Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases SARS-COV-2
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions Metabolic enzymeE3 ligase
Localizations N.A.
BulkPerturb-seq

Description

Ensembl ID ENSG00000120253 Gene ID 348995 Accession 21182
Symbol NUP43 Alias p42;bA350J20.1 Full Name nucleoporin 43
Status Confidence Length 22246 bases Strand Minus strand
Position 6 : 149724315 - 149746560 RNA binding domain N.A.
Summary Bidirectional transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPCs are composed of subcomplexes, and NUP43 is part of one such subcomplex, Nup107-160 (Loiodice et al., 2004 [PubMed 15146057]).[supplied by OMIM, Mar 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000776colocalizes_with kinetochore1IDAHomo_sapiens(9606)Component
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005635located_in nuclear envelope2IDA,TASHomo_sapiens(9606)Component
GO:0005643part_of nuclear pore1NASHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm1IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol2IDA,TASHomo_sapiens(9606)Component
GO:0006913involved_in nucleocytoplasmic transport1NASHomo_sapiens(9606)Process
GO:0007059involved_in chromosome segregation1IEAHomo_sapiens(9606)Process
GO:0015031involved_in protein transport1IEAHomo_sapiens(9606)Process
GO:0016607located_in nuclear speck1IDAHomo_sapiens(9606)Component
GO:0031080part_of nuclear pore outer ring3IBA,IDA,NASHomo_sapiens(9606)Component
GO:0051028involved_in mRNA transport1IEAHomo_sapiens(9606)Process
GO:0051301involved_in cell division1IEAHomo_sapiens(9606)Process

Expression