Functions and Diseases

RBP Type Canonical_RBPs
Diseases N.A.
Drug N.A.
Main interacting RNAs ncRNA
Moonlighting functions N.A.
Localizations Stress granule or P-body
BulkPerturb-seq DataSet_01_75

Description

Ensembl ID ENSG00000126070 Gene ID 192669 Accession 18421
Symbol AGO3 Alias EIF2C3 Full Name argonaute RISC catalytic component 3
Status Confidence Length 141783 bases Strand Plus strand
Position 1 : 35930718 - 36072500 RNA binding domain Piwi , PAZ
Summary This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, contains a PAZ domain and a PIWI domain, and may play a role in short-interfering-RNA-mediated gene silencing. This gene is located on chromosome 1 in a tandem cluster of closely related family members including argonaute 4 and eukaryotic translation initiation factor 2C, 1. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000246314 Piwi PF02171 2.3e-113 1
ENSP00000246314 PAZ PF02170 1.9e-28 2
ENSP00000362287 Piwi PF02171 4.9e-113 1
ENSP00000362287 PAZ PF02170 3e-28 2

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
33507586 tsRNAs: Novel small molecules from cell function and regulatory mechanism to therapeutic targets. Tingyu Zong 2021-03-01 Cell proliferation
23239791 Non-micro-short RNAs: the new kids on the block. K Bijan Dey 2012-12-01 Molecular biology of the cell
32049003 A Requirement for Argonaute 4 in Mammalian Antiviral Defense. Fatemeh Adiliaghdam 2020-02-11 Cell reports
21878547 Argonaute protein identity and pairing geometry determine cooperativity in mammalian RNA silencing. A Jennifer Broderick 2011-10-01 RNA (New York, N.Y.)
35736234 Anatomy of four human Argonaute proteins. Kotaro Nakanishi 2022-07-08 Nucleic acids research
18771919 Importance of translation and nonnucleolytic ago proteins for on-target RNA interference. Ligang Wu 2008-09-09 Current biology : CB
34118972 The biogenesis and biological function of PIWI-interacting RNA in cancer. Silu Chen 2021-06-12 Journal of hematology & oncology
31585876 AGO unchained: Canonical and non-canonical roles of Argonaute proteins in mammals. Laura Sala 2020-01-01 Frontiers in bioscience (Landmark edition)

Transcripts

Name Transcript ID bp Protein Translation ID
AGO3-202 ENST00000324350 1726 229aa ENSP00000317425
AGO3-204 ENST00000397828 1035 229aa ENSP00000380928
AGO3-207 ENST00000634486 3599 64aa ENSP00000489286
AGO3-203 ENST00000373191 19660 860aa ENSP00000362287
AGO3-201 ENST00000246314 3211 626aa ENSP00000246314
AGO3-206 ENST00000491443 548 No protein -
AGO3-205 ENST00000471099 602 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000126070homo_sapiensENSP0000022059289.173579.9767homo_sapiensENSP0000036228789.069879.8837
ENSG00000126070homo_sapiensENSP0000036230689.54781.7654homo_sapiensENSP0000036228789.651281.8605
ENSG00000126070homo_sapiensENSP0000036230091.948784.9475homo_sapiensENSP0000036228791.627984.6512

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000126070homo_sapiensENSP0000036228795.697795.1163nomascus_leucogenysENSNLEP0000001360397.396496.8047
ENSG00000126070homo_sapiensENSP00000362287100100pan_paniscusENSPPAP00000017917100100
ENSG00000126070homo_sapiensENSP00000362287100100pongo_abeliiENSPPYP00000001788100100
ENSG00000126070homo_sapiensENSP00000362287100100pan_troglodytesENSPTRP00000000933100100
ENSG00000126070homo_sapiensENSP00000362287100100gorilla_gorillaENSGGOP00000013421100100
ENSG00000126070homo_sapiensENSP0000036228799.534999.4186ornithorhynchus_anatinusENSOANP0000000329699.188999.073
ENSG00000126070homo_sapiensENSP0000036228799.18698.9535sarcophilus_harrisiiENSSHAP0000002317799.18698.9535
ENSG00000126070homo_sapiensENSP0000036228773.604773.3721notamacropus_eugeniiENSMEUP0000000841077.668777.4233
ENSG00000126070homo_sapiensENSP0000036228781.744281.1628choloepus_hoffmanniENSCHOP0000001028083.790283.1943
ENSG00000126070homo_sapiensENSP0000036228788.023388.0233dasypus_novemcinctusENSDNOP0000000629199.868199.8681
ENSG00000126070homo_sapiensENSP0000036228782.90782.907erinaceus_europaeusENSEEUP0000000646482.90782.907
ENSG00000126070homo_sapiensENSP0000036228774.069873.6047echinops_telfairiENSETEP0000000620378.159577.6687
ENSG00000126070homo_sapiensENSP00000362287100100callithrix_jacchusENSCJAP00000002912100100
ENSG00000126070homo_sapiensENSP00000362287100100cercocebus_atysENSCATP00000011254100100
ENSG00000126070homo_sapiensENSP00000362287100100macaca_mulattaENSMMUP00000051045100100
ENSG00000126070homo_sapiensENSP00000362287100100macaca_nemestrinaENSMNEP00000032482100100
ENSG00000126070homo_sapiensENSP00000362287100100papio_anubisENSPANP00000035313100100
ENSG00000126070homo_sapiensENSP00000362287100100mandrillus_leucophaeusENSMLEP00000007907100100
ENSG00000126070homo_sapiensENSP0000036228790.930290.9302tursiops_truncatusENSTTRP0000001430591.676491.6764
ENSG00000126070homo_sapiensENSP0000036228798.255898.2558vulpes_vulpesENSVVUP00000000389100100
ENSG00000126070homo_sapiensENSP0000036228799.534999.3023mus_spretusMGP_SPRETEiJ_P006692099.534999.3023
ENSG00000126070homo_sapiensENSP0000036228789.534989.0698equus_asinusENSEASP0000501748397.099696.5952
ENSG00000126070homo_sapiensENSP0000036228799.883799.8837capra_hircusENSCHIP0000000856699.883799.8837
ENSG00000126070homo_sapiensENSP0000036228799.302399.186loxodonta_africanaENSLAFP0000002248899.071998.9559
ENSG00000126070homo_sapiensENSP0000036228799.883799.8837ailuropoda_melanoleucaENSAMEP0000000068999.883799.8837
ENSG00000126070homo_sapiensENSP0000036228799.534999.3023bos_indicus_hybridENSBIXP0000504349079.4879.2943
ENSG00000126070homo_sapiensENSP0000036228799.883799.8837oryctolagus_cuniculusENSOCUP0000000541199.883799.8837
ENSG00000126070homo_sapiensENSP0000036228799.418699.186equus_caballusENSECAP0000007758698.38998.1588
ENSG00000126070homo_sapiensENSP0000036228799.883799.8837canis_lupus_familiarisENSCAFP0084504327099.883799.8837
ENSG00000126070homo_sapiensENSP0000036228799.883799.8837panthera_pardusENSPPRP0000001237399.883799.8837
ENSG00000126070homo_sapiensENSP0000036228799.069899.0698marmota_marmota_marmotaENSMMMP0000000867499.882899.8828
ENSG00000126070homo_sapiensENSP0000036228799.883799.8837balaenoptera_musculusENSBMSP0001000156699.883799.8837
ENSG00000126070homo_sapiensENSP0000036228795.81495.5814cavia_porcellusENSCPOP0000002291599.637299.3954
ENSG00000126070homo_sapiensENSP0000036228795.697795.6977felis_catusENSFCAP0000005418999.757699.7576
ENSG00000126070homo_sapiensENSP0000036228798.255898.0233ursus_americanusENSUAMP0000003574396.461296.2329
ENSG00000126070homo_sapiensENSP0000036228799.418699.186monodelphis_domesticaENSMODP0000002227799.418699.186
ENSG00000126070homo_sapiensENSP0000036228799.883799.8837bison_bison_bisonENSBBBP0000001411499.883799.8837
ENSG00000126070homo_sapiensENSP0000036228799.534999.3023sus_scrofaENSSSCP0000000393662.710662.5641
ENSG00000126070homo_sapiensENSP0000036228799.883799.8837microcebus_murinusENSMICP0000001472599.883799.8837
ENSG00000126070homo_sapiensENSP0000036228799.651299.5349octodon_degusENSODEP0000000692198.960798.8453
ENSG00000126070homo_sapiensENSP0000036228799.767499.7674jaculus_jaculusENSJJAP0000001521099.767499.7674
ENSG00000126070homo_sapiensENSP0000036228799.883799.8837ovis_aries_rambouilletENSOARP0002001618099.883799.8837
ENSG00000126070homo_sapiensENSP0000036228743.837243.8372ursus_maritimusENSUMAP00000002278100100
ENSG00000126070homo_sapiensENSP0000036228725.930225.4651ursus_maritimusENSUMAP0000000230194.491592.7966
ENSG00000126070homo_sapiensENSP0000036228775.116375.1163ochotona_princepsENSOPRP0000001126775.203775.2037
ENSG00000126070homo_sapiensENSP0000036228792.90792.7907delphinapterus_leucasENSDLEP0000002894999.254799.1304
ENSG00000126070homo_sapiensENSP0000036228799.883799.8837physeter_catodonENSPCTP0000500567699.883799.8837
ENSG00000126070homo_sapiensENSP0000036228799.534999.186mus_caroliMGP_CAROLIEiJ_P006441499.534999.186
ENSG00000126070homo_sapiensENSP0000036228799.302398.9535mus_musculusENSMUSP0000006663399.302398.9535
ENSG00000126070homo_sapiensENSP0000036228799.883799.5349dipodomys_ordiiENSDORP0000002385899.883799.5349
ENSG00000126070homo_sapiensENSP0000036228717.90717.907mustela_putorius_furoENSMPUP0000001476095.652295.6522
ENSG00000126070homo_sapiensENSP00000362287100100aotus_nancymaaeENSANAP00000040860100100
ENSG00000126070homo_sapiensENSP00000362287100100saimiri_boliviensis_boliviensisENSSBOP00000027352100100
ENSG00000126070homo_sapiensENSP0000036228797.209397.093vicugna_pacosENSVPAP0000000709598.122198.0047
ENSG00000126070homo_sapiensENSP00000362287100100chlorocebus_sabaeusENSCSAP00000016921100100
ENSG00000126070homo_sapiensENSP0000036228775.348875.2326tupaia_belangeriENSTBEP0000001442175.348875.2326
ENSG00000126070homo_sapiensENSP0000036228783.255881.6279mesocricetus_auratusENSMAUP0000000882794.960293.1034
ENSG00000126070homo_sapiensENSP0000036228799.883799.8837phocoena_sinusENSPSNP0000002154299.883799.8837
ENSG00000126070homo_sapiensENSP0000036228799.883799.8837camelus_dromedariusENSCDRP0000500955499.883799.8837
ENSG00000126070homo_sapiensENSP0000036228784.069884.0698carlito_syrichtaENSTSYP0000001090999.861999.8619
ENSG00000126070homo_sapiensENSP0000036228799.069899.0698panthera_tigris_altaicaENSPTIP0000000053299.069899.0698
ENSG00000126070homo_sapiensENSP0000036228799.883799.6512rattus_norvegicusENSRNOP0000005051899.883799.6512
ENSG00000126070homo_sapiensENSP0000036228799.883799.8837prolemur_simusENSPSMP0000001099999.883799.8837
ENSG00000126070homo_sapiensENSP0000036228797.09396.2791microtus_ochrogasterENSMOCP0000002402098.816697.9882
ENSG00000126070homo_sapiensENSP0000036228783.953583.4884sorex_araneusENSSARP0000001044287.727887.2418
ENSG00000126070homo_sapiensENSP0000036228799.651299.3023peromyscus_maniculatus_bairdiiENSPEMP0000002885499.651299.3023
ENSG00000126070homo_sapiensENSP0000036228798.255898.2558bos_mutusENSBMUP00000029088100100
ENSG00000126070homo_sapiensENSP0000036228799.534999.3023mus_spicilegusENSMSIP0000001939799.534999.3023
ENSG00000126070homo_sapiensENSP0000036228799.767499.5349cricetulus_griseus_chok1gshdENSCGRP0000102767599.767499.5349
ENSG00000126070homo_sapiensENSP0000036228799.651299.5349pteropus_vampyrusENSPVAP0000000481299.651299.5349
ENSG00000126070homo_sapiensENSP0000036228772.790772.6744myotis_lucifugusENSMLUP0000000883010099.8403
ENSG00000126070homo_sapiensENSP0000036228799.534999.4186rhinolophus_ferrumequinumENSRFEP0001000263299.534999.4186
ENSG00000126070homo_sapiensENSP0000036228718.023317.7907neovison_visonENSNVIP0000001549567.685666.8122
ENSG00000126070homo_sapiensENSP0000036228799.883799.8837bos_taurusENSBTAP0000006384199.883799.8837
ENSG00000126070homo_sapiensENSP0000036228799.883799.8837heterocephalus_glaber_femaleENSHGLP0000001751499.883799.8837
ENSG00000126070homo_sapiensENSP00000362287100100rhinopithecus_bietiENSRBIP00000040746100100
ENSG00000126070homo_sapiensENSP0000036228798.953598.8372canis_lupus_dingoENSCAFP0002001138096.814696.7008
ENSG00000126070homo_sapiensENSP0000036228799.534999.5349sciurus_vulgarisENSSVLP0000500234499.534999.5349
ENSG00000126070homo_sapiensENSP0000036228799.302399.0698phascolarctos_cinereusENSPCIP0000000023099.302399.0698
ENSG00000126070homo_sapiensENSP0000036228786.627986.3953procavia_capensisENSPCAP0000000947387.441387.2066
ENSG00000126070homo_sapiensENSP0000036228799.767499.5349nannospalax_galiliENSNGAP0000001011299.767499.5349
ENSG00000126070homo_sapiensENSP0000036228799.883799.8837chinchilla_lanigeraENSCLAP0000001924099.883799.8837
ENSG00000126070homo_sapiensENSP0000036228799.883799.8837cervus_hanglu_yarkandensisENSCHYP0000004087399.883799.8837
ENSG00000126070homo_sapiensENSP000003622877.093026.97674catagonus_wagneriENSCWAP0000001235884.722283.3333
ENSG00000126070homo_sapiensENSP0000036228793.255893.2558catagonus_wagneriENSCWAP00000011427100100
ENSG00000126070homo_sapiensENSP0000036228795.116395.1163ictidomys_tridecemlineatusENSSTOP0000002346999.877999.8779
ENSG00000126070homo_sapiensENSP0000036228799.883799.8837otolemur_garnettiiENSOGAP0000000921599.883799.8837
ENSG00000126070homo_sapiensENSP00000362287100100cebus_imitatorENSCCAP00000032530100100
ENSG00000126070homo_sapiensENSP0000036228799.883799.7674urocitellus_parryiiENSUPAP0001000015599.883799.7674
ENSG00000126070homo_sapiensENSP0000036228799.883799.8837moschus_moschiferusENSMMSP0000001191899.883799.8837
ENSG00000126070homo_sapiensENSP00000362287100100rhinopithecus_roxellanaENSRROP00000037655100100
ENSG00000126070homo_sapiensENSP0000036228799.418699.0698mus_pahariMGP_PahariEiJ_P007950799.418699.0698
ENSG00000126070homo_sapiensENSP0000036228799.883799.8837propithecus_coquereliENSPCOP0000003126599.883799.8837
ENSG00000126070homo_sapiensENSP0000036228740.581424.7674caenorhabditis_elegansC18E3.7c.139.346124.0135
ENSG00000126070homo_sapiensENSP0000036228740.581424.8837caenorhabditis_elegansF56A6.1a.139.346124.1263
ENSG00000126070homo_sapiensENSP0000036228741.279123.4884caenorhabditis_elegansT22H9.3.135.858620.404
ENSG00000126070homo_sapiensENSP0000036228744.302325.4651caenorhabditis_elegansC16C10.3.136.918621.2209
ENSG00000126070homo_sapiensENSP0000036228741.279125.6977caenorhabditis_elegansR06C7.1.137.566123.3862
ENSG00000126070homo_sapiensENSP0000036228741.162825.4651caenorhabditis_elegansZK1248.7.138.815824.0132
ENSG00000126070homo_sapiensENSP0000036228757.90740caenorhabditis_elegansZK757.3a.147.884633.0769
ENSG00000126070homo_sapiensENSP0000036228757.790740.2326caenorhabditis_elegansT22B3.2b.148.019333.43
ENSG00000126070homo_sapiensENSP0000036228741.395324.6512caenorhabditis_elegansF58G1.1.136.891221.9689
ENSG00000126070homo_sapiensENSP0000036228741.860525.3488caenorhabditis_elegansY110A7A.18.136.923122.359
ENSG00000126070homo_sapiensENSP0000036228797.325694.7674clupea_harengusENSCHAP0000001802795.330392.8246
ENSG00000126070homo_sapiensENSP0000036228769.651268.9535clupea_harengusENSCHAP0000001450795.079494.127
ENSG00000126070homo_sapiensENSP0000036228798.372196.9767danio_rerioENSDARP0000007821297.577996.1938
ENSG00000126070homo_sapiensENSP0000036228797.790795.1163danio_rerioENSDARP0000008624697.790795.1163
ENSG00000126070homo_sapiensENSP0000036228743.255842.7907carassius_auratusENSCARP0000010945998.673797.6127
ENSG00000126070homo_sapiensENSP0000036228797.325694.6512carassius_auratusENSCARP0000006942796.428693.7788
ENSG00000126070homo_sapiensENSP0000036228724.302323.0233carassius_auratusENSCARP0000011162491.666786.8421
ENSG00000126070homo_sapiensENSP0000036228793.139590.6977carassius_auratusENSCARP0000011507291.963389.5522
ENSG00000126070homo_sapiensENSP0000036228785.697784.186carassius_auratusENSCARP0000011458997.101495.3887
ENSG00000126070homo_sapiensENSP0000036228798.023396.5116carassius_auratusENSCARP0000004444396.896695.4023
ENSG00000126070homo_sapiensENSP000003622877.093026.39535astyanax_mexicanusENSAMXP0000003095085.915577.4648
ENSG00000126070homo_sapiensENSP000003622878.139536.97674astyanax_mexicanusENSAMXP0000004482283.333371.4286
ENSG00000126070homo_sapiensENSP0000036228788.953586.9767astyanax_mexicanusENSAMXP0000000983798.582596.3918
ENSG00000126070homo_sapiensENSP0000036228789.18688.0233astyanax_mexicanusENSAMXP0000000244699.095697.8036
ENSG00000126070homo_sapiensENSP0000036228796.976793.9535ictalurus_punctatusENSIPUP0000001271395.205592.2374
ENSG00000126070homo_sapiensENSP0000036228793.139591.3953ictalurus_punctatusENSIPUP0000003461196.739194.9275
ENSG00000126070homo_sapiensENSP0000036228798.139596.6279esox_luciusENSELUP0000007446992.645491.2184
ENSG00000126070homo_sapiensENSP0000036228797.441995.1163esox_luciusENSELUP0000005859994.582492.3251
ENSG00000126070homo_sapiensENSP0000036228792.209390.4651electrophorus_electricusENSEEEP0000003714396.943895.11
ENSG00000126070homo_sapiensENSP0000036228795.465191.6279electrophorus_electricusENSEEEP0000001456095.576291.7346
ENSG00000126070homo_sapiensENSP0000036228797.674495.814oncorhynchus_kisutchENSOKIP0000504471294.808193.0023
ENSG00000126070homo_sapiensENSP0000036228798.023396.2791oncorhynchus_kisutchENSOKIP0000507772094.825693.1384
ENSG00000126070homo_sapiensENSP0000036228798.372196.9767oncorhynchus_kisutchENSOKIP0000503546496.136494.7727
ENSG00000126070homo_sapiensENSP0000036228796.860595oncorhynchus_mykissENSOMYP0000013797990.839789.0949
ENSG00000126070homo_sapiensENSP0000036228797.90795.9302oncorhynchus_mykissENSOMYP0000009023595.899893.9636
ENSG00000126070homo_sapiensENSP0000036228797.674495.9302salmo_salarENSSSAP0000009182595.346293.6436
ENSG00000126070homo_sapiensENSP0000036228797.441995.4651salmo_salarENSSSAP0000005409794.903792.9785
ENSG00000126070homo_sapiensENSP0000036228797.674496.2791salmo_salarENSSSAP0000009783394.915393.5593
ENSG00000126070homo_sapiensENSP0000036228798.720997.2093salmo_salarENSSSAP0000009168192.584591.1668
ENSG00000126070homo_sapiensENSP0000036228798.023396.1628salmo_truttaENSSTUP0000008549796.013794.1913
ENSG00000126070homo_sapiensENSP0000036228797.441995.4651salmo_truttaENSSTUP0000011380294.051692.1437
ENSG00000126070homo_sapiensENSP0000036228798.372196.8605salmo_truttaENSSTUP0000007940893.791692.3503
ENSG00000126070homo_sapiensENSP0000036228798.255896.1628gadus_morhuaENSGMOP0000005776995.588293.552
ENSG00000126070homo_sapiensENSP0000036228796.395392.907gadus_morhuaENSGMOP0000005606895.39791.9448
ENSG00000126070homo_sapiensENSP0000036228796.744293.7209fundulus_heteroclitusENSFHEP0000001454096.296393.287
ENSG00000126070homo_sapiensENSP0000036228725.697724.3023fundulus_heteroclitusENSFHEP0000001620087.698482.9365
ENSG00000126070homo_sapiensENSP0000036228719.534918.9535fundulus_heteroclitusENSFHEP0000001910376.363674.0909
ENSG00000126070homo_sapiensENSP0000036228798.372196.9767poecilia_reticulataENSPREP0000000972997.577996.1938
ENSG00000126070homo_sapiensENSP0000036228779.069876.6279poecilia_reticulataENSPREP0000001337497.841794.8201
ENSG00000126070homo_sapiensENSP0000036228797.441993.8372xiphophorus_maculatusENSXMAP0000004088397.78394.1657
ENSG00000126070homo_sapiensENSP0000036228798.372196.9767xiphophorus_maculatusENSXMAP0000000719097.577996.1938
ENSG00000126070homo_sapiensENSP0000036228791.162890.1163oryzias_latipesENSORLP0000001881899.11597.9772
ENSG00000126070homo_sapiensENSP0000036228796.627992.5581oryzias_latipesENSORLP0000001140396.627992.5581
ENSG00000126070homo_sapiensENSP0000036228796.511693.8372cyclopterus_lumpusENSCLMP0000504221493.468590.8784
ENSG00000126070homo_sapiensENSP0000036228797.90796.1628cyclopterus_lumpusENSCLMP0000503242095.790794.0842
ENSG00000126070homo_sapiensENSP000003622879592.4419oreochromis_niloticusENSONIP0000006978489.192186.7904
ENSG00000126070homo_sapiensENSP0000036228797.558195.4651oreochromis_niloticusENSONIP0000005980292.912590.9192
ENSG00000126070homo_sapiensENSP0000036228797.209394.7674haplochromis_burtoniENSHBUP0000003183796.424594.0023
ENSG00000126070homo_sapiensENSP0000036228788.953586.7442haplochromis_burtoniENSHBUP0000000897795.864793.4837
ENSG00000126070homo_sapiensENSP0000036228797.209394.7674astatotilapia_callipteraENSACLP0000000293696.424594.0023
ENSG00000126070homo_sapiensENSP0000036228798.488497.093astatotilapia_callipteraENSACLP0000000136398.488497.093
ENSG00000126070homo_sapiensENSP0000036228796.744294.8837sparus_aurataENSSAUP0001006923694.438192.622
ENSG00000126070homo_sapiensENSP0000036228797.790796.3953sparus_aurataENSSAUP0001005723996.44595.0688
ENSG00000126070homo_sapiensENSP0000036228797.325695.2326lates_calcariferENSLCAP0001003667591.375589.4105
ENSG00000126070homo_sapiensENSP0000036228797.90797.4419xenopus_tropicalisENSXETP0000011148096.338795.881
ENSG00000126070homo_sapiensENSP0000036228799.651299.5349chrysemys_picta_belliiENSCPBP0000002618799.651299.5349
ENSG00000126070homo_sapiensENSP0000036228798.720998.6047sphenodon_punctatusENSSPUP0000000102998.95198.8345
ENSG00000126070homo_sapiensENSP0000036228799.651299.5349crocodylus_porosusENSCPRP0000502601599.651299.5349
ENSG00000126070homo_sapiensENSP0000036228798.604798.0233laticauda_laticaudataENSLLTP0000001527397.583497.0081
ENSG00000126070homo_sapiensENSP0000036228798.023397.7907notechis_scutatusENSNSUP0000002765398.137497.9045
ENSG00000126070homo_sapiensENSP0000036228799.418699.186pseudonaja_textilisENSPTXP0000000262499.418699.186
ENSG00000126070homo_sapiensENSP0000036228799.651299.5349anas_platyrhynchos_platyrhynchosENSAPLP0000000944780.849180.7547
ENSG00000126070homo_sapiensENSP0000036228799.069898.9535gallus_gallusENSGALP0001002090098.839998.7239
ENSG00000126070homo_sapiensENSP0000036228795.930293.9535meleagris_gallopavoENSMGAP0000002243893.963692.0273
ENSG00000126070homo_sapiensENSP0000036228798.023397.7907serinus_canariaENSSCAP0000002140999.763399.5266
ENSG00000126070homo_sapiensENSP0000036228799.534999.3023parus_majorENSPMJP0000000823099.534999.3023
ENSG00000126070homo_sapiensENSP0000036228799.651299.186anolis_carolinensisENSACAP0000000344899.651299.186
ENSG00000126070homo_sapiensENSP000003622876.395356.04651neolamprologus_brichardiENSNBRP0000001411087.301682.5397
ENSG00000126070homo_sapiensENSP000003622876.395356.16279neolamprologus_brichardiENSNBRP0000002036684.615481.5385
ENSG00000126070homo_sapiensENSP0000036228790.116388.0233neolamprologus_brichardiENSNBRP0000002042297.977295.7016
ENSG00000126070homo_sapiensENSP0000036228783.953582.2093neolamprologus_brichardiENSNBRP0000001416397.567695.5405
ENSG00000126070homo_sapiensENSP0000036228799.302398.9535naja_najaENSNNAP0000000583697.697.2571
ENSG00000126070homo_sapiensENSP0000036228796.976796.6279podarcis_muralisENSPMRP0000001696395.642295.2982
ENSG00000126070homo_sapiensENSP0000036228798.023397.7907geospiza_fortisENSGFOP0000001919899.763399.5266
ENSG00000126070homo_sapiensENSP0000036228799.651299.4186taeniopygia_guttataENSTGUP0000001537299.651299.4186
ENSG00000126070homo_sapiensENSP0000036228798.372196.9767erpetoichthys_calabaricusENSECRP0000002254998.143996.7517
ENSG00000126070homo_sapiensENSP0000036228727.09325kryptolebias_marmoratusENSKMAP0000000552492.828785.6574
ENSG00000126070homo_sapiensENSP0000036228798.488497.093kryptolebias_marmoratusENSKMAP0000002637697.693296.3091
ENSG00000126070homo_sapiensENSP0000036228799.534999.186salvator_merianaeENSSMRP0000000091799.534999.186
ENSG00000126070homo_sapiensENSP0000036228795.581491.7442oryzias_javanicusENSOJAP0000001223094.919291.1085
ENSG00000126070homo_sapiensENSP0000036228791.162890amphilophus_citrinellusENSACIP0000000680599.11597.8508
ENSG00000126070homo_sapiensENSP000003622876.860476.39535amphilophus_citrinellusENSACIP0000000675785.507279.7101
ENSG00000126070homo_sapiensENSP000003622879088.1395amphilophus_citrinellusENSACIP0000002484897.850895.8281
ENSG00000126070homo_sapiensENSP000003622876.511636.16279amphilophus_citrinellusENSACIP0000002482588.888984.127
ENSG00000126070homo_sapiensENSP0000036228794.418692.093dicentrarchus_labraxENSDLAP0000506682591.544589.2897
ENSG00000126070homo_sapiensENSP0000036228798.255896.6279dicentrarchus_labraxENSDLAP0000500700773.478372.2609
ENSG00000126070homo_sapiensENSP0000036228798.488497.093amphiprion_perculaENSAPEP0000000614197.693296.3091
ENSG00000126070homo_sapiensENSP0000036228797.558195amphiprion_perculaENSAPEP0000002859196.770594.233
ENSG00000126070homo_sapiensENSP0000036228796.046591.8605oryzias_sinensisENSOSIP0000003964792.600988.565
ENSG00000126070homo_sapiensENSP0000036228794.883794.6512pelodiscus_sinensisENSPSIP0000000805099.270199.0268
ENSG00000126070homo_sapiensENSP0000036228799.651299.5349gopherus_evgoodeiENSGEVP0000500786999.651299.5349
ENSG00000126070homo_sapiensENSP0000036228799.302399.0698chelonoidis_abingdoniiENSCABP0000002056498.728398.4971
ENSG00000126070homo_sapiensENSP0000036228797.674495.6977seriola_dumeriliENSSDUP0000001109196.885894.925
ENSG00000126070homo_sapiensENSP0000036228798.488497.093seriola_dumeriliENSSDUP0000001494898.488497.093
ENSG00000126070homo_sapiensENSP0000036228796.627993.4884cottoperca_gobioENSCGOP0000004370392.745589.7321
ENSG00000126070homo_sapiensENSP0000036228796.627994.7674cottoperca_gobioENSCGOP0000003995694.539292.719
ENSG00000126070homo_sapiensENSP0000036228799.418699.186struthio_camelus_australisENSSCUP0000001848697.826197.5973
ENSG00000126070homo_sapiensENSP0000036228799.651299.5349anser_brachyrhynchusENSABRP0000002491099.651299.5349
ENSG00000126070homo_sapiensENSP0000036228795.116392.7907gasterosteus_aculeatusENSGACP0000000321697.964195.5689
ENSG00000126070homo_sapiensENSP0000036228791.046590.1163gasterosteus_aculeatusENSGACP0000001646298.243497.2396
ENSG00000126070homo_sapiensENSP0000036228787.325684.0698cynoglossus_semilaevisENSCSEP0000001525894.943191.4033
ENSG00000126070homo_sapiensENSP0000036228791.046589.5349cynoglossus_semilaevisENSCSEP0000000154198.988697.3451
ENSG00000126070homo_sapiensENSP000003622877.093026.62791cynoglossus_semilaevisENSCSEP0000000154684.722279.1667
ENSG00000126070homo_sapiensENSP0000036228797.09393.6047poecilia_formosaENSPFOP0000000690197.319393.8228
ENSG00000126070homo_sapiensENSP0000036228798.023396.5116myripristis_murdjanENSMMDP0000504845895.039593.5738
ENSG00000126070homo_sapiensENSP0000036228797.90795.814myripristis_murdjanENSMMDP0000503582797.453795.3704
ENSG00000126070homo_sapiensENSP0000036228796.279193.9535sander_luciopercaENSSLUP0000000335194.520592.2374
ENSG00000126070homo_sapiensENSP0000036228752.90752.907strigops_habroptilaENSSHBP00005020101100100
ENSG00000126070homo_sapiensENSP0000036228798.488497.093amphiprion_ocellarisENSAOCP0000002815998.488497.093
ENSG00000126070homo_sapiensENSP0000036228783.953581.6279amphiprion_ocellarisENSAOCP0000001251896.653393.9759
ENSG00000126070homo_sapiensENSP0000036228751.860549.6512amphiprion_ocellarisENSAOCP0000003110584.469780.8712
ENSG00000126070homo_sapiensENSP0000036228799.651299.5349terrapene_carolina_triunguisENSTMTP0000001242999.651299.5349
ENSG00000126070homo_sapiensENSP0000036228797.441996.0465hucho_huchoENSHHUP0000002388097.66996.2704
ENSG00000126070homo_sapiensENSP0000036228795.465193.2558hucho_huchoENSHHUP0000003576896.70294.4641
ENSG00000126070homo_sapiensENSP0000036228797.90796.0465hucho_huchoENSHHUP0000002126895.899894.0774
ENSG00000126070homo_sapiensENSP0000036228797.325695hucho_huchoENSHHUP0000006576796.87594.5602
ENSG00000126070homo_sapiensENSP0000036228796.860594.4186betta_splendensENSBSLP0000001154793.595591.236
ENSG00000126070homo_sapiensENSP0000036228798.255896.7442betta_splendensENSBSLP0000002975994.413492.9609
ENSG00000126070homo_sapiensENSP0000036228797.90795.4651pygocentrus_nattereriENSPNAP0000000242397.90795.4651
ENSG00000126070homo_sapiensENSP0000036228798.255896.6279pygocentrus_nattereriENSPNAP0000000122498.255896.6279
ENSG00000126070homo_sapiensENSP0000036228797.674494.7674anabas_testudineusENSATEP0000000740694.808191.9865
ENSG00000126070homo_sapiensENSP0000036228791.162890.1163seriola_lalandi_dorsalisENSSLDP0000000054599.11597.9772
ENSG00000126070homo_sapiensENSP000003622876.511636.04651seriola_lalandi_dorsalisENSSLDP0000000044784.848578.7879
ENSG00000126070homo_sapiensENSP0000036228797.674495.6977seriola_lalandi_dorsalisENSSLDP0000000868096.885894.925
ENSG00000126070homo_sapiensENSP0000036228790.930290labrus_bergyltaENSLBEP0000000985998.862297.8508
ENSG00000126070homo_sapiensENSP0000036228797.441995.814labrus_bergyltaENSLBEP0000002091995.444293.8497
ENSG00000126070homo_sapiensENSP000003622876.279075.93023labrus_bergyltaENSLBEP0000000988684.37579.6875
ENSG00000126070homo_sapiensENSP0000036228797.209394.8837pundamilia_nyerereiENSPNYP0000000615997.209394.8837
ENSG00000126070homo_sapiensENSP0000036228798.488496.9767pundamilia_nyerereiENSPNYP0000001655594.742793.2886
ENSG00000126070homo_sapiensENSP0000036228796.860594.0698mastacembelus_armatusENSMAMP0000006041094.874792.1412
ENSG00000126070homo_sapiensENSP0000036228798.488497.093stegastes_partitusENSSPAP0000002529997.693296.3091
ENSG00000126070homo_sapiensENSP0000036228797.90795.2326stegastes_partitusENSSPAP0000002091696.118793.4931
ENSG00000126070homo_sapiensENSP0000036228797.90796.1628oncorhynchus_tshawytschaENSOTSP0000502188496.44994.7308
ENSG00000126070homo_sapiensENSP0000036228797.674495.814oncorhynchus_tshawytschaENSOTSP0000501333494.808193.0023
ENSG00000126070homo_sapiensENSP0000036228798.372196.7442oncorhynchus_tshawytschaENSOTSP0000501123294.209492.6503
ENSG00000126070homo_sapiensENSP0000036228798.372196.7442oncorhynchus_tshawytschaENSOTSP0000506914394.209492.6503
ENSG00000126070homo_sapiensENSP0000036228798.488497.093acanthochromis_polyacanthusENSAPOP0000002066198.488497.093
ENSG00000126070homo_sapiensENSP0000036228798.023395.3488acanthochromis_polyacanthusENSAPOP0000001182297.231894.579
ENSG00000126070homo_sapiensENSP0000036228799.651299.5349aquila_chrysaetos_chrysaetosENSACCP0002001055699.651299.5349
ENSG00000126070homo_sapiensENSP0000036228787.209381.5116nothobranchius_furzeriENSNFUP0001504926766.964362.5893
ENSG00000126070homo_sapiensENSP0000036228798.255896.7442cyprinodon_variegatusENSCVAP0000002999098.255896.7442
ENSG00000126070homo_sapiensENSP0000036228748.837246.1628cyprinodon_variegatusENSCVAP0000000926790.712785.7451
ENSG00000126070homo_sapiensENSP0000036228727.790725.814cyprinodon_variegatusENSCVAP0000001456780.471474.7475
ENSG00000126070homo_sapiensENSP0000036228797.674494.8837denticeps_clupeoidesENSDCDP0000005212093.854891.1732
ENSG00000126070homo_sapiensENSP0000036228796.511694.6512larimichthys_croceaENSLCRP0000504677590.413988.671
ENSG00000126070homo_sapiensENSP0000036228797.90796.3953takifugu_rubripesENSTRUP0000006243596.559695.0688
ENSG00000126070homo_sapiensENSP0000036228796.279193.8372takifugu_rubripesENSTRUP0000006300993.665291.2896
ENSG00000126070homo_sapiensENSP0000036228796.860593.9535hippocampus_comesENSHCOP0000000938796.078493.1949
ENSG00000126070homo_sapiensENSP0000036228743.488442.907hippocampus_comesENSHCOP0000000423499.204297.878
ENSG00000126070homo_sapiensENSP0000036228785.581483.7209hippocampus_comesENSHCOP0000001996996.842194.7368
ENSG00000126070homo_sapiensENSP0000036228798.023396.6279cyprinus_carpio_carpioENSCCRP0000005380395.039593.6866
ENSG00000126070homo_sapiensENSP0000036228796.395393.9535cyprinus_carpio_carpioENSCCRP0000002892190.700288.4026
ENSG00000126070homo_sapiensENSP0000036228791.046590.2326cyprinus_carpio_carpioENSCCRP0000002977597.02696.1586
ENSG00000126070homo_sapiensENSP0000036228796.744294.186cyprinus_carpio_carpioENSCCRP0000003740093.483191.0112
ENSG00000126070homo_sapiensENSP0000036228799.534999.3023coturnix_japonicaENSCJPP0000502130599.534999.3023
ENSG00000126070homo_sapiensENSP0000036228798.372197.093poecilia_latipinnaENSPLAP0000000171697.577996.3091
ENSG00000126070homo_sapiensENSP0000036228787.09383.8372poecilia_latipinnaENSPLAP0000001383597.272793.6364
ENSG00000126070homo_sapiensENSP0000036228796.860594.3023sinocyclocheilus_grahamiENSSGRP0000006215995.292.6857
ENSG00000126070homo_sapiensENSP0000036228796.976795.4651sinocyclocheilus_grahamiENSSGRP0000010067692.666791.2222
ENSG00000126070homo_sapiensENSP0000036228797.90796.5116sinocyclocheilus_grahamiENSSGRP0000010597895.573294.2111
ENSG00000126070homo_sapiensENSP0000036228788.953586.2791sinocyclocheilus_grahamiENSSGRP0000010940394.444491.6049
ENSG00000126070homo_sapiensENSP0000036228798.488497.093maylandia_zebraENSMZEP0000501056598.488497.093
ENSG00000126070homo_sapiensENSP0000036228797.209394.8837maylandia_zebraENSMZEP0000503509296.424594.1176
ENSG00000126070homo_sapiensENSP0000036228795.930291.1628tetraodon_nigroviridisENSTNIP0000000518995.046190.3226
ENSG00000126070homo_sapiensENSP0000036228741.860538.8372tetraodon_nigroviridisENSTNIP0000001506575.471770.021
ENSG00000126070homo_sapiensENSP0000036228723.837222.7907tetraodon_nigroviridisENSTNIP0000000002196.698192.4528
ENSG00000126070homo_sapiensENSP0000036228726.279125tetraodon_nigroviridisENSTNIP0000000854491.49887.0445
ENSG00000126070homo_sapiensENSP000003622879.41869.06977tetraodon_nigroviridisENSTNIP0000000463093.103489.6552
ENSG00000126070homo_sapiensENSP0000036228727.325626.9767paramormyrops_kingsleyaeENSPKIP0000001230397.107495.8678
ENSG00000126070homo_sapiensENSP0000036228725.581424.7674paramormyrops_kingsleyaeENSPKIP0000001232391.286388.3817
ENSG00000126070homo_sapiensENSP0000036228797.558195.6977leptobrachium_leishanenseENSLLEP0000000378296.326194.4891
ENSG00000126070homo_sapiensENSP0000036228793.953591.3953scophthalmus_maximusENSSMAP0000003552991.093688.6133
ENSG00000126070homo_sapiensENSP0000036228796.744292.907oryzias_melastigmaENSOMEP0000003506493.799390.0789
ENSG00000126070homo_sapiensENSP0000036228791.162890oryzias_melastigmaENSOMEP0000001880899.11597.8508
ENSG00000126070homo_sapiensENSP000003622877.441866.62791oryzias_melastigmaENSOMEP0000001879476.190567.8571

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000794located_in condensed nuclear chromosome1IEAHomo_sapiens(9606)Component
GO:0000932located_in P-body1IEAHomo_sapiens(9606)Component
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0003725enables double-stranded RNA binding1IDAHomo_sapiens(9606)Function
GO:0003727enables single-stranded RNA binding2IBA,IDAHomo_sapiens(9606)Function
GO:0004521enables RNA endonuclease activity2IBA,IMPHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005654located_in nucleoplasm1IDAHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm1IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol2IDA,TASHomo_sapiens(9606)Component
GO:0006402involved_in mRNA catabolic process1IDAHomo_sapiens(9606)Process
GO:0010501involved_in RNA secondary structure unwinding2IDA,IMPHomo_sapiens(9606)Process
GO:0010628involved_in positive regulation of gene expression1IEAHomo_sapiens(9606)Process
GO:0016020located_in membrane1HDAHomo_sapiens(9606)Component
GO:0016442part_of RISC complex1IDAHomo_sapiens(9606)Component
GO:0031054involved_in pre-miRNA processing1IDAHomo_sapiens(9606)Process
GO:0035196involved_in miRNA processing1IMPHomo_sapiens(9606)Process
GO:0035198enables miRNA binding2IBA,IDAHomo_sapiens(9606)Function
GO:0035278involved_in miRNA-mediated gene silencing by inhibition of translation1IDAHomo_sapiens(9606)Process
GO:0035279NOT involved_in miRNA-mediated gene silencing by mRNA destabilization1IDAHomo_sapiens(9606)Process
GO:0036464located_in cytoplasmic ribonucleoprotein granule1IDAHomo_sapiens(9606)Component
GO:0046872enables metal ion binding1IEAHomo_sapiens(9606)Function
GO:0070578part_of RISC-loading complex1IDAHomo_sapiens(9606)Component
GO:0070922involved_in RISC complex assembly1IDAHomo_sapiens(9606)Process
GO:0072091involved_in regulation of stem cell proliferation1IMPHomo_sapiens(9606)Process
GO:0090624enables endoribonuclease activity, cleaving miRNA-paired mRNA1IMPHomo_sapiens(9606)Function
GO:0090625NOT involved_in siRNA-mediated gene silencing by mRNA destabilization1IDAHomo_sapiens(9606)Process
GO:1901224involved_in positive regulation of NIK/NF-kappaB signaling1IEAHomo_sapiens(9606)Process

Expression