RBPWorld - a comprehensive database of RNA Binding Proteins

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RBP World!

Functions and Diseases

RBP Type	Non-canonical_RBPs
Diseases	Disease
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Kinase
Localizations	N.A.
BulkPerturb-seq

Description

Ensembl ID	ENSG00000119638	Gene ID	91754	Accession	18591
Symbol	NEK9	Alias	NC;APUG;NERCC;LCCS10;NERCC1	Full Name	NIMA related kinase 9
Status	Confidence	Length	47992 bases	Strand	Minus strand
Position	14 : 75079353 - 75127344	RNA binding domain	N.A.
Summary	This gene encodes a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. The encoded protein is activated in mitosis and, in turn, activates other family members during mitosis. This protein also mediates cellular processes that are essential for interphase progression. [provided by RefSeq, Jul 2016]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal
25217585	A gemcitabine sensitivity screen identifies a role for NEK9 in the replication stress response.	C Scott Smith	2014-10-01	Nucleic acids research

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
NEK9-201	ENST00000238616	8278	979aa	ENSP00000238616
NEK9-216	ENST00000678037	6172	991aa	ENSP00000504620
NEK9-217	ENST00000678531	6010	861aa	ENSP00000503827
NEK9-218	ENST00000678749	5389	861aa	ENSP00000504104
NEK9-205	ENST00000555405	3357	No protein	-
NEK9-210	ENST00000557026	5177	No protein	-
NEK9-215	ENST00000677700	5551	117aa	ENSP00000503940
NEK9-213	ENST00000676711	4211	No protein	-
NEK9-207	ENST00000555763	837	No protein	-
NEK9-209	ENST00000556170	3975	No protein	-
NEK9-206	ENST00000555537	675	No protein	-
NEK9-212	ENST00000676476	860	No protein	-
NEK9-202	ENST00000553823	2146	592aa	ENSP00000452537
NEK9-211	ENST00000557673	1956	260aa	ENSP00000450943
NEK9-214	ENST00000677411	2667	No protein	-
NEK9-204	ENST00000554258	578	104aa	ENSP00000451604
NEK9-208	ENST00000555961	288	No protein	-
NEK9-203	ENST00000553945	786	38aa	ENSP00000452544

Gene Model

Click here to download ENSG00000119638's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000119638's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000278	involved_in mitotic cell cycle	1	IDA	Homo_sapiens(9606)	Process
GO:0004674	enables protein serine/threonine kinase activity	1	IDA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005524	enables ATP binding	1	IEA	Homo_sapiens(9606)	Function
GO:0005634	located_in nucleus	1	IEA	Homo_sapiens(9606)	Component
GO:0005813	colocalizes_with centrosome	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0005829	located_in cytosol	1	TAS	Homo_sapiens(9606)	Component
GO:0006468	involved_in protein phosphorylation	1	IEA	Homo_sapiens(9606)	Process
GO:0007346	involved_in regulation of mitotic cell cycle	1	IDA	Homo_sapiens(9606)	Process
GO:0019901	enables protein kinase binding	2	IBA,IPI	Homo_sapiens(9606)	Function
GO:0030295	enables protein kinase activator activity	1	IDA	Homo_sapiens(9606)	Function
GO:0046872	enables metal ion binding	1	IEA	Homo_sapiens(9606)	Function
GO:0051301	involved_in cell division	1	IEA	Homo_sapiens(9606)	Process
GO:0106310	enables protein serine kinase activity	1	IEA	Homo_sapiens(9606)	Function

Expression