Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerSARS-COV-OC43FlavivirusesSARS-COV-2DengueZika
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq DataSet_01_220 DataSet_01_388 DataSet_02_23

Description

Ensembl ID ENSG00000121774 Gene ID 10657 Accession 18116
Symbol KHDRBS1 Alias p62;p68;Sam68 Full Name KH RNA binding domain containing, signal transduction associated 1
Status Confidence Length 30010 bases Strand Plus strand
Position 1 : 32013868 - 32043877 RNA binding domain KH_1 , Qua1
Summary This gene encodes a member of the K homology domain-containing, RNA-binding, signal transduction-associated protein family. The encoded protein appears to have many functions and may be involved in a variety of cellular processes, including alternative splicing, cell cycle regulation, RNA 3'-end formation, tumorigenesis, and regulation of human immunodeficiency virus gene expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000313829 Qua1 PF16274 5e-32 1
ENSP00000313829 KH_1 PF00013 3.8e-10 2
ENSP00000417731 Qua1 PF16274 5e-32 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
27415018 Sam68 Mediates the Activation of Insulin and Leptin Signalling in Breast Cancer Cells. Antonio Pérez-Pérez 2016-01-01 PloS one
26870154 Whole-Exome Sequencing Identifies Novel Somatic Mutations in Chinese Breast Cancer Patients. Yanfeng Zhang 2015-12-01 Journal of molecular and genetic medicine : an international journal of biomedical research
31475030 The Length of the Expressed 3' UTR Is an Intermediate Molecular Phenotype Linking Genetic Variants to Complex Diseases. Elisa Mariella 2019-01-01 Frontiers in genetics
33213024 Leptin, Leptin Receptor, KHDRBS1 (KH RNA Binding Domain Containing, Signal Transduction Associated 1), and Adiponectin in Bone Metastasis from Breast Carcinoma: An Immunohistochemical Study. Paola Maroni 2020-11-17 Biomedicines
27235792 Sam68 modulates apoptosis of intestinal epithelial cells via mediating NF-κB activation in ulcerative colitis. Ji Qian 2016-07-01 Molecular immunology
31440515 Post-transcriptional Regulation of Colorectal Cancer: A Focus on RNA-Binding Proteins. M Jennyfer García-Cárdenas 2019-01-01 Frontiers in molecular biosciences
26310125 The RNA-binding protein Sam68 regulates expression and transcription function of the androgen receptor splice variant AR-V7. Jacqueline Stockley 2015-08-27 Scientific reports
32375121 Sam68 mediates leptin signaling and action in human granulosa cells: possible role in leptin resistance in PCOS. Teresa Vilariño-García 2020-06-01 Endocrine connections
23443080 Cancer cell response to anthracyclines effects: mysteries of the hidden proteins associated with these drugs. Jirina Tyleckova 2012-11-22 International journal of molecular sciences
32099950 Genetics of Primary Ovarian Insufficiency in the Next-Generation Sequencing Era. Malheiros Monica França 2020-02-01 Journal of the Endocrine Society
30733805 Aldehyde Dehydrogenases: Not Just Markers, but Functional Regulators of Stem Cells. Giuseppe Vassalli 2019-01-01 Stem cells international
37208334 ADAR1-mediated RNA editing of SCD1 drives drug resistance and self-renewal in gastric cancer. Tin-Lok Wong 2023-05-19 Nature communications
36335100 RNA-binding proteins of KHDRBS and IGF2BP families control the oncogenic activity of MLL-AF4. Hiroshi Okuda 2022-11-05 Nature communications

Transcripts

Name Transcript ID bp Protein Translation ID
KHDRBS1-202 ENST00000327300 2713 443aa ENSP00000313829
KHDRBS1-201 ENST00000307714 2738 No protein -
KHDRBS1-204 ENST00000492989 1215 404aa ENSP00000417731
KHDRBS1-203 ENST00000484270 1989 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
44567Platelet Function Tests2.7909900E-005-

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000121774homo_sapiensENSP0000036660720.500812.3631homo_sapiensENSP0000031382929.571117.833
ENSG00000121774homo_sapiensENSP0000028115673.352463.3238homo_sapiensENSP0000031382957.787849.8871
ENSG00000121774homo_sapiensENSP0000035509443.108533.1378homo_sapiensENSP0000031382933.182825.5079
ENSG00000121774homo_sapiensENSP0000034810870.231258.9595homo_sapiensENSP0000031382954.853346.0497

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000121774homo_sapiensENSP0000031382980.361277.2009nomascus_leucogenysENSNLEP0000000260691.282187.6923
ENSG00000121774homo_sapiensENSP00000313829100100pan_paniscusENSPPAP00000024640100100
ENSG00000121774homo_sapiensENSP00000313829100100pongo_abeliiENSPPYP0000000185080.987280.9872
ENSG00000121774homo_sapiensENSP00000313829100100pan_troglodytesENSPTRP00000000822100100
ENSG00000121774homo_sapiensENSP00000313829100100gorilla_gorillaENSGGOP00000008439100100
ENSG00000121774homo_sapiensENSP0000031382993.22890.7449ornithorhynchus_anatinusENSOANP0000005358776.623474.5826
ENSG00000121774homo_sapiensENSP0000031382993.679591.1964sarcophilus_harrisiiENSSHAP0000000819992.222289.7778
ENSG00000121774homo_sapiensENSP0000031382953.047451.4673notamacropus_eugeniiENSMEUP0000001435676.298774.026
ENSG00000121774homo_sapiensENSP0000031382983.747283.2957choloepus_hoffmanniENSCHOP0000000618083.936783.4842
ENSG00000121774homo_sapiensENSP0000031382955.530555.3047choloepus_hoffmanniENSCHOP0000000573898.795298.3936
ENSG00000121774homo_sapiensENSP0000031382998.419998.1941dasypus_novemcinctusENSDNOP0000003436498.419998.1941
ENSG00000121774homo_sapiensENSP0000031382982.618580.3612erinaceus_europaeusENSEEUP0000000184083.94581.6514
ENSG00000121774homo_sapiensENSP0000031382956.433456.2077echinops_telfairiENSETEP0000001270898.814298.419
ENSG00000121774homo_sapiensENSP00000313829100100callithrix_jacchusENSCJAP00000012221100100
ENSG00000121774homo_sapiensENSP0000031382988.713386.6817callithrix_jacchusENSCJAP0000007822894.927592.7536
ENSG00000121774homo_sapiensENSP00000313829100100cercocebus_atysENSCATP00000043863100100
ENSG00000121774homo_sapiensENSP0000031382996.388395.9368macaca_fascicularisENSMFAP0000000852578.205177.8388
ENSG00000121774homo_sapiensENSP00000313829100100macaca_mulattaENSMMUP00000030856100100
ENSG00000121774homo_sapiensENSP00000313829100100macaca_nemestrinaENSMNEP00000024109100100
ENSG00000121774homo_sapiensENSP00000313829100100papio_anubisENSPANP0000000672080.987280.9872
ENSG00000121774homo_sapiensENSP0000031382981.038481.0384mandrillus_leucophaeusENSMLEP0000001724099.171399.1713
ENSG00000121774homo_sapiensENSP0000031382999.774399.7743tursiops_truncatusENSTTRP0000000911899.774399.7743
ENSG00000121774homo_sapiensENSP0000031382999.774399.7743vulpes_vulpesENSVVUP0000002042299.774399.7743
ENSG00000121774homo_sapiensENSP0000031382996.61494.3567mus_spretusMGP_SPRETEiJ_P006719796.61494.3567
ENSG00000121774homo_sapiensENSP0000031382999.548599.5485equus_asinusENSEASP0000501569099.548599.5485
ENSG00000121774homo_sapiensENSP0000031382999.548599.5485capra_hircusENSCHIP0000001063899.548599.5485
ENSG00000121774homo_sapiensENSP0000031382985.778885.3273loxodonta_africanaENSLAFP0000000789098.445697.9275
ENSG00000121774homo_sapiensENSP0000031382999.774399.7743panthera_leoENSPLOP0000000899899.774399.7743
ENSG00000121774homo_sapiensENSP0000031382999.774399.7743ailuropoda_melanoleucaENSAMEP0000000841399.774399.7743
ENSG00000121774homo_sapiensENSP0000031382999.548599.5485bos_indicus_hybridENSBIXP0000500777062.910162.9101
ENSG00000121774homo_sapiensENSP0000031382999.548599.3228oryctolagus_cuniculusENSOCUP0000000662199.548599.3228
ENSG00000121774homo_sapiensENSP0000031382993.22893.228equus_caballusENSECAP0000001697597.405797.4057
ENSG00000121774homo_sapiensENSP0000031382999.774399.7743canis_lupus_familiarisENSCAFP0084500717499.774399.7743
ENSG00000121774homo_sapiensENSP0000031382999.774399.7743panthera_pardusENSPPRP0000001752099.774399.7743
ENSG00000121774homo_sapiensENSP0000031382973.363472.2348marmota_marmota_marmotaENSMMMP0000001033997.014995.5224
ENSG00000121774homo_sapiensENSP0000031382999.774399.7743balaenoptera_musculusENSBMSP0001000670599.774399.7743
ENSG00000121774homo_sapiensENSP0000031382999.548599.0971cavia_porcellusENSCPOP0000002124393.630693.2059
ENSG00000121774homo_sapiensENSP0000031382999.774399.7743felis_catusENSFCAP0000000604999.774399.7743
ENSG00000121774homo_sapiensENSP0000031382999.774399.7743ursus_americanusENSUAMP0000001120699.774399.7743
ENSG00000121774homo_sapiensENSP0000031382990.970788.0361monodelphis_domesticaENSMODP0000004790178.86576.3209
ENSG00000121774homo_sapiensENSP0000031382959.593753.4989monodelphis_domesticaENSMODP0000003719061.682255.3738
ENSG00000121774homo_sapiensENSP0000031382999.548599.5485bison_bison_bisonENSBBBP0000000354199.548599.5485
ENSG00000121774homo_sapiensENSP0000031382999.774399.5485monodon_monocerosENSMMNP0001501483599.774399.5485
ENSG00000121774homo_sapiensENSP0000031382999.774399.7743sus_scrofaENSSSCP0000002635499.774399.7743
ENSG00000121774homo_sapiensENSP0000031382999.548599.5485microcebus_murinusENSMICP0000003268780.621680.6216
ENSG00000121774homo_sapiensENSP0000031382983.972981.9413octodon_degusENSODEP0000000440891.625689.4089
ENSG00000121774homo_sapiensENSP0000031382997.742797.2912jaculus_jaculusENSJJAP0000001432297.963897.5113
ENSG00000121774homo_sapiensENSP0000031382999.548599.5485ovis_aries_rambouilletENSOARP0002000837999.548599.5485
ENSG00000121774homo_sapiensENSP0000031382978.329678.3296ursus_maritimusENSUMAP00000011400100100
ENSG00000121774homo_sapiensENSP0000031382983.747282.6185ochotona_princepsENSOPRP0000000471490.487889.2683
ENSG00000121774homo_sapiensENSP0000031382999.774399.7743delphinapterus_leucasENSDLEP0000002236799.774399.7743
ENSG00000121774homo_sapiensENSP0000031382999.774399.7743physeter_catodonENSPCTP0000500087899.774399.7743
ENSG00000121774homo_sapiensENSP0000031382996.61494.3567mus_caroliMGP_CAROLIEiJ_P006467896.61494.3567
ENSG00000121774homo_sapiensENSP0000031382996.61494.3567mus_musculusENSMUSP0000006651696.61494.3567
ENSG00000121774homo_sapiensENSP0000031382997.065596.1625dipodomys_ordiiENSDORP0000001083597.505796.5986
ENSG00000121774homo_sapiensENSP0000031382999.774399.7743mustela_putorius_furoENSMPUP0000001524399.774399.7743
ENSG00000121774homo_sapiensENSP00000313829100100aotus_nancymaaeENSANAP00000018177100100
ENSG00000121774homo_sapiensENSP0000031382983.0783.07saimiri_boliviensis_boliviensisENSSBOP00000030556100100
ENSG00000121774homo_sapiensENSP0000031382999.774399.5485vicugna_pacosENSVPAP0000000647699.774399.5485
ENSG00000121774homo_sapiensENSP00000313829100100chlorocebus_sabaeusENSCSAP0000001697080.987280.9872
ENSG00000121774homo_sapiensENSP0000031382968.62368.3973tupaia_belangeriENSTBEP0000001465697.124696.8051
ENSG00000121774homo_sapiensENSP0000031382984.198680.3612mesocricetus_auratusENSMAUP0000001549591.421687.2549
ENSG00000121774homo_sapiensENSP0000031382999.774399.7743phocoena_sinusENSPSNP0000001546999.774399.7743
ENSG00000121774homo_sapiensENSP0000031382999.774399.5485camelus_dromedariusENSCDRP0000502976799.774399.5485
ENSG00000121774homo_sapiensENSP0000031382994.130994.1309carlito_syrichtaENSTSYP0000000449995.205595.2055
ENSG00000121774homo_sapiensENSP0000031382983.747283.7472panthera_tigris_altaicaENSPTIP0000000569883.747283.7472
ENSG00000121774homo_sapiensENSP0000031382996.61494.3567rattus_norvegicusENSRNOP0000006689496.61494.3567
ENSG00000121774homo_sapiensENSP0000031382999.548599.5485prolemur_simusENSPSMP0000002936299.548599.5485
ENSG00000121774homo_sapiensENSP0000031382997.742795.4853microtus_ochrogasterENSMOCP0000002642097.742795.4853
ENSG00000121774homo_sapiensENSP0000031382981.038480.3612sorex_araneusENSSARP0000000766581.221780.543
ENSG00000121774homo_sapiensENSP0000031382997.742795.4853peromyscus_maniculatus_bairdiiENSPEMP0000002877397.742795.4853
ENSG00000121774homo_sapiensENSP0000031382983.0783.07bos_mutusENSBMUP0000001126483.446783.4467
ENSG00000121774homo_sapiensENSP0000031382996.61494.3567mus_spicilegusENSMSIP0000000114796.61494.3567
ENSG00000121774homo_sapiensENSP0000031382997.742795.2596cricetulus_griseus_chok1gshdENSCGRP0000101849597.742795.2596
ENSG00000121774homo_sapiensENSP0000031382999.097199.0971pteropus_vampyrusENSPVAP0000001253499.097199.0971
ENSG00000121774homo_sapiensENSP0000031382998.645698.1941myotis_lucifugusENSMLUP0000000740698.645698.1941
ENSG00000121774homo_sapiensENSP0000031382993.679590.9707vombatus_ursinusENSVURP0001000092592.222289.5556
ENSG00000121774homo_sapiensENSP0000031382998.871398.4199rhinolophus_ferrumequinumENSRFEP0001001919098.871398.4199
ENSG00000121774homo_sapiensENSP0000031382999.774399.7743neovison_visonENSNVIP0000003154299.774399.7743
ENSG00000121774homo_sapiensENSP0000031382999.548599.5485bos_taurusENSBTAP0000001658199.548599.5485
ENSG00000121774homo_sapiensENSP0000031382999.548599.3228heterocephalus_glaber_femaleENSHGLP0000001667799.548599.3228
ENSG00000121774homo_sapiensENSP00000313829100100rhinopithecus_bietiENSRBIP00000008983100100
ENSG00000121774homo_sapiensENSP0000031382999.774399.7743canis_lupus_dingoENSCAFP0002003229499.774399.7743
ENSG00000121774homo_sapiensENSP0000031382999.774399.5485sciurus_vulgarisENSSVLP0000502593399.774399.5485
ENSG00000121774homo_sapiensENSP0000031382993.453790.7449phascolarctos_cinereusENSPCIP0000002997692.204989.5323
ENSG00000121774homo_sapiensENSP0000031382998.871398.6456procavia_capensisENSPCAP0000000917999.09598.8688
ENSG00000121774homo_sapiensENSP0000031382997.968496.8397nannospalax_galiliENSNGAP0000002199497.968496.8397
ENSG00000121774homo_sapiensENSP0000031382999.548599.5485bos_grunniensENSBGRP0000001720163.271263.2712
ENSG00000121774homo_sapiensENSP0000031382999.548599.3228chinchilla_lanigeraENSCLAP0000002296799.548599.3228
ENSG00000121774homo_sapiensENSP0000031382999.548599.5485cervus_hanglu_yarkandensisENSCHYP0000001921099.548599.5485
ENSG00000121774homo_sapiensENSP0000031382999.548599.3228catagonus_wagneriENSCWAP0000001785899.548599.3228
ENSG00000121774homo_sapiensENSP0000031382999.774399.5485ictidomys_tridecemlineatusENSSTOP0000001266999.774399.5485
ENSG00000121774homo_sapiensENSP0000031382999.774399.7743otolemur_garnettiiENSOGAP0000000408999.549699.5496
ENSG00000121774homo_sapiensENSP0000031382990.970790.7449cebus_imitatorENSCCAP0000003298397.815597.5728
ENSG00000121774homo_sapiensENSP0000031382999.774399.5485urocitellus_parryiiENSUPAP0001002376591.891991.684
ENSG00000121774homo_sapiensENSP0000031382999.548599.5485moschus_moschiferusENSMMSP0000000661799.548599.5485
ENSG00000121774homo_sapiensENSP00000313829100100rhinopithecus_roxellanaENSRROP0000004052480.987280.9872
ENSG00000121774homo_sapiensENSP0000031382995.033993.0023mus_pahariMGP_PahariEiJ_P007976895.033993.0023
ENSG00000121774homo_sapiensENSP0000031382999.548599.3228propithecus_coquereliENSPCOP0000001568299.548599.3228
ENSG00000121774homo_sapiensENSP0000031382986.45685.553propithecus_coquereliENSPCOP0000002538890.330289.3868
ENSG00000121774homo_sapiensENSP0000031382933.8621.6704drosophila_melanogasterFBpp030975630.487819.5122
ENSG00000121774homo_sapiensENSP0000031382935.214425.2822drosophila_melanogasterFBpp007175439.393928.2828
ENSG00000121774homo_sapiensENSP0000031382934.988723.702drosophila_melanogasterFBpp007163348.589332.9154
ENSG00000121774homo_sapiensENSP0000031382942.437927.7652drosophila_melanogasterFBpp030388130.4719.9352
ENSG00000121774homo_sapiensENSP0000031382931.37722.1219drosophila_melanogasterFBpp007176451.481536.2963
ENSG00000121774homo_sapiensENSP0000031382936.117424.3792drosophila_melanogasterFBpp031160747.058831.7647
ENSG00000121774homo_sapiensENSP0000031382936.117424.605drosophila_melanogasterFBpp030862150.473234.3849
ENSG00000121774homo_sapiensENSP0000031382934.76321.4447drosophila_melanogasterFBpp030861837.019222.8365
ENSG00000121774homo_sapiensENSP0000031382952.821741.535petromyzon_marinusENSPMAP0000000502363.243249.7297
ENSG00000121774homo_sapiensENSP0000031382934.537227.991eptatretus_burgeriENSEBUP0000000316348.26539.1167
ENSG00000121774homo_sapiensENSP0000031382962.75457.7878latimeria_chalumnaeENSLACP0000001175287.421480.5031
ENSG00000121774homo_sapiensENSP0000031382965.914259.3679lepisosteus_oculatusENSLOCP0000000266381.564273.4637
ENSG00000121774homo_sapiensENSP0000031382960.948154.4018clupea_harengusENSCHAP0000004215775.630267.507
ENSG00000121774homo_sapiensENSP0000031382960.722353.0474clupea_harengusENSCHAP0000003808367.758259.194
ENSG00000121774homo_sapiensENSP0000031382961.399553.4989danio_rerioENSDARP0000009424777.272767.3295
ENSG00000121774homo_sapiensENSP0000031382959.593750.5643danio_rerioENSDARP0000006927371.351360.5405
ENSG00000121774homo_sapiensENSP0000031382958.239347.6298carassius_auratusENSCARP0000011781566.666754.522
ENSG00000121774homo_sapiensENSP0000031382960.722351.0158carassius_auratusENSCARP0000008140272.11860.5898
ENSG00000121774homo_sapiensENSP0000031382960.045150.1129carassius_auratusENSCARP0000007776670.184758.5752
ENSG00000121774homo_sapiensENSP0000031382960.045150.1129carassius_auratusENSCARP0000002827370.184758.5752
ENSG00000121774homo_sapiensENSP0000031382961.173853.9503carassius_auratusENSCARP0000010582176.988667.8977
ENSG00000121774homo_sapiensENSP0000031382961.625352.1445carassius_auratusENSCARP0000011675877.556865.625
ENSG00000121774homo_sapiensENSP0000031382962.302552.3702astyanax_mexicanusENSAMXP0000000289971.13459.7938
ENSG00000121774homo_sapiensENSP0000031382961.173853.4989astyanax_mexicanusENSAMXP0000002723368.956760.3053
ENSG00000121774homo_sapiensENSP0000031382961.85155.3047ictalurus_punctatusENSIPUP0000002100278.285770
ENSG00000121774homo_sapiensENSP0000031382958.46549.4357ictalurus_punctatusENSIPUP0000002923862.560452.8986
ENSG00000121774homo_sapiensENSP0000031382961.85155.3047esox_luciusENSELUP0000003866673.854466.0377
ENSG00000121774homo_sapiensENSP0000031382963.205454.1761esox_luciusENSELUP0000000255569.135859.2593
ENSG00000121774homo_sapiensENSP0000031382963.656954.8533electrophorus_electricusENSEEEP0000001823679.436668.4507
ENSG00000121774homo_sapiensENSP0000031382953.950345.5982electrophorus_electricusENSEEEP0000001677672.424261.2121
ENSG00000121774homo_sapiensENSP0000031382961.85154.8533oncorhynchus_kisutchENSOKIP0000508376374.054165.6757
ENSG00000121774homo_sapiensENSP0000031382960.948154.4018oncorhynchus_kisutchENSOKIP0000506070975.41967.3184
ENSG00000121774homo_sapiensENSP0000031382962.076754.4018oncorhynchus_kisutchENSOKIP0000503311469.79761.1675
ENSG00000121774homo_sapiensENSP0000031382964.334155.7562oncorhynchus_kisutchENSOKIP0000504803871.2561.75
ENSG00000121774homo_sapiensENSP0000031382960.496653.9503oncorhynchus_mykissENSOMYP0000013753074.860366.7598
ENSG00000121774homo_sapiensENSP0000031382961.85154.1761oncorhynchus_mykissENSOMYP0000009616470.076761.3811
ENSG00000121774homo_sapiensENSP0000031382964.334155.7562oncorhynchus_mykissENSOMYP0000006535571.2561.75
ENSG00000121774homo_sapiensENSP0000031382962.076754.8533oncorhynchus_mykissENSOMYP0000000725274.324365.6757
ENSG00000121774homo_sapiensENSP0000031382964.108455.3047salmo_salarENSSSAP0000001020571.356861.5578
ENSG00000121774homo_sapiensENSP0000031382961.399554.6275salmo_salarENSSSAP0000007504877.272768.75
ENSG00000121774homo_sapiensENSP0000031382961.173854.6275salmo_salarENSSSAP0000004950474.655666.6667
ENSG00000121774homo_sapiensENSP0000031382962.302554.6275salmo_salarENSSSAP0000000474970.050861.4213
ENSG00000121774homo_sapiensENSP0000031382964.334155.7562salmo_truttaENSSTUP0000004658671.072361.596
ENSG00000121774homo_sapiensENSP0000031382961.399554.8533salmo_truttaENSSTUP0000009235674.316966.3934
ENSG00000121774homo_sapiensENSP0000031382957.110650.5643salmo_truttaENSSTUP0000004800068.7560.8696
ENSG00000121774homo_sapiensENSP0000031382962.302554.6275salmo_truttaENSSTUP0000010858870.050861.4213
ENSG00000121774homo_sapiensENSP0000031382961.399554.1761gadus_morhuaENSGMOP0000002419275.138166.2983
ENSG00000121774homo_sapiensENSP0000031382959.367950.5643gadus_morhuaENSGMOP0000001250465.7556
ENSG00000121774homo_sapiensENSP0000031382961.85154.4018fundulus_heteroclitusENSFHEP0000001547875.900366.759
ENSG00000121774homo_sapiensENSP0000031382958.013549.2099fundulus_heteroclitusENSFHEP0000001586369.272258.7601
ENSG00000121774homo_sapiensENSP0000031382961.399554.1761poecilia_reticulataENSPREP0000002486475.138166.2983
ENSG00000121774homo_sapiensENSP0000031382958.46549.4357poecilia_reticulataENSPREP0000003242869.811359.0296
ENSG00000121774homo_sapiensENSP0000031382961.173853.9503xiphophorus_maculatusENSXMAP0000004141872.849564.2473
ENSG00000121774homo_sapiensENSP0000031382958.013548.9842xiphophorus_maculatusENSXMAP0000000644269.272258.4906
ENSG00000121774homo_sapiensENSP0000031382957.787847.8555oryzias_latipesENSORLP0000002146668.817256.9892
ENSG00000121774homo_sapiensENSP0000031382958.239348.5327oryzias_latipesENSORLP0000002927768.98457.4866
ENSG00000121774homo_sapiensENSP0000031382958.013548.0813cyclopterus_lumpusENSCLMP0000502433469.08657.2581
ENSG00000121774homo_sapiensENSP0000031382960.722353.0474cyclopterus_lumpusENSCLMP0000501452676.420566.7614
ENSG00000121774homo_sapiensENSP0000031382960.496650.7901oreochromis_niloticusENSONIP000000153886756.25
ENSG00000121774homo_sapiensENSP0000031382950.338644.0181oreochromis_niloticusENSONIP0000004982859.946252.4194
ENSG00000121774homo_sapiensENSP0000031382962.528255.3047haplochromis_burtoniENSHBUP0000002079576.519367.6796
ENSG00000121774homo_sapiensENSP0000031382960.948151.2415haplochromis_burtoniENSHBUP0000001359567.556.75
ENSG00000121774homo_sapiensENSP0000031382962.528255.3047astatotilapia_callipteraENSACLP0000001897276.519367.6796
ENSG00000121774homo_sapiensENSP0000031382960.722351.0158astatotilapia_callipteraENSACLP0000000586567.2556.5
ENSG00000121774homo_sapiensENSP0000031382961.85154.4018sparus_aurataENSSAUP0001000166176.323167.1309
ENSG00000121774homo_sapiensENSP0000031382958.46548.307sparus_aurataENSSAUP0001004933467.62455.8747
ENSG00000121774homo_sapiensENSP0000031382960.270950.5643lates_calcariferENSLCAP0001002077066.7556
ENSG00000121774homo_sapiensENSP0000031382956.884950.1129lates_calcariferENSLCAP0001000204476.363667.2727
ENSG00000121774homo_sapiensENSP0000031382968.397362.754xenopus_tropicalisENSXETP0000006743484.166777.2222
ENSG00000121774homo_sapiensENSP0000031382988.036184.6501chrysemys_picta_belliiENSCPBP0000001494892.857189.2857
ENSG00000121774homo_sapiensENSP0000031382988.036185.1016sphenodon_punctatusENSSPUP0000002331185.526382.6754
ENSG00000121774homo_sapiensENSP0000031382970.428968.3973crocodylus_porosusENSCPRP0000500214293.413290.7186
ENSG00000121774homo_sapiensENSP0000031382981.489877.4266laticauda_laticaudataENSLLTP0000001678486.157581.8616
ENSG00000121774homo_sapiensENSP0000031382972.460569.3002notechis_scutatusENSNSUP0000001611780.451176.9424
ENSG00000121774homo_sapiensENSP0000031382982.392878.781pseudonaja_textilisENSPTXP0000000570485.280481.5421
ENSG00000121774homo_sapiensENSP0000031382988.487685.7788anas_platyrhynchos_platyrhynchosENSAPLP0000002129268.531566.4336
ENSG00000121774homo_sapiensENSP0000031382986.230283.2957gallus_gallusENSGALP0001002442977.959275.3061
ENSG00000121774homo_sapiensENSP0000031382972.234869.0745meleagris_gallopavoENSMGAP0000003443890.140886.1972
ENSG00000121774homo_sapiensENSP0000031382921.21918.9616serinus_canariaENSSCAP0000000630279.66171.1864
ENSG00000121774homo_sapiensENSP0000031382982.618579.0068parus_majorENSPMJP0000000740588.619984.7458
ENSG00000121774homo_sapiensENSP0000031382962.528260.0451anolis_carolinensisENSACAP0000001153490.819787.2131
ENSG00000121774homo_sapiensENSP0000031382962.302555.079neolamprologus_brichardiENSNBRP0000000049276.243167.4033
ENSG00000121774homo_sapiensENSP0000031382960.722351.0158neolamprologus_brichardiENSNBRP0000000039767.2556.5
ENSG00000121774homo_sapiensENSP0000031382985.778881.7156naja_najaENSNNAP0000002713687.557683.4101
ENSG00000121774homo_sapiensENSP0000031382986.004581.9413podarcis_muralisENSPMRP0000001437085.61881.573
ENSG00000121774homo_sapiensENSP0000031382961.173857.1106geospiza_fortisENSGFOP0000002154477.873672.7011
ENSG00000121774homo_sapiensENSP0000031382975.620873.1377taeniopygia_guttataENSTGUP0000001762393.314890.2507
ENSG00000121774homo_sapiensENSP0000031382961.399553.7246erpetoichthys_calabaricusENSECRP0000001792582.674872.3404
ENSG00000121774homo_sapiensENSP0000031382961.85155.3047kryptolebias_marmoratusENSKMAP0000000209775.690667.6796
ENSG00000121774homo_sapiensENSP0000031382959.142249.2099kryptolebias_marmoratusENSKMAP0000002001370.241358.445
ENSG00000121774homo_sapiensENSP0000031382986.681782.6185salvator_merianaeENSSMRP0000001540888.275984.1379
ENSG00000121774homo_sapiensENSP0000031382961.399553.7246oryzias_javanicusENSOJAP0000001114675.76666.2953
ENSG00000121774homo_sapiensENSP0000031382958.916548.5327oryzias_javanicusENSOJAP0000003779469.973257.6408
ENSG00000121774homo_sapiensENSP0000031382962.076755.079amphilophus_citrinellusENSACIP0000000828576.815668.1564
ENSG00000121774homo_sapiensENSP0000031382958.46550.1129amphilophus_citrinellusENSACIP0000001975566.925157.3643
ENSG00000121774homo_sapiensENSP0000031382962.076754.6275dicentrarchus_labraxENSDLAP0000504183676.177367.036
ENSG00000121774homo_sapiensENSP0000031382960.496650.7901amphiprion_perculaENSAPEP000000300776756.25
ENSG00000121774homo_sapiensENSP0000031382962.076754.1761amphiprion_perculaENSAPEP0000000481977.247267.4157
ENSG00000121774homo_sapiensENSP0000031382961.85153.2731oryzias_sinensisENSOSIP0000001616576.111165.5556
ENSG00000121774homo_sapiensENSP0000031382957.787848.0813oryzias_sinensisENSOSIP0000002802368.085156.6489
ENSG00000121774homo_sapiensENSP0000031382969.977468.1716pelodiscus_sinensisENSPSIP0000000620595.67993.2099
ENSG00000121774homo_sapiensENSP0000031382987.810484.4244gopherus_evgoodeiENSGEVP0000501304792.61989.0476
ENSG00000121774homo_sapiensENSP0000031382972.00969.9774chelonoidis_abingdoniiENSCABP0000002568187.158584.6995
ENSG00000121774homo_sapiensENSP0000031382960.722350.5643seriola_dumeriliENSSDUP0000001477267.2556
ENSG00000121774homo_sapiensENSP0000031382962.75455.7562seriola_dumeriliENSSDUP0000000190776.795668.232
ENSG00000121774homo_sapiensENSP0000031382961.173854.1761cottoperca_gobioENSCGOP0000002068574.861966.2983
ENSG00000121774homo_sapiensENSP0000031382959.819449.4357cottoperca_gobioENSCGOP0000000522768.123456.2982
ENSG00000121774homo_sapiensENSP0000031382974.492170.2032struthio_camelus_australisENSSCUP0000000125488.471883.378
ENSG00000121774homo_sapiensENSP0000031382988.487686.0045anser_brachyrhynchusENSABRP0000002431288.888986.3946
ENSG00000121774homo_sapiensENSP0000031382948.532741.7607gasterosteus_aculeatusENSGACP0000001216767.823358.3596
ENSG00000121774homo_sapiensENSP0000031382958.013548.307gasterosteus_aculeatusENSGACP0000000870266.580355.4404
ENSG00000121774homo_sapiensENSP0000031382961.399554.6275cynoglossus_semilaevisENSCSEP0000001860675.977767.5978
ENSG00000121774homo_sapiensENSP0000031382958.013548.307cynoglossus_semilaevisENSCSEP0000000022265.394454.4529
ENSG00000121774homo_sapiensENSP0000031382960.948153.7246poecilia_formosaENSPFOP0000001223672.580663.9785
ENSG00000121774homo_sapiensENSP0000031382958.916549.8871poecilia_formosaENSPFOP0000002842169.047658.4656
ENSG00000121774homo_sapiensENSP0000031382960.045151.9187myripristis_murdjanENSMMDP0000504436966.834257.7889
ENSG00000121774homo_sapiensENSP0000031382961.85155.5305myripristis_murdjanENSMMDP0000500789976.111168.3333
ENSG00000121774homo_sapiensENSP0000031382960.270950.3386sander_luciopercaENSSLUP0000000361768.112256.8878
ENSG00000121774homo_sapiensENSP0000031382962.076754.6275sander_luciopercaENSSLUP0000002888475.966966.8508
ENSG00000121774homo_sapiensENSP0000031382986.004582.6185strigops_habroptilaENSSHBP0000501931587.385383.945
ENSG00000121774homo_sapiensENSP0000031382958.46549.4357amphiprion_ocellarisENSAOCP0000002877567.447957.0312
ENSG00000121774homo_sapiensENSP0000031382962.302554.4018amphiprion_ocellarisENSAOCP0000000253477.528167.6966
ENSG00000121774homo_sapiensENSP0000031382988.036184.6501terrapene_carolina_triunguisENSTMTP0000000502592.857189.2857
ENSG00000121774homo_sapiensENSP0000031382962.076755.5305hucho_huchoENSHHUP0000000240875.757667.7686
ENSG00000121774homo_sapiensENSP0000031382962.076754.4018hucho_huchoENSHHUP0000006561269.444460.8586
ENSG00000121774homo_sapiensENSP0000031382964.108455.7562hucho_huchoENSHHUP000000683707161.75
ENSG00000121774homo_sapiensENSP0000031382916.027112.8668hucho_huchoENSHHUP0000002450575.531960.6383
ENSG00000121774homo_sapiensENSP0000031382959.593749.2099betta_splendensENSBSLP0000005253870.458.1333
ENSG00000121774homo_sapiensENSP0000031382962.75453.9503betta_splendensENSBSLP0000001082777.222266.3889
ENSG00000121774homo_sapiensENSP0000031382966.365755.3047pygocentrus_nattereriENSPNAP0000002952063.498952.9158
ENSG00000121774homo_sapiensENSP0000031382961.85153.9503pygocentrus_nattereriENSPNAP0000003777777.401167.5141
ENSG00000121774homo_sapiensENSP0000031382962.302553.9503anabas_testudineusENSATEP0000001073076.454366.205
ENSG00000121774homo_sapiensENSP0000031382959.819450.1129anabas_testudineusENSATEP0000000784266.582955.7789
ENSG00000121774homo_sapiensENSP0000031382960.722350.5643seriola_lalandi_dorsalisENSSLDP0000000375367.2556
ENSG00000121774homo_sapiensENSP0000031382961.85154.8533seriola_lalandi_dorsalisENSSLDP0000000654676.536367.8771
ENSG00000121774homo_sapiensENSP0000031382954.401847.6298labrus_bergyltaENSLBEP0000001285271.940362.9851
ENSG00000121774homo_sapiensENSP0000031382960.045149.4357labrus_bergyltaENSLBEP0000003338466.554.75
ENSG00000121774homo_sapiensENSP0000031382960.722351.0158pundamilia_nyerereiENSPNYP0000000192367.2556.5
ENSG00000121774homo_sapiensENSP0000031382962.528255.3047pundamilia_nyerereiENSPNYP0000000595176.519367.6796
ENSG00000121774homo_sapiensENSP0000031382961.625354.1761mastacembelus_armatusENSMAMP0000000632576.470667.2269
ENSG00000121774homo_sapiensENSP0000031382960.496649.4357mastacembelus_armatusENSMAMP000000125106754.75
ENSG00000121774homo_sapiensENSP0000031382962.076754.4018stegastes_partitusENSSPAP0000000082576.815667.3184
ENSG00000121774homo_sapiensENSP0000031382960.722350.5643stegastes_partitusENSSPAP0000002768967.2556
ENSG00000121774homo_sapiensENSP0000031382947.855541.535oncorhynchus_tshawytschaENSOTSP0000504513665.634756.9659
ENSG00000121774homo_sapiensENSP0000031382923.024819.6388oncorhynchus_tshawytschaENSOTSP0000507830080.952469.0476
ENSG00000121774homo_sapiensENSP0000031382962.076754.4018oncorhynchus_tshawytschaENSOTSP0000500946969.974661.3232
ENSG00000121774homo_sapiensENSP0000031382964.559855.7562oncorhynchus_tshawytschaENSOTSP0000501561971.561.75
ENSG00000121774homo_sapiensENSP0000031382941.083534.3115oncorhynchus_tshawytschaENSOTSP0000505931842.129635.1852
ENSG00000121774homo_sapiensENSP0000031382960.722350.7901acanthochromis_polyacanthusENSAPOP0000002690867.2556.25
ENSG00000121774homo_sapiensENSP0000031382962.076754.1761acanthochromis_polyacanthusENSAPOP0000002127077.247267.4157
ENSG00000121774homo_sapiensENSP0000031382984.650180.3612aquila_chrysaetos_chrysaetosENSACCP0002001193177.962674.0125
ENSG00000121774homo_sapiensENSP0000031382959.367949.8871nothobranchius_furzeriENSNFUP0001504869270.889559.5687
ENSG00000121774homo_sapiensENSP0000031382962.076754.4018nothobranchius_furzeriENSNFUP0001502868575.757666.3912
ENSG00000121774homo_sapiensENSP0000031382957.787848.9842cyprinodon_variegatusENSCVAP0000001066069.002758.4906
ENSG00000121774homo_sapiensENSP0000031382948.984242.4379cyprinodon_variegatusENSCVAP0000002876252.542445.5206
ENSG00000121774homo_sapiensENSP0000031382967.042957.3363denticeps_clupeoidesENSDCDP0000000136464.847255.4585
ENSG00000121774homo_sapiensENSP0000031382964.785657.7878denticeps_clupeoidesENSDCDP0000004827168.990461.5385
ENSG00000121774homo_sapiensENSP0000031382964.785657.7878denticeps_clupeoidesENSDCDP0000002593370.171262.5917
ENSG00000121774homo_sapiensENSP0000031382959.819449.6614larimichthys_croceaENSLCRP0000505426970.478758.5106
ENSG00000121774homo_sapiensENSP0000031382962.75455.3047larimichthys_croceaENSLCRP0000504249976.795667.6796
ENSG00000121774homo_sapiensENSP0000031382957.110647.1783takifugu_rubripesENSTRUP0000005804670.670458.3799
ENSG00000121774homo_sapiensENSP0000031382961.173853.9503takifugu_rubripesENSTRUP0000002516475.277866.3889
ENSG00000121774homo_sapiensENSP0000031382958.239348.5327hippocampus_comesENSHCOP0000002482869.729758.1081
ENSG00000121774homo_sapiensENSP0000031382960.270951.693hippocampus_comesENSHCOP0000001464076.504365.616
ENSG00000121774homo_sapiensENSP0000031382960.270950.7901cyprinus_carpio_carpioENSCCRP0000016448571.774260.4839
ENSG00000121774homo_sapiensENSP0000031382960.045150.5643cyprinus_carpio_carpioENSCCRP0000014772765.67955.3086
ENSG00000121774homo_sapiensENSP0000031382962.302553.4989cyprinus_carpio_carpioENSCCRP0000015866272.440962.2047
ENSG00000121774homo_sapiensENSP0000031382961.173854.4018cyprinus_carpio_carpioENSCCRP0000010435976.988668.4659
ENSG00000121774homo_sapiensENSP0000031382974.040669.7517coturnix_japonicaENSCJPP0000500048965.079461.3095
ENSG00000121774homo_sapiensENSP0000031382960.948153.7246poecilia_latipinnaENSPLAP0000002675072.580663.9785
ENSG00000121774homo_sapiensENSP0000031382958.46549.4357poecilia_latipinnaENSPLAP0000002490969.811359.0296
ENSG00000121774homo_sapiensENSP0000031382961.399553.9503sinocyclocheilus_grahamiENSSGRP0000003533077.053867.7054
ENSG00000121774homo_sapiensENSP0000031382959.367949.8871sinocyclocheilus_grahamiENSSGRP0000009104771.273759.8916
ENSG00000121774homo_sapiensENSP0000031382959.367950.3386sinocyclocheilus_grahamiENSSGRP0000002762869.946859.3085
ENSG00000121774homo_sapiensENSP0000031382960.948152.3702sinocyclocheilus_grahamiENSSGRP0000008177076.487365.7224
ENSG00000121774homo_sapiensENSP0000031382960.722351.0158maylandia_zebraENSMZEP0000503625967.2556.5
ENSG00000121774homo_sapiensENSP0000031382962.528255.3047maylandia_zebraENSMZEP0000500092376.519367.6796
ENSG00000121774homo_sapiensENSP0000031382961.625354.1761tetraodon_nigroviridisENSTNIP0000001605275.206666.1157
ENSG00000121774homo_sapiensENSP0000031382959.367948.9842tetraodon_nigroviridisENSTNIP0000002061571.857959.2896
ENSG00000121774homo_sapiensENSP0000031382957.336347.8555paramormyrops_kingsleyaeENSPKIP0000003088774.26961.9883
ENSG00000121774homo_sapiensENSP0000031382964.559858.2393paramormyrops_kingsleyaeENSPKIP0000000967481.2573.2955
ENSG00000121774homo_sapiensENSP0000031382964.559856.8849scleropages_formosusENSSFOP0001503703578.787969.4215
ENSG00000121774homo_sapiensENSP0000031382962.979756.6591scleropages_formosusENSSFOP0001501086879.036871.1048
ENSG00000121774homo_sapiensENSP0000031382966.365758.2393leptobrachium_leishanenseENSLLEP0000000419083.286173.0878
ENSG00000121774homo_sapiensENSP0000031382962.076755.3047scophthalmus_maximusENSSMAP0000003366175.966967.6796
ENSG00000121774homo_sapiensENSP0000031382960.270950.1129scophthalmus_maximusENSSMAP0000001176566.417955.2239
ENSG00000121774homo_sapiensENSP0000031382965.462855.7562oryzias_melastigmaENSOMEP0000000380162.365653.1183
ENSG00000121774homo_sapiensENSP0000031382958.690748.5327oryzias_melastigmaENSOMEP0000003202169.705157.6408

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000082involved_in G1/S transition of mitotic cell cycle1TASHomo_sapiens(9606)Process
GO:0000086involved_in G2/M transition of mitotic cell cycle1ISSHomo_sapiens(9606)Process
GO:0000122involved_in negative regulation of transcription by RNA polymerase II1IEAHomo_sapiens(9606)Process
GO:0000381involved_in regulation of alternative mRNA splicing, via spliceosome2IBA,IDAHomo_sapiens(9606)Process
GO:0003677enables DNA binding1TASHomo_sapiens(9606)Function
GO:0003723enables RNA binding2HDA,IDAHomo_sapiens(9606)Function
GO:0003729enables mRNA binding1IBAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus2IBA,IDAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm1IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol1TASHomo_sapiens(9606)Component
GO:0006397involved_in mRNA processing1IEAHomo_sapiens(9606)Process
GO:0007283involved_in spermatogenesis1IEAHomo_sapiens(9606)Process
GO:0008143enables poly(A) binding2IBA,IDAHomo_sapiens(9606)Function
GO:0008266enables poly(U) RNA binding1IDAHomo_sapiens(9606)Function
GO:0016020located_in membrane2HDA,IDAHomo_sapiens(9606)Component
GO:0017124enables SH3 domain binding1IDAHomo_sapiens(9606)Function
GO:0019904enables protein domain specific binding1IPIHomo_sapiens(9606)Function
GO:0031647NOT involved_in regulation of protein stability1IDAHomo_sapiens(9606)Process
GO:0032991part_of protein-containing complex1IDAHomo_sapiens(9606)Component
GO:0035591enables signaling adaptor activity1IDAHomo_sapiens(9606)Function
GO:0042169enables SH2 domain binding1IDAHomo_sapiens(9606)Function
GO:0042802enables identical protein binding2IDA,IPIHomo_sapiens(9606)Function
GO:0044877enables protein-containing complex binding1IEAHomo_sapiens(9606)Function
GO:0045892involved_in negative regulation of DNA-templated transcription1ISSHomo_sapiens(9606)Process
GO:0045948involved_in positive regulation of translational initiation1IDAHomo_sapiens(9606)Process
GO:0046831involved_in regulation of RNA export from nucleus1ISSHomo_sapiens(9606)Process
GO:0046833involved_in positive regulation of RNA export from nucleus1IDAHomo_sapiens(9606)Process
GO:0050852involved_in T cell receptor signaling pathway1IDAHomo_sapiens(9606)Process
GO:0070618part_of Grb2-Sos complex1IEAHomo_sapiens(9606)Component
GO:1990782enables protein tyrosine kinase binding1IPIHomo_sapiens(9606)Function

Expression