Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases Cancer Disease
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions Transmemebrane
Localizations Stress granucle
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000127603 Gene ID 23499 Accession 13664
Symbol MACF1 Alias ACF7;LIS9;MACF;OFC4;ABP620;KIAA0754;Lnc-PMIF Full Name microtubule actin crosslinking factor 1
Status Confidence Length 405862 bases Strand Plus strand
Position 1 : 39081316 - 39487177 RNA binding domain N.A.
Summary This gene encodes a large protein containing numerous spectrin and leucine-rich repeat (LRR) domains. The encoded protein is a member of a family of proteins that form bridges between different cytoskeletal elements. This protein facilitates actin-microtubule interactions at the cell periphery and couples the microtubule network to cellular junctions. Alternative splicing results in multiple transcript variants, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, May 2013]

RNA binding proteomes (RBPomes)

Transcripts

Phenotypes

GWAS

Protein-Protein Interaction (PPI)

Paralogs

Orthologs

Gene Ontology

Expression