RBP Type	Canonical_RBPs
Diseases	Cancer
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Transmemebrane
Localizations	N.A.
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000127804	Gene ID	79066	Accession	28484
Symbol	METTL16	Alias	METT10D	Full Name	methyltransferase 16, RNA N6-adenosine
Status	Confidence	Length	95841 bases	Strand	Minus strand
Position	17 : 2416049 - 2511889	RNA binding domain	MTS
Summary	Enables RNA binding activity and RNA methyltransferase activity. Involved in RNA modification and regulation of mRNA metabolic process. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000263092	MTS	PF05175	0.00014	1

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal
31940410	Characterization of METTL16 as a cytoplasmic RNA binding protein.	J Daniel Nance	2020-01-01	PloS one
34238292	Identification and validation of lncRNAs involved in m6A regulation for patients with ovarian cancer.	Jianfeng Zheng	2021-07-08	Cancer cell international
35935968	RNA m6A modification orchestrates the rhythm of immune cell development from hematopoietic stem cells to T and B cells.	Chuanxiang Zhao	2022-01-01	Frontiers in immunology
34227247	RNA methyltransferase METTL16: Targets and function.	R Emily Satterwhite	2022-03-01	Wiley interdisciplinary reviews. RNA
34780697	Human Mat2A Uses an Ordered Kinetic Mechanism and Is Stabilized but Not Regulated by Mat2B.	Jonathan Bailey	2021-11-30	Biochemistry
30575725	The H/ACA complex disrupts triplex in hTR precursor to permit processing by RRP6 and PARN.	Chi-Kang Tseng	2018-12-21	Nature communications
31036863	The interactome of a family of potential methyltransferases in HeLa cells.	V Valentina Ignatova	2019-04-29	Scientific reports
30197299	Methylation of Structured RNA by the m6A Writer METTL16 Is Essential for Mouse Embryonic Development.	Mateusz Mendel	2018-09-20	Molecular cell
34480573	Evolution of Methyltransferase-Like (METTL) Proteins in Metazoa: A Complex Gene Family Involved in Epitranscriptomic Regulation and Other Epigenetic Processes.	M Juliet Wong	2021-12-09	Molecular biology and evolution
37504262	RNA Methyltransferase METTL16's Protein Domains Have Differential Functional Effects on Cell Processes.	S Emily Talic	2023-06-29	Current issues in molecular biology
33949310	SAM homeostasis is regulated by CFIm-mediated splicing of MAT2A.	M Anna Scarborough	2021-05-05	eLife
33671635	METTL16, Methyltransferase-Like Protein 16: Current Insights into Structure and Function.	Agnieszka Ruszkowska	2021-02-22	International journal of molecular sciences

Name	Transcript ID	bp	Protein	Translation ID
METTL16-204	ENST00000571332	2644	No protein	-
METTL16-202	ENST00000381977	490	No protein	-
METTL16-206	ENST00000574623	759	No protein	-
METTL16-201	ENST00000263092	5740	562aa	ENSP00000263092
METTL16-205	ENST00000571669	5606	No protein	-
METTL16-208	ENST00000576556	1944	121aa	ENSP00000460775
METTL16-207	ENST00000574752	1602	168aa	ENSP00000460207
METTL16-203	ENST00000571298	624	101aa	ENSP00000465733
METTL16-209	ENST00000576976	575	148aa	ENSP00000461546
METTL16-210	ENST00000577148	554	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
44	Macular Degeneration	6.050132E-6	-
12697	Macular Degeneration	6.703E-6	-
16140	Stroke	2.3993062E-004	19369658
17205	Cholesterol, HDL	2.03e-005	19060910
17257	Cholesterol, HDL	3.061e-005	19060910
17271	Cholesterol, HDL	2.33e-007	19060910
17283	Cholesterol, HDL	8.354e-007	19060910
40387	Platelet Function Tests	1.8035500E-005	-
96139	Cholesterol, HDL	2E-7	19060910

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000127804

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000127804	homo_sapiens	ENSP00000263092	96.4413	95.9075	nomascus_leucogenys	ENSNLEP00000035383	92.0204	91.511
ENSG00000127804	homo_sapiens	ENSP00000263092	98.0427	97.331	pan_paniscus	ENSPPAP00000013543	93.5484	92.8693
ENSG00000127804	homo_sapiens	ENSP00000263092	98.5765	98.2206	pongo_abelii	ENSPPYP00000008782	98.5765	98.2206
ENSG00000127804	homo_sapiens	ENSP00000263092	98.0427	97.5089	pan_troglodytes	ENSPTRP00000067743	93.5484	93.039
ENSG00000127804	homo_sapiens	ENSP00000263092	97.6868	96.9751	gorilla_gorilla	ENSGGOP00000033200	93.8462	93.1624
ENSG00000127804	homo_sapiens	ENSP00000263092	86.2989	78.8256	ornithorhynchus_anatinus	ENSOANP00000013756	84.3478	77.0435
ENSG00000127804	homo_sapiens	ENSP00000263092	86.6548	81.6726	sarcophilus_harrisii	ENSSHAP00000014133	86.5009	81.5275
ENSG00000127804	homo_sapiens	ENSP00000263092	88.2562	82.0285	notamacropus_eugenii	ENSMEUP00000014519	89.3694	83.0631
ENSG00000127804	homo_sapiens	ENSP00000263092	61.032	57.1174	choloepus_hoffmanni	ENSCHOP00000010140	88.1748	82.5193
ENSG00000127804	homo_sapiens	ENSP00000263092	84.3416	80.7829	erinaceus_europaeus	ENSEEUP00000011168	84.3416	80.7829
ENSG00000127804	homo_sapiens	ENSP00000263092	76.3345	73.6655	echinops_telfairi	ENSETEP00000008665	82.9787	80.0774
ENSG00000127804	homo_sapiens	ENSP00000263092	93.4164	91.4591	callithrix_jacchus	ENSCJAP00000022671	95.6284	93.6248
ENSG00000127804	homo_sapiens	ENSP00000263092	97.5089	96.7971	cercocebus_atys	ENSCATP00000022411	97.5089	96.7971
ENSG00000127804	homo_sapiens	ENSP00000263092	96.7971	95.7295	macaca_fascicularis	ENSMFAP00000038785	89.769	88.7789
ENSG00000127804	homo_sapiens	ENSP00000263092	97.6868	96.9751	macaca_mulatta	ENSMMUP00000035426	97.861	97.1479
ENSG00000127804	homo_sapiens	ENSP00000263092	91.1032	90.0356	macaca_nemestrina	ENSMNEP00000020086	95.7009	94.5794
ENSG00000127804	homo_sapiens	ENSP00000263092	97.6868	97.153	papio_anubis	ENSPANP00000019502	97.6868	97.153
ENSG00000127804	homo_sapiens	ENSP00000263092	95.9075	94.6619	mandrillus_leucophaeus	ENSMLEP00000019866	91.511	90.3226
ENSG00000127804	homo_sapiens	ENSP00000263092	79.8932	78.8256	tursiops_truncatus	ENSTTRP00000001114	80.1786	79.1071
ENSG00000127804	homo_sapiens	ENSP00000263092	94.484	91.9929	vulpes_vulpes	ENSVVUP00000029963	94.6524	92.1569
ENSG00000127804	homo_sapiens	ENSP00000263092	91.637	87.5445	mus_spretus	MGP_SPRETEiJ_P0029573	86.8465	82.968
ENSG00000127804	homo_sapiens	ENSP00000263092	94.3061	91.637	equus_asinus	ENSEASP00005013131	94.4742	91.8004
ENSG00000127804	homo_sapiens	ENSP00000263092	81.8505	76.3345	capra_hircus	ENSCHIP00000000875	87.4525	81.5589
ENSG00000127804	homo_sapiens	ENSP00000263092	93.2384	90.3915	capra_hircus	ENSCHIP00000007057	94.4144	91.5315
ENSG00000127804	homo_sapiens	ENSP00000263092	80.2491	74.911	capra_hircus	ENSCHIP00000028567	88.0859	82.2266
ENSG00000127804	homo_sapiens	ENSP00000263092	93.2384	90.9253	loxodonta_africana	ENSLAFP00000006301	87.7722	85.5946
ENSG00000127804	homo_sapiens	ENSP00000263092	94.8399	91.8149	panthera_leo	ENSPLOP00000015751	95.0089	91.9786
ENSG00000127804	homo_sapiens	ENSP00000263092	95.9075	93.0605	ailuropoda_melanoleuca	ENSAMEP00000007935	95.9075	93.0605
ENSG00000127804	homo_sapiens	ENSP00000263092	93.9502	90.5694	bos_indicus_hybrid	ENSBIXP00005007101	94.1176	90.7308
ENSG00000127804	homo_sapiens	ENSP00000263092	93.0605	90.3915	oryctolagus_cuniculus	ENSOCUP00000019864	93.0605	90.3915
ENSG00000127804	homo_sapiens	ENSP00000263092	94.1281	91.4591	equus_caballus	ENSECAP00000031282	90.1192	87.5639
ENSG00000127804	homo_sapiens	ENSP00000263092	93.4164	91.1032	canis_lupus_familiaris	ENSCAFP00845020424	94.5946	92.2523
ENSG00000127804	homo_sapiens	ENSP00000263092	95.0178	91.9929	panthera_pardus	ENSPPRP00000029715	95.0178	91.9929
ENSG00000127804	homo_sapiens	ENSP00000263092	91.9929	88.6121	marmota_marmota_marmota	ENSMMMP00000027593	93.4901	90.0543
ENSG00000127804	homo_sapiens	ENSP00000263092	94.8399	91.8149	balaenoptera_musculus	ENSBMSP00010027669	95.0089	91.9786
ENSG00000127804	homo_sapiens	ENSP00000263092	92.5267	90.0356	cavia_porcellus	ENSCPOP00000022975	94.2029	91.6667
ENSG00000127804	homo_sapiens	ENSP00000263092	95.1957	91.9929	felis_catus	ENSFCAP00000005869	95.1957	91.9929
ENSG00000127804	homo_sapiens	ENSP00000263092	56.7616	54.4484	ursus_americanus	ENSUAMP00000033043	93.0029	89.2128
ENSG00000127804	homo_sapiens	ENSP00000263092	33.274	32.0285	monodelphis_domestica	ENSMODP00000044920	89.4737	86.1244
ENSG00000127804	homo_sapiens	ENSP00000263092	34.6975	33.8078	monodelphis_domestica	ENSMODP00000013490	94.2029	91.7874
ENSG00000127804	homo_sapiens	ENSP00000263092	94.484	91.1032	bison_bison_bison	ENSBBBP00000014983	94.3162	90.9414
ENSG00000127804	homo_sapiens	ENSP00000263092	95.0178	91.637	monodon_monoceros	ENSMMNP00015027185	95.1872	91.8004
ENSG00000127804	homo_sapiens	ENSP00000263092	94.1281	91.1032	sus_scrofa	ENSSSCP00000040541	94.2959	91.2656
ENSG00000127804	homo_sapiens	ENSP00000263092	95.7295	94.3061	microcebus_murinus	ENSMICP00000011861	96.4158	94.9821
ENSG00000127804	homo_sapiens	ENSP00000263092	70.2847	66.548	octodon_degus	ENSODEP00000006212	88.3669	83.6689
ENSG00000127804	homo_sapiens	ENSP00000263092	38.4342	36.4769	octodon_degus	ENSODEP00000013713	89.2562	84.7107
ENSG00000127804	homo_sapiens	ENSP00000263092	93.2384	90.9253	octodon_degus	ENSODEP00000010140	94.7559	92.4051
ENSG00000127804	homo_sapiens	ENSP00000263092	83.274	79.8932	jaculus_jaculus	ENSJJAP00000014117	93.0417	89.2644
ENSG00000127804	homo_sapiens	ENSP00000263092	76.1566	72.4199	jaculus_jaculus	ENSJJAP00000005517	88.9813	84.6154
ENSG00000127804	homo_sapiens	ENSP00000263092	23.6655	21.8861	ovis_aries_rambouillet	ENSOARP00020021937	80.6061	74.5455
ENSG00000127804	homo_sapiens	ENSP00000263092	95.0178	91.8149	ovis_aries_rambouillet	ENSOARP00020028074	94.849	91.6519
ENSG00000127804	homo_sapiens	ENSP00000263092	95.3737	92.1708	ursus_maritimus	ENSUMAP00000012442	95.5437	92.3351
ENSG00000127804	homo_sapiens	ENSP00000263092	73.3096	70.6406	ochotona_princeps	ENSOPRP00000002015	80.7843	77.8431
ENSG00000127804	homo_sapiens	ENSP00000263092	95.0178	91.4591	delphinapterus_leucas	ENSDLEP00000017519	95.1872	91.6221
ENSG00000127804	homo_sapiens	ENSP00000263092	35.0534	34.5196	physeter_catodon	ENSPCTP00005008446	98.0099	96.5174
ENSG00000127804	homo_sapiens	ENSP00000263092	91.8149	88.0783	mus_caroli	MGP_CAROLIEiJ_P0028183	93.3092	89.5118
ENSG00000127804	homo_sapiens	ENSP00000263092	91.8149	87.7224	mus_musculus	ENSMUSP00000010698	87.0152	83.1366
ENSG00000127804	homo_sapiens	ENSP00000263092	37.7224	35.7651	dipodomys_ordii	ENSDORP00000017311	93.8053	88.938
ENSG00000127804	homo_sapiens	ENSP00000263092	94.8399	92.1708	mustela_putorius_furo	ENSMPUP00000012763	94.8399	92.1708
ENSG00000127804	homo_sapiens	ENSP00000263092	95.0178	93.7722	aotus_nancymaae	ENSANAP00000030087	96.0432	94.7842
ENSG00000127804	homo_sapiens	ENSP00000263092	27.5801	27.4021	saimiri_boliviensis_boliviensis	ENSSBOP00000019280	99.359	98.7179
ENSG00000127804	homo_sapiens	ENSP00000263092	87.3665	85.7651	saimiri_boliviensis_boliviensis	ENSSBOP00000012415	95.7115	93.9571
ENSG00000127804	homo_sapiens	ENSP00000263092	95.3737	91.9929	vicugna_pacos	ENSVPAP00000000211	95.5437	92.1569
ENSG00000127804	homo_sapiens	ENSP00000263092	97.5089	96.9751	chlorocebus_sabaeus	ENSCSAP00000009914	97.5089	96.9751
ENSG00000127804	homo_sapiens	ENSP00000263092	58.7189	57.2954	tupaia_belangeri	ENSTBEP00000004614	65.4762	63.8889
ENSG00000127804	homo_sapiens	ENSP00000263092	84.3416	79.7153	mesocricetus_auratus	ENSMAUP00000015581	91.3295	86.3198
ENSG00000127804	homo_sapiens	ENSP00000263092	87.5445	83.6299	phocoena_sinus	ENSPSNP00000027857	88.0143	84.0787
ENSG00000127804	homo_sapiens	ENSP00000263092	94.8399	91.637	camelus_dromedarius	ENSCDRP00005011644	95.3488	92.1288
ENSG00000127804	homo_sapiens	ENSP00000263092	95.0178	93.0605	carlito_syrichta	ENSTSYP00000005733	96.0432	94.0648
ENSG00000127804	homo_sapiens	ENSP00000263092	95.0178	91.9929	panthera_tigris_altaica	ENSPTIP00000013989	95.0178	91.9929
ENSG00000127804	homo_sapiens	ENSP00000263092	91.2811	87.3665	rattus_norvegicus	ENSRNOP00000079437	92.7667	88.7884
ENSG00000127804	homo_sapiens	ENSP00000263092	96.2633	94.8399	prolemur_simus	ENSPSMP00000012711	93.9236	92.5347
ENSG00000127804	homo_sapiens	ENSP00000263092	28.1139	27.9359	microtus_ochrogaster	ENSMOCP00000002402	98.75	98.125
ENSG00000127804	homo_sapiens	ENSP00000263092	91.2811	87.5445	peromyscus_maniculatus_bairdii	ENSPEMP00000023970	92.7667	88.9693
ENSG00000127804	homo_sapiens	ENSP00000263092	28.8256	24.5552	bos_mutus	ENSBMUP00000024585	67.7824	57.7406
ENSG00000127804	homo_sapiens	ENSP00000263092	19.7509	19.395	bos_mutus	ENSBMUP00000028528	99.1071	97.3214
ENSG00000127804	homo_sapiens	ENSP00000263092	91.637	87.5445	mus_spicilegus	ENSMSIP00000027659	86.8465	82.968
ENSG00000127804	homo_sapiens	ENSP00000263092	91.1032	87.3665	cricetulus_griseus_chok1gshd	ENSCGRP00001006076	92.5859	88.7884
ENSG00000127804	homo_sapiens	ENSP00000263092	63.7011	62.2776	pteropus_vampyrus	ENSPVAP00000002049	64.3885	62.9496
ENSG00000127804	homo_sapiens	ENSP00000263092	93.7722	90.7473	myotis_lucifugus	ENSMLUP00000003219	93.4397	90.4255
ENSG00000127804	homo_sapiens	ENSP00000263092	87.3665	81.8505	vombatus_ursinus	ENSVURP00010009965	88.4685	82.8829
ENSG00000127804	homo_sapiens	ENSP00000263092	95.1957	92.5267	rhinolophus_ferrumequinum	ENSRFEP00010010151	95.3654	92.6916
ENSG00000127804	homo_sapiens	ENSP00000263092	90.5694	86.4769	neovison_vison	ENSNVIP00000016068	90.5694	86.4769
ENSG00000127804	homo_sapiens	ENSP00000263092	29.3594	27.5801	bos_taurus	ENSBTAP00000072860	77.4648	72.77
ENSG00000127804	homo_sapiens	ENSP00000263092	93.9502	90.5694	bos_taurus	ENSBTAP00000035031	82.1151	79.1602
ENSG00000127804	homo_sapiens	ENSP00000263092	38.2562	35.7651	heterocephalus_glaber_female	ENSHGLP00000059650	93.4783	87.3913
ENSG00000127804	homo_sapiens	ENSP00000263092	95.0178	93.7722	rhinopithecus_bieti	ENSRBIP00000000658	90.6621	89.4737
ENSG00000127804	homo_sapiens	ENSP00000263092	94.484	92.1708	canis_lupus_dingo	ENSCAFP00020012057	94.6524	92.3351
ENSG00000127804	homo_sapiens	ENSP00000263092	93.2384	89.5018	sciurus_vulgaris	ENSSVLP00005028316	91.1304	87.4783
ENSG00000127804	homo_sapiens	ENSP00000263092	86.6548	81.3167	phascolarctos_cinereus	ENSPCIP00000020858	87.7477	82.3423
ENSG00000127804	homo_sapiens	ENSP00000263092	94.3061	91.1032	procavia_capensis	ENSPCAP00000012431	94.3061	91.1032
ENSG00000127804	homo_sapiens	ENSP00000263092	36.2989	35.0534	nannospalax_galili	ENSNGAP00000011772	95.7747	92.4883
ENSG00000127804	homo_sapiens	ENSP00000263092	94.484	91.1032	bos_grunniens	ENSBGRP00000037308	94.3162	90.9414
ENSG00000127804	homo_sapiens	ENSP00000263092	94.484	91.9929	chinchilla_lanigera	ENSCLAP00000011985	94.6524	92.1569
ENSG00000127804	homo_sapiens	ENSP00000263092	94.1281	90.5694	cervus_hanglu_yarkandensis	ENSCHYP00000021698	92	88.5217
ENSG00000127804	homo_sapiens	ENSP00000263092	35.0534	34.8754	catagonus_wagneri	ENSCWAP00000001244	98.0099	97.5124
ENSG00000127804	homo_sapiens	ENSP00000263092	51.2456	47.6868	catagonus_wagneri	ENSCWAP00000001260	91.7197	85.3503
ENSG00000127804	homo_sapiens	ENSP00000263092	92.1708	88.6121	ictidomys_tridecemlineatus	ENSSTOP00000010651	93.6709	90.0543
ENSG00000127804	homo_sapiens	ENSP00000263092	94.3061	93.0605	otolemur_garnettii	ENSOGAP00000004023	94.4742	93.2264
ENSG00000127804	homo_sapiens	ENSP00000263092	94.6619	93.4164	cebus_imitator	ENSCCAP00000020595	96.0289	94.7653
ENSG00000127804	homo_sapiens	ENSP00000263092	43.2384	39.5018	urocitellus_parryii	ENSUPAP00010022255	82.9352	75.7679
ENSG00000127804	homo_sapiens	ENSP00000263092	34.8754	33.9858	urocitellus_parryii	ENSUPAP00010022252	97.5124	95.0249
ENSG00000127804	homo_sapiens	ENSP00000263092	91.1032	88.0783	moschus_moschiferus	ENSMMSP00000009351	86.6328	83.7563
ENSG00000127804	homo_sapiens	ENSP00000263092	95.1957	93.9502	rhinopithecus_roxellana	ENSRROP00000027241	90.8319	89.6435
ENSG00000127804	homo_sapiens	ENSP00000263092	91.8149	88.0783	mus_pahari	MGP_PahariEiJ_P0034923	86.8687	83.3333
ENSG00000127804	homo_sapiens	ENSP00000263092	96.6192	94.8399	propithecus_coquereli	ENSPCOP00000029950	96.4476	94.6714
ENSG00000127804	homo_sapiens	ENSP00000263092	40.2135	26.8683	caenorhabditis_elegans	ZK1128.2a.1	47.1816	31.524
ENSG00000127804	homo_sapiens	ENSP00000263092	33.0961	22.7758	drosophila_melanogaster	FBpp0289552	60.9836	41.9672
ENSG00000127804	homo_sapiens	ENSP00000263092	20.9964	16.3701	petromyzon_marinus	ENSPMAP00000004516	62.4339	48.6772
ENSG00000127804	homo_sapiens	ENSP00000263092	63.879	50.8897	eptatretus_burgeri	ENSEBUP00000004346	67.7358	53.9623
ENSG00000127804	homo_sapiens	ENSP00000263092	77.0463	70.1068	callorhinchus_milii	ENSCMIP00000025516	70.6362	64.2741
ENSG00000127804	homo_sapiens	ENSP00000263092	79.8932	72.4199	latimeria_chalumnae	ENSLACP00000020657	75.8446	68.75
ENSG00000127804	homo_sapiens	ENSP00000263092	75.8007	67.7936	lepisosteus_oculatus	ENSLOCP00000005293	75.1323	67.1958
ENSG00000127804	homo_sapiens	ENSP00000263092	73.6655	63.5231	clupea_harengus	ENSCHAP00000008959	72.7592	62.7417
ENSG00000127804	homo_sapiens	ENSP00000263092	70.2847	61.9217	danio_rerio	ENSDARP00000072692	83.8641	73.8854
ENSG00000127804	homo_sapiens	ENSP00000263092	21.5302	18.8612	carassius_auratus	ENSCARP00000043248	78.5714	68.8312
ENSG00000127804	homo_sapiens	ENSP00000263092	73.8434	64.2349	carassius_auratus	ENSCARP00000006876	80.2708	69.8259
ENSG00000127804	homo_sapiens	ENSP00000263092	70.2847	60.4982	astyanax_mexicanus	ENSAMXP00000047070	53.3063	45.8839
ENSG00000127804	homo_sapiens	ENSP00000263092	72.4199	62.0996	ictalurus_punctatus	ENSIPUP00000007981	80.4348	68.9723
ENSG00000127804	homo_sapiens	ENSP00000263092	75.9786	64.0569	esox_lucius	ENSELUP00000007107	70.8126	59.7015
ENSG00000127804	homo_sapiens	ENSP00000263092	73.3096	63.3452	electrophorus_electricus	ENSEEEP00000052654	72.9204	63.0089
ENSG00000127804	homo_sapiens	ENSP00000263092	43.9502	35.9431	oncorhynchus_kisutch	ENSOKIP00005046457	68.232	55.8011
ENSG00000127804	homo_sapiens	ENSP00000263092	76.1566	64.5907	oncorhynchus_kisutch	ENSOKIP00005017169	73.5395	62.3711
ENSG00000127804	homo_sapiens	ENSP00000263092	75.9786	64.9466	oncorhynchus_mykiss	ENSOMYP00000060724	70.2303	60.0329
ENSG00000127804	homo_sapiens	ENSP00000263092	56.4057	46.4413	oncorhynchus_mykiss	ENSOMYP00000068827	75.6563	62.2912
ENSG00000127804	homo_sapiens	ENSP00000263092	76.5125	64.5907	salmo_salar	ENSSSAP00000102028	71.7863	60.601
ENSG00000127804	homo_sapiens	ENSP00000263092	59.2527	50.3559	salmo_salar	ENSSSAP00000087416	76.5517	65.0575
ENSG00000127804	homo_sapiens	ENSP00000263092	74.911	64.0569	salmo_trutta	ENSSTUP00000112380	70.8754	60.6061
ENSG00000127804	homo_sapiens	ENSP00000263092	56.5836	47.331	salmo_trutta	ENSSTUP00000100781	66.6667	55.7652
ENSG00000127804	homo_sapiens	ENSP00000263092	73.8434	61.9217	gadus_morhua	ENSGMOP00000043897	72.0486	60.4167
ENSG00000127804	homo_sapiens	ENSP00000263092	73.6655	62.4555	poecilia_reticulata	ENSPREP00000032502	75.2727	63.8182
ENSG00000127804	homo_sapiens	ENSP00000263092	74.5552	63.5231	xiphophorus_maculatus	ENSXMAP00000008642	76.0436	64.7913
ENSG00000127804	homo_sapiens	ENSP00000263092	74.0214	63.1673	oryzias_latipes	ENSORLP00000009902	72.9825	62.2807
ENSG00000127804	homo_sapiens	ENSP00000263092	74.0214	63.1673	cyclopterus_lumpus	ENSCLMP00005023389	73.1107	62.3902
ENSG00000127804	homo_sapiens	ENSP00000263092	74.7331	63.5231	oreochromis_niloticus	ENSONIP00000064106	71.1864	60.5085
ENSG00000127804	homo_sapiens	ENSP00000263092	75.2669	63.879	haplochromis_burtoni	ENSHBUP00000031044	76.0791	64.5683
ENSG00000127804	homo_sapiens	ENSP00000263092	75.089	63.7011	astatotilapia_calliptera	ENSACLP00000030418	74.4268	63.1393
ENSG00000127804	homo_sapiens	ENSP00000263092	75.089	64.0569	sparus_aurata	ENSSAUP00010044472	76.1733	64.9819
ENSG00000127804	homo_sapiens	ENSP00000263092	70.6406	62.0996	lates_calcarifer	ENSLCAP00010024646	87.8319	77.2124
ENSG00000127804	homo_sapiens	ENSP00000263092	78.1139	69.7509	xenopus_tropicalis	ENSXETP00000042103	79.9636	71.4025
ENSG00000127804	homo_sapiens	ENSP00000263092	85.0534	76.8683	chrysemys_picta_bellii	ENSCPBP00000002244	85.5098	77.2809
ENSG00000127804	homo_sapiens	ENSP00000263092	76.6904	69.395	sphenodon_punctatus	ENSSPUP00000006263	81.015	73.3083
ENSG00000127804	homo_sapiens	ENSP00000263092	78.1139	68.8612	crocodylus_porosus	ENSCPRP00005002187	63.9942	56.414
ENSG00000127804	homo_sapiens	ENSP00000263092	80.605	70.4626	laticauda_laticaudata	ENSLLTP00000007019	82.0652	71.7391
ENSG00000127804	homo_sapiens	ENSP00000263092	79.3594	69.9288	notechis_scutatus	ENSNSUP00000013775	80.0718	70.5566
ENSG00000127804	homo_sapiens	ENSP00000263092	79.7153	69.9288	pseudonaja_textilis	ENSPTXP00000013060	80.5755	70.6835
ENSG00000127804	homo_sapiens	ENSP00000263092	84.1637	75.6228	anas_platyrhynchos_platyrhynchos	ENSAPLP00000022581	84.6154	76.0286
ENSG00000127804	homo_sapiens	ENSP00000263092	83.6299	75.4448	gallus_gallus	ENSGALP00010037461	81.8815	73.8676
ENSG00000127804	homo_sapiens	ENSP00000263092	19.7509	18.1495	meleagris_gallopavo	ENSMGAP00000031554	94.0678	86.4407
ENSG00000127804	homo_sapiens	ENSP00000263092	68.1495	59.4306	meleagris_gallopavo	ENSMGAP00000020132	75.098	65.4902
ENSG00000127804	homo_sapiens	ENSP00000263092	83.9858	74.7331	serinus_canaria	ENSSCAP00000014766	84.4365	75.1342
ENSG00000127804	homo_sapiens	ENSP00000263092	84.1637	74.7331	parus_major	ENSPMJP00000013714	84.9192	75.4039
ENSG00000127804	homo_sapiens	ENSP00000263092	80.2491	69.9288	anolis_carolinensis	ENSACAP00000016637	80.6798	70.3041
ENSG00000127804	homo_sapiens	ENSP00000263092	62.0996	53.7367	neolamprologus_brichardi	ENSNBRP00000011199	80.0459	69.2661
ENSG00000127804	homo_sapiens	ENSP00000263092	79.5374	69.395	naja_naja	ENSNNAP00000017040	79.9642	69.7674
ENSG00000127804	homo_sapiens	ENSP00000263092	80.9609	71.5303	podarcis_muralis	ENSPMRP00000017436	62.4143	55.144
ENSG00000127804	homo_sapiens	ENSP00000263092	74.7331	66.3701	geospiza_fortis	ENSGFOP00000000555	83.8323	74.4511
ENSG00000127804	homo_sapiens	ENSP00000263092	83.9858	74.911	taeniopygia_guttata	ENSTGUP00000013764	84.4365	75.3131
ENSG00000127804	homo_sapiens	ENSP00000263092	72.7758	61.032	erpetoichthys_calabaricus	ENSECRP00000017063	78.2027	65.5832
ENSG00000127804	homo_sapiens	ENSP00000263092	74.0214	63.3452	kryptolebias_marmoratus	ENSKMAP00000021295	74.8201	64.0288
ENSG00000127804	homo_sapiens	ENSP00000263092	80.9609	70.9964	salvator_merianae	ENSSMRP00000009081	81.8345	71.7626
ENSG00000127804	homo_sapiens	ENSP00000263092	73.4875	62.4555	oryzias_javanicus	ENSOJAP00000017218	73.357	62.3446
ENSG00000127804	homo_sapiens	ENSP00000263092	73.4875	63.5231	amphilophus_citrinellus	ENSACIP00000003481	74.2806	64.2086
ENSG00000127804	homo_sapiens	ENSP00000263092	73.4875	63.1673	dicentrarchus_labrax	ENSDLAP00005015558	70.3577	60.477
ENSG00000127804	homo_sapiens	ENSP00000263092	73.6655	62.9893	amphiprion_percula	ENSAPEP00000019615	69.697	59.596
ENSG00000127804	homo_sapiens	ENSP00000263092	74.0214	63.879	oryzias_sinensis	ENSOSIP00000029022	74.8201	64.5683
ENSG00000127804	homo_sapiens	ENSP00000263092	77.758	70.6406	pelodiscus_sinensis	ENSPSIP00000016562	84.3629	76.6409
ENSG00000127804	homo_sapiens	ENSP00000263092	25.9786	23.8434	gopherus_evgoodei	ENSGEVP00005002815	94.8052	87.013
ENSG00000127804	homo_sapiens	ENSP00000263092	57.4733	50.1779	gopherus_evgoodei	ENSGEVP00005002796	82.1883	71.7557
ENSG00000127804	homo_sapiens	ENSP00000263092	85.5872	76.5125	chelonoidis_abingdonii	ENSCABP00000024528	86.0465	76.9231
ENSG00000127804	homo_sapiens	ENSP00000263092	75.4448	65.1246	seriola_dumerili	ENSSDUP00000021039	75.3108	65.0089
ENSG00000127804	homo_sapiens	ENSP00000263092	73.4875	63.1673	cottoperca_gobio	ENSCGOP00000021875	71.8261	61.7391
ENSG00000127804	homo_sapiens	ENSP00000263092	79.8932	71.1744	struthio_camelus_australis	ENSSCUP00000006460	82.6888	73.6648
ENSG00000127804	homo_sapiens	ENSP00000263092	84.1637	75.9786	anser_brachyrhynchus	ENSABRP00000016571	84.6154	76.3864
ENSG00000127804	homo_sapiens	ENSP00000263092	73.4875	62.6335	gasterosteus_aculeatus	ENSGACP00000011111	74.5487	63.5379
ENSG00000127804	homo_sapiens	ENSP00000263092	73.6655	61.9217	cynoglossus_semilaevis	ENSCSEP00000027766	75.5474	63.5037
ENSG00000127804	homo_sapiens	ENSP00000263092	74.0214	63.3452	poecilia_formosa	ENSPFOP00000015182	75.4991	64.6098
ENSG00000127804	homo_sapiens	ENSP00000263092	74.5552	63.5231	myripristis_murdjan	ENSMMDP00005008612	71.9931	61.3402
ENSG00000127804	homo_sapiens	ENSP00000263092	73.1317	63.7011	sander_lucioperca	ENSSLUP00000030309	70.3767	61.3014
ENSG00000127804	homo_sapiens	ENSP00000263092	83.8078	75.4448	strigops_habroptila	ENSSHBP00005009540	84.2576	75.8497
ENSG00000127804	homo_sapiens	ENSP00000263092	73.6655	62.9893	amphiprion_ocellaris	ENSAOCP00000004829	75.4098	64.4809
ENSG00000127804	homo_sapiens	ENSP00000263092	85.4093	76.5125	terrapene_carolina_triunguis	ENSTMTP00000023852	86.4865	77.4775
ENSG00000127804	homo_sapiens	ENSP00000263092	75.6228	64.2349	hucho_hucho	ENSHHUP00000068293	73.1497	62.1343
ENSG00000127804	homo_sapiens	ENSP00000263092	73.6655	63.3452	hucho_hucho	ENSHHUP00000059147	68.543	58.9404
ENSG00000127804	homo_sapiens	ENSP00000263092	74.3772	64.0569	betta_splendens	ENSBSLP00000016946	78.7194	67.7966
ENSG00000127804	homo_sapiens	ENSP00000263092	72.242	62.8114	pygocentrus_nattereri	ENSPNAP00000002726	76.6038	66.6038
ENSG00000127804	homo_sapiens	ENSP00000263092	71.8861	62.9893	anabas_testudineus	ENSATEP00000014999	74.2647	65.0735
ENSG00000127804	homo_sapiens	ENSP00000263092	75.6228	65.1246	seriola_lalandi_dorsalis	ENSSLDP00000027172	75.4885	65.0089
ENSG00000127804	homo_sapiens	ENSP00000263092	73.1317	63.5231	labrus_bergylta	ENSLBEP00000035611	75.2747	65.3846
ENSG00000127804	homo_sapiens	ENSP00000263092	67.7936	57.6512	pundamilia_nyererei	ENSPNYP00000022076	73.1286	62.1881
ENSG00000127804	homo_sapiens	ENSP00000263092	74.5552	63.879	mastacembelus_armatus	ENSMAMP00000043799	72.2414	61.8966
ENSG00000127804	homo_sapiens	ENSP00000263092	74.5552	64.9466	stegastes_partitus	ENSSPAP00000014377	75.3597	65.6475
ENSG00000127804	homo_sapiens	ENSP00000263092	11.9217	7.29537	oncorhynchus_tshawytscha	ENSOTSP00005039590	50	30.597
ENSG00000127804	homo_sapiens	ENSP00000263092	17.2598	14.9466	acanthochromis_polyacanthus	ENSAPOP00000027446	88.1818	76.3636
ENSG00000127804	homo_sapiens	ENSP00000263092	79.8932	70.2847	aquila_chrysaetos_chrysaetos	ENSACCP00020023791	78.087	68.6957
ENSG00000127804	homo_sapiens	ENSP00000263092	74.5552	63.5231	nothobranchius_furzeri	ENSNFUP00015000712	72.7431	61.9792
ENSG00000127804	homo_sapiens	ENSP00000263092	72.9537	62.6335	cyprinodon_variegatus	ENSCVAP00000011083	77.0677	66.1654
ENSG00000127804	homo_sapiens	ENSP00000263092	38.2562	32.2064	cyprinodon_variegatus	ENSCVAP00000018456	75.7042	63.7324
ENSG00000127804	homo_sapiens	ENSP00000263092	72.5979	63.7011	denticeps_clupeoides	ENSDCDP00000055190	76.6917	67.2932
ENSG00000127804	homo_sapiens	ENSP00000263092	69.573	62.6335	denticeps_clupeoides	ENSDCDP00000055250	83.547	75.2137
ENSG00000127804	homo_sapiens	ENSP00000263092	75.089	64.9466	larimichthys_crocea	ENSLCRP00005004244	72.1367	62.3932
ENSG00000127804	homo_sapiens	ENSP00000263092	74.5552	63.1673	takifugu_rubripes	ENSTRUP00000040404	74.9553	63.5063
ENSG00000127804	homo_sapiens	ENSP00000263092	83.452	74.911	ficedula_albicollis	ENSFALP00000005473	84.0502	75.448
ENSG00000127804	homo_sapiens	ENSP00000263092	75.8007	62.8114	hippocampus_comes	ENSHCOP00000013463	77.8793	64.5338
ENSG00000127804	homo_sapiens	ENSP00000263092	73.4875	63.7011	cyprinus_carpio_carpio	ENSCCRP00000067686	76.4815	66.2963
ENSG00000127804	homo_sapiens	ENSP00000263092	72.7758	62.8114	cyprinus_carpio_carpio	ENSCCRP00000104767	76.306	65.8582
ENSG00000127804	homo_sapiens	ENSP00000263092	82.2064	74.0214	coturnix_japonica	ENSCJPP00005021629	82.7957	74.552
ENSG00000127804	homo_sapiens	ENSP00000263092	74.1993	63.5231	poecilia_latipinna	ENSPLAP00000000885	75.6806	64.7913
ENSG00000127804	homo_sapiens	ENSP00000263092	66.3701	57.8292	sinocyclocheilus_grahami	ENSSGRP00000104707	82.34	71.7439
ENSG00000127804	homo_sapiens	ENSP00000263092	51.0676	46.0854	sinocyclocheilus_grahami	ENSSGRP00000085366	40.8832	36.8946
ENSG00000127804	homo_sapiens	ENSP00000263092	75.089	63.7011	maylandia_zebra	ENSMZEP00005020282	75.8993	64.3885
ENSG00000127804	homo_sapiens	ENSP00000263092	74.3772	62.9893	tetraodon_nigroviridis	ENSTNIP00000021129	78.5714	66.5414
ENSG00000127804	homo_sapiens	ENSP00000263092	74.0214	64.0569	paramormyrops_kingsleyae	ENSPKIP00000011498	75.7741	65.5738
ENSG00000127804	homo_sapiens	ENSP00000263092	71.1744	63.3452	scleropages_formosus	ENSSFOP00015039173	72.5953	64.6098
ENSG00000127804	homo_sapiens	ENSP00000263092	76.3345	65.8363	leptobrachium_leishanense	ENSLLEP00000004698	77.0197	66.4273
ENSG00000127804	homo_sapiens	ENSP00000263092	74.3772	62.4555	scophthalmus_maximus	ENSSMAP00000067961	73.4622	61.6872
ENSG00000127804	homo_sapiens	ENSP00000263092	72.9537	61.5658	oryzias_melastigma	ENSOMEP00000014973	75.3676	63.6029

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0001734	enables mRNA (N6-adenosine)-methyltransferase activity	1	IDA	Homo_sapiens(9606)	Function
GO:0003723	enables RNA binding	2	HDA,IDA	Homo_sapiens(9606)	Function
GO:0005634	is_active_in nucleus	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0005737	located_in cytoplasm	1	IDA	Homo_sapiens(9606)	Component
GO:0006402	involved_in mRNA catabolic process	1	ISS	Homo_sapiens(9606)	Process
GO:0006556	acts_upstream_of S-adenosylmethionine biosynthetic process	2	IDA,IMP	Homo_sapiens(9606)	Process
GO:0010608	involved_in post-transcriptional regulation of gene expression	1	IDA	Homo_sapiens(9606)	Process
GO:0030629	enables U6 snRNA 3-end binding	1	IDA	Homo_sapiens(9606)	Function
GO:0035613	enables RNA stem-loop binding	1	IDA	Homo_sapiens(9606)	Function
GO:0048024	involved_in regulation of mRNA splicing, via spliceosome	1	IDA	Homo_sapiens(9606)	Process
GO:0052907	enables 23S rRNA (adenine(1618)-N(6))-methyltransferase activity	1	IBA	Homo_sapiens(9606)	Function
GO:0061157	involved_in mRNA destabilization	1	ISS	Homo_sapiens(9606)	Process
GO:0070475	involved_in rRNA base methylation	1	IBA	Homo_sapiens(9606)	Process
GO:0080009	involved_in mRNA methylation	1	IDA	Homo_sapiens(9606)	Process
GO:0120048	enables U6 snRNA (adenine-(43)-N(6))-methyltransferase activity	1	IDA	Homo_sapiens(9606)	Function
GO:0120049	involved_in snRNA (adenine-N6)-methylation	1	IDA	Homo_sapiens(9606)	Process
GO:1905869	involved_in negative regulation of 3-UTR-mediated mRNA stabilization	1	IDA	Homo_sapiens(9606)	Process