266569.3402oryzias_latipesENSORLP0000001899778.673669.7009
ENSG00000128191homo_sapiensENSP0000026320980.724471.4101cyclopterus_lumpusENSCLMP0000501081476.564467.7301
ENSG00000128191homo_sapiensENSP0000026320979.560270.1164oreochromis_niloticusENSONIP0000001393879.150669.7555
ENSG00000128191homo_sapiensENSP0000026320980.20771.1514haplochromis_burtoniENSHBUP0000000706179.283970.3325
ENSG00000128191homo_sapiensENSP0000026320980.20771.1514astatotilapia_callipteraENSACLP0000002914979.283970.3325
ENSG00000128191homo_sapiensENSP0000026320974.644265.718sparus_aurataENSSAUP0001006385272.761764.0605
ENSG00000128191homo_sapiensENSP0000026320978.395968.9521lates_calcariferENSLCAP0001003983877.001367.7255
ENSG00000128191homo_sapiensENSP0000026320986.028577.2316xenopus_tropicalisENSXETP0000001385786.139977.3316
ENSG00000128191homo_sapiensENSP0000026320990.556383.5705chrysemys_picta_belliiENSCPBP0000002377990.556383.5705
ENSG00000128191homo_sapiensENSP0000026320989.39282.2768sphenodon_punctatusENSSPUP0000001949389.39282.2768
ENSG00000128191homo_sapiensENSP0000026320975.161770.2458crocodylus_porosusENSCPRP0000500035588.163982.3976
ENSG00000128191homo_sapiensENSP0000026320988.098381.63laticauda_laticaudataENSLLTP0000001089688.098381.63
ENSG00000128191homo_sapiensENSP0000026320988.098382.1475notechis_scutatusENSNSUP0000002886788.098382.1475
ENSG00000128191homo_sapiensENSP0000026320988.227782.1475pseudonaja_textilisENSPTXP0000002674788.227782.1475
ENSG00000128191homo_sapiensENSP0000026320990.426984.088anas_platyrhynchos_platyrhynchosENSAPLP0000000381690.193683.871
ENSG00000128191homo_sapiensENSP0000026320990.297583.8292gallus_gallusENSGALP0001002971990.064583.6129
ENSG00000128191homo_sapiensENSP0000026320988.35781.5006meleagris_gallopavoENSMGAP0000003130284.113377.5862
ENSG00000128191homo_sapiensENSP0000026320989.780183.1824serinus_canariaENSSCAP0000000607289.548482.9677
ENSG00000128191homo_sapiensENSP0000026320990.038883.4411parus_majorENSPMJP0000001894089.806483.2258
ENSG00000128191homo_sapiensENSP0000026320989.521382.5356anolis_carolinensisENSACAP0000000789789.521382.5356
ENSG00000128191homo_sapiensENSP0000026320980.20771.2807neolamprologus_brichardiENSNBRP0000000304479.283970.4604
ENSG00000128191homo_sapiensENSP0000026320986.287279.9482naja_najaENSNNAP0000001966686.51180.1556
ENSG00000128191homo_sapiensENSP0000026320989.262682.4062podarcis_muralisENSPMRP0000002498989.262682.4062
ENSG00000128191homo_sapiensENSP0000026320985.381679.1721geospiza_fortisENSGFOP0000001264289.068882.5911
ENSG00000128191homo_sapiensENSP0000026320989.909483.4411taeniopygia_guttataENSTGUP0000001876189.677483.2258
ENSG00000128191homo_sapiensENSP0000026320983.311875.5498erpetoichthys_calabaricusENSECRP0000003143481.006373.4591
ENSG00000128191homo_sapiensENSP0000026320979.818971.2807kryptolebias_marmoratusENSKMAP0000001214078.69970.2806
ENSG00000128191homo_sapiensENSP0000026320988.745182.7943salvator_merianaeENSSMRP0000001121588.860182.9016
ENSG00000128191homo_sapiensENSP0000026320979.172170.2458oryzias_javanicusENSOJAP0000004901379.377470.428
ENSG00000128191homo_sapiensENSP0000026320979.948271.1514amphilophus_citrinellusENSACIP0000002597179.028170.3325
ENSG00000128191homo_sapiensENSP0000026320980.20771.5395dicentrarchus_labraxENSDLAP0000505037879.283970.7161
ENSG00000128191homo_sapiensENSP0000026320979.948271.1514amphiprion_perculaENSAPEP0000000691979.332570.6033
ENSG00000128191homo_sapiensENSP0000026320976.972868.0466oryzias_sinensisENSOSIP0000001141377.373268.4005
ENSG00000128191homo_sapiensENSP0000026320917.464416.3001pelodiscus_sinensisENSPSIP0000000442096.428690
ENSG00000128191homo_sapiensENSP0000026320945.407539.4567pelodiscus_sinensisENSPSIP0000001597882.201471.4286
ENSG00000128191homo_sapiensENSP0000026320989.262682.5356pelodiscus_sinensisENSPSIP0000000232090.078383.2898
ENSG00000128191homo_sapiensENSP0000026320990.81583.9586gopherus_evgoodeiENSGEVP0000502971590.697783.8501
ENSG00000128191homo_sapiensENSP0000026320984.734877.3609chelonoidis_abingdoniiENSCABP0000001059789.237181.4714
ENSG00000128191homo_sapiensENSP0000026320981.241972.7038seriola_dumeriliENSSDUP0000000328780.409771.959
ENSG00000128191homo_sapiensENSP0000026320979.301470.3752cottoperca_gobioENSCGOP0000000186578.589769.7436
ENSG00000128191homo_sapiensENSP0000026320989.909483.6999struthio_camelus_australisENSSCUP0000000543589.677483.4839
ENSG00000128191homo_sapiensENSP0000026320990.297584.088anser_brachyrhynchusENSABRP0000001821390.064583.871
ENSG00000128191homo_sapiensENSP0000026320979.818971.022gasterosteus_aculeatusENSGACP0000001715182.157173.1025
ENSG00000128191homo_sapiensENSP0000026320978.007869.4696cynoglossus_semilaevisENSCSEP0000001800278.515669.9219
ENSG00000128191homo_sapiensENSP0000026320979.560269.9871poecilia_formosaENSPFOP0000001085478.544169.0932
ENSG00000128191homo_sapiensENSP0000026320981.371373.0919myripristis_murdjanENSMMDP0000504451080.537872.3431
ENSG00000128191homo_sapiensENSP0000026320979.818971.5395sander_luciopercaENSSLUP0000002650378.598770.4459
ENSG00000128191homo_sapiensENSP0000026320990.038883.5705strigops_habroptilaENSSHBP0000502142989.806483.3548
ENSG00000128191homo_sapiensENSP0000026320979.948271.5395amphiprion_ocellarisENSAOCP0000000586379.332570.9884
ENSG00000128191homo_sapiensENSP0000026320990.685683.8292terrapene_carolina_triunguisENSTMTP0000000820390.685683.8292
ENSG00000128191homo_sapiensENSP0000026320953.428245.7956hucho_huchoENSHHUP0000003879070.719260.6164
ENSG00000128191homo_sapiensENSP0000026320979.948271.1514hucho_huchoENSHHUP0000007607877.443668.9223
ENSG00000128191homo_sapiensENSP0000026320979.818971.2807betta_splendensENSBSLP0000003962678.598770.1911
ENSG00000128191homo_sapiensENSP0000026320980.983273.3506pygocentrus_nattereriENSPNAP0000003001280.051172.5064
ENSG00000128191homo_sapiensENSP0000026320980.595171.6688anabas_testudineusENSATEP0000002228779.769570.9347
ENSG00000128191homo_sapiensENSP0000026320924.450216.8176ciona_savignyiENSCSAVP0000000314859.062540.625
ENSG00000128191homo_sapiensENSP0000026320981.241972.7038seriola_lalandi_dorsalisENSSLDP0000002015580.409771.959
ENSG00000128191homo_sapiensENSP0000026320979.689571.1514labrus_bergyltaENSLBEP0000003342178.471370.0637
ENSG00000128191homo_sapiensENSP0000026320980.20771.1514pundamilia_nyerereiENSPNYP0000000580979.283970.3325
ENSG00000128191homo_sapiensENSP0000026320977.619769.599mastacembelus_armatusENSMAMP0000004234175.471767.673
ENSG00000128191homo_sapiensENSP0000026320980.336371.5395stegastes_partitusENSSPAP0000001277479.411870.7161
ENSG00000128191homo_sapiensENSP0000026320980.853871.6688oncorhynchus_tshawytschaENSOTSP0000507405078.419169.5107
ENSG00000128191homo_sapiensENSP0000026320978.137169.2109oncorhynchus_tshawytschaENSOTSP0000509992061.948754.8718
ENSG00000128191homo_sapiensENSP0000026320947.089340.2329acanthochromis_polyacanthusENSAPOP0000001325069.465759.3511
ENSG00000128191homo_sapiensENSP0000026320990.426984.3467aquila_chrysaetos_chrysaetosENSACCP0002000473890.193684.129
ENSG00000128191homo_sapiensENSP0000026320979.172170.8926nothobranchius_furzeriENSNFUP0001501224878.061269.898
ENSG00000128191homo_sapiensENSP0000026320978.913369.9871cyprinodon_variegatusENSCVAP0000000701678.913369.9871
ENSG00000128191homo_sapiensENSP0000026320982.018173.2212denticeps_clupeoidesENSDCDP0000003891381.074272.3785
ENSG00000128191homo_sapiensENSP0000026320979.948271.5395larimichthys_croceaENSLCRP0000504360277.931969.7352
ENSG00000128191homo_sapiensENSP0000026320979.818971.4101takifugu_rubripesENSTRUP0000003472479.204170.8601
ENSG00000128191homo_sapiensENSP0000026320990.168283.3118ficedula_albicollisENSFALP0000000849989.935583.0968
ENSG00000128191homo_sapiensENSP0000026320979.172169.9871hippocampus_comesENSHCOP0000001862178.361169.2702
ENSG00000128191homo_sapiensENSP0000026320979.948271.2807cyprinus_carpio_carpioENSCCRP0000001741079.434470.8226
ENSG00000128191homo_sapiensENSP0000026320980.20772.445cyprinus_carpio_carpioENSCCRP0000002329478.085670.529
ENSG00000128191homo_sapiensENSP0000026320990.297584.088coturnix_japonicaENSCJPP0000502425890.064583.871
ENSG00000128191homo_sapiensENSP0000026320979.430869.8577poecilia_latipinnaENSPLAP0000002012978.416368.9655
ENSG00000128191homo_sapiensENSP0000026320979.560271.2807sinocyclocheilus_grahamiENSSGRP0000008052178.544170.3704
ENSG00000128191homo_sapiensENSP0000026320959.767154.5925sinocyclocheilus_grahamiENSSGRP0000005682681.481574.4268
ENSG00000128191homo_sapiensENSP0000026320980.20771.1514maylandia_zebraENSMZEP0000502498579.283970.3325
ENSG00000128191homo_sapiensENSP0000026320979.818971.1514tetraodon_nigroviridisENSTNIP0000001987480.86572.0839
ENSG00000128191homo_sapiensENSP0000026320979.301472.0569paramormyrops_kingsleyaeENSPKIP0000002889679.19971.9638
ENSG00000128191homo_sapiensENSP0000026320980.336373.868scleropages_formosusENSSFOP0001502728179.717673.2991
ENSG00000128191homo_sapiensENSP0000026320983.441173.3506leptobrachium_leishanenseENSLLEP0000000833483.549273.4456
ENSG00000128191homo_sapiensENSP0000026320976.455468.1759scophthalmus_maximusENSSMAP0000003215574.339666.2893
ENSG00000128191homo_sapiensENSP0000026320978.78469.8577oryzias_melastigmaENSOMEP0000001744578.88669.9482

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003725enables double-stranded RNA binding2IBA,IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus1IDAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005730located_in nucleolus1IEAHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm1IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol1IDAHomo_sapiens(9606)Component
GO:0014069located_in postsynaptic density1IEAHomo_sapiens(9606)Component
GO:0016604located_in nuclear body1IDAHomo_sapiens(9606)Component
GO:0020037enables heme binding1IDAHomo_sapiens(9606)Function
GO:0031053involved_in primary miRNA processing3IBA,IDAHomo_sapiens(9606)Process
GO:0042802enables identical protein binding1IPIHomo_sapiens(9606)Function
GO:0042803enables protein homodimerization activity1IDAHomo_sapiens(9606)Function
GO:0046872enables metal ion binding1IEAHomo_sapiens(9606)Function
GO:0070877part_of microprocessor complex2IBA,IDAHomo_sapiens(9606)Component
GO:0070878enables primary miRNA binding2IBA,IDAHomo_sapiens(9606)Function
GO:0072091involved_in regulation of stem cell proliferation1IEAHomo_sapiens(9606)Process
GO:0098978located_in glutamatergic synapse1IEAHomo_sapiens(9606)Component
GO:0140517enables protein-RNA adaptor activity1IDAHomo_sapiens(9606)Function
GO:2000633involved_in positive regulation of pre-miRNA processing1IDAHomo_sapiens(9606)Process

Expression