RBP Type	Canonical_RBPs
Diseases	CancerFlavivirusesHIVRVSARS-COV-2SINVDengueZika
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	N.A.
Localizations	Stress granucle
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000126457	Gene ID	3276	Accession	5187
Symbol	PRMT1	Alias	ANM1;HCP1;IR1B4;HRMT1L2	Full Name	protein arginine methyltransferase 1
Status	Confidence	Length	12665 bases	Strand	Plus strand
Position	19 : 49675786 - 49688450	RNA binding domain	Met_10 , MTS
Summary	This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2011]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000432349	Met_10	PF02475	0.00069	1
ENSP00000432349	MTS	PF05175	4.4e-05	2
ENSP00000432788	Met_10	PF02475	0.00069	1
ENSP00000432788	MTS	PF05175	4.4e-05	2
ENSP00000432538	MTS	PF05175	7.5e-05	1
ENSP00000431957	MTS	PF05175	7.6e-05	1
ENSP00000433480	MTS	PF05175	0.0001	1
ENSP00000484505	MTS	PF05175	0.00013	1
ENSP00000433556	MTS	PF05175	0.00017	1
ENSP00000375724	MTS	PF05175	0.00019	1
ENSP00000406162	MTS	PF05175	0.00021	1

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal
22309152	PRMT1 methylates the single Argonaute of Toxoplasma gondii and is important for the recruitment of Tudor nuclease for target RNA cleavage by antisense guide RNA.	Alla Musiyenko	2012-06-01	Cellular microbiology
33138308	The Regulatory Properties of the Ccr4-Not Complex.	Nafiseh N Chalabi	2020-10-29	Cells
36144454	Competing Endogenous RNA (ceRNA) Networks and Splicing Switches in Cervical Cancer: HPV Oncogenesis, Clinical Significance and Therapeutic Opportunities.	Afra Basera	2022-09-16	Microorganisms
26020839	Arginine methylation of hnRNPUL1 regulates interaction with NBS1 and recruitment to sites of DNA damage.	Gayathri Gurunathan	2015-05-28	Scientific reports
32365184	PRMT7 regulates RNA-binding capacity and protein stability in Leishmania parasites.	R Tiago Ferreira	2020-06-04	Nucleic acids research
37342192	Targeting pre-mRNA splicing in cancers: roles, inhibitors, and therapeutic opportunities.	Shinsuke Araki	2023-01-01	Frontiers in oncology
36358861	Protein Arginine Methyltransferases as Therapeutic Targets in Hematological Malignancies.	Camille Sauter	2022-11-05	Cancers
37138766	Reduced C9orf72 expression exacerbates polyGR toxicity in patient iPSC-derived motor neurons and a Type I protein arginine methyltransferase inhibitor reduces that toxicity.	L Therese Dane	2023-01-01	Frontiers in cellular neuroscience
34330913	PRMT1-dependent regulation of RNA metabolism and DNA damage response sustains pancreatic ductal adenocarcinoma.	Virginia Giuliani	2021-07-30	Nature communications
32379587	Non-Histone Arginine Methylation by Protein Arginine Methyltransferases.	A Ayad Al-Hamashi	2020-01-01	Current protein & peptide science
37193698	PRMT1 mediated methylation of cGAS suppresses anti-tumor immunity.	Jing Liu	2023-05-17	Nature communications
26789238	Small Molecule Inhibitors of Protein Arginine Methyltransferases.	Hao Hu	2016-01-01	Expert opinion on investigational drugs
26575292	Cross-talk between PRMT1-mediated methylation and ubiquitylation on RBM15 controls RNA splicing.	Li Zhang	2015-11-17	eLife
35817785	Genomic instability genes in lung and colon adenocarcinoma indicate organ specificity of transcriptomic impact on Copy Number Alterations.	V Chinthalapally Rao	2022-07-11	Scientific reports
19095693	A feedback regulatory loop between methyltransferase PRMT1 and orphan receptor TR3.	Na-zi Lei	2009-02-01	Nucleic acids research
30741995	Downregulation of PRMT1 promotes the senescence and migration of a non-MYCN amplified neuroblastoma SK-N-SH cells.	Yu-Jen Lee	2019-02-11	Scientific reports
29358076	Mechanistic View of hnRNPA2 Low-Complexity Domain Structure, Interactions, and Phase Separation Altered by Mutation and Arginine Methylation.	H Veronica Ryan	2018-02-01	Molecular cell
28591869	Alternative splicing of CNOT7 diversifies CCR4-NOT functions.	Clément Chapat	2017-08-21	Nucleic acids research
11483748	The arginine-1493 residue in QRRGRTGR1493G motif IV of the hepatitis C virus NS3 helicase domain is essential for NS3 protein methylation by the protein arginine methyltransferase 1.	J Rho	2001-09-01	Journal of virology
28943242	CSNK1a1 Regulates PRMT1 to Maintain the Progenitor State in Self-Renewing Somatic Tissue.	Xiaomin Bao	2017-10-23	Developmental cell
35196489	A genome-scale CRISPR screen reveals PRMT1 as a critical regulator of androgen receptor signaling in prostate cancer.	Stephen Tang	2022-02-22	Cell reports
37342629	Protein Arginine Methyltransferase 1 Ablation in Motor Neurons Causes Mitochondrial Dysfunction Leading to Age-related Motor Neuron Degeneration with Muscle Loss.	Hyun-Kyung So	2023-01-01	Research (Washington, D.C.)
32629172	Modulating the modulators: regulation of protein arginine methyltransferases by post-translational modifications.	Antja-Voy Hartley	2020-09-01	Drug discovery today
34326297	Protein arginine methyltransferase 7 modulates neuronal excitability by interacting with NaV1.9.	Tingbin Ma	2022-04-01	Pain
23831234	The promise and failures of epigenetic therapies for cancer treatment.	Pasano Bojang	2014-02-01	Cancer treatment reviews

Name	Transcript ID	bp	Protein	Translation ID
PRMT1-212	ENST00000529284	1182	160aa	ENSP00000432349
PRMT1-217	ENST00000532489	1686	325aa	ENSP00000433556
PRMT1-207	ENST00000527382	699	205aa	ENSP00000432538
PRMT1-211	ENST00000528623	543	63aa	ENSP00000434911
PRMT1-219	ENST00000534465	779	207aa	ENSP00000431957
PRMT1-201	ENST00000391851	1393	353aa	ENSP00000375724
PRMT1-221	ENST00000610806	1192	285aa	ENSP00000484505
PRMT1-218	ENST00000534280	766	54aa	ENSP00000432050
PRMT1-220	ENST00000534676	915	No protein	-
PRMT1-205	ENST00000525915	298	No protein	-
PRMT1-202	ENST00000454376	1328	371aa	ENSP00000406162
PRMT1-204	ENST00000525616	780	No protein	-
PRMT1-203	ENST00000524771	713	238aa	ENSP00000433480
PRMT1-214	ENST00000529836	580	110aa	ENSP00000437273
PRMT1-206	ENST00000526224	578	160aa	ENSP00000432788
PRMT1-208	ENST00000527412	463	No protein	-
PRMT1-213	ENST00000529650	479	No protein	-
PRMT1-215	ENST00000530070	525	No protein	-
PRMT1-216	ENST00000530361	866	No protein	-
PRMT1-210	ENST00000528126	642	No protein	-
PRMT1-209	ENST00000527866	968	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000126457	homo_sapiens	ENSP00000314396	17.2781	9.23077	homo_sapiens	ENSP00000406162	39.3531	21.0243
ENSG00000126457	homo_sapiens	ENSP00000347906	45.4965	27.2517	homo_sapiens	ENSP00000406162	53.0997	31.8059
ENSG00000126457	homo_sapiens	ENSP00000409324	20.8092	10.9827	homo_sapiens	ENSP00000406162	38.814	20.4852
ENSG00000126457	homo_sapiens	ENSP00000372067	80.7107	70.5584	homo_sapiens	ENSP00000406162	85.7143	74.9326
ENSG00000126457	homo_sapiens	ENSP00000359095	47.7333	29.3333	homo_sapiens	ENSP00000406162	48.248	29.6496
ENSG00000126457	homo_sapiens	ENSP00000331879	44.0678	31.6384	homo_sapiens	ENSP00000406162	63.0728	45.283
ENSG00000126457	homo_sapiens	ENSP00000325690	32.0724	20.0658	homo_sapiens	ENSP00000406162	52.5606	32.8841

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000126457	homo_sapiens	ENSP00000406162	76.5499	72.5067	nomascus_leucogenys	ENSNLEP00000006410	87.9257	83.2817
ENSG00000126457	homo_sapiens	ENSP00000406162	100	100	pan_paniscus	ENSPPAP00000023756	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	100	100	pongo_abelii	ENSPPYP00000037886	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	100	100	pan_troglodytes	ENSPTRP00000068530	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	97.8437	97.5741	gorilla_gorilla	ENSGGOP00000033261	97.0588	96.7914
ENSG00000126457	homo_sapiens	ENSP00000406162	99.1914	97.5741	ornithorhynchus_anatinus	ENSOANP00000048469	99.1914	97.5741
ENSG00000126457	homo_sapiens	ENSP00000406162	72.7763	69.5418	sarcophilus_harrisii	ENSSHAP00000036317	80.1187	76.5579
ENSG00000126457	homo_sapiens	ENSP00000406162	99.1914	98.6523	dasypus_novemcinctus	ENSDNOP00000023756	99.1914	98.6523
ENSG00000126457	homo_sapiens	ENSP00000406162	53.0997	52.0216	erinaceus_europaeus	ENSEEUP00000012204	57.4344	56.2682
ENSG00000126457	homo_sapiens	ENSP00000406162	75.4717	73.8544	echinops_telfairi	ENSETEP00000006004	80.4598	78.7356
ENSG00000126457	homo_sapiens	ENSP00000406162	58.4906	53.6388	callithrix_jacchus	ENSCJAP00000078795	91.5612	83.9662
ENSG00000126457	homo_sapiens	ENSP00000406162	100	100	cercocebus_atys	ENSCATP00000036416	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	86.5229	85.4447	macaca_fascicularis	ENSMFAP00000023785	83.812	82.7676
ENSG00000126457	homo_sapiens	ENSP00000406162	100	100	macaca_mulatta	ENSMMUP00000004045	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	100	100	macaca_nemestrina	ENSMNEP00000001777	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	100	100	papio_anubis	ENSPANP00000034839	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	100	100	mandrillus_leucophaeus	ENSMLEP00000036244	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	96.7655	96.7655	tursiops_truncatus	ENSTTRP00000005225	99.7222	99.7222
ENSG00000126457	homo_sapiens	ENSP00000406162	100	100	vulpes_vulpes	ENSVVUP00000030504	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	95.1482	94.8787	mus_spretus	MGP_SPRETEiJ_P0082747	100	99.7167
ENSG00000126457	homo_sapiens	ENSP00000406162	100	99.7305	mus_spretus	MGP_SPRETEiJ_P0082746	100	99.7305
ENSG00000126457	homo_sapiens	ENSP00000406162	99.7305	99.7305	equus_asinus	ENSEASP00005008126	99.7305	99.7305
ENSG00000126457	homo_sapiens	ENSP00000406162	100	100	capra_hircus	ENSCHIP00000013677	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	100	99.7305	loxodonta_africana	ENSLAFP00000015131	100	99.7305
ENSG00000126457	homo_sapiens	ENSP00000406162	100	100	panthera_leo	ENSPLOP00000009991	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	95.1482	95.1482	ailuropoda_melanoleuca	ENSAMEP00000014628	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	92.4528	92.4528	bos_indicus_hybrid	ENSBIXP00005026421	98.8473	98.8473
ENSG00000126457	homo_sapiens	ENSP00000406162	99.4609	98.6523	oryctolagus_cuniculus	ENSOCUP00000023989	99.4609	98.6523
ENSG00000126457	homo_sapiens	ENSP00000406162	97.8437	97.3046	equus_caballus	ENSECAP00000062985	92.132	91.6244
ENSG00000126457	homo_sapiens	ENSP00000406162	100	100	canis_lupus_familiaris	ENSCAFP00845031439	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	100	100	panthera_pardus	ENSPPRP00000014475	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	100	100	marmota_marmota_marmota	ENSMMMP00000009881	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	88.9488	87.3315	balaenoptera_musculus	ENSBMSP00010029312	75.6881	74.3119
ENSG00000126457	homo_sapiens	ENSP00000406162	100	100	cavia_porcellus	ENSCPOP00000021439	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	100	100	felis_catus	ENSFCAP00000028530	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	58.221	51.2129	ursus_americanus	ENSUAMP00000035159	67.2897	59.19
ENSG00000126457	homo_sapiens	ENSP00000406162	95.1482	95.1482	ursus_americanus	ENSUAMP00000008888	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	93.8005	92.4528	monodelphis_domestica	ENSMODP00000017006	89.2308	87.9487
ENSG00000126457	homo_sapiens	ENSP00000406162	100	100	bison_bison_bison	ENSBBBP00000000978	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	99.7305	99.4609	monodon_monoceros	ENSMMNP00015006865	99.7305	99.4609
ENSG00000126457	homo_sapiens	ENSP00000406162	94.8787	94.3396	sus_scrofa	ENSSSCP00000059502	91.906	91.3838
ENSG00000126457	homo_sapiens	ENSP00000406162	94.6092	93.8005	microcebus_murinus	ENSMICP00000047478	88.8608	88.1013
ENSG00000126457	homo_sapiens	ENSP00000406162	68.1941	66.8464	octodon_degus	ENSODEP00000025093	94.7566	92.8839
ENSG00000126457	homo_sapiens	ENSP00000406162	100	99.4609	jaculus_jaculus	ENSJJAP00000016570	100	99.4609
ENSG00000126457	homo_sapiens	ENSP00000406162	100	100	ovis_aries_rambouillet	ENSOARP00020012743	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	65.4986	64.4205	ursus_maritimus	ENSUMAP00000002973	84.965	83.5664
ENSG00000126457	homo_sapiens	ENSP00000406162	91.6442	91.6442	ochotona_princeps	ENSOPRP00000001852	99.7067	99.7067
ENSG00000126457	homo_sapiens	ENSP00000406162	94.8787	94.6092	delphinapterus_leucas	ENSDLEP00000007176	99.7167	99.4334
ENSG00000126457	homo_sapiens	ENSP00000406162	99.7305	99.7305	physeter_catodon	ENSPCTP00005015315	99.7305	99.7305
ENSG00000126457	homo_sapiens	ENSP00000406162	94.8787	94.6092	mus_caroli	MGP_CAROLIEiJ_P0079413	99.7167	99.4334
ENSG00000126457	homo_sapiens	ENSP00000406162	99.7305	99.4609	mus_caroli	MGP_CAROLIEiJ_P0079412	99.7305	99.4609
ENSG00000126457	homo_sapiens	ENSP00000406162	100	99.7305	mus_musculus	ENSMUSP00000103474	100	99.7305
ENSG00000126457	homo_sapiens	ENSP00000406162	100	100	dipodomys_ordii	ENSDORP00000026679	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	100	100	mustela_putorius_furo	ENSMPUP00000002374	99.1979	99.1979
ENSG00000126457	homo_sapiens	ENSP00000406162	99.1914	99.1914	aotus_nancymaae	ENSANAP00000007799	98.9247	98.9247
ENSG00000126457	homo_sapiens	ENSP00000406162	90.566	90.027	saimiri_boliviensis_boliviensis	ENSSBOP00000008368	85.0633	84.557
ENSG00000126457	homo_sapiens	ENSP00000406162	82.4798	82.4798	chlorocebus_sabaeus	ENSCSAP00000015569	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	60.6469	60.3774	tupaia_belangeri	ENSTBEP00000004565	82.4176	82.0513
ENSG00000126457	homo_sapiens	ENSP00000406162	99.7305	98.9218	mesocricetus_auratus	ENSMAUP00000004572	99.7305	98.9218
ENSG00000126457	homo_sapiens	ENSP00000406162	87.3315	86.2534	camelus_dromedarius	ENSCDRP00005011807	87.3315	86.2534
ENSG00000126457	homo_sapiens	ENSP00000406162	100	100	carlito_syrichta	ENSTSYP00000020075	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	78.1671	76.2803	panthera_tigris_altaica	ENSPTIP00000022210	84.5481	82.5073
ENSG00000126457	homo_sapiens	ENSP00000406162	86.5229	86.2534	rattus_norvegicus	ENSRNOP00000075012	99.6894	99.3789
ENSG00000126457	homo_sapiens	ENSP00000406162	31.8059	26.4151	rattus_norvegicus	ENSRNOP00000093348	68.2081	56.6474
ENSG00000126457	homo_sapiens	ENSP00000406162	95.6873	94.3396	rattus_norvegicus	ENSRNOP00000078126	96.7302	95.3678
ENSG00000126457	homo_sapiens	ENSP00000406162	99.7305	99.4609	prolemur_simus	ENSPSMP00000032601	99.7305	99.4609
ENSG00000126457	homo_sapiens	ENSP00000406162	26.9542	26.4151	microtus_ochrogaster	ENSMOCP00000004742	89.2857	87.5
ENSG00000126457	homo_sapiens	ENSP00000406162	61.186	61.186	sorex_araneus	ENSSARP00000005681	73.9414	73.9414
ENSG00000126457	homo_sapiens	ENSP00000406162	100	99.4609	peromyscus_maniculatus_bairdii	ENSPEMP00000014540	100	99.4609
ENSG00000126457	homo_sapiens	ENSP00000406162	100	100	bos_mutus	ENSBMUP00000005581	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	96.7655	96.496	mus_spicilegus	ENSMSIP00000024648	100	99.7215
ENSG00000126457	homo_sapiens	ENSP00000406162	99.7305	99.1914	cricetulus_griseus_chok1gshd	ENSCGRP00001018486	99.7305	99.1914
ENSG00000126457	homo_sapiens	ENSP00000406162	81.6712	81.6712	pteropus_vampyrus	ENSPVAP00000017032	86.0795	86.0795
ENSG00000126457	homo_sapiens	ENSP00000406162	82.4798	82.2102	myotis_lucifugus	ENSMLUP00000020505	99.6743	99.3485
ENSG00000126457	homo_sapiens	ENSP00000406162	99.1914	97.5741	vombatus_ursinus	ENSVURP00010017902	98.9247	97.3118
ENSG00000126457	homo_sapiens	ENSP00000406162	95.1482	95.1482	rhinolophus_ferrumequinum	ENSRFEP00010015077	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	100	100	neovison_vison	ENSNVIP00000017883	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	93.8005	93.531	bos_taurus	ENSBTAP00000074556	93.2976	93.0295
ENSG00000126457	homo_sapiens	ENSP00000406162	56.0647	56.0647	heterocephalus_glaber_female	ENSHGLP00000008790	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	100	100	rhinopithecus_bieti	ENSRBIP00000027066	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	100	100	canis_lupus_dingo	ENSCAFP00020031813	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	100	100	sciurus_vulgaris	ENSSVLP00005027148	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	99.1914	97.5741	phascolarctos_cinereus	ENSPCIP00000009604	98.9247	97.3118
ENSG00000126457	homo_sapiens	ENSP00000406162	84.097	84.097	procavia_capensis	ENSPCAP00000008146	86.6667	86.6667
ENSG00000126457	homo_sapiens	ENSP00000406162	96.2264	95.6873	nannospalax_galili	ENSNGAP00000018624	95.7105	95.1743
ENSG00000126457	homo_sapiens	ENSP00000406162	92.9919	92.7224	bos_grunniens	ENSBGRP00000037595	95.8333	95.5556
ENSG00000126457	homo_sapiens	ENSP00000406162	100	100	chinchilla_lanigera	ENSCLAP00000005359	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	52.0216	46.9003	cervus_hanglu_yarkandensis	ENSCHYP00000014067	71.7472	64.684
ENSG00000126457	homo_sapiens	ENSP00000406162	89.4879	88.9488	cervus_hanglu_yarkandensis	ENSCHYP00000004461	72.807	72.3684
ENSG00000126457	homo_sapiens	ENSP00000406162	95.1482	95.1482	catagonus_wagneri	ENSCWAP00000008748	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	100	100	ictidomys_tridecemlineatus	ENSSTOP00000024079	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	94.8787	94.8787	otolemur_garnettii	ENSOGAP00000010681	99.7167	99.7167
ENSG00000126457	homo_sapiens	ENSP00000406162	65.2291	59.0296	cebus_imitator	ENSCCAP00000037716	87.6812	79.3478
ENSG00000126457	homo_sapiens	ENSP00000406162	100	100	urocitellus_parryii	ENSUPAP00010017494	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	50.4043	46.9003	moschus_moschiferus	ENSMMSP00000013881	68.4982	63.7363
ENSG00000126457	homo_sapiens	ENSP00000406162	100	100	moschus_moschiferus	ENSMMSP00000003217	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	100	100	rhinopithecus_roxellana	ENSRROP00000031480	100	100
ENSG00000126457	homo_sapiens	ENSP00000406162	95.1482	94.8787	mus_pahari	MGP_PahariEiJ_P0016281	100	99.7167
ENSG00000126457	homo_sapiens	ENSP00000406162	100	99.7305	mus_pahari	MGP_PahariEiJ_P0016280	100	99.7305
ENSG00000126457	homo_sapiens	ENSP00000406162	99.7305	99.7305	propithecus_coquereli	ENSPCOP00000005716	99.7305	99.7305
ENSG00000126457	homo_sapiens	ENSP00000406162	57.4124	38.0054	drosophila_melanogaster	FBpp0311769	60	39.7183
ENSG00000126457	homo_sapiens	ENSP00000406162	34.5013	26.4151	ciona_intestinalis	ENSCINP00000015404	86.4865	66.2162
ENSG00000126457	homo_sapiens	ENSP00000406162	19.1375	16.7116	ciona_intestinalis	ENSCINP00000015406	88.75	77.5
ENSG00000126457	homo_sapiens	ENSP00000406162	85.1752	74.124	petromyzon_marinus	ENSPMAP00000007105	89.7727	78.125
ENSG00000126457	homo_sapiens	ENSP00000406162	82.7493	73.0458	eptatretus_burgeri	ENSEBUP00000003591	63.039	55.6468
ENSG00000126457	homo_sapiens	ENSP00000406162	19.6765	16.9811	callorhinchus_milii	ENSCMIP00000009479	90.1235	77.7778
ENSG00000126457	homo_sapiens	ENSP00000406162	79.2453	74.6631	latimeria_chalumnae	ENSLACP00000019867	91.875	86.5625
ENSG00000126457	homo_sapiens	ENSP00000406162	89.7574	83.2884	clupea_harengus	ENSCHAP00000011437	86.9452	80.6788
ENSG00000126457	homo_sapiens	ENSP00000406162	89.4879	84.3666	danio_rerio	ENSDARP00000010384	95.4023	89.9425
ENSG00000126457	homo_sapiens	ENSP00000406162	90.027	84.3666	carassius_auratus	ENSCARP00000006117	86.0825	80.6701
ENSG00000126457	homo_sapiens	ENSP00000406162	89.7574	82.7493	carassius_auratus	ENSCARP00000058896	90.4891	83.4239
ENSG00000126457	homo_sapiens	ENSP00000406162	88.6792	82.2102	carassius_auratus	ENSCARP00000069796	92.4157	85.6742
ENSG00000126457	homo_sapiens	ENSP00000406162	90.2965	84.6361	astyanax_mexicanus	ENSAMXP00000040214	92.5414	86.7403
ENSG00000126457	homo_sapiens	ENSP00000406162	90.566	83.8275	ictalurus_punctatus	ENSIPUP00000009561	89.3617	82.7128
ENSG00000126457	homo_sapiens	ENSP00000406162	87.062	80.3234	esox_lucius	ENSELUP00000052190	90.4762	83.4734
ENSG00000126457	homo_sapiens	ENSP00000406162	89.4879	82.4798	esox_lucius	ENSELUP00000057815	92.7374	85.4749
ENSG00000126457	homo_sapiens	ENSP00000406162	89.7574	83.8275	electrophorus_electricus	ENSEEEP00000033899	95.6897	89.3678
ENSG00000126457	homo_sapiens	ENSP00000406162	90.2965	82.7493	oncorhynchus_kisutch	ENSOKIP00005067949	88.3905	81.0026
ENSG00000126457	homo_sapiens	ENSP00000406162	90.2965	82.4798	oncorhynchus_kisutch	ENSOKIP00005070756	87.6963	80.1047
ENSG00000126457	homo_sapiens	ENSP00000406162	88.9488	81.9407	oncorhynchus_mykiss	ENSOMYP00000120593	92.6966	85.3933
ENSG00000126457	homo_sapiens	ENSP00000406162	85.7143	79.7844	oncorhynchus_mykiss	ENSOMYP00000103021	79.3017	73.8155
ENSG00000126457	homo_sapiens	ENSP00000406162	89.7574	82.4798	salmo_salar	ENSSSAP00000001599	92.7577	85.2368
ENSG00000126457	homo_sapiens	ENSP00000406162	89.7574	81.9407	salmo_salar	ENSSSAP00000073896	90.2439	82.3848
ENSG00000126457	homo_sapiens	ENSP00000406162	90.027	82.2102	salmo_trutta	ENSSTUP00000069227	89.7849	81.9893
ENSG00000126457	homo_sapiens	ENSP00000406162	83.8275	77.628	salmo_trutta	ENSSTUP00000052412	82.2751	76.1905
ENSG00000126457	homo_sapiens	ENSP00000406162	91.1051	83.2884	gadus_morhua	ENSGMOP00000041467	85.5696	78.2279
ENSG00000126457	homo_sapiens	ENSP00000406162	88.1402	83.558	fundulus_heteroclitus	ENSFHEP00000017334	88.1402	83.558
ENSG00000126457	homo_sapiens	ENSP00000406162	82.4798	79.2453	poecilia_reticulata	ENSPREP00000009284	79.8956	76.7624
ENSG00000126457	homo_sapiens	ENSP00000406162	88.1402	83.2884	xiphophorus_maculatus	ENSXMAP00000010881	93.9655	88.7931
ENSG00000126457	homo_sapiens	ENSP00000406162	88.1402	83.0189	oryzias_latipes	ENSORLP00000021497	93.9655	88.5057
ENSG00000126457	homo_sapiens	ENSP00000406162	88.6792	83.0189	cyclopterus_lumpus	ENSCLMP00005043107	89.8907	84.153
ENSG00000126457	homo_sapiens	ENSP00000406162	87.3315	81.9407	oreochromis_niloticus	ENSONIP00000076627	74.6544	70.0461
ENSG00000126457	homo_sapiens	ENSP00000406162	87.3315	82.2102	haplochromis_burtoni	ENSHBUP00000016691	94.186	88.6628
ENSG00000126457	homo_sapiens	ENSP00000406162	84.9057	79.7844	astatotilapia_calliptera	ENSACLP00000016428	96.3303	90.5199
ENSG00000126457	homo_sapiens	ENSP00000406162	88.9488	83.8275	sparus_aurata	ENSSAUP00010061254	92.9577	87.6056
ENSG00000126457	homo_sapiens	ENSP00000406162	90.027	85.7143	lates_calcarifer	ENSLCAP00010031458	63.2576	60.2273
ENSG00000126457	homo_sapiens	ENSP00000406162	95.4178	91.9137	xenopus_tropicalis	ENSXETP00000006288	97.5207	93.9394
ENSG00000126457	homo_sapiens	ENSP00000406162	80.0539	76.5499	chrysemys_picta_bellii	ENSCPBP00000008531	84.136	80.4533
ENSG00000126457	homo_sapiens	ENSP00000406162	73.5849	70.3504	sphenodon_punctatus	ENSSPUP00000011864	79.8246	76.3158
ENSG00000126457	homo_sapiens	ENSP00000406162	92.7224	90.2965	laticauda_laticaudata	ENSLLTP00000018588	98.5673	95.9885
ENSG00000126457	homo_sapiens	ENSP00000406162	92.9919	90.8356	notechis_scutatus	ENSNSUP00000007459	98.5714	96.2857
ENSG00000126457	homo_sapiens	ENSP00000406162	97.3046	94.8787	pseudonaja_textilis	ENSPTXP00000022135	98.0978	95.6522
ENSG00000126457	homo_sapiens	ENSP00000406162	64.1509	60.9164	serinus_canaria	ENSSCAP00000010743	93.7008	88.9764
ENSG00000126457	homo_sapiens	ENSP00000406162	97.3046	94.8787	anolis_carolinensis	ENSACAP00000004792	97.5676	95.1351
ENSG00000126457	homo_sapiens	ENSP00000406162	81.4016	75.7412	neolamprologus_brichardi	ENSNBRP00000003838	90.1493	83.8806
ENSG00000126457	homo_sapiens	ENSP00000406162	97.3046	94.8787	naja_naja	ENSNNAP00000016302	98.0978	95.6522
ENSG00000126457	homo_sapiens	ENSP00000406162	92.9919	90.8356	podarcis_muralis	ENSPMRP00000027726	89.3782	87.3057
ENSG00000126457	homo_sapiens	ENSP00000406162	56.3342	52.5606	taeniopygia_guttata	ENSTGUP00000034375	84.9594	79.2683
ENSG00000126457	homo_sapiens	ENSP00000406162	68.1941	66.0377	taeniopygia_guttata	ENSTGUP00000024659	89.7163	86.8794
ENSG00000126457	homo_sapiens	ENSP00000406162	84.9057	77.8976	erpetoichthys_calabaricus	ENSECRP00000025410	86.7769	79.6143
ENSG00000126457	homo_sapiens	ENSP00000406162	92.4528	85.7143	erpetoichthys_calabaricus	ENSECRP00000013641	83.8631	77.7506
ENSG00000126457	homo_sapiens	ENSP00000406162	88.1402	83.2884	kryptolebias_marmoratus	ENSKMAP00000007347	94.2363	89.049
ENSG00000126457	homo_sapiens	ENSP00000406162	97.3046	94.6092	salvator_merianae	ENSSMRP00000005137	97.832	95.1219
ENSG00000126457	homo_sapiens	ENSP00000406162	88.1402	83.558	oryzias_javanicus	ENSOJAP00000040594	93.9655	89.0805
ENSG00000126457	homo_sapiens	ENSP00000406162	84.6361	79.7844	amphilophus_citrinellus	ENSACIP00000022959	96.6154	91.0769
ENSG00000126457	homo_sapiens	ENSP00000406162	89.4879	84.6361	dicentrarchus_labrax	ENSDLAP00005013608	84.9105	80.3069
ENSG00000126457	homo_sapiens	ENSP00000406162	84.9057	79.7844	amphiprion_percula	ENSAPEP00000003398	96.9231	91.0769
ENSG00000126457	homo_sapiens	ENSP00000406162	88.4097	82.4798	oryzias_sinensis	ENSOSIP00000008739	83.6735	78.0612
ENSG00000126457	homo_sapiens	ENSP00000406162	91.6442	88.4097	gopherus_evgoodei	ENSGEVP00005019156	83.9506	80.9877
ENSG00000126457	homo_sapiens	ENSP00000406162	53.9084	52.0216	chelonoidis_abingdonii	ENSCABP00000025316	96.6184	93.2367
ENSG00000126457	homo_sapiens	ENSP00000406162	88.6792	84.3666	seriola_dumerili	ENSSDUP00000024582	95.3623	90.7246
ENSG00000126457	homo_sapiens	ENSP00000406162	88.9488	83.0189	cottoperca_gobio	ENSCGOP00000029789	90.6593	84.6154
ENSG00000126457	homo_sapiens	ENSP00000406162	88.9488	83.2884	gasterosteus_aculeatus	ENSGACP00000006490	94.8276	88.7931
ENSG00000126457	homo_sapiens	ENSP00000406162	89.4879	84.6361	cynoglossus_semilaevis	ENSCSEP00000018321	93.2584	88.2022
ENSG00000126457	homo_sapiens	ENSP00000406162	88.1402	83.2884	poecilia_formosa	ENSPFOP00000009428	93.9655	88.7931
ENSG00000126457	homo_sapiens	ENSP00000406162	90.566	83.8275	myripristis_murdjan	ENSMMDP00005043880	90.8108	84.0541
ENSG00000126457	homo_sapiens	ENSP00000406162	90.8356	83.558	sander_lucioperca	ENSSLUP00000038149	88.9182	81.7942
ENSG00000126457	homo_sapiens	ENSP00000406162	88.6792	83.558	amphiprion_ocellaris	ENSAOCP00000025146	94.5402	89.0805
ENSG00000126457	homo_sapiens	ENSP00000406162	33.1536	29.6496	terrapene_carolina_triunguis	ENSTMTP00000023186	56.682	50.6912
ENSG00000126457	homo_sapiens	ENSP00000406162	90.2965	82.2102	hucho_hucho	ENSHHUP00000013773	88.6243	80.6878
ENSG00000126457	homo_sapiens	ENSP00000406162	90.566	83.0189	hucho_hucho	ENSHHUP00000028799	87.5	80.2083
ENSG00000126457	homo_sapiens	ENSP00000406162	88.4097	82.4798	betta_splendens	ENSBSLP00000011840	90.8587	84.7645
ENSG00000126457	homo_sapiens	ENSP00000406162	89.7574	83.8275	pygocentrus_nattereri	ENSPNAP00000012310	95.6897	89.3678
ENSG00000126457	homo_sapiens	ENSP00000406162	89.4879	84.9057	anabas_testudineus	ENSATEP00000049715	80.9756	76.8293
ENSG00000126457	homo_sapiens	ENSP00000406162	79.7844	68.1941	ciona_savignyi	ENSCSAVP00000013969	83.3803	71.2676
ENSG00000126457	homo_sapiens	ENSP00000406162	62.8032	45.5526	saccharomyces_cerevisiae	YBR034C	66.954	48.5632
ENSG00000126457	homo_sapiens	ENSP00000406162	88.6792	84.3666	seriola_lalandi_dorsalis	ENSSLDP00000012421	95.3623	90.7246
ENSG00000126457	homo_sapiens	ENSP00000406162	82.4798	77.089	labrus_bergylta	ENSLBEP00000003928	96.2264	89.9371
ENSG00000126457	homo_sapiens	ENSP00000406162	73.3154	68.4636	labrus_bergylta	ENSLBEP00000028679	91.8919	85.8108
ENSG00000126457	homo_sapiens	ENSP00000406162	84.9057	79.7844	pundamilia_nyererei	ENSPNYP00000004340	96.3303	90.5199
ENSG00000126457	homo_sapiens	ENSP00000406162	88.9488	84.097	mastacembelus_armatus	ENSMAMP00000050020	86.6142	81.8898
ENSG00000126457	homo_sapiens	ENSP00000406162	80.8625	75.2022	stegastes_partitus	ENSSPAP00000000408	95.8466	89.1374
ENSG00000126457	homo_sapiens	ENSP00000406162	84.9057	78.7062	oncorhynchus_tshawytscha	ENSOTSP00005019094	88.983	82.4859
ENSG00000126457	homo_sapiens	ENSP00000406162	89.4879	82.7493	oncorhynchus_tshawytscha	ENSOTSP00005009947	77.2093	71.3953
ENSG00000126457	homo_sapiens	ENSP00000406162	87.3315	82.2102	acanthochromis_polyacanthus	ENSAPOP00000019124	86.1702	81.117
ENSG00000126457	homo_sapiens	ENSP00000406162	87.8706	83.0189	nothobranchius_furzeri	ENSNFUP00015046962	91.831	86.7606
ENSG00000126457	homo_sapiens	ENSP00000406162	88.1402	82.7493	cyprinodon_variegatus	ENSCVAP00000002731	74.4875	69.9317
ENSG00000126457	homo_sapiens	ENSP00000406162	88.9488	83.558	denticeps_clupeoides	ENSDCDP00000011380	81.8859	76.9231
ENSG00000126457	homo_sapiens	ENSP00000406162	89.2183	82.7493	larimichthys_crocea	ENSLCRP00005022257	81.5271	75.6158
ENSG00000126457	homo_sapiens	ENSP00000406162	89.2183	83.0189	takifugu_rubripes	ENSTRUP00000063427	90.1907	83.9237
ENSG00000126457	homo_sapiens	ENSP00000406162	87.8706	82.2102	hippocampus_comes	ENSHCOP00000008510	93.6782	87.6437
ENSG00000126457	homo_sapiens	ENSP00000406162	89.7574	84.3666	cyprinus_carpio_carpio	ENSCCRP00000136156	88.0952	82.8042
ENSG00000126457	homo_sapiens	ENSP00000406162	90.2965	83.8275	cyprinus_carpio_carpio	ENSCCRP00000134550	89.0957	82.7128
ENSG00000126457	homo_sapiens	ENSP00000406162	87.6011	82.7493	poecilia_latipinna	ENSPLAP00000020601	94.2029	88.9855
ENSG00000126457	homo_sapiens	ENSP00000406162	30.7278	26.6846	sinocyclocheilus_grahami	ENSSGRP00000073299	95	82.5
ENSG00000126457	homo_sapiens	ENSP00000406162	90.2965	84.6361	sinocyclocheilus_grahami	ENSSGRP00000111879	87.9265	82.4147
ENSG00000126457	homo_sapiens	ENSP00000406162	84.9057	79.7844	maylandia_zebra	ENSMZEP00005030694	96.3303	90.5199
ENSG00000126457	homo_sapiens	ENSP00000406162	48.5175	44.2049	tetraodon_nigroviridis	ENSTNIP00000005906	96.7742	88.172
ENSG00000126457	homo_sapiens	ENSP00000406162	89.2183	80.8625	paramormyrops_kingsleyae	ENSPKIP00000022427	95.389	86.4553
ENSG00000126457	homo_sapiens	ENSP00000406162	88.1402	83.0189	paramormyrops_kingsleyae	ENSPKIP00000001330	94.5087	89.0173
ENSG00000126457	homo_sapiens	ENSP00000406162	91.6442	83.558	scleropages_formosus	ENSSFOP00015053082	79.0698	72.093
ENSG00000126457	homo_sapiens	ENSP00000406162	90.027	79.5148	scleropages_formosus	ENSSFOP00015074183	86.5285	76.4249
ENSG00000126457	homo_sapiens	ENSP00000406162	95.1482	90.566	leptobrachium_leishanense	ENSLLEP00000016373	95.4054	90.8108
ENSG00000126457	homo_sapiens	ENSP00000406162	88.9488	82.4798	scophthalmus_maximus	ENSSMAP00000035262	84.399	78.2609
ENSG00000126457	homo_sapiens	ENSP00000406162	88.1402	83.558	oryzias_melastigma	ENSOMEP00000011548	93.9655	89.0805

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0001701	involved_in in utero embryonic development	1	IEA	Homo_sapiens(9606)	Process
GO:0003723	enables RNA binding	1	HDA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	is_active_in nucleus	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0005654	located_in nucleoplasm	2	IDA,TAS	Homo_sapiens(9606)	Component
GO:0005737	located_in cytoplasm	1	IDA	Homo_sapiens(9606)	Component
GO:0005829	located_in cytosol	1	TAS	Homo_sapiens(9606)	Component
GO:0006338	involved_in chromatin remodeling	1	IEA	Homo_sapiens(9606)	Process
GO:0006479	involved_in protein methylation	1	IMP	Homo_sapiens(9606)	Process
GO:0007166	involved_in cell surface receptor signaling pathway	1	TAS	Homo_sapiens(9606)	Process
GO:0008168	enables methyltransferase activity	1	TAS	Homo_sapiens(9606)	Function
GO:0008170	enables N-methyltransferase activity	2	IDA,IMP	Homo_sapiens(9606)	Function
GO:0008276	enables protein methyltransferase activity	3	IDA,IMP,TAS	Homo_sapiens(9606)	Function
GO:0008284	involved_in positive regulation of cell population proliferation	1	IMP	Homo_sapiens(9606)	Process
GO:0008327	enables methyl-CpG binding	1	IDA	Homo_sapiens(9606)	Function
GO:0008380	involved_in RNA splicing	1	ISS	Homo_sapiens(9606)	Process
GO:0016274	enables protein-arginine N-methyltransferase activity	3	EXP,IDA,TAS	Homo_sapiens(9606)	Function
GO:0018216	involved_in peptidyl-arginine methylation	1	IDA	Homo_sapiens(9606)	Process
GO:0019082	involved_in viral protein processing	1	TAS	Homo_sapiens(9606)	Process
GO:0019899	enables enzyme binding	1	IPI	Homo_sapiens(9606)	Function
GO:0031175	involved_in neuron projection development	1	IMP	Homo_sapiens(9606)	Process
GO:0034709	part_of methylosome	1	IDA	Homo_sapiens(9606)	Component
GO:0035241	enables protein-arginine omega-N monomethyltransferase activity	1	IDA	Homo_sapiens(9606)	Function
GO:0035242	enables protein-arginine omega-N asymmetric methyltransferase activity	3	IDA,IMP,TAS	Homo_sapiens(9606)	Function
GO:0042054	enables histone methyltransferase activity	1	IDA	Homo_sapiens(9606)	Function
GO:0042802	enables identical protein binding	2	IDA,IPI	Homo_sapiens(9606)	Function
GO:0044020	enables histone H4R3 methyltransferase activity	2	IDA,IMP	Homo_sapiens(9606)	Function
GO:0045648	involved_in positive regulation of erythrocyte differentiation	1	IMP	Homo_sapiens(9606)	Process
GO:0045652	involved_in regulation of megakaryocyte differentiation	2	IDA,TAS	Homo_sapiens(9606)	Process
GO:0045653	involved_in negative regulation of megakaryocyte differentiation	1	IDA	Homo_sapiens(9606)	Process
GO:0045727	involved_in positive regulation of translation	1	IDA	Homo_sapiens(9606)	Process
GO:0046329	involved_in negative regulation of JNK cascade	1	IMP	Homo_sapiens(9606)	Process
GO:0046985	involved_in positive regulation of hemoglobin biosynthetic process	1	ISS	Homo_sapiens(9606)	Process
GO:0048273	enables mitogen-activated protein kinase p38 binding	1	IPI	Homo_sapiens(9606)	Function
GO:0048738	involved_in cardiac muscle tissue development	1	ISS	Homo_sapiens(9606)	Process
GO:0051260	involved_in protein homooligomerization	1	IDA	Homo_sapiens(9606)	Process
GO:1900745	involved_in positive regulation of p38MAPK cascade	1	ISS	Homo_sapiens(9606)	Process
GO:1904047	enables S-adenosyl-L-methionine binding	1	IDA	Homo_sapiens(9606)	Function