Functions and Diseases

RBP Type Canonical_RBPs
Diseases N.A.
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions E3 ligase
Localizations Nucleoli
BulkPerturb-seq

Description

Ensembl ID ENSG00000124900 Gene ID 84767 Accession 19023
Symbol TRIM51 Alias SPRYD5;TRIM51A Full Name tripartite motif-containing 51
Status Confidence Length 8514 bases Strand Plus strand
Position 11 : 55883297 - 55891810 RNA binding domain SPRY
Summary Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in innate immune response; protein ubiquitination; and regulation of gene expression. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000244891 SPRY PF00622 3.2e-07 1
ENSP00000395086 SPRY PF00622 6e-07 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
TRIM51-202 ENST00000449290 1629 452aa ENSP00000395086
TRIM51-201 ENST00000244891 1329 309aa ENSP00000244891

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
32810Body Mass Index9.6729887E-005-
32831Body Mass Index9.6577257E-005-
32832Body Mass Index9.6501072E-005-
32858Body Mass Index9.2052279E-005-
32859Body Mass Index9.1855646E-005-
32876Body Mass Index9.2175504E-005-

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0005737is_active_in cytoplasm1IBAHomo_sapiens(9606)Component
GO:0008270enables zinc ion binding1IEAHomo_sapiens(9606)Function
GO:0010468involved_in regulation of gene expression1IBAHomo_sapiens(9606)Process
GO:0016567involved_in protein ubiquitination1IBAHomo_sapiens(9606)Process
GO:0045087involved_in innate immune response1IBAHomo_sapiens(9606)Process
GO:0061630enables ubiquitin protein ligase activity1IBAHomo_sapiens(9606)Function

Expression