Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000117419 Gene ID 79033 Accession 17276
Symbol ERI3 Alias PINT1;PRNPIP Full Name ERI1 exoribonuclease family member 3
Status Confidence Length 134191 bases Strand Minus strand
Position 1 : 44221070 - 44355260 RNA binding domain RNase_T
Summary Enables RNA binding activity. Predicted to be involved in exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000361331 RNase_T PF00929 4.4e-42 1
ENSP00000497624 RNase_T PF00929 1.8e-37 1
ENSP00000361333 RNase_T PF00929 2e-37 1
ENSP00000390710 RNase_T PF00929 6.7e-33 1
ENSP00000396764 RNase_T PF00929 1.6e-28 1
ENSP00000412291 RNase_T PF00929 1.2e-27 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
30483483 Cellular Targets for the Treatment of Flavivirus Infections. Khalid Mohammad Zakaria 2018-01-01 Frontiers in cellular and infection microbiology
32682290 Deciphering flavivirus-host interactions using quantitative proteomics. Minghua Li 2020-10-01 Current opinion in immunology
27682269 The Golgi associated ERI3 is a Flavivirus host factor. Michael Alex Ward 2016-09-29 Scientific reports

Transcripts

Name Transcript ID bp Protein Translation ID
ERI3-204 ENST00000456170 1097 202aa ENSP00000390710
ERI3-202 ENST00000372259 1332 222aa ENSP00000361333
ERI3-201 ENST00000372257 1733 337aa ENSP00000361331
ERI3-210 ENST00000649995 1417 315aa ENSP00000497624
ERI3-208 ENST00000489710 394 28aa ENSP00000497761
ERI3-207 ENST00000479101 367 73aa ENSP00000498189
ERI3-206 ENST00000462341 320 No protein -
ERI3-203 ENST00000452396 764 176aa ENSP00000396764
ERI3-209 ENST00000495828 972 No protein -
ERI3-205 ENST00000457571 975 250aa ENSP00000412291

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
14941Hemoglobin A, Glycosylated5.9290000E-00619875614
16034Stroke8.8643251E-00519369658

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000117419homo_sapiensENSP0000025026337.822326.361homo_sapiensENSP0000036133139.169127.2997
ENSG00000117419homo_sapiensENSP0000035065117.076712.0116homo_sapiensENSP0000036133135.014824.6291

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000117419homo_sapiensENSP00000361331100100nomascus_leucogenysENSNLEP00000017052100100
ENSG00000117419homo_sapiensENSP00000361331100100pan_paniscusENSPPAP00000040257100100
ENSG00000117419homo_sapiensENSP00000361331100100pongo_abeliiENSPPYP0000004259168.218668.2186
ENSG00000117419homo_sapiensENSP00000361331100100pan_troglodytesENSPTRP00000001141100100
ENSG00000117419homo_sapiensENSP0000036133186.053484.273gorilla_gorillaENSGGOP0000005035592.356790.4459
ENSG00000117419homo_sapiensENSP0000036133133.827931.1573ornithorhynchus_anatinusENSOANP0000003688271.698166.0377
ENSG00000117419homo_sapiensENSP0000036133121.068218.3976sarcophilus_harrisiiENSSHAP0000003794470.29761.3861
ENSG00000117419homo_sapiensENSP0000036133170.029767.0623notamacropus_eugeniiENSMEUP0000000612780.821977.3973
ENSG00000117419homo_sapiensENSP0000036133166.765666.7656choloepus_hoffmanniENSCHOP0000000962870.312570.3125
ENSG00000117419homo_sapiensENSP0000036133170.623169.1395dasypus_novemcinctusENSDNOP0000001330675.078973.5016
ENSG00000117419homo_sapiensENSP0000036133170.326469.7329echinops_telfairiENSETEP0000001415767.714367.1429
ENSG00000117419homo_sapiensENSP0000036133199.109899.1098callithrix_jacchusENSCJAP0000000733699.701599.7015
ENSG00000117419homo_sapiensENSP0000036133199.703399.7033cercocebus_atysENSCATP0000002337299.703399.7033
ENSG00000117419homo_sapiensENSP0000036133194.065392.8783macaca_fascicularisENSMFAP0000005509487.569186.4641
ENSG00000117419homo_sapiensENSP00000361331100100macaca_mulattaENSMMUP00000015296100100
ENSG00000117419homo_sapiensENSP00000361331100100macaca_nemestrinaENSMNEP00000023951100100
ENSG00000117419homo_sapiensENSP00000361331100100papio_anubisENSPANP00000008444100100
ENSG00000117419homo_sapiensENSP00000361331100100mandrillus_leucophaeusENSMLEP00000003049100100
ENSG00000117419homo_sapiensENSP0000036133190.207789.6142tursiops_truncatusENSTTRP0000001245183.516582.967
ENSG00000117419homo_sapiensENSP0000036133199.109898.8131vulpes_vulpesENSVVUP0000001071972.294472.0779
ENSG00000117419homo_sapiensENSP0000036133198.516397.9229mus_spretusMGP_SPRETEiJ_P006641898.516397.9229
ENSG00000117419homo_sapiensENSP0000036133199.703399.7033equus_asinusENSEASP0000505255872.727372.7273
ENSG00000117419homo_sapiensENSP0000036133194.065392.8783capra_hircusENSCHIP0000002891094.626993.4328
ENSG00000117419homo_sapiensENSP0000036133199.406599.4065loxodonta_africanaENSLAFP0000000258099.406599.4065
ENSG00000117419homo_sapiensENSP0000036133199.109898.8131panthera_leoENSPLOP0000001613299.109898.8131
ENSG00000117419homo_sapiensENSP0000036133199.406599.1098ailuropoda_melanoleucaENSAMEP0000004319899.406599.1098
ENSG00000117419homo_sapiensENSP0000036133194.065392.2849bos_indicus_hybridENSBIXP0000500378068.025766.7382
ENSG00000117419homo_sapiensENSP0000036133193.175192.2849oryctolagus_cuniculusENSOCUP0000004317891.014590.1449
ENSG00000117419homo_sapiensENSP0000036133199.703399.7033equus_caballusENSECAP0000001274072.727372.7273
ENSG00000117419homo_sapiensENSP0000036133199.109898.8131canis_lupus_familiarisENSCAFP0084503792469.583369.375
ENSG00000117419homo_sapiensENSP0000036133132.640929.6736panthera_pardusENSPPRP0000002361778.571471.4286
ENSG00000117419homo_sapiensENSP0000036133199.406599.1098marmota_marmota_marmotaENSMMMP0000000023799.406599.1098
ENSG00000117419homo_sapiensENSP0000036133199.406598.8131balaenoptera_musculusENSBMSP0001001662399.406598.8131
ENSG00000117419homo_sapiensENSP0000036133199.406599.1098cavia_porcellusENSCPOP0000001258199.406599.1098
ENSG00000117419homo_sapiensENSP0000036133199.109898.8131felis_catusENSFCAP0000000489972.294472.0779
ENSG00000117419homo_sapiensENSP0000036133199.406598.8131ursus_americanusENSUAMP0000001024190.785990.2439
ENSG00000117419homo_sapiensENSP0000036133167.655864.3917monodelphis_domesticaENSMODP0000005289991.286.8
ENSG00000117419homo_sapiensENSP0000036133199.109898.5163bison_bison_bisonENSBBBP0000000901199.109898.5163
ENSG00000117419homo_sapiensENSP0000036133199.406598.8131monodon_monocerosENSMMNP0001500800999.406598.8131
ENSG00000117419homo_sapiensENSP0000036133193.768593.4718sus_scrofaENSSSCP0000004742199.684599.3691
ENSG00000117419homo_sapiensENSP0000036133198.813198.8131microcebus_murinusENSMICP0000002258298.813198.8131
ENSG00000117419homo_sapiensENSP0000036133147.477746.8843octodon_degusENSODEP0000002693993.567392.3977
ENSG00000117419homo_sapiensENSP0000036133198.516398.2196octodon_degusENSODEP0000001204898.516398.2196
ENSG00000117419homo_sapiensENSP0000036133198.813198.5163jaculus_jaculusENSJJAP0000000339198.813198.5163
ENSG00000117419homo_sapiensENSP0000036133199.406598.8131ovis_aries_rambouilletENSOARP0002000354868.367367.9592
ENSG00000117419homo_sapiensENSP0000036133195.54994.9555ursus_maritimusENSUMAP0000003374198.470997.8593
ENSG00000117419homo_sapiensENSP0000036133198.813198.8131ochotona_princepsENSOPRP0000000908291.735591.7355
ENSG00000117419homo_sapiensENSP0000036133199.109898.5163delphinapterus_leucasENSDLEP0000001762691.008290.4632
ENSG00000117419homo_sapiensENSP0000036133199.406598.8131physeter_catodonENSPCTP0000502195399.406598.8131
ENSG00000117419homo_sapiensENSP0000036133198.813198.2196mus_caroliMGP_CAROLIEiJ_P006392598.813198.2196
ENSG00000117419homo_sapiensENSP0000036133198.516397.9229mus_musculusENSMUSP0000004279698.516397.9229
ENSG00000117419homo_sapiensENSP0000036133199.109899.1098dipodomys_ordiiENSDORP0000000561199.109899.1098
ENSG00000117419homo_sapiensENSP0000036133173.887273.8872mustela_putorius_furoENSMPUP0000001343698.809598.8095
ENSG00000117419homo_sapiensENSP0000036133199.703399.7033aotus_nancymaaeENSANAP0000001388199.703399.7033
ENSG00000117419homo_sapiensENSP0000036133189.317589.3175saimiri_boliviensis_boliviensisENSSBOP0000003211899.668999.6689
ENSG00000117419homo_sapiensENSP0000036133163.204762.6113vicugna_pacosENSVPAP0000000682658.356257.8082
ENSG00000117419homo_sapiensENSP0000036133110099.7033chlorocebus_sabaeusENSCSAP0000001681610099.7033
ENSG00000117419homo_sapiensENSP0000036133170.919970.9199tupaia_belangeriENSTBEP0000000659690.530390.5303
ENSG00000117419homo_sapiensENSP0000036133198.516397.9229mesocricetus_auratusENSMAUP0000000677198.516397.9229
ENSG00000117419homo_sapiensENSP0000036133199.406598.8131phocoena_sinusENSPSNP0000000513199.406598.8131
ENSG00000117419homo_sapiensENSP0000036133199.406599.1098camelus_dromedariusENSCDRP0000501835999.406599.1098
ENSG00000117419homo_sapiensENSP0000036133176.557974.7775carlito_syrichtaENSTSYP0000000230092.805890.6475
ENSG00000117419homo_sapiensENSP0000036133199.109898.8131panthera_tigris_altaicaENSPTIP0000000402099.109898.8131
ENSG00000117419homo_sapiensENSP0000036133170.326468.2493rattus_norvegicusENSRNOP0000006572182.006979.5848
ENSG00000117419homo_sapiensENSP0000036133199.109897.9229prolemur_simusENSPSMP0000000513399.109897.9229
ENSG00000117419homo_sapiensENSP0000036133198.813198.2196microtus_ochrogasterENSMOCP0000002215698.813198.2196
ENSG00000117419homo_sapiensENSP0000036133181.305680.1187sorex_araneusENSSARP0000001074281.79180.597
ENSG00000117419homo_sapiensENSP0000036133198.813198.2196peromyscus_maniculatus_bairdiiENSPEMP0000002852998.813198.2196
ENSG00000117419homo_sapiensENSP0000036133194.36292.2849bos_mutusENSBMUP0000002205077.941276.2255
ENSG00000117419homo_sapiensENSP0000036133198.516397.9229mus_spicilegusENSMSIP0000001730271.861571.4286
ENSG00000117419homo_sapiensENSP0000036133198.813198.5163cricetulus_griseus_chok1gshdENSCGRP0000102710198.813198.5163
ENSG00000117419homo_sapiensENSP0000036133198.516398.2196pteropus_vampyrusENSPVAP0000001445693.785393.5028
ENSG00000117419homo_sapiensENSP0000036133175.667774.7775myotis_lucifugusENSMLUP0000000352495.864794.7368
ENSG00000117419homo_sapiensENSP0000036133165.875463.5015vombatus_ursinusENSVURP0001002480390.243986.9919
ENSG00000117419homo_sapiensENSP0000036133198.813198.5163rhinolophus_ferrumequinumENSRFEP0001001305898.813198.5163
ENSG00000117419homo_sapiensENSP0000036133193.768592.5816neovison_visonENSNVIP0000002341388.76487.6404
ENSG00000117419homo_sapiensENSP0000036133199.406598.8131bos_taurusENSBTAP0000002067172.510872.0779
ENSG00000117419homo_sapiensENSP0000036133198.813198.2196heterocephalus_glaber_femaleENSHGLP0000000132299.40398.806
ENSG00000117419homo_sapiensENSP00000361331100100rhinopithecus_bietiENSRBIP00000043235100100
ENSG00000117419homo_sapiensENSP0000036133199.109898.8131canis_lupus_dingoENSCAFP0002002189572.294472.0779
ENSG00000117419homo_sapiensENSP0000036133199.703399.7033sciurus_vulgarisENSSVLP0000502159399.703399.7033
ENSG00000117419homo_sapiensENSP0000036133166.172163.5015phascolarctos_cinereusENSPCIP0000005406890.650486.9919
ENSG00000117419homo_sapiensENSP0000036133197.922997.9229procavia_capensisENSPCAP0000000599491.666791.6667
ENSG00000117419homo_sapiensENSP0000036133199.109899.1098nannospalax_galiliENSNGAP0000000113899.109899.1098
ENSG00000117419homo_sapiensENSP0000036133199.406598.8131bos_grunniensENSBGRP0000000786099.406598.8131
ENSG00000117419homo_sapiensENSP0000036133199.109898.8131chinchilla_lanigeraENSCLAP0000000817899.109898.8131
ENSG00000117419homo_sapiensENSP0000036133187.240484.8665cervus_hanglu_yarkandensisENSCHYP0000002916385.964983.6257
ENSG00000117419homo_sapiensENSP0000036133143.026740.0593cervus_hanglu_yarkandensisENSCHYP0000000731478.804373.3696
ENSG00000117419homo_sapiensENSP0000036133199.703399.4065catagonus_wagneriENSCWAP0000000502390.080489.8123
ENSG00000117419homo_sapiensENSP0000036133199.109898.8131ictidomys_tridecemlineatusENSSTOP0000000553199.109898.8131
ENSG00000117419homo_sapiensENSP0000036133199.109898.8131otolemur_garnettiiENSOGAP0000000968599.109898.8131
ENSG00000117419homo_sapiensENSP0000036133199.406599.4065cebus_imitatorENSCCAP0000000877399.406599.4065
ENSG00000117419homo_sapiensENSP0000036133199.109898.8131urocitellus_parryiiENSUPAP0001002669599.109898.8131
ENSG00000117419homo_sapiensENSP0000036133199.406598.8131moschus_moschiferusENSMMSP0000000947099.406598.8131
ENSG00000117419homo_sapiensENSP00000361331100100rhinopithecus_roxellanaENSRROP00000025328100100
ENSG00000117419homo_sapiensENSP0000036133199.109898.5163mus_pahariMGP_PahariEiJ_P007902299.109898.5163
ENSG00000117419homo_sapiensENSP0000036133199.109899.1098propithecus_coquereliENSPCOP0000001864699.109899.1098
ENSG00000117419homo_sapiensENSP0000036133139.465929.6736caenorhabditis_elegansM02B7.2a.15037.594
ENSG00000117419homo_sapiensENSP0000036133140.059330.2671caenorhabditis_elegansR02D3.8.150.751938.3459
ENSG00000117419homo_sapiensENSP0000036133122.551918.1009petromyzon_marinusENSPMAP0000000373280.851164.8936
ENSG00000117419homo_sapiensENSP0000036133154.302742.1365eptatretus_burgeriENSEBUP0000002008169.318253.7879
ENSG00000117419homo_sapiensENSP0000036133157.863549.2582callorhinchus_miliiENSCMIP0000002303470.143959.7122
ENSG00000117419homo_sapiensENSP0000036133167.35961.1276xenopus_tropicalisENSXETP0000011591367.35961.1276
ENSG00000117419homo_sapiensENSP0000036133156.973353.7092chrysemys_picta_belliiENSCPBP0000000455468.571464.6429
ENSG00000117419homo_sapiensENSP0000036133170.919967.9525sphenodon_punctatusENSSPUP0000000416092.635788.7597
ENSG00000117419homo_sapiensENSP0000036133158.45753.1157crocodylus_porosusENSCPRP0000502513173.234266.5427
ENSG00000117419homo_sapiensENSP0000036133140.059338.8724laticauda_laticaudataENSLLTP0000001857992.465889.726
ENSG00000117419homo_sapiensENSP0000036133167.952565.8754notechis_scutatusENSNSUP0000002156589.105186.3813
ENSG00000117419homo_sapiensENSP0000036133167.952566.1721pseudonaja_textilisENSPTXP0000000193089.105186.7704
ENSG00000117419homo_sapiensENSP0000036133169.732964.9852anas_platyrhynchos_platyrhynchosENSAPLP0000002539657.739653.8084
ENSG00000117419homo_sapiensENSP0000036133170.623166.4688gallus_gallusENSGALP0001003861792.248186.8217
ENSG00000117419homo_sapiensENSP0000036133164.985260.5341meleagris_gallopavoENSMGAP0000002147188.66482.5911
ENSG00000117419homo_sapiensENSP0000036133170.919967.6558serinus_canariaENSSCAP0000000047392.635788.3721
ENSG00000117419homo_sapiensENSP0000036133171.216668.2493parus_majorENSPMJP0000002676193.023389.1473
ENSG00000117419homo_sapiensENSP0000036133171.216668.2493anolis_carolinensisENSACAP0000001445985.409381.8505
ENSG00000117419homo_sapiensENSP0000036133163.501560.2374naja_najaENSNNAP0000000825072.053968.3502
ENSG00000117419homo_sapiensENSP0000036133169.436266.7656podarcis_muralisENSPMRP0000001511491.406287.8906
ENSG00000117419homo_sapiensENSP0000036133173.590570.6231geospiza_fortisENSGFOP0000001111288.888985.3047
ENSG00000117419homo_sapiensENSP0000036133175.370971.8101taeniopygia_guttataENSTGUP0000003777082.736278.8274
ENSG00000117419homo_sapiensENSP0000036133155.192946.2908erpetoichthys_calabaricusENSECRP0000001344772.656260.9375
ENSG00000117419homo_sapiensENSP0000036133171.216668.2493salvator_merianaeENSSMRP0000002371280.808177.4411
ENSG00000117419homo_sapiensENSP0000036133148.071245.4006pelodiscus_sinensisENSPSIP0000000694279.024474.6341
ENSG00000117419homo_sapiensENSP0000036133168.54666.1721gopherus_evgoodeiENSGEVP0000501588289.534986.4341
ENSG00000117419homo_sapiensENSP0000036133168.54666.1721chelonoidis_abingdoniiENSCABP0000000855089.534986.4341
ENSG00000117419homo_sapiensENSP0000036133164.688461.4243struthio_camelus_australisENSSCUP0000001629487.903283.4677
ENSG00000117419homo_sapiensENSP0000036133163.798260.2374anser_brachyrhynchusENSABRP0000002104788.114883.1967
ENSG00000117419homo_sapiensENSP0000036133174.480770.6231strigops_habroptilaENSSHBP0000501746690.287885.6115
ENSG00000117419homo_sapiensENSP0000036133168.54666.1721terrapene_carolina_triunguisENSTMTP0000000241589.534986.4341
ENSG00000117419homo_sapiensENSP0000036133170.919967.9525aquila_chrysaetos_chrysaetosENSACCP0002001143192.635788.7597
ENSG00000117419homo_sapiensENSP0000036133173.293870.3264ficedula_albicollisENSFALP0000001705488.530584.9462
ENSG00000117419homo_sapiensENSP0000036133176.557971.2166coturnix_japonicaENSCJPP0000501133072.268967.2269
ENSG00000117419homo_sapiensENSP0000036133159.347251.632leptobrachium_leishanenseENSLLEP0000004404737.453232.5843

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000175enables 3-5-RNA exonuclease activity1IBAHomo_sapiens(9606)Function
GO:0000467involved_in exonucleolytic trimming to generate mature 3-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)1IBAHomo_sapiens(9606)Process
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0046872enables metal ion binding1IEAHomo_sapiens(9606)Function

Expression