RBPWorld - a comprehensive database of RNA Binding Proteins

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RBP World!

Functions and Diseases

RBP Type	Non-canonical_RBPs
Diseases	FlavivirusesSARS-COV-2
Drug	Drug
Main interacting RNAs	N.A.
Moonlighting functions	N.A.
Localizations	N.A.
BulkPerturb-seq

Description

Ensembl ID	ENSG00000123416	Gene ID	10376	Accession	18809
Symbol	TUBA1B	Alias	K-ALPHA-1	Full Name	tubulin alpha 1b
Status	Confidence	Length	3616 bases	Strand	Minus strand
Position	12 : 49127782 - 49131397	RNA binding domain	N.A.
Summary	Enables double-stranded RNA binding activity and ubiquitin protein ligase binding activity. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to act upstream of or within cellular response to interleukin-4. Located in microtubule. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
TUBA1B-202	ENST00000336023	1627	451aa	ENSP00000336799
TUBA1B-201	ENST00000332858	3198	No protein	-
TUBA1B-204	ENST00000547765	1875	49aa	ENSP00000448045
TUBA1B-206	ENST00000550367	835	246aa	ENSP00000449325
TUBA1B-207	ENST00000551324	840	No protein	-
TUBA1B-205	ENST00000549870	565	81aa	ENSP00000449460
TUBA1B-203	ENST00000547476	584	75aa	ENSP00000449748
TUBA1B-208	ENST00000552984	574	49aa	ENSP00000448648

Gene Model

Click here to download ENSG00000123416's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000123416's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000226	involved_in microtubule cytoskeleton organization	2	IBA,IDA	Homo_sapiens(9606)	Process
GO:0000278	involved_in mitotic cell cycle	1	IBA	Homo_sapiens(9606)	Process
GO:0003725	enables double-stranded RNA binding	1	IDA	Homo_sapiens(9606)	Function
GO:0003924	enables GTPase activity	1	IDA	Homo_sapiens(9606)	Function
GO:0005198	enables structural molecule activity	1	TAS	Homo_sapiens(9606)	Function
GO:0005200	enables structural constituent of cytoskeleton	2	IBA,IDA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005525	enables GTP binding	2	IBA,IDA	Homo_sapiens(9606)	Function
GO:0005737	is_active_in cytoplasm	1	IBA	Homo_sapiens(9606)	Component
GO:0005874	is_active_in microtubule	3	IBA,IDA,TAS	Homo_sapiens(9606)	Component
GO:0005881	located_in cytoplasmic microtubule	1	IEA	Homo_sapiens(9606)	Component
GO:0007017	involved_in microtubule-based process	1	TAS	Homo_sapiens(9606)	Process
GO:0015630	is_active_in microtubule cytoskeleton	2	IDA	Homo_sapiens(9606)	Component
GO:0030705	involved_in cytoskeleton-dependent intracellular transport	1	TAS	Homo_sapiens(9606)	Process
GO:0031625	enables ubiquitin protein ligase binding	1	IPI	Homo_sapiens(9606)	Function
GO:0051301	involved_in cell division	1	TAS	Homo_sapiens(9606)	Process
GO:0071353	involved_in cellular response to interleukin-4	1	IEA	Homo_sapiens(9606)	Process

Expression