RBPWorld - a comprehensive database of RNA Binding Proteins

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Functions and Diseases

RBP Type	Non-canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Metabolic enzyme
Localizations	N.A.
BulkPerturb-seq

Description

Ensembl ID	ENSG00000124217	Gene ID	27304	Accession	15765
Symbol	MOCS3	Alias	UBA4	Full Name	molybdenum cofactor synthesis 3
Status	Confidence	Length	5112 bases	Strand	Plus strand
Position	20 : 50958818 - 50963929	RNA binding domain	N.A.
Summary	Molybdenum cofactor (MoCo) is necessary for the function of all molybdoenzymes. The protein encoded by this gene adenylates and activates molybdopterin synthase, an enzyme required for biosynthesis of MoCo. This gene contains no introns. A pseudogene of this gene is present on chromosome 14. [provided by RefSeq, Nov 2012]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal
36671528	The Human Mercaptopyruvate Sulfurtransferase TUM1 Is Involved in Moco Biosynthesis, Cytosolic tRNA Thiolation and Cellular Bioenergetics in Human Embryonic Kidney Cells.	Olalekan Moses Ogunkola	2023-01-10	Biomolecules

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
MOCS3-201	ENST00000244051	5112	460aa	ENSP00000244051

Gene Model

Click here to download ENSG00000124217's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID
69561	Plaque, Amyloid	7E-7	26268530

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000124217's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0002098	involved_in tRNA wobble uridine modification	1	IDA	Homo_sapiens(9606)	Process
GO:0002143	involved_in tRNA wobble position uridine thiolation	1	IBA	Homo_sapiens(9606)	Process
GO:0004792	enables thiosulfate sulfurtransferase activity	2	IBA,IMP	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005524	enables ATP binding	1	IEA	Homo_sapiens(9606)	Function
GO:0005737	is_active_in cytoplasm	1	IBA	Homo_sapiens(9606)	Component
GO:0005829	located_in cytosol	2	IDA,TAS	Homo_sapiens(9606)	Component
GO:0006777	involved_in Mo-molybdopterin cofactor biosynthetic process	1	IDA	Homo_sapiens(9606)	Process
GO:0016779	enables nucleotidyltransferase activity	2	IBA,IDA	Homo_sapiens(9606)	Function
GO:0016783	enables sulfurtransferase activity	1	IDA	Homo_sapiens(9606)	Function
GO:0032447	involved_in protein urmylation	1	IBA	Homo_sapiens(9606)	Process
GO:0034227	involved_in tRNA thio-modification	1	IDA	Homo_sapiens(9606)	Process
GO:0042292	enables URM1 activating enzyme activity	2	IBA,IDA	Homo_sapiens(9606)	Function
GO:0043545	involved_in molybdopterin cofactor metabolic process	1	IDA	Homo_sapiens(9606)	Process
GO:0046872	enables metal ion binding	1	IEA	Homo_sapiens(9606)	Function
GO:0061604	enables molybdopterin-synthase sulfurtransferase activity	1	IEA	Homo_sapiens(9606)	Function
GO:0061605	enables molybdopterin-synthase adenylyltransferase activity	1	IEA	Homo_sapiens(9606)	Function

Expression