Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer Disease
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions Transmemebrane
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000116688 Gene ID 9927 Accession 16877
Symbol MFN2 Alias HSG;MSL;MARF;CMT2A;CPRP1;CMT2A2;HMSN6A;CMT2A2A;CMT2A2B Full Name mitofusin 2
Status Confidence Length 35031 bases Strand Plus strand
Position 1 : 11980181 - 12015211 RNA binding domain MMR_HSR1
Summary This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000235329 MMR_HSR1 PF01926 9.1e-07 1
ENSP00000416338 MMR_HSR1 PF01926 9.1e-07 1
ENSP00000501646 MMR_HSR1 PF01926 9.1e-07 1
ENSP00000501716 MMR_HSR1 PF01926 9.1e-07 1
ENSP00000501776 MMR_HSR1 PF01926 9.1e-07 1
ENSP00000502151 MMR_HSR1 PF01926 9.1e-07 1
ENSP00000502185 MMR_HSR1 PF01926 9.1e-07 1
ENSP00000502362 MMR_HSR1 PF01926 9.1e-07 1
ENSP00000502404 MMR_HSR1 PF01926 9.1e-07 1
ENSP00000502623 MMR_HSR1 PF01926 9.1e-07 1
ENSP00000502145 MMR_HSR1 PF01926 1.1e-06 1
ENSP00000501839 MMR_HSR1 PF01926 1.2e-06 1
ENSP00000502422 MMR_HSR1 PF01926 1.3e-06 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
36567017 Mitochondria-localized lncRNA HITT inhibits fusion by attenuating formation of mitofusin-2 homotypic or heterotypic complexes. Xingwen Wang 2023-02-01 The Journal of biological chemistry
29363649 Role of the Ca2+-Calcineurin-Nuclear Factor of Activated T cell Pathway in Mitofusin-2-Mediated Immune Function of Jurkat Cells. Xiu-Ping Xu 2018-02-05 Chinese medical journal

Transcripts

Name Transcript ID bp Protein Translation ID
MFN2-203 ENST00000444836 4531 757aa ENSP00000416338
MFN2-210 ENST00000674817 4514 757aa ENSP00000502151
MFN2-213 ENST00000675053 4555 757aa ENSP00000501646
MFN2-215 ENST00000675194 2944 No protein -
MFN2-225 ENST00000675817 4766 801aa ENSP00000502422
MFN2-217 ENST00000675298 3584 808aa ENSP00000501839
MFN2-232 ENST00000676369 781 98aa ENSP00000502005
MFN2-202 ENST00000412236 777 98aa ENSP00000412023
MFN2-223 ENST00000675530 709 98aa ENSP00000501972
MFN2-207 ENST00000674548 4572 757aa ENSP00000502185
MFN2-228 ENST00000675959 4715 No protein -
MFN2-226 ENST00000675872 4569 No protein -
MFN2-209 ENST00000674706 2005 No protein -
MFN2-233 ENST00000676426 4352 255aa ENSP00000502359
MFN2-208 ENST00000674658 4320 642aa ENSP00000502334
MFN2-211 ENST00000674910 4539 757aa ENSP00000501716
MFN2-205 ENST00000490079 445 No protein -
MFN2-216 ENST00000675231 4772 757aa ENSP00000502404
MFN2-204 ENST00000484391 294 No protein -
MFN2-206 ENST00000497302 645 60aa ENSP00000502511
MFN2-221 ENST00000675512 4580 60aa ENSP00000502630
MFN2-214 ENST00000675113 4461 757aa ENSP00000502623
MFN2-201 ENST00000235329 4407 757aa ENSP00000235329
MFN2-230 ENST00000676293 4529 757aa ENSP00000502362
MFN2-227 ENST00000675919 4497 757aa ENSP00000501776
MFN2-229 ENST00000675987 4453 690aa ENSP00000502145
MFN2-224 ENST00000675781 563 71aa ENSP00000501947
MFN2-220 ENST00000675483 4337 No protein -
MFN2-218 ENST00000675374 583 No protein -
MFN2-222 ENST00000675528 3700 No protein -
MFN2-219 ENST00000675404 4447 No protein -
MFN2-231 ENST00000676295 2622 No protein -
MFN2-212 ENST00000675043 2148 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
13815Myocardial Infarction8.9703528E-004-
62559Platelet Count1E-822139419
83732Dermatitis, Atopic1E-625574825

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000116688homo_sapiensENSP0000042061780.836763.0229homo_sapiensENSP0000023532979.128161.6909

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000116688homo_sapiensENSP0000023532994.451893.395nomascus_leucogenysENSNLEP0000001188999.030597.9224
ENSG00000116688homo_sapiensENSP0000023532910099.7358pan_paniscusENSPPAP0000000984010099.7358
ENSG00000116688homo_sapiensENSP0000023532910099.7358pongo_abeliiENSPPYP0000003885510099.7358
ENSG00000116688homo_sapiensENSP0000023532910099.7358pan_troglodytesENSPTRP0000000030510099.7358
ENSG00000116688homo_sapiensENSP0000023532910099.7358gorilla_gorillaENSGGOP0000000513210099.7358
ENSG00000116688homo_sapiensENSP0000023532996.03792.4703ornithorhynchus_anatinusENSOANP0000004359196.03792.4703
ENSG00000116688homo_sapiensENSP0000023532997.093892.6024sarcophilus_harrisiiENSSHAP0000003276397.093892.6024
ENSG00000116688homo_sapiensENSP0000023532961.558857.5958notamacropus_eugeniiENSMEUP0000000309461.558857.5958
ENSG00000116688homo_sapiensENSP0000023532979.788677.675choloepus_hoffmanniENSCHOP000000090368077.8808
ENSG00000116688homo_sapiensENSP0000023532999.075396.5654dasypus_novemcinctusENSDNOP0000000978999.075396.5654
ENSG00000116688homo_sapiensENSP0000023532973.579971.5984erinaceus_europaeusENSEEUP0000000304073.482871.504
ENSG00000116688homo_sapiensENSP0000023532987.450584.2801echinops_telfairiENSETEP0000000324387.798484.6154
ENSG00000116688homo_sapiensENSP0000023532999.735899.4716callithrix_jacchusENSCJAP0000009031191.183690.942
ENSG00000116688homo_sapiensENSP0000023532910099.6037cercocebus_atysENSCATP0000000989510099.6037
ENSG00000116688homo_sapiensENSP0000023532998.018597.4901macaca_fascicularisENSMFAP0000002734495.741995.2258
ENSG00000116688homo_sapiensENSP0000023532910099.6037macaca_mulattaENSMMUP0000004642010099.6037
ENSG00000116688homo_sapiensENSP0000023532910099.3395macaca_nemestrinaENSMNEP0000004434110099.3395
ENSG00000116688homo_sapiensENSP0000023532910099.6037papio_anubisENSPANP0000000365110099.6037
ENSG00000116688homo_sapiensENSP0000023532996.301295.1123mandrillus_leucophaeusENSMLEP0000002668397.721296.5147
ENSG00000116688homo_sapiensENSP0000023532999.075396.5654tursiops_truncatusENSTTRP0000000329199.075396.5654
ENSG00000116688homo_sapiensENSP0000023532998.943297.358vulpes_vulpesENSVVUP0000004002398.943297.358
ENSG00000116688homo_sapiensENSP0000023532998.67995.2444mus_spretusMGP_SPRETEiJ_P006829798.67995.2444
ENSG00000116688homo_sapiensENSP0000023532999.207497.2259equus_asinusENSEASP0000502427299.207497.2259
ENSG00000116688homo_sapiensENSP0000023532998.943296.3012capra_hircusENSCHIP0000001599498.943296.3012
ENSG00000116688homo_sapiensENSP0000023532999.207497.0938loxodonta_africanaENSLAFP0000000032199.207497.0938
ENSG00000116688homo_sapiensENSP0000023532999.207497.0938panthera_leoENSPLOP0000000900199.207497.0938
ENSG00000116688homo_sapiensENSP0000023532999.207497.358ailuropoda_melanoleucaENSAMEP0000001061499.207497.358
ENSG00000116688homo_sapiensENSP0000023532999.075396.8296bos_indicus_hybridENSBIXP0000501782299.075396.8296
ENSG00000116688homo_sapiensENSP0000023532995.376592.8666oryctolagus_cuniculusENSOCUP0000000689398.768896.1696
ENSG00000116688homo_sapiensENSP0000023532999.075396.9617equus_caballusENSECAP0000001434599.075396.9617
ENSG00000116688homo_sapiensENSP0000023532998.943297.358canis_lupus_familiarisENSCAFP0084500246298.943297.358
ENSG00000116688homo_sapiensENSP0000023532999.207497.0938panthera_pardusENSPPRP0000001419699.207497.0938
ENSG00000116688homo_sapiensENSP0000023532999.207496.9617marmota_marmota_marmotaENSMMMP0000001874999.207496.9617
ENSG00000116688homo_sapiensENSP0000023532998.67996.3012balaenoptera_musculusENSBMSP0001000984998.67996.3012
ENSG00000116688homo_sapiensENSP0000023532998.811196.5654cavia_porcellusENSCPOP0000003297098.811196.5654
ENSG00000116688homo_sapiensENSP0000023532999.075397.0938felis_catusENSFCAP0000002716599.075397.0938
ENSG00000116688homo_sapiensENSP0000023532999.075397.0938ursus_americanusENSUAMP0000001285799.075397.0938
ENSG00000116688homo_sapiensENSP0000023532996.961792.3382monodelphis_domesticaENSMODP0000005202496.961792.3382
ENSG00000116688homo_sapiensENSP0000023532999.075396.8296bison_bison_bisonENSBBBP0000002645499.075396.8296
ENSG00000116688homo_sapiensENSP0000023532998.811196.3012monodon_monocerosENSMMNP0001500877098.811196.3012
ENSG00000116688homo_sapiensENSP0000023532998.414896.3012sus_scrofaENSSSCP0000005722298.414896.3012
ENSG00000116688homo_sapiensENSP0000023532997.622295.6407microcebus_murinusENSMICP0000004436497.36595.3887
ENSG00000116688homo_sapiensENSP0000023532999.075396.5654octodon_degusENSODEP0000002082599.075396.5654
ENSG00000116688homo_sapiensENSP0000023532998.67995.9049jaculus_jaculusENSJJAP0000000766998.67995.9049
ENSG00000116688homo_sapiensENSP0000023532998.943296.3012ovis_aries_rambouilletENSOARP0002001424893.742291.2391
ENSG00000116688homo_sapiensENSP0000023532998.943296.9617ursus_maritimusENSUMAP0000003065198.943296.9617
ENSG00000116688homo_sapiensENSP0000023532996.433394.0555ochotona_princepsENSOPRP0000000624196.688794.3046
ENSG00000116688homo_sapiensENSP0000023532998.811196.3012delphinapterus_leucasENSDLEP0000002377098.811196.3012
ENSG00000116688homo_sapiensENSP0000023532998.282795.5086physeter_catodonENSPCTP0000502198698.282795.5086
ENSG00000116688homo_sapiensENSP0000023532998.67995.2444mus_caroliMGP_CAROLIEiJ_P006572198.67995.2444
ENSG00000116688homo_sapiensENSP0000023532998.811194.9802mus_musculusENSMUSP0000003088498.811194.9802
ENSG00000116688homo_sapiensENSP0000023532998.811196.5654mustela_putorius_furoENSMPUP0000001628598.811196.5654
ENSG00000116688homo_sapiensENSP0000023532999.735899.2074aotus_nancymaaeENSANAP0000001585899.735899.2074
ENSG00000116688homo_sapiensENSP0000023532999.603799.3395saimiri_boliviensis_boliviensisENSSBOP0000003165399.603799.3395
ENSG00000116688homo_sapiensENSP0000023532965.389764.2008vicugna_pacosENSVPAP0000000258271.018769.7274
ENSG00000116688homo_sapiensENSP0000023532910099.6037chlorocebus_sabaeusENSCSAP0000001720010099.6037
ENSG00000116688homo_sapiensENSP0000023532973.71272.391tupaia_belangeriENSTBEP0000000330179.714378.2857
ENSG00000116688homo_sapiensENSP0000023532999.207495.6407mesocricetus_auratusENSMAUP0000000684399.207495.6407
ENSG00000116688homo_sapiensENSP0000023532999.075396.6975phocoena_sinusENSPSNP0000001630797.529395.1886
ENSG00000116688homo_sapiensENSP0000023532998.811196.8296camelus_dromedariusENSCDRP0000502587898.811196.8296
ENSG00000116688homo_sapiensENSP0000023532998.811197.0938carlito_syrichtaENSTSYP0000002094498.811197.0938
ENSG00000116688homo_sapiensENSP0000023532999.207497.0938panthera_tigris_altaicaENSPTIP0000002361499.207497.0938
ENSG00000116688homo_sapiensENSP0000023532998.546995.2444rattus_norvegicusENSRNOP0000005253997.009193.7581
ENSG00000116688homo_sapiensENSP0000023532999.471697.6222prolemur_simusENSPSMP0000002026299.471697.6222
ENSG00000116688homo_sapiensENSP0000023532999.207496.4333microtus_ochrogasterENSMOCP0000002126499.207496.4333
ENSG00000116688homo_sapiensENSP0000023532957.331655.3501sorex_araneusENSSARP0000001129457.180555.2042
ENSG00000116688homo_sapiensENSP0000023532999.339596.4333peromyscus_maniculatus_bairdiiENSPEMP0000002297799.339596.4333
ENSG00000116688homo_sapiensENSP0000023532999.075396.8296bos_mutusENSBMUP0000001713499.075396.8296
ENSG00000116688homo_sapiensENSP0000023532998.67995.2444mus_spicilegusENSMSIP0000001277298.67995.2444
ENSG00000116688homo_sapiensENSP0000023532999.207496.037cricetulus_griseus_chok1gshdENSCGRP0000101044699.207496.037
ENSG00000116688homo_sapiensENSP0000023532994.583992.074pteropus_vampyrusENSPVAP0000000143294.459191.9525
ENSG00000116688homo_sapiensENSP0000023532997.754395.7728myotis_lucifugusENSMLUP0000001156097.754395.7728
ENSG00000116688homo_sapiensENSP0000023532996.697592.2061vombatus_ursinusENSVURP0001003137896.697592.2061
ENSG00000116688homo_sapiensENSP0000023532998.67995.9049rhinolophus_ferrumequinumENSRFEP0001002610398.67995.9049
ENSG00000116688homo_sapiensENSP0000023532998.811196.5654neovison_visonENSNVIP0000001346798.811196.5654
ENSG00000116688homo_sapiensENSP0000023532999.075396.8296bos_taurusENSBTAP0000007084199.075396.8296
ENSG00000116688homo_sapiensENSP0000023532998.67996.5654heterocephalus_glaber_femaleENSHGLP0000001627296.13994.0798
ENSG00000116688homo_sapiensENSP0000023532999.867999.4716rhinopithecus_bietiENSRBIP0000004182099.867999.4716
ENSG00000116688homo_sapiensENSP0000023532998.943297.2259canis_lupus_dingoENSCAFP0002001124598.943297.2259
ENSG00000116688homo_sapiensENSP0000023532999.075396.6975sciurus_vulgarisENSSVLP0000500830699.075396.6975
ENSG00000116688homo_sapiensENSP0000023532996.301291.2814phascolarctos_cinereusENSPCIP0000004138896.428691.4021
ENSG00000116688homo_sapiensENSP0000023532993.923491.5456procavia_capensisENSPCAP0000001309393.923491.5456
ENSG00000116688homo_sapiensENSP0000023532999.075396.1691nannospalax_galiliENSNGAP0000001280699.075396.1691
ENSG00000116688homo_sapiensENSP0000023532999.075396.8296bos_grunniensENSBGRP0000001325694.458492.3174
ENSG00000116688homo_sapiensENSP0000023532999.075396.6975chinchilla_lanigeraENSCLAP0000001344199.075396.6975
ENSG00000116688homo_sapiensENSP0000023532999.075396.6975cervus_hanglu_yarkandensisENSCHYP0000003468799.075396.6975
ENSG00000116688homo_sapiensENSP0000023532998.282796.1691catagonus_wagneriENSCWAP0000000883998.282796.1691
ENSG00000116688homo_sapiensENSP0000023532999.207497.2259ictidomys_tridecemlineatusENSSTOP0000002989699.207497.2259
ENSG00000116688homo_sapiensENSP0000023532999.471697.4901otolemur_garnettiiENSOGAP0000000478999.471697.4901
ENSG00000116688homo_sapiensENSP0000023532999.735899.4716cebus_imitatorENSCCAP0000001806799.735899.4716
ENSG00000116688homo_sapiensENSP0000023532999.207496.9617urocitellus_parryiiENSUPAP0001000471999.207496.9617
ENSG00000116688homo_sapiensENSP0000023532998.943296.4333moschus_moschiferusENSMMSP0000002315098.943296.4333
ENSG00000116688homo_sapiensENSP0000023532993.130892.7345rhinopithecus_roxellanaENSRROP0000001748710099.5745
ENSG00000116688homo_sapiensENSP0000023532998.67994.9802mus_pahariMGP_PahariEiJ_P008082998.67994.9802
ENSG00000116688homo_sapiensENSP0000023532999.339597.6222propithecus_coquereliENSPCOP0000000352799.339597.6222
ENSG00000116688homo_sapiensENSP0000023532956.935335.9313caenorhabditis_elegansZK1248.14.155.684835.1421
ENSG00000116688homo_sapiensENSP0000023532967.371247.2919drosophila_melanogasterFBpp031003062.653643.9803
ENSG00000116688homo_sapiensENSP0000023532952.57633.1572drosophila_melanogasterFBpp008379155.431834.9582
ENSG00000116688homo_sapiensENSP0000023532968.824350.9908ciona_intestinalisENSCINP0000001394268.462550.7227
ENSG00000116688homo_sapiensENSP0000023532969.220658.1242eptatretus_burgeriENSEBUP0000002416482.260669.0738
ENSG00000116688homo_sapiensENSP0000023532989.960481.5059callorhinchus_miliiENSCMIP0000001428392.02783.3784
ENSG00000116688homo_sapiensENSP0000023532993.923485.0727latimeria_chalumnaeENSLACP0000000582593.923485.0727
ENSG00000116688homo_sapiensENSP0000023532992.206184.1479lepisosteus_oculatusENSLOCP0000000650192.32884.2593
ENSG00000116688homo_sapiensENSP0000023532991.941984.1479clupea_harengusENSCHAP0000000031691.578983.8158
ENSG00000116688homo_sapiensENSP0000023532991.941982.959danio_rerioENSDARP0000012328591.941982.959
ENSG00000116688homo_sapiensENSP0000023532964.729256.539carassius_auratusENSCARP0000012567386.879475.8865
ENSG00000116688homo_sapiensENSP0000023532992.206182.827carassius_auratusENSCARP0000012626192.206182.827
ENSG00000116688homo_sapiensENSP0000023532991.545682.959astyanax_mexicanusENSAMXP0000001445589.650781.2419
ENSG00000116688homo_sapiensENSP0000023532991.545682.959ictalurus_punctatusENSIPUP0000003043391.545682.959
ENSG00000116688homo_sapiensENSP0000023532991.809884.2801esox_luciusENSELUP0000005752691.207483.727
ENSG00000116688homo_sapiensENSP0000023532992.206183.4874electrophorus_electricusENSEEEP0000000242592.206183.4874
ENSG00000116688homo_sapiensENSP0000023532991.149383.7516oncorhynchus_kisutchENSOKIP0000505321090.551283.2021
ENSG00000116688homo_sapiensENSP0000023532991.149383.7516oncorhynchus_mykissENSOMYP0000005276390.078382.7676
ENSG00000116688homo_sapiensENSP0000023532989.167881.7701salmo_salarENSSSAP0000002141187.096879.871
ENSG00000116688homo_sapiensENSP0000023532989.299981.638salmo_truttaENSSTUP0000003352088.36680.7843
ENSG00000116688homo_sapiensENSP0000023532992.206183.3553gadus_morhuaENSGMOP0000000353892.084483.2454
ENSG00000116688homo_sapiensENSP0000023532989.299980.9775fundulus_heteroclitusENSFHEP0000001002889.182180.8707
ENSG00000116688homo_sapiensENSP0000023532989.564180.0528poecilia_reticulataENSPREP0000001258289.445979.9472
ENSG00000116688homo_sapiensENSP0000023532989.299979.6565xiphophorus_maculatusENSXMAP0000000466389.182179.5515
ENSG00000116688homo_sapiensENSP0000023532990.620981.5059oryzias_latipesENSORLP0000002637090.620981.5059
ENSG00000116688homo_sapiensENSP0000023532989.564179.6565oreochromis_niloticusENSONIP0000002938385.175975.7538
ENSG00000116688homo_sapiensENSP0000023532991.677782.2985haplochromis_burtoniENSHBUP0000000316391.436182.0817
ENSG00000116688homo_sapiensENSP0000023532991.545682.2985astatotilapia_callipteraENSACLP0000000665491.304382.0817
ENSG00000116688homo_sapiensENSP0000023532991.941984.1479sparus_aurataENSSAUP0001000442191.820684.0369
ENSG00000116688homo_sapiensENSP0000023532991.941983.7516lates_calcariferENSLCAP0001001653791.218983.0931
ENSG00000116688homo_sapiensENSP0000023532992.866685.469xenopus_tropicalisENSXETP0000008050392.989485.582
ENSG00000116688homo_sapiensENSP0000023532996.961792.6024chrysemys_picta_belliiENSCPBP0000003127496.961792.6024
ENSG00000116688homo_sapiensENSP0000023532995.376590.0925sphenodon_punctatusENSSPUP0000001630395.376590.0925
ENSG00000116688homo_sapiensENSP0000023532996.565491.4135crocodylus_porosusENSCPRP0000501993596.057890.933
ENSG00000116688homo_sapiensENSP0000023532985.072776.0898laticauda_laticaudataENSLLTP0000001197783.963575.0978
ENSG00000116688homo_sapiensENSP0000023532990.75383.2233pseudonaja_textilisENSPTXP0000001738294.238786.4198
ENSG00000116688homo_sapiensENSP0000023532994.187689.432anas_platyrhynchos_platyrhynchosENSAPLP0000001229297.006892.1088
ENSG00000116688homo_sapiensENSP0000023532996.301291.2814gallus_gallusENSGALP0001002485996.556391.5232
ENSG00000116688homo_sapiensENSP0000023532996.301291.4135meleagris_gallopavoENSMGAP0000000605296.556391.6556
ENSG00000116688homo_sapiensENSP0000023532996.301291.2814serinus_canariaENSSCAP0000000364396.556391.5232
ENSG00000116688homo_sapiensENSP0000023532996.301291.4135parus_majorENSPMJP0000001209096.556391.6556
ENSG00000116688homo_sapiensENSP0000023532959.973652.1797anolis_carolinensisENSACAP0000003636783.609672.744
ENSG00000116688homo_sapiensENSP0000023532991.677782.5627neolamprologus_brichardiENSNBRP0000002824791.436182.3452
ENSG00000116688homo_sapiensENSP0000023532995.376587.9789naja_najaENSNNAP0000001775495.376587.9789
ENSG00000116688homo_sapiensENSP0000023532988.375280.7133podarcis_muralisENSPMRP0000002081392.787884.7434
ENSG00000116688homo_sapiensENSP0000023532996.301291.4135geospiza_fortisENSGFOP0000001533696.556391.6556
ENSG00000116688homo_sapiensENSP0000023532996.169191.6777taeniopygia_guttataENSTGUP0000000252295.789591.3158
ENSG00000116688homo_sapiensENSP0000023532992.602483.4874erpetoichthys_calabaricusENSECRP0000000914992.602483.4874
ENSG00000116688homo_sapiensENSP0000023532976.486167.7675kryptolebias_marmoratusENSKMAP0000001844486.417976.5672
ENSG00000116688homo_sapiensENSP0000023532995.376589.6962salvator_merianaeENSSMRP0000002028895.376589.6962
ENSG00000116688homo_sapiensENSP0000023532990.75382.1664oryzias_javanicusENSOJAP0000000175390.75382.1664
ENSG00000116688homo_sapiensENSP0000023532988.11179.1281amphilophus_citrinellusENSACIP0000001773990.748381.4966
ENSG00000116688homo_sapiensENSP0000023532991.545683.8838dicentrarchus_labraxENSDLAP0000502915287.944280.5838
ENSG00000116688homo_sapiensENSP0000023532991.149383.6196amphiprion_perculaENSAPEP0000002084589.378281.9948
ENSG00000116688homo_sapiensENSP0000023532996.565492.6024pelodiscus_sinensisENSPSIP0000001180896.565492.6024
ENSG00000116688homo_sapiensENSP0000023532997.225993.1308gopherus_evgoodeiENSGEVP0000501140397.225993.1308
ENSG00000116688homo_sapiensENSP0000023532997.225992.6024chelonoidis_abingdoniiENSCABP0000002337997.225992.6024
ENSG00000116688homo_sapiensENSP0000023532985.997478.8639seriola_dumeriliENSSDUP0000000114891.561283.9662
ENSG00000116688homo_sapiensENSP0000023532990.620982.5627cottoperca_gobioENSCGOP0000001095990.382182.3452
ENSG00000116688homo_sapiensENSP0000023532993.791388.9036struthio_camelus_australisENSSCUP0000000926793.667588.7863
ENSG00000116688homo_sapiensENSP0000023532996.433391.5456anser_brachyrhynchusENSABRP0000002386596.179291.3043
ENSG00000116688homo_sapiensENSP0000023532991.677783.0911gasterosteus_aculeatusENSGACP0000001701091.556782.9815
ENSG00000116688homo_sapiensENSP0000023532991.413582.827cynoglossus_semilaevisENSCSEP0000000722891.172682.6087
ENSG00000116688homo_sapiensENSP0000023532989.696279.9207poecilia_formosaENSPFOP0000001723789.577879.8153
ENSG00000116688homo_sapiensENSP0000023532992.338283.4874myripristis_murdjanENSMMDP0000504463192.216483.3773
ENSG00000116688homo_sapiensENSP0000023532991.677782.959sander_luciopercaENSSLUP0000005408486.533778.3042
ENSG00000116688homo_sapiensENSP0000023532996.169191.8098strigops_habroptilaENSSHBP0000500678296.423892.053
ENSG00000116688homo_sapiensENSP0000023532991.149383.6196amphiprion_ocellarisENSAOCP0000002211091.02983.5092
ENSG00000116688homo_sapiensENSP0000023532997.225992.6024terrapene_carolina_triunguisENSTMTP0000003034897.225992.6024
ENSG00000116688homo_sapiensENSP0000023532991.149383.7516hucho_huchoENSHHUP0000008013190.551283.2021
ENSG00000116688homo_sapiensENSP0000023532988.507379.9207betta_splendensENSBSLP0000005210490.418481.6464
ENSG00000116688homo_sapiensENSP0000023532991.809884.2801pygocentrus_nattereriENSPNAP0000003635091.809884.2801
ENSG00000116688homo_sapiensENSP0000023532986.393776.4861anabas_testudineusENSATEP0000005096586.16676.2846
ENSG00000116688homo_sapiensENSP0000023532968.824351.255ciona_savignyiENSCSAVP0000001799668.64351.1199
ENSG00000116688homo_sapiensENSP0000023532940.026419.9472saccharomyces_cerevisiaeYBR179C35.438617.6608
ENSG00000116688homo_sapiensENSP0000023532989.43282.0343seriola_lalandi_dorsalisENSSLDP0000003215292.739785.0685
ENSG00000116688homo_sapiensENSP0000023532991.941984.1479labrus_bergyltaENSLBEP0000001593891.820684.0369
ENSG00000116688homo_sapiensENSP0000023532989.828380.8454pundamilia_nyerereiENSPNYP0000003197292.140982.9268
ENSG00000116688homo_sapiensENSP0000023532991.413582.827mastacembelus_armatusENSMAMP0000004440891.292982.7177
ENSG00000116688homo_sapiensENSP0000023532991.677783.3553stegastes_partitusENSSPAP0000001224091.556783.2454
ENSG00000116688homo_sapiensENSP0000023532989.167881.5059oncorhynchus_tshawytschaENSOTSP0000506110788.699181.0775
ENSG00000116688homo_sapiensENSP0000023532989.167881.5059oncorhynchus_tshawytschaENSOTSP0000507917388.699181.0775
ENSG00000116688homo_sapiensENSP0000023532984.940678.0713acanthochromis_polyacanthusENSAPOP0000003075590.947783.5926
ENSG00000116688homo_sapiensENSP0000023532996.301291.5456aquila_chrysaetos_chrysaetosENSACCP0002002097496.556391.7881
ENSG00000116688homo_sapiensENSP0000023532987.582677.5429nothobranchius_furzeriENSNFUP0001503559185.328275.547
ENSG00000116688homo_sapiensENSP0000023532989.299980.4491cyprinodon_variegatusENSCVAP0000002609588.481779.712
ENSG00000116688homo_sapiensENSP0000023532990.356782.1664denticeps_clupeoidesENSDCDP0000003095689.411881.3072
ENSG00000116688homo_sapiensENSP0000023532991.941984.1479larimichthys_croceaENSLCRP0000505904786.459679.1304
ENSG00000116688homo_sapiensENSP0000023532983.355373.712takifugu_rubripesENSTRUP0000005877888.873278.5916
ENSG00000116688homo_sapiensENSP0000023532990.75381.638takifugu_rubripesENSTRUP0000001869889.803980.7843
ENSG00000116688homo_sapiensENSP0000023532996.169191.1493ficedula_albicollisENSFALP0000001043596.423891.3907
ENSG00000116688homo_sapiensENSP0000023532990.75381.9022hippocampus_comesENSHCOP0000002412190.633281.7942
ENSG00000116688homo_sapiensENSP0000023532991.545682.4306cyprinus_carpio_carpioENSCCRP0000012347390.234481.25
ENSG00000116688homo_sapiensENSP0000023532991.941982.4306cyprinus_carpio_carpioENSCCRP0000013781688.888979.6935
ENSG00000116688homo_sapiensENSP0000023532996.169191.1493coturnix_japonicaENSCJPP0000500675494.300589.3782
ENSG00000116688homo_sapiensENSP0000023532981.241772.391poecilia_latipinnaENSPLAP0000002921989.912380.117
ENSG00000116688homo_sapiensENSP0000023532969.220660.6341sinocyclocheilus_grahamiENSSGRP0000005947083.572673.2057
ENSG00000116688homo_sapiensENSP0000023532931.968329.1942sinocyclocheilus_grahamiENSSGRP0000001882480.398773.4219
ENSG00000116688homo_sapiensENSP0000023532991.677781.7701sinocyclocheilus_grahamiENSSGRP0000002079891.677781.7701
ENSG00000116688homo_sapiensENSP0000023532991.545682.2985maylandia_zebraENSMZEP0000502490291.304382.0817
ENSG00000116688homo_sapiensENSP0000023532991.545683.2233tetraodon_nigroviridisENSTNIP0000000699191.424883.1135
ENSG00000116688homo_sapiensENSP0000023532992.602483.3553paramormyrops_kingsleyaeENSPKIP0000003463892.602483.3553
ENSG00000116688homo_sapiensENSP0000023532992.866683.4874scleropages_formosusENSSFOP0001501622192.866683.4874
ENSG00000116688homo_sapiensENSP0000023532994.055584.9406leptobrachium_leishanenseENSLLEP0000003972593.931484.8285
ENSG00000116688homo_sapiensENSP0000023532991.149382.6948scophthalmus_maximusENSSMAP0000000517190.078381.7232
ENSG00000116688homo_sapiensENSP0000023532988.639480.7133oryzias_melastigmaENSOMEP0000002159992.043983.8134

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0001825involved_in blastocyst formation1IEAHomo_sapiens(9606)Process
GO:0003924enables GTPase activity1IBAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005525enables GTP binding1IEAHomo_sapiens(9606)Function
GO:0005739located_in mitochondrion1IDAHomo_sapiens(9606)Component
GO:0005741located_in mitochondrial outer membrane2ISS,TASHomo_sapiens(9606)Component
GO:0005829located_in cytosol1ISSHomo_sapiens(9606)Component
GO:0006626involved_in protein targeting to mitochondrion1IDAHomo_sapiens(9606)Process
GO:0006915involved_in apoptotic process1IEAHomo_sapiens(9606)Process
GO:0006986involved_in response to unfolded protein1IEAHomo_sapiens(9606)Process
GO:0007006involved_in mitochondrial membrane organization1IDAHomo_sapiens(9606)Process
GO:0008053involved_in mitochondrial fusion4IBA,IMP,ISS,NASHomo_sapiens(9606)Process
GO:0015630located_in microtubule cytoskeleton1IEAHomo_sapiens(9606)Component
GO:0031625enables ubiquitin protein ligase binding1IPIHomo_sapiens(9606)Function
GO:0034497acts_upstream_of_or_within protein localization to phagophore assembly site1IDAHomo_sapiens(9606)Process
GO:0046580involved_in negative regulation of Ras protein signal transduction1IDAHomo_sapiens(9606)Process
GO:0048593involved_in camera-type eye morphogenesis1IEAHomo_sapiens(9606)Process
GO:0048662involved_in negative regulation of smooth muscle cell proliferation1ISSHomo_sapiens(9606)Process
GO:0051646involved_in mitochondrion localization2IBA,IDAHomo_sapiens(9606)Process
GO:0061734involved_in parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization1ISSHomo_sapiens(9606)Process
GO:0120162involved_in positive regulation of cold-induced thermogenesis1ISSHomo_sapiens(9606)Process
GO:1904707involved_in positive regulation of vascular associated smooth muscle cell proliferation1IMPHomo_sapiens(9606)Process
GO:1905461involved_in positive regulation of vascular associated smooth muscle cell apoptotic process1IMPHomo_sapiens(9606)Process

Expression