RBPWorld - a comprehensive database of RNA Binding Proteins

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Functions and Diseases

RBP Type	Non-canonical_RBPs
Diseases	SARS-COV-2
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	N.A.
Localizations	Nucleoli
BulkPerturb-seq

Description

Ensembl ID	ENSG00000125821	Gene ID	92675	Accession	16219
Symbol	DTD1	Alias	DTD;DUEB;DUE-B;HARS2;pqn-68;C20orf88	Full Name	D-aminoacyl-tRNA deacylase 1
Status	Confidence	Length	178703 bases	Strand	Plus strand
Position	20 : 18587942 - 18766644	RNA binding domain	N.A.
Summary	The protein encoded by this gene is similar in sequence to histidyl-tRNA synthetase, which hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). The encoded protein binds the DNA unwinding element and plays a role in the initiation of DNA replication. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
DTD1-201	ENST00000377452	3953	209aa	ENSP00000366672
DTD1-203	ENST00000647441	4112	127aa	ENSP00000493969
DTD1-202	ENST00000494921	2890	213aa	ENSP00000495845

Gene Model

Click here to download ENSG00000125821's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID
27769	Blood Glucose	8.5860000E-005	-
37410	Platelet Function Tests	1.0640600E-005	-
37422	Platelet Function Tests	1.1356800E-005	-
39767	Platelet Function Tests	1.1669500E-005	-
41588	Platelet Function Tests	8.2951645E-006	-
103032	Sleep	5E-6	27126917

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000125821's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000049	enables tRNA binding	1	IEA	Homo_sapiens(9606)	Function
GO:0003677	enables DNA binding	1	EXP	Homo_sapiens(9606)	Function
GO:0005634	located_in nucleus	1	IEA	Homo_sapiens(9606)	Component
GO:0005737	is_active_in cytoplasm	1	IBA	Homo_sapiens(9606)	Component
GO:0006260	involved_in DNA replication	1	IEA	Homo_sapiens(9606)	Process
GO:0006399	involved_in tRNA metabolic process	1	IBA	Homo_sapiens(9606)	Process
GO:0032508	involved_in DNA duplex unwinding	1	EXP	Homo_sapiens(9606)	Process
GO:0046872	enables metal ion binding	1	IEA	Homo_sapiens(9606)	Function
GO:0051500	enables D-tyrosyl-tRNA(Tyr) deacylase activity	1	IBA	Homo_sapiens(9606)	Function
GO:0106074	involved_in aminoacyl-tRNA metabolism involved in translational fidelity	1	IEA	Homo_sapiens(9606)	Process

Expression