RBPWorld - a comprehensive database of RNA Binding Proteins

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Functions and Diseases

RBP Type	Non-canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Metabolic enzyme
Localizations	N.A.
BulkPerturb-seq

Description

Ensembl ID	ENSG00000119125	Gene ID	9615	Accession	4212
Symbol	GDA	Alias	GAH;CYPIN;GUANASE;NEDASIN	Full Name	guanine deaminase
Status	Confidence	Length	142599 bases	Strand	Plus strand
Position	9 : 72114595 - 72257193	RNA binding domain	N.A.
Summary	This gene encodes an enzyme responsible for the hydrolytic deamination of guanine. Studies in rat ortholog suggest this gene plays a role in microtubule assembly. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
GDA-203	ENST00000376986	1771	393aa	ENSP00000366185
GDA-202	ENST00000358399	5367	454aa	ENSP00000351170
GDA-206	ENST00000475764	2019	454aa	ENSP00000436619
GDA-207	ENST00000477618	2359	No protein	-
GDA-204	ENST00000414671	694	195aa	ENSP00000403897
GDA-208	ENST00000489618	888	176aa	ENSP00000434682
GDA-205	ENST00000436438	990	179aa	ENSP00000400857
GDA-201	ENST00000238018	2074	471aa	ENSP00000238018
GDA-209	ENST00000545168	5362	380aa	ENSP00000437972

Gene Model

Click here to download ENSG00000119125's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID
8425	Alcohol Drinking	5.60146183386526E-5	-
50967	Autistic Disorder	1.9627000E-005	-
53158	Hydrocortisone	3.4310000E-005	-
53159	Hydrocortisone	4.1080000E-005	-
92973	Suicidal Ideation	8E-7	20877300
92992	Suicidal Ideation	7E-6	20877300

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000119125's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000255	involved_in allantoin metabolic process	1	IEA	Homo_sapiens(9606)	Process
GO:0005829	is_active_in cytosol	2	IBA,TAS	Homo_sapiens(9606)	Component
GO:0006139	involved_in nucleobase-containing compound metabolic process	1	TAS	Homo_sapiens(9606)	Process
GO:0006147	involved_in guanine catabolic process	1	IEA	Homo_sapiens(9606)	Process
GO:0006161	involved_in deoxyguanosine catabolic process	1	IEA	Homo_sapiens(9606)	Process
GO:0007399	involved_in nervous system development	1	TAS	Homo_sapiens(9606)	Process
GO:0008270	enables zinc ion binding	1	IBA	Homo_sapiens(9606)	Function
GO:0008892	enables guanine deaminase activity	1	IBA	Homo_sapiens(9606)	Function
GO:0043605	involved_in amide catabolic process	1	IEA	Homo_sapiens(9606)	Process
GO:0046038	involved_in GMP catabolic process	1	IEA	Homo_sapiens(9606)	Process
GO:0046055	involved_in dGMP catabolic process	1	IEA	Homo_sapiens(9606)	Process
GO:0046098	involved_in guanine metabolic process	1	IBA	Homo_sapiens(9606)	Process

Expression