Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq DataSet_01_240

Description

Ensembl ID ENSG00000122729 Gene ID 48 Accession 117
Symbol ACO1 Alias IRP1;ACONS;HEL60;IREB1;IREBP;IREBP1 Full Name aconitase 1
Status Confidence Length 70167 bases Strand Plus strand
Position 9 : 32384603 - 32454769 RNA binding domain Aconitase , Aconitase_C
Summary The protein encoded by this gene is a bifunctional, cytosolic protein that functions as an essential enzyme in the TCA cycle and interacts with mRNA to control the levels of iron inside cells. When cellular iron levels are high, this protein binds to a 4Fe-4S cluster and functions as an aconitase. Aconitases are iron-sulfur proteins that function to catalyze the conversion of citrate to isocitrate. When cellular iron levels are low, the protein binds to iron-responsive elements (IREs), which are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. When the protein binds to IRE, it results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degraded transferrin receptor mRNA. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Alternative splicing results in multiple transcript variants [provided by RefSeq, Jan 2014]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000309477 Aconitase_C PF00694 4.7e-42 1
ENSP00000309477 Aconitase PF00330 6.5e-174 2
ENSP00000369255 Aconitase_C PF00694 4.7e-42 1
ENSP00000369255 Aconitase PF00330 6.5e-174 2
ENSP00000438733 Aconitase_C PF00694 4.7e-42 1
ENSP00000438733 Aconitase PF00330 6.5e-174 2

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
ACO1-203 ENST00000541043 3618 889aa ENSP00000438733
ACO1-202 ENST00000379923 3601 889aa ENSP00000369255
ACO1-201 ENST00000309951 7443 889aa ENSP00000309477

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
13893Myocardial Infarction3.8807257E-004-
13916Myocardial Infarction4.3904345E-004-
13960Myocardial Infarction3.7377826E-005-
15530Heart Failure4.3032748E-004-
25644Coronary Artery Disease4.6210000E-005-
67907Psoriasis4E-925574825
80358Asthma4E-622561531
95391Immunoglobulins5E-623382691

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000122729homo_sapiensENSP0000021625446.666729.359homo_sapiensENSP0000030947740.944925.7593
ENSG00000122729homo_sapiensENSP0000025888673.520256.4901homo_sapiensENSP0000030947779.6461.1924

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000122729homo_sapiensENSP0000030947799.325198.9876nomascus_leucogenysENSNLEP0000000421399.325198.9876
ENSG00000122729homo_sapiensENSP0000030947710099.8875pan_paniscusENSPPAP0000002064810099.8875
ENSG00000122729homo_sapiensENSP0000030947799.77599.1001pongo_abeliiENSPPYP0000002145699.77599.1001
ENSG00000122729homo_sapiensENSP0000030947710099.8875pan_troglodytesENSPTRP0000003564610099.8875
ENSG00000122729homo_sapiensENSP0000030947799.887599.775gorilla_gorillaENSGGOP0000001593099.887599.775
ENSG00000122729homo_sapiensENSP0000030947795.163190.4387ornithorhynchus_anatinusENSOANP0000001921595.163190.4387
ENSG00000122729homo_sapiensENSP0000030947795.950590.2137sarcophilus_harrisiiENSSHAP0000001033595.520789.8096
ENSG00000122729homo_sapiensENSP0000030947774.915671.5411notamacropus_eugeniiENSMEUP000000134787571.6216
ENSG00000122729homo_sapiensENSP0000030947768.05465.6918choloepus_hoffmanniENSCHOP0000000796968.05465.6918
ENSG00000122729homo_sapiensENSP0000030947797.187994.2632dasypus_novemcinctusENSDNOP0000000304897.187994.2632
ENSG00000122729homo_sapiensENSP0000030947784.926982.4522erinaceus_europaeusENSEEUP0000001386384.926982.4522
ENSG00000122729homo_sapiensENSP0000030947760.854958.6052echinops_telfairiENSETEP0000001006462.833960.511
ENSG00000122729homo_sapiensENSP0000030947798.650297.0754callithrix_jacchusENSCJAP0000001432283.923482.5837
ENSG00000122729homo_sapiensENSP0000030947799.325198.4252cercocebus_atysENSCATP0000004597799.325198.4252
ENSG00000122729homo_sapiensENSP0000030947799.550198.8751macaca_fascicularisENSMFAP0000000396798.333397.6667
ENSG00000122729homo_sapiensENSP0000030947799.550198.9876macaca_mulattaENSMMUP0000007948799.550198.9876
ENSG00000122729homo_sapiensENSP0000030947799.550198.7627macaca_nemestrinaENSMNEP0000004497299.550198.7627
ENSG00000122729homo_sapiensENSP0000030947797.300395.9505papio_anubisENSPANP0000006081890.575989.3194
ENSG00000122729homo_sapiensENSP0000030947799.550198.7627mandrillus_leucophaeusENSMLEP0000000145699.550198.7627
ENSG00000122729homo_sapiensENSP0000030947797.750394.8256tursiops_truncatusENSTTRP0000001610897.421594.5067
ENSG00000122729homo_sapiensENSP0000030947795.950592.2385vulpes_vulpesENSVVUP0000002893286.511283.1643
ENSG00000122729homo_sapiensENSP0000030947797.862893.4758mus_spretusMGP_SPRETEiJ_P006420297.862893.4758
ENSG00000122729homo_sapiensENSP0000030947797.975395.3881equus_asinusENSEASP0000505064391.974789.5459
ENSG00000122729homo_sapiensENSP0000030947797.525394.0382capra_hircusENSCHIP0000000352696.333392.8889
ENSG00000122729homo_sapiensENSP0000030947795.83892.6884loxodonta_africanaENSLAFP0000001913694.77291.6574
ENSG00000122729homo_sapiensENSP0000030947797.300393.9258panthera_leoENSPLOP0000002629697.300393.9258
ENSG00000122729homo_sapiensENSP0000030947797.187993.3633ailuropoda_melanoleucaENSAMEP0000000396297.187993.3633
ENSG00000122729homo_sapiensENSP0000030947797.637894.3757bos_indicus_hybridENSBIXP0000504343896.551793.3259
ENSG00000122729homo_sapiensENSP0000030947797.412893.9258oryctolagus_cuniculusENSOCUP0000004209280.185277.3148
ENSG00000122729homo_sapiensENSP0000030947797.975395.2756equus_caballusENSECAP0000007751886.580584.1948
ENSG00000122729homo_sapiensENSP0000030947795.950592.2385canis_lupus_familiarisENSCAFP0084502661386.511283.1643
ENSG00000122729homo_sapiensENSP0000030947797.300393.9258panthera_pardusENSPPRP0000001811797.300393.9258
ENSG00000122729homo_sapiensENSP0000030947797.525394.6007marmota_marmota_marmotaENSMMMP0000001001297.415794.4944
ENSG00000122729homo_sapiensENSP0000030947797.862894.6007balaenoptera_musculusENSBMSP0001000273897.862894.6007
ENSG00000122729homo_sapiensENSP0000030947796.175592.9134cavia_porcellusENSCPOP0000000340396.175592.9134
ENSG00000122729homo_sapiensENSP0000030947797.300394.0382felis_catusENSFCAP0000004806697.300394.0382
ENSG00000122729homo_sapiensENSP0000030947797.075493.7008ursus_americanusENSUAMP0000002675497.075493.7008
ENSG00000122729homo_sapiensENSP0000030947795.725591.0011monodelphis_domesticaENSMODP0000005950193.107288.512
ENSG00000122729homo_sapiensENSP0000030947797.412894.1507bison_bison_bisonENSBBBP0000002609197.412894.1507
ENSG00000122729homo_sapiensENSP0000030947797.862894.7132monodon_monocerosENSMMNP0001502762997.862894.7132
ENSG00000122729homo_sapiensENSP0000030947797.862895.0506sus_scrofaENSSSCP0000005879897.862895.0506
ENSG00000122729homo_sapiensENSP0000030947797.975395.0506microcebus_murinusENSMICP0000001854394.366291.5493
ENSG00000122729homo_sapiensENSP0000030947792.913489.3138octodon_degusENSODEP0000002093995.712692.0046
ENSG00000122729homo_sapiensENSP0000030947795.163191.901octodon_degusENSODEP0000000157897.129793.8002
ENSG00000122729homo_sapiensENSP0000030947797.975394.2632jaculus_jaculusENSJJAP0000001016497.975394.2632
ENSG00000122729homo_sapiensENSP0000030947797.525394.0382ovis_aries_rambouilletENSOARP0002001178496.333392.8889
ENSG00000122729homo_sapiensENSP0000030947797.075493.7008ursus_maritimusENSUMAP0000000751097.075493.7008
ENSG00000122729homo_sapiensENSP0000030947792.913489.8763ochotona_princepsENSOPRP0000001534192.913489.8763
ENSG00000122729homo_sapiensENSP0000030947797.862894.8256delphinapterus_leucasENSDLEP0000002913897.862894.8256
ENSG00000122729homo_sapiensENSP0000030947798.200294.9381physeter_catodonENSPCTP0000500085498.200294.9381
ENSG00000122729homo_sapiensENSP0000030947797.862893.8133mus_caroliMGP_CAROLIEiJ_P006177097.862893.8133
ENSG00000122729homo_sapiensENSP0000030947797.637893.3633mus_musculusENSMUSP0000010003897.637893.3633
ENSG00000122729homo_sapiensENSP0000030947796.737993.9258dipodomys_ordiiENSDORP0000001339796.737993.9258
ENSG00000122729homo_sapiensENSP0000030947797.187993.7008mustela_putorius_furoENSMPUP0000000430797.187993.7008
ENSG00000122729homo_sapiensENSP0000030947798.537796.5129aotus_nancymaaeENSANAP0000000048898.537796.5129
ENSG00000122729homo_sapiensENSP0000030947798.875197.0754saimiri_boliviensis_boliviensisENSSBOP0000001878298.875197.0754
ENSG00000122729homo_sapiensENSP0000030947793.588390.4387vicugna_pacosENSVPAP0000000919297.882494.5882
ENSG00000122729homo_sapiensENSP0000030947799.325198.3127chlorocebus_sabaeusENSCSAP0000000606698.659297.6536
ENSG00000122729homo_sapiensENSP0000030947793.475891.1136tupaia_belangeriENSTBEP0000001073193.581191.2162
ENSG00000122729homo_sapiensENSP0000030947797.637894.0382mesocricetus_auratusENSMAUP0000002461297.637894.0382
ENSG00000122729homo_sapiensENSP0000030947797.975394.9381phocoena_sinusENSPSNP0000000280397.975394.9381
ENSG00000122729homo_sapiensENSP0000030947797.862894.7132camelus_dromedariusENSCDRP0000500945197.862894.7132
ENSG00000122729homo_sapiensENSP0000030947797.750396.063carlito_syrichtaENSTSYP0000000383597.203695.5257
ENSG00000122729homo_sapiensENSP0000030947797.187993.8133panthera_tigris_altaicaENSPTIP0000001850095.681192.3588
ENSG00000122729homo_sapiensENSP0000030947797.187992.351rattus_norvegicusENSRNOP0000007863697.187992.351
ENSG00000122729homo_sapiensENSP0000030947797.637894.2632prolemur_simusENSPSMP0000001560497.200493.841
ENSG00000122729homo_sapiensENSP0000030947797.412894.0382microtus_ochrogasterENSMOCP0000001651997.412894.0382
ENSG00000122729homo_sapiensENSP0000030947790.326286.7267sorex_araneusENSSARP0000000762493.808490.0701
ENSG00000122729homo_sapiensENSP0000030947798.087794.1507peromyscus_maniculatus_bairdiiENSPEMP0000002055298.087794.1507
ENSG00000122729homo_sapiensENSP0000030947797.525394.2632bos_mutusENSBMUP0000002408096.440593.2147
ENSG00000122729homo_sapiensENSP0000030947797.975393.7008mus_spicilegusENSMSIP0000002948897.975393.7008
ENSG00000122729homo_sapiensENSP0000030947797.862894.6007cricetulus_griseus_chok1gshdENSCGRP0000102728997.862894.6007
ENSG00000122729homo_sapiensENSP0000030947787.73984.5894pteropus_vampyrusENSPVAP0000000224091.121587.8505
ENSG00000122729homo_sapiensENSP0000030947795.725593.0259myotis_lucifugusENSMLUP0000000275596.158293.4463
ENSG00000122729homo_sapiensENSP0000030947796.06391.2261vombatus_ursinusENSVURP0001000816296.06391.2261
ENSG00000122729homo_sapiensENSP0000030947797.525394.8256rhinolophus_ferrumequinumENSRFEP0001002854597.525394.8256
ENSG00000122729homo_sapiensENSP0000030947797.187993.7008neovison_visonENSNVIP0000000087397.187993.7008
ENSG00000122729homo_sapiensENSP0000030947797.525394.2632bos_taurusENSBTAP0000007063696.655593.4225
ENSG00000122729homo_sapiensENSP0000030947797.975394.6007heterocephalus_glaber_femaleENSHGLP0000002660497.975394.6007
ENSG00000122729homo_sapiensENSP0000030947799.325198.4252rhinopithecus_bietiENSRBIP0000002122199.325198.4252
ENSG00000122729homo_sapiensENSP0000030947795.950592.2385canis_lupus_dingoENSCAFP0002001819894.672691.01
ENSG00000122729homo_sapiensENSP0000030947797.187994.7132sciurus_vulgarisENSSVLP0000502055897.187994.7132
ENSG00000122729homo_sapiensENSP0000030947795.61389.6513phascolarctos_cinereusENSPCIP0000004005795.61389.6513
ENSG00000122729homo_sapiensENSP0000030947772.21669.5163procavia_capensisENSPCAP0000001237585.25982.0717
ENSG00000122729homo_sapiensENSP0000030947797.975394.8256nannospalax_galiliENSNGAP0000000435997.975394.8256
ENSG00000122729homo_sapiensENSP0000030947797.525394.2632bos_grunniensENSBGRP0000000202497.525394.2632
ENSG00000122729homo_sapiensENSP0000030947796.625492.2385chinchilla_lanigeraENSCLAP0000000348096.625492.2385
ENSG00000122729homo_sapiensENSP0000030947771.76668.5039cervus_hanglu_yarkandensisENSCHYP0000003093195.795891.4414
ENSG00000122729homo_sapiensENSP0000030947797.412894.0382catagonus_wagneriENSCWAP0000002393096.436593.0958
ENSG00000122729homo_sapiensENSP0000030947797.525395.0506ictidomys_tridecemlineatusENSSTOP0000000623496.979994.519
ENSG00000122729homo_sapiensENSP0000030947797.750394.9381otolemur_garnettiiENSOGAP0000000942497.750394.9381
ENSG00000122729homo_sapiensENSP0000030947798.650296.6254cebus_imitatorENSCCAP0000000944798.650296.6254
ENSG00000122729homo_sapiensENSP0000030947797.525394.8256urocitellus_parryiiENSUPAP0001000976796.979994.2953
ENSG00000122729homo_sapiensENSP0000030947797.412894.0382moschus_moschiferusENSMMSP0000002602997.412894.0382
ENSG00000122729homo_sapiensENSP0000030947799.325198.5377rhinopithecus_roxellanaENSRROP0000003859897.785297.01
ENSG00000122729homo_sapiensENSP0000030947797.862893.7008mus_pahariMGP_PahariEiJ_P005743397.862893.7008
ENSG00000122729homo_sapiensENSP0000030947787.289184.5894propithecus_coquereliENSPCOP0000001860098.227995.1899
ENSG00000122729homo_sapiensENSP0000030947785.714375.3656petromyzon_marinusENSPMAP0000000153785.234974.9441
ENSG00000122729homo_sapiensENSP0000030947785.601870.6412petromyzon_marinusENSPMAP0000000240584.181469.469
ENSG00000122729homo_sapiensENSP0000030947779.302662.3172eptatretus_burgeriENSEBUP0000002501372.307756.8205
ENSG00000122729homo_sapiensENSP0000030947786.276777.9528callorhinchus_miliiENSCMIP0000002682185.698377.4302
ENSG00000122729homo_sapiensENSP0000030947762.429755.793latimeria_chalumnaeENSLACP0000000104682.466673.6999
ENSG00000122729homo_sapiensENSP0000030947792.013584.252lepisosteus_oculatusENSLOCP0000001361491.910184.1573
ENSG00000122729homo_sapiensENSP0000030947790.663781.2149clupea_harengusENSCHAP0000002518388.087478.9071
ENSG00000122729homo_sapiensENSP0000030947792.238582.3397danio_rerioENSDARP0000004525292.134882.2472
ENSG00000122729homo_sapiensENSP0000030947792.013582.0023carassius_auratusENSCARP0000005170889.009879.3254
ENSG00000122729homo_sapiensENSP0000030947792.12681.7773astyanax_mexicanusENSAMXP0000000256959.737453.027
ENSG00000122729homo_sapiensENSP0000030947789.201379.1901ictalurus_punctatusENSIPUP0000002976288.901378.9238
ENSG00000122729homo_sapiensENSP0000030947789.876380.4274esox_luciusENSELUP0000004698385.821776.7991
ENSG00000122729homo_sapiensENSP0000030947791.001182.0023electrophorus_electricusENSEEEP0000003882587.64978.9816
ENSG00000122729homo_sapiensENSP0000030947791.226182.4522oncorhynchus_kisutchENSOKIP0000500789289.811781.1739
ENSG00000122729homo_sapiensENSP0000030947791.451182.7896oncorhynchus_mykissENSOMYP0000010191289.834381.326
ENSG00000122729homo_sapiensENSP0000030947790.213781.3273salmo_salarENSSSAP0000007065189.809680.963
ENSG00000122729homo_sapiensENSP0000030947773.115963.667salmo_salarENSSSAP0000007850478.883568.6893
ENSG00000122729homo_sapiensENSP0000030947760.1851.856salmo_truttaENSSTUP0000000338580.572369.4277
ENSG00000122729homo_sapiensENSP0000030947791.338682.4522salmo_truttaENSSTUP0000009221189.922581.1739
ENSG00000122729homo_sapiensENSP0000030947789.201378.8526gadus_morhuaENSGMOP0000005422883.649873.9451
ENSG00000122729homo_sapiensENSP0000030947790.888682.3397fundulus_heteroclitusENSFHEP0000000470190.380381.8792
ENSG00000122729homo_sapiensENSP0000030947791.226181.1024poecilia_reticulataENSPREP0000003217490.715980.6488
ENSG00000122729homo_sapiensENSP0000030947791.001181.3273xiphophorus_maculatusENSXMAP0000002118290.492280.8725
ENSG00000122729homo_sapiensENSP0000030947790.326281.6648oryzias_latipesENSORLP0000002559090.224781.573
ENSG00000122729homo_sapiensENSP0000030947789.988879.7525cyclopterus_lumpusENSCLMP0000500991186.580176.7316
ENSG00000122729homo_sapiensENSP0000030947791.451181.8898haplochromis_burtoniENSHBUP0000000741190.939681.4318
ENSG00000122729homo_sapiensENSP0000030947791.338681.7773astatotilapia_callipteraENSACLP0000001133690.827781.3199
ENSG00000122729homo_sapiensENSP0000030947791.226182.2272sparus_aurataENSSAUP0001001124789.120980.3297
ENSG00000122729homo_sapiensENSP0000030947791.001181.8898lates_calcariferENSLCAP0001004686487.839379.0445
ENSG00000122729homo_sapiensENSP0000030947793.588385.3768xenopus_tropicalisENSXETP0000007074890.730682.7699
ENSG00000122729homo_sapiensENSP0000030947794.938188.5264chrysemys_picta_belliiENSCPBP0000001052294.938188.5264
ENSG00000122729homo_sapiensENSP0000030947792.688486.3892sphenodon_punctatusENSSPUP0000000385193.849787.4715
ENSG00000122729homo_sapiensENSP0000030947792.35185.2643crocodylus_porosusENSCPRP0000502210791.834484.7875
ENSG00000122729homo_sapiensENSP0000030947793.925886.9516laticauda_laticaudataENSLLTP0000002290493.925886.9516
ENSG00000122729homo_sapiensENSP0000030947794.150786.8391notechis_scutatusENSNSUP0000000948594.044986.7416
ENSG00000122729homo_sapiensENSP0000030947794.038287.0641pseudonaja_textilisENSPTXP0000002115394.038287.0641
ENSG00000122729homo_sapiensENSP0000030947793.475887.6265anas_platyrhynchos_platyrhynchosENSAPLP0000001541993.475887.6265
ENSG00000122729homo_sapiensENSP0000030947793.813387.5141gallus_gallusENSGALP0001001336391.04884.9345
ENSG00000122729homo_sapiensENSP0000030947793.700887.0641meleagris_gallopavoENSMGAP0000002474089.569983.2258
ENSG00000122729homo_sapiensENSP0000030947793.363386.8391serinus_canariaENSSCAP0000001755793.363386.8391
ENSG00000122729homo_sapiensENSP0000030947793.700887.0641parus_majorENSPMJP0000000490893.700887.0641
ENSG00000122729homo_sapiensENSP0000030947786.164279.4151anolis_carolinensisENSACAP0000000184792.178184.9579
ENSG00000122729homo_sapiensENSP0000030947775.70365.3543neolamprologus_brichardiENSNBRP0000001155285.841874.1071
ENSG00000122729homo_sapiensENSP0000030947790.888684.1395naja_najaENSNNAP0000001858091.402784.6154
ENSG00000122729homo_sapiensENSP0000030947793.250886.2767podarcis_muralisENSPMRP0000003293393.566686.5688
ENSG00000122729homo_sapiensENSP0000030947793.363386.8391geospiza_fortisENSGFOP0000001334993.363386.8391
ENSG00000122729homo_sapiensENSP0000030947793.588386.8391taeniopygia_guttataENSTGUP0000000155993.588386.8391
ENSG00000122729homo_sapiensENSP0000030947792.463483.3521erpetoichthys_calabaricusENSECRP0000001177189.73880.8952
ENSG00000122729homo_sapiensENSP0000030947791.67680.9899kryptolebias_marmoratusENSKMAP0000002126291.163380.5369
ENSG00000122729homo_sapiensENSP0000030947794.600787.739salvator_merianaeENSSMRP0000002710494.600787.739
ENSG00000122729homo_sapiensENSP0000030947790.101280.5399oryzias_javanicusENSOJAP0000000456187.350178.0807
ENSG00000122729homo_sapiensENSP0000030947791.90182.3397amphilophus_citrinellusENSACIP0000001845191.38781.8792
ENSG00000122729homo_sapiensENSP0000030947792.12683.2396dicentrarchus_labraxENSDLAP0000501468790.397481.6777
ENSG00000122729homo_sapiensENSP0000030947791.788582.1147amphiprion_perculaENSAPEP0000002016691.275281.6555
ENSG00000122729homo_sapiensENSP0000030947794.600788.3015pelodiscus_sinensisENSPSIP0000000915594.600788.3015
ENSG00000122729homo_sapiensENSP0000030947794.825687.964gopherus_evgoodeiENSGEVP0000501533794.825687.964
ENSG00000122729homo_sapiensENSP0000030947794.825687.739chelonoidis_abingdoniiENSCABP0000000454794.825687.739
ENSG00000122729homo_sapiensENSP0000030947792.12682.6772seriola_dumeriliENSSDUP0000000401291.610782.2148
ENSG00000122729homo_sapiensENSP0000030947789.651380.315cottoperca_gobioENSCGOP0000005651586.162277.1892
ENSG00000122729homo_sapiensENSP0000030947794.038287.2891struthio_camelus_australisENSSCUP0000002141890.968484.4396
ENSG00000122729homo_sapiensENSP0000030947793.588387.2891anser_brachyrhynchusENSABRP0000000726989.366383.3512
ENSG00000122729homo_sapiensENSP0000030947790.776281.3273gasterosteus_aculeatusENSGACP0000000219790.268580.8725
ENSG00000122729homo_sapiensENSP0000030947788.638978.0652cynoglossus_semilaevisENSCSEP0000002854389.954379.2237
ENSG00000122729homo_sapiensENSP0000030947784.476975.703poecilia_formosaENSPFOP0000001357590.04880.6954
ENSG00000122729homo_sapiensENSP0000030947790.438781.3273myripristis_murdjanENSMMDP0000502767485.44176.8332
ENSG00000122729homo_sapiensENSP0000030947791.451182.1147sander_luciopercaENSSLUP0000003950890.233181.0211
ENSG00000122729homo_sapiensENSP0000030947793.588387.5141strigops_habroptilaENSSHBP0000502313793.588387.5141
ENSG00000122729homo_sapiensENSP0000030947791.788582.0023amphiprion_ocellarisENSAOCP0000002227091.275281.5436
ENSG00000122729homo_sapiensENSP0000030947794.938188.4139terrapene_carolina_triunguisENSTMTP0000001681194.938188.4139
ENSG00000122729homo_sapiensENSP0000030947794.263287.8515terrapene_carolina_triunguisENSTMTP0000002539889.148983.0851
ENSG00000122729homo_sapiensENSP0000030947791.226182.9021hucho_huchoENSHHUP0000001612087.770679.7619
ENSG00000122729homo_sapiensENSP0000030947791.563682.2272betta_splendensENSBSLP0000001644088.382279.3702
ENSG00000122729homo_sapiensENSP0000030947791.788583.0146pygocentrus_nattereriENSPNAP0000001214291.788583.0146
ENSG00000122729homo_sapiensENSP0000030947791.113682.2272anabas_testudineusENSATEP000000400679081.2222
ENSG00000122729homo_sapiensENSP0000030947792.238582.7896seriola_lalandi_dorsalisENSSLDP0000001770891.722682.3266
ENSG00000122729homo_sapiensENSP0000030947787.176678.2902labrus_bergyltaENSLBEP0000001804588.068279.0909
ENSG00000122729homo_sapiensENSP0000030947791.451181.8898pundamilia_nyerereiENSPNYP0000001244990.939681.4318
ENSG00000122729homo_sapiensENSP0000030947792.575983.0146mastacembelus_armatusENSMAMP0000000435391.955382.4581
ENSG00000122729homo_sapiensENSP0000030947792.12682.3397stegastes_partitusENSSPAP0000002536291.610781.8792
ENSG00000122729homo_sapiensENSP0000030947789.538880.6524oncorhynchus_tshawytschaENSOTSP0000510463784.411576.0339
ENSG00000122729homo_sapiensENSP0000030947791.451182.0023acanthochromis_polyacanthusENSAPOP0000002552390.939681.5436
ENSG00000122729homo_sapiensENSP0000030947793.475887.0641aquila_chrysaetos_chrysaetosENSACCP0002001901693.475887.0641
ENSG00000122729homo_sapiensENSP0000030947782.789673.3408nothobranchius_furzeriENSNFUP0001503568686.997677.0686
ENSG00000122729homo_sapiensENSP0000030947786.164276.4904cyprinodon_variegatusENSCVAP0000001715489.381679.3466
ENSG00000122729homo_sapiensENSP0000030947791.338682.2272denticeps_clupeoidesENSDCDP0000004789086.38377.766
ENSG00000122729homo_sapiensENSP0000030947791.113681.6648larimichthys_croceaENSLCRP0000504300388.524679.3443
ENSG00000122729homo_sapiensENSP0000030947793.588387.0641ficedula_albicollisENSFALP0000000121293.588387.0641
ENSG00000122729homo_sapiensENSP0000030947790.551278.8526hippocampus_comesENSHCOP0000002560290.044778.4116
ENSG00000122729homo_sapiensENSP0000030947792.35182.4522cyprinus_carpio_carpioENSCCRP0000003066189.824980.1969
ENSG00000122729homo_sapiensENSP0000030947793.363387.1766coturnix_japonicaENSCJPP0000500360690.809684.7921
ENSG00000122729homo_sapiensENSP0000030947784.926975.0281poecilia_latipinnaENSPLAP0000001837086.781676.6667
ENSG00000122729homo_sapiensENSP0000030947792.12682.1147sinocyclocheilus_grahamiENSSGRP0000005007489.021779.3478
ENSG00000122729homo_sapiensENSP0000030947792.463482.6772sinocyclocheilus_grahamiENSSGRP0000005791889.934480.4158
ENSG00000122729homo_sapiensENSP0000030947787.96478.7402maylandia_zebraENSMZEP0000501697189.781980.3674
ENSG00000122729homo_sapiensENSP0000030947790.101279.3026tetraodon_nigroviridisENSTNIP000000079679079.2135
ENSG00000122729homo_sapiensENSP0000030947790.776280.8774paramormyrops_kingsleyaeENSPKIP0000000717990.268580.4251
ENSG00000122729homo_sapiensENSP0000030947790.551281.6648scleropages_formosusENSSFOP0001507366886.559178.0645
ENSG00000122729homo_sapiensENSP0000030947793.475884.5894leptobrachium_leishanenseENSLLEP0000000385693.057184.2105
ENSG00000122729homo_sapiensENSP0000030947787.73977.5028scophthalmus_maximusENSSMAP0000004626382.802673.1423
ENSG00000122729homo_sapiensENSP0000030947790.101279.9775oryzias_melastigmaENSOMEP0000002601589.798279.7085

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003723enables RNA binding2IDA,NASHomo_sapiens(9606)Function
GO:0003994enables aconitate hydratase activity3IBA,IDA,IMPHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005737located_in cytoplasm2IMP,NASHomo_sapiens(9606)Component
GO:0005739is_active_in mitochondrion2IBA,IDAHomo_sapiens(9606)Component
GO:0005783located_in endoplasmic reticulum1IDAHomo_sapiens(9606)Component
GO:0005794located_in Golgi apparatus1IDAHomo_sapiens(9606)Component
GO:0005829is_active_in cytosol3IBA,IDA,TASHomo_sapiens(9606)Component
GO:0006099involved_in tricarboxylic acid cycle1IBAHomo_sapiens(9606)Process
GO:0006101involved_in citrate metabolic process3IBA,IDA,IMPHomo_sapiens(9606)Process
GO:0006417involved_in regulation of translation1IEAHomo_sapiens(9606)Process
GO:0006879involved_in intracellular iron ion homeostasis1IEAHomo_sapiens(9606)Process
GO:0009791involved_in post-embryonic development1IEAHomo_sapiens(9606)Process
GO:0010040involved_in response to iron(II) ion1IDAHomo_sapiens(9606)Process
GO:0030350enables iron-responsive element binding3IBA,IDA,IMPHomo_sapiens(9606)Function
GO:0046872enables metal ion binding1IEAHomo_sapiens(9606)Function
GO:0047780enables citrate dehydratase activity1IEAHomo_sapiens(9606)Function
GO:0050892involved_in intestinal absorption1IEAHomo_sapiens(9606)Process
GO:0051538enables 3 iron, 4 sulfur cluster binding2IBA,IMPHomo_sapiens(9606)Function
GO:0051539enables 4 iron, 4 sulfur cluster binding3IBA,IDA,IMPHomo_sapiens(9606)Function
GO:0070062located_in extracellular exosome1HDAHomo_sapiens(9606)Component

Expression