Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases CancerSARS-COV-2
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000116288 Gene ID 11315 Accession 16369
Symbol PARK7 Alias DJ1;DJ-1;GATD2;HEL-S-67p Full Name Parkinsonism associated deglycase
Status Confidence Length 31215 bases Strand Plus strand
Position 1 : 7954291 - 7985505 RNA binding domain N.A.
Summary The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
22623418 Comparative label-free LC-MS/MS analysis of colorectal adenocarcinoma and metastatic cells treated with 5-fluorouracil. M Kerry Bauer 2012-06-01 Proteomics
33535093 New approaches to target RNA binding proteins. R Ashley Julio 2021-06-01 Current opinion in chemical biology
32357493 Novel Insights into PARK7 (DJ-1), a Potential Anti-Cancer Therapeutic Target, and Implications for Cancer Progression. Wook Jin 2020-04-26 Journal of clinical medicine

Transcripts

Name Transcript ID bp Protein Translation ID
PARK7-208 ENST00000493373 624 189aa ENSP00000465404
PARK7-205 ENST00000460192 567 No protein -
PARK7-209 ENST00000493678 1088 189aa ENSP00000418770
PARK7-204 ENST00000377493 795 169aa ENSP00000466242
PARK7-201 ENST00000338639 1127 189aa ENSP00000340278
PARK7-206 ENST00000465354 949 No protein -
PARK7-203 ENST00000377491 977 189aa ENSP00000366711
PARK7-202 ENST00000377488 783 189aa ENSP00000366708
PARK7-210 ENST00000497113 670 No protein -
PARK7-207 ENST00000469225 711 160aa ENSP00000466756

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
61127Colitis, Ulcerative6E-1426192919
67734Colitis, Ulcerative5E-921297633
72716Crohn Disease5E-926192919
77588Inflammatory Bowel Diseases1E-1228067908
83624Stroke2E-724262325
84003Colitis, Ulcerative4E-928067908
88542Inflammatory Bowel Diseases1E-1523128233
93890Celiac Disease9E-820190752
97594Crohn Disease3E-628067908

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000116288

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000116288homo_sapiensENSP00000340278100100nomascus_leucogenysENSNLEP00000043391100100
ENSG00000116288homo_sapiensENSP0000034027810099.4709pan_paniscusENSPPAP0000001452210099.4709
ENSG00000116288homo_sapiensENSP0000034027810098.9418pongo_abeliiENSPPYP000000431977574.2064
ENSG00000116288homo_sapiensENSP0000034027810099.4709pan_troglodytesENSPTRP0000007859810099.4709
ENSG00000116288homo_sapiensENSP0000034027882.010681.4815gorilla_gorillaENSGGOP0000001180510099.3548
ENSG00000116288homo_sapiensENSP0000034027891.534486.2434ornithorhynchus_anatinusENSOANP0000004815981.603876.8868
ENSG00000116288homo_sapiensENSP0000034027890.476283.5979sarcophilus_harrisiiENSSHAP0000002666691.443884.492
ENSG00000116288homo_sapiensENSP0000034027860.846658.2011notamacropus_eugeniiENSMEUP0000001347773.248470.0637
ENSG00000116288homo_sapiensENSP0000034027882.539780.9524choloepus_hoffmanniENSCHOP0000000385782.539780.9524
ENSG00000116288homo_sapiensENSP0000034027883.068879.3651dasypus_novemcinctusENSDNOP0000001914293.452489.2857
ENSG00000116288homo_sapiensENSP0000034027889.947185.1852dasypus_novemcinctusENSDNOP0000000028889.473784.7368
ENSG00000116288homo_sapiensENSP0000034027853.968351.8519erinaceus_europaeusENSEEUP0000001196396.226492.4528
ENSG00000116288homo_sapiensENSP0000034027871.428669.8413echinops_telfairiENSETEP0000000885585.44383.5443
ENSG00000116288homo_sapiensENSP0000034027878.83677.7778cercocebus_atysENSCATP0000002419299.333398
ENSG00000116288homo_sapiensENSP0000034027884.656184.6561cercocebus_atysENSCATP0000001607880.808180.8081
ENSG00000116288homo_sapiensENSP00000340278100100macaca_fascicularisENSMFAP00000029675100100
ENSG00000116288homo_sapiensENSP00000340278100100macaca_mulattaENSMMUP00000057842100100
ENSG00000116288homo_sapiensENSP0000034027877.777871.9577macaca_nemestrinaENSMNEP0000003413186.470680
ENSG00000116288homo_sapiensENSP00000340278100100macaca_nemestrinaENSMNEP00000011855100100
ENSG00000116288homo_sapiensENSP00000340278100100papio_anubisENSPANP00000030646100100
ENSG00000116288homo_sapiensENSP00000340278100100mandrillus_leucophaeusENSMLEP00000014543100100
ENSG00000116288homo_sapiensENSP0000034027895.767291.5344tursiops_truncatusENSTTRP0000001479095.767291.5344
ENSG00000116288homo_sapiensENSP0000034027898.412796.2963vulpes_vulpesENSVVUP0000003671098.412796.2963
ENSG00000116288homo_sapiensENSP0000034027895.767291.5344mus_spretusMGP_SPRETEiJ_P006853595.767291.5344
ENSG00000116288homo_sapiensENSP0000034027885.185280.4233equus_asinusENSEASP0000505395093.063687.8613
ENSG00000116288homo_sapiensENSP0000034027896.825495.2381capra_hircusENSCHIP0000002522796.825495.2381
ENSG00000116288homo_sapiensENSP0000034027897.883697.3545loxodonta_africanaENSLAFP0000001006297.883697.3545
ENSG00000116288homo_sapiensENSP0000034027898.412796.2963panthera_leoENSPLOP0000001545698.412796.2963
ENSG00000116288homo_sapiensENSP0000034027898.412796.2963ailuropoda_melanoleucaENSAMEP0000000391298.412796.2963
ENSG00000116288homo_sapiensENSP0000034027896.825496.2963bos_indicus_hybridENSBIXP0000503665196.825496.2963
ENSG00000116288homo_sapiensENSP0000034027885.185282.5397oryctolagus_cuniculusENSOCUP0000003919669.69767.5325
ENSG00000116288homo_sapiensENSP0000034027880.423375.1323equus_caballusENSECAP0000007146465.236160.9442
ENSG00000116288homo_sapiensENSP0000034027889.947184.6561canis_lupus_familiarisENSCAFP0084503791457.239153.8721
ENSG00000116288homo_sapiensENSP0000034027898.412796.2963panthera_pardusENSPPRP0000000126198.412796.2963
ENSG00000116288homo_sapiensENSP0000034027898.412794.1799marmota_marmota_marmotaENSMMMP0000001981998.412794.1799
ENSG00000116288homo_sapiensENSP0000034027896.825492.0635balaenoptera_musculusENSBMSP0001000780396.825492.0635
ENSG00000116288homo_sapiensENSP0000034027896.296392.5926cavia_porcellusENSCPOP0000000617696.296392.5926
ENSG00000116288homo_sapiensENSP0000034027898.412796.2963felis_catusENSFCAP0000001950798.412796.2963
ENSG00000116288homo_sapiensENSP0000034027898.412795.7672ursus_americanusENSUAMP0000001592698.412795.7672
ENSG00000116288homo_sapiensENSP0000034027889.947184.127monodelphis_domesticaENSMODP0000005785589.947184.127
ENSG00000116288homo_sapiensENSP0000034027896.825496.2963bison_bison_bisonENSBBBP0000002489896.825496.2963
ENSG00000116288homo_sapiensENSP0000034027895.767290.4762monodon_monocerosENSMMNP0001501220671.541567.5889
ENSG00000116288homo_sapiensENSP0000034027897.883696.2963sus_scrofaENSSSCP0000000367097.883696.2963
ENSG00000116288homo_sapiensENSP0000034027877.777874.0741microcebus_murinusENSMICP0000001698190.740786.4198
ENSG00000116288homo_sapiensENSP0000034027897.883694.1799microcebus_murinusENSMICP0000004096297.883694.1799
ENSG00000116288homo_sapiensENSP0000034027885.714380.4233microcebus_murinusENSMICP0000005020485.714380.4233
ENSG00000116288homo_sapiensENSP0000034027843.915343.3862octodon_degusENSODEP0000001812998.809597.619
ENSG00000116288homo_sapiensENSP0000034027843.915342.328jaculus_jaculusENSJJAP0000001232098.809595.2381
ENSG00000116288homo_sapiensENSP0000034027896.825495.7672ovis_aries_rambouilletENSOARP0002002542296.825495.7672
ENSG00000116288homo_sapiensENSP0000034027897.883695.2381ursus_maritimusENSUMAP0000003347197.883695.2381
ENSG00000116288homo_sapiensENSP0000034027870.899568.7831ochotona_princepsENSOPRP0000000197398.529495.5882
ENSG00000116288homo_sapiensENSP0000034027895.767290.4762delphinapterus_leucasENSDLEP0000001024995.767290.4762
ENSG00000116288homo_sapiensENSP0000034027896.825493.1217physeter_catodonENSPCTP0000500569496.825493.1217
ENSG00000116288homo_sapiensENSP0000034027888.359882.5397physeter_catodonENSPCTP0000502232294.886488.6364
ENSG00000116288homo_sapiensENSP0000034027895.767291.0053mus_caroliMGP_CAROLIEiJ_P006595995.767291.0053
ENSG00000116288homo_sapiensENSP0000034027895.767291.5344mus_musculusENSMUSP0000010129995.767291.5344
ENSG00000116288homo_sapiensENSP0000034027895.767286.7725dipodomys_ordiiENSDORP0000002280095.767286.7725
ENSG00000116288homo_sapiensENSP0000034027897.354594.1799mustela_putorius_furoENSMPUP0000000652897.354594.1799
ENSG00000116288homo_sapiensENSP0000034027866.137661.9048saimiri_boliviensis_boliviensisENSSBOP0000001768791.911886.0294
ENSG00000116288homo_sapiensENSP0000034027874.603273.0159vicugna_pacosENSVPAP0000001031497.916795.8333
ENSG00000116288homo_sapiensENSP0000034027810099.4709chlorocebus_sabaeusENSCSAP0000001725010099.4709
ENSG00000116288homo_sapiensENSP0000034027887.830787.3016tupaia_belangeriENSTBEP0000000820287.830787.3016
ENSG00000116288homo_sapiensENSP0000034027890.476284.6561mesocricetus_auratusENSMAUP0000001530190.957485.1064
ENSG00000116288homo_sapiensENSP0000034027896.296391.5344phocoena_sinusENSPSNP0000000997296.296391.5344
ENSG00000116288homo_sapiensENSP0000034027897.883695.2381camelus_dromedariusENSCDRP0000501505997.883695.2381
ENSG00000116288homo_sapiensENSP0000034027887.830782.5397carlito_syrichtaENSTSYP0000001530593.785388.1356
ENSG00000116288homo_sapiensENSP0000034027897.883696.2963carlito_syrichtaENSTSYP0000001566197.883696.2963
ENSG00000116288homo_sapiensENSP0000034027898.412796.2963panthera_tigris_altaicaENSPTIP0000002408298.412796.2963
ENSG00000116288homo_sapiensENSP0000034027862.96354.4974rattus_norvegicusENSRNOP0000007972666.853957.8652
ENSG00000116288homo_sapiensENSP0000034027898.412795.7672prolemur_simusENSPSMP0000003397898.412795.7672
ENSG00000116288homo_sapiensENSP0000034027896.825492.5926microtus_ochrogasterENSMOCP0000001888196.825492.5926
ENSG00000116288homo_sapiensENSP0000034027897.354592.5926peromyscus_maniculatus_bairdiiENSPEMP0000001832497.354592.5926
ENSG00000116288homo_sapiensENSP0000034027896.825496.2963bos_mutusENSBMUP0000000149496.825496.2963
ENSG00000116288homo_sapiensENSP0000034027895.238189.9471mus_spicilegusENSMSIP0000002915495.238189.9471
ENSG00000116288homo_sapiensENSP0000034027895.767291.5344mus_spicilegusENSMSIP0000001280095.767291.5344
ENSG00000116288homo_sapiensENSP0000034027897.883690.4762cricetulus_griseus_chok1gshdENSCGRP0000101997997.883690.4762
ENSG00000116288homo_sapiensENSP0000034027897.354593.1217pteropus_vampyrusENSPVAP0000001578297.354593.1217
ENSG00000116288homo_sapiensENSP0000034027897.883694.709myotis_lucifugusENSMLUP0000000179897.883694.709
ENSG00000116288homo_sapiensENSP0000034027892.063588.3598vombatus_ursinusENSVURP0001003165592.063588.3598
ENSG00000116288homo_sapiensENSP0000034027869.841364.5503rhinolophus_ferrumequinumENSRFEP0001000252089.189282.4324
ENSG00000116288homo_sapiensENSP0000034027889.947187.3016rhinolophus_ferrumequinumENSRFEP0001000179995.505692.6966
ENSG00000116288homo_sapiensENSP0000034027878.306975.6614rhinolophus_ferrumequinumENSRFEP0001001577996.73293.4641
ENSG00000116288homo_sapiensENSP0000034027897.883694.709rhinolophus_ferrumequinumENSRFEP0001001808097.883694.709
ENSG00000116288homo_sapiensENSP0000034027896.825494.1799neovison_visonENSNVIP0000000763796.825494.1799
ENSG00000116288homo_sapiensENSP0000034027896.825496.2963bos_taurusENSBTAP0000002733996.825496.2963
ENSG00000116288homo_sapiensENSP0000034027870.370461.3757heterocephalus_glaber_femaleENSHGLP0000003725351.75145.1362
ENSG00000116288homo_sapiensENSP0000034027888.888987.8307rhinopithecus_bietiENSRBIP0000002455287.958186.911
ENSG00000116288homo_sapiensENSP0000034027898.412795.7672canis_lupus_dingoENSCAFP0002000999598.412795.7672
ENSG00000116288homo_sapiensENSP0000034027898.412794.1799sciurus_vulgarisENSSVLP0000500504698.412794.1799
ENSG00000116288homo_sapiensENSP0000034027894.179988.3598phascolarctos_cinereusENSPCIP0000002358994.179988.3598
ENSG00000116288homo_sapiensENSP0000034027898.412796.8254procavia_capensisENSPCAP0000001212798.412796.8254
ENSG00000116288homo_sapiensENSP0000034027844.444443.9153nannospalax_galiliENSNGAP0000001159710098.8095
ENSG00000116288homo_sapiensENSP0000034027896.825496.2963bos_grunniensENSBGRP0000002098296.825496.2963
ENSG00000116288homo_sapiensENSP0000034027896.825493.6508chinchilla_lanigeraENSCLAP0000000909496.825493.6508
ENSG00000116288homo_sapiensENSP0000034027883.068878.836cervus_hanglu_yarkandensisENSCHYP0000002556169.777866.2222
ENSG00000116288homo_sapiensENSP0000034027898.412796.8254catagonus_wagneriENSCWAP0000000513898.412796.8254
ENSG00000116288homo_sapiensENSP0000034027898.412794.1799ictidomys_tridecemlineatusENSSTOP0000002241598.412794.1799
ENSG00000116288homo_sapiensENSP0000034027897.883695.7672otolemur_garnettiiENSOGAP0000000578797.883695.7672
ENSG00000116288homo_sapiensENSP0000034027880.423374.6032cebus_imitatorENSCCAP0000000973687.356381.0345
ENSG00000116288homo_sapiensENSP0000034027871.428667.7249cebus_imitatorENSCCAP0000001384888.235383.6601
ENSG00000116288homo_sapiensENSP0000034027898.412794.1799urocitellus_parryiiENSUPAP0001001470598.412794.1799
ENSG00000116288homo_sapiensENSP0000034027896.825495.7672moschus_moschiferusENSMMSP0000001281596.825495.7672
ENSG00000116288homo_sapiensENSP0000034027899.470999.4709rhinopithecus_roxellanaENSRROP0000004220699.470999.4709
ENSG00000116288homo_sapiensENSP0000034027895.767291.5344mus_pahariMGP_PahariEiJ_P008106495.767291.5344
ENSG00000116288homo_sapiensENSP0000034027877.777871.9577propithecus_coquereliENSPCOP000000156428477.7143
ENSG00000116288homo_sapiensENSP0000034027897.883694.709propithecus_coquereliENSPCOP0000000455897.883694.709
ENSG00000116288homo_sapiensENSP0000034027880.423378.3069propithecus_coquereliENSPCOP0000002939498.064595.4839
ENSG00000116288homo_sapiensENSP0000034027860.317543.3862caenorhabditis_elegansC49G7.11.161.290344.086
ENSG00000116288homo_sapiensENSP0000034027867.195852.381caenorhabditis_elegansB0432.2.167.914452.9412
ENSG00000116288homo_sapiensENSP0000034027867.724953.4392drosophila_melanogasterFBpp008674158.986246.5438
ENSG00000116288homo_sapiensENSP0000034027868.25451.8519drosophila_melanogasterFBpp040145668.98452.4064
ENSG00000116288homo_sapiensENSP0000034027864.550344.9735ciona_intestinalisENSCINP0000000746565.240645.4545
ENSG00000116288homo_sapiensENSP0000034027888.359881.4815petromyzon_marinusENSPMAP0000000123088.359881.4815
ENSG00000116288homo_sapiensENSP0000034027861.375751.3228eptatretus_burgeriENSEBUP0000000639662.702752.4324
ENSG00000116288homo_sapiensENSP0000034027889.41879.3651callorhinchus_miliiENSCMIP0000001588389.893679.7872
ENSG00000116288homo_sapiensENSP0000034027891.534480.9524latimeria_chalumnaeENSLACP0000000948379.723570.5069
ENSG00000116288homo_sapiensENSP0000034027892.592683.0688lepisosteus_oculatusENSLOCP0000000459392.592683.0688
ENSG00000116288homo_sapiensENSP0000034027887.830779.8942clupea_harengusENSCHAP0000001982687.830779.8942
ENSG00000116288homo_sapiensENSP0000034027889.947183.0688danio_rerioENSDARP0000015043589.947183.0688
ENSG00000116288homo_sapiensENSP0000034027889.41882.5397carassius_auratusENSCARP0000001396989.41882.5397
ENSG00000116288homo_sapiensENSP0000034027889.947183.0688carassius_auratusENSCARP0000006349889.947183.0688
ENSG00000116288homo_sapiensENSP0000034027889.947182.5397astyanax_mexicanusENSAMXP0000000390889.947182.5397
ENSG00000116288homo_sapiensENSP0000034027890.476284.6561ictalurus_punctatusENSIPUP0000000479490.476284.6561
ENSG00000116288homo_sapiensENSP0000034027889.41882.0106esox_luciusENSELUP0000003331189.41882.0106
ENSG00000116288homo_sapiensENSP0000034027890.476280.4233electrophorus_electricusENSEEEP0000002844282.211573.0769
ENSG00000116288homo_sapiensENSP0000034027889.947181.4815oncorhynchus_kisutchENSOKIP0000510990689.947181.4815
ENSG00000116288homo_sapiensENSP0000034027888.888980.9524oncorhynchus_kisutchENSOKIP0000509318388.888980.9524
ENSG00000116288homo_sapiensENSP0000034027889.947181.4815oncorhynchus_mykissENSOMYP0000006161389.947181.4815
ENSG00000116288homo_sapiensENSP0000034027888.888980.9524oncorhynchus_mykissENSOMYP0000002675188.888980.9524
ENSG00000116288homo_sapiensENSP0000034027889.41880.9524salmo_salarENSSSAP0000009269284.924676.8844
ENSG00000116288homo_sapiensENSP0000034027888.888980.9524salmo_truttaENSSTUP0000000960788.888980.9524
ENSG00000116288homo_sapiensENSP0000034027889.41880.9524salmo_truttaENSSTUP0000002059389.41880.9524
ENSG00000116288homo_sapiensENSP0000034027887.830778.836gadus_morhuaENSGMOP0000000160287.830778.836
ENSG00000116288homo_sapiensENSP0000034027862.96353.4392fundulus_heteroclitusENSFHEP0000002076676.774265.1613
ENSG00000116288homo_sapiensENSP0000034027887.830779.3651poecilia_reticulataENSPREP0000000859787.830779.3651
ENSG00000116288homo_sapiensENSP0000034027887.830778.836xiphophorus_maculatusENSXMAP0000003157087.830778.836
ENSG00000116288homo_sapiensENSP0000034027887.301679.3651oryzias_latipesENSORLP0000000536487.301679.3651
ENSG00000116288homo_sapiensENSP0000034027886.772578.836cyclopterus_lumpusENSCLMP0000500347386.772578.836
ENSG00000116288homo_sapiensENSP0000034027888.359879.8942oreochromis_niloticusENSONIP0000005609285.204177.0408
ENSG00000116288homo_sapiensENSP0000034027888.888978.836haplochromis_burtoniENSHBUP0000003050788.888978.836
ENSG00000116288homo_sapiensENSP0000034027888.359878.836astatotilapia_callipteraENSACLP0000002390188.359878.836
ENSG00000116288homo_sapiensENSP0000034027888.359877.7778sparus_aurataENSSAUP0001003192088.359877.7778
ENSG00000116288homo_sapiensENSP0000034027888.359879.8942lates_calcariferENSLCAP0001005238288.359879.8942
ENSG00000116288homo_sapiensENSP0000034027885.714377.2487xenopus_tropicalisENSXETP0000001325185.714377.2487
ENSG00000116288homo_sapiensENSP0000034027891.534487.8307chrysemys_picta_belliiENSCPBP0000002243991.534487.8307
ENSG00000116288homo_sapiensENSP0000034027893.121791.5344sphenodon_punctatusENSSPUP0000001563293.121791.5344
ENSG00000116288homo_sapiensENSP0000034027893.121786.2434crocodylus_porosusENSCPRP0000501594493.121786.2434
ENSG00000116288homo_sapiensENSP0000034027892.063586.2434laticauda_laticaudataENSLLTP0000000889058.585954.8822
ENSG00000116288homo_sapiensENSP0000034027892.063585.7143notechis_scutatusENSNSUP0000000250592.063585.7143
ENSG00000116288homo_sapiensENSP0000034027891.005384.6561pseudonaja_textilisENSPTXP0000002370191.005384.6561
ENSG00000116288homo_sapiensENSP0000034027889.41885.1852anas_platyrhynchos_platyrhynchosENSAPLP0000001054092.349787.9781
ENSG00000116288homo_sapiensENSP0000034027895.238190.4762gallus_gallusENSGALP0001002702786.956582.6087
ENSG00000116288homo_sapiensENSP0000034027884.656180.4233meleagris_gallopavoENSMGAP0000000029894.674689.9408
ENSG00000116288homo_sapiensENSP0000034027894.70989.9471serinus_canariaENSSCAP0000000337994.70989.9471
ENSG00000116288homo_sapiensENSP0000034027892.063586.7725parus_majorENSPMJP0000001373789.230884.1026
ENSG00000116288homo_sapiensENSP0000034027891.534486.2434anolis_carolinensisENSACAP0000001713091.534486.2434
ENSG00000116288homo_sapiensENSP0000034027888.888979.3651neolamprologus_brichardiENSNBRP0000002748388.888979.3651
ENSG00000116288homo_sapiensENSP0000034027892.592686.2434naja_najaENSNNAP0000001890062.72458.4229
ENSG00000116288homo_sapiensENSP0000034027891.534485.7143podarcis_muralisENSPMRP0000001921991.534485.7143
ENSG00000116288homo_sapiensENSP0000034027894.70989.9471geospiza_fortisENSGFOP0000001487587.317182.9268
ENSG00000116288homo_sapiensENSP0000034027892.063586.7725taeniopygia_guttataENSTGUP0000000260674.678170.3863
ENSG00000116288homo_sapiensENSP0000034027893.121785.7143erpetoichthys_calabaricusENSECRP0000000989893.121785.7143
ENSG00000116288homo_sapiensENSP0000034027887.830777.7778kryptolebias_marmoratusENSKMAP0000001309487.830777.7778
ENSG00000116288homo_sapiensENSP0000034027867.195858.2011salvator_merianaeENSSMRP0000002267856.444448.8889
ENSG00000116288homo_sapiensENSP0000034027887.830780.4233oryzias_javanicusENSOJAP0000003517387.830780.4233
ENSG00000116288homo_sapiensENSP0000034027888.359879.8942amphilophus_citrinellusENSACIP0000001026788.359879.8942
ENSG00000116288homo_sapiensENSP0000034027879.365169.8413amphiprion_perculaENSAPEP0000000643986.705276.3006
ENSG00000116288homo_sapiensENSP0000034027887.301679.3651oryzias_sinensisENSOSIP0000001140987.301679.3651
ENSG00000116288homo_sapiensENSP0000034027891.534486.7725pelodiscus_sinensisENSPSIP0000001521991.534486.7725
ENSG00000116288homo_sapiensENSP0000034027891.534488.3598gopherus_evgoodeiENSGEVP0000502876491.534488.3598
ENSG00000116288homo_sapiensENSP0000034027883.597978.3069chelonoidis_abingdoniiENSCABP0000002395971.171266.6667
ENSG00000116288homo_sapiensENSP0000034027888.359880.4233seriola_dumeriliENSSDUP0000002092188.359880.4233
ENSG00000116288homo_sapiensENSP0000034027883.068873.545cottoperca_gobioENSCGOP0000000021287.709577.6536
ENSG00000116288homo_sapiensENSP0000034027893.121788.3598struthio_camelus_australisENSSCUP0000000706264.233660.9489
ENSG00000116288homo_sapiensENSP0000034027894.179988.8889anser_brachyrhynchusENSABRP0000001698394.179988.8889
ENSG00000116288homo_sapiensENSP0000034027888.359879.8942gasterosteus_aculeatusENSGACP0000000221888.359879.8942
ENSG00000116288homo_sapiensENSP0000034027886.243476.1905cynoglossus_semilaevisENSCSEP0000003376073.755765.1584
ENSG00000116288homo_sapiensENSP0000034027887.301679.3651poecilia_formosaENSPFOP0000001395587.301679.3651
ENSG00000116288homo_sapiensENSP0000034027888.359882.0106myripristis_murdjanENSMMDP0000505063488.359882.0106
ENSG00000116288homo_sapiensENSP0000034027887.830778.836sander_luciopercaENSSLUP0000001788287.830778.836
ENSG00000116288homo_sapiensENSP0000034027893.650889.9471strigops_habroptilaENSSHBP0000502215793.650889.9471
ENSG00000116288homo_sapiensENSP0000034027887.301677.2487amphiprion_ocellarisENSAOCP0000000342287.301677.2487
ENSG00000116288homo_sapiensENSP0000034027891.534487.8307terrapene_carolina_triunguisENSTMTP0000000966891.534487.8307
ENSG00000116288homo_sapiensENSP0000034027889.41880.9524hucho_huchoENSHHUP0000005159889.41880.9524
ENSG00000116288homo_sapiensENSP0000034027888.888982.0106hucho_huchoENSHHUP0000008914188.888982.0106
ENSG00000116288homo_sapiensENSP0000034027878.306966.1376betta_splendensENSBSLP0000004869466.666756.3063
ENSG00000116288homo_sapiensENSP0000034027891.005383.5979pygocentrus_nattereriENSPNAP0000003649691.005383.5979
ENSG00000116288homo_sapiensENSP0000034027886.772576.7196anabas_testudineusENSATEP0000003633486.772576.7196
ENSG00000116288homo_sapiensENSP0000034027866.137650.2645ciona_savignyiENSCSAVP0000000617767.934851.6304
ENSG00000116288homo_sapiensENSP0000034027888.359880.4233seriola_lalandi_dorsalisENSSLDP0000000582588.359880.4233
ENSG00000116288homo_sapiensENSP0000034027888.359880.4233labrus_bergyltaENSLBEP0000003288667.068361.0442
ENSG00000116288homo_sapiensENSP0000034027888.359878.836pundamilia_nyerereiENSPNYP0000002448288.359878.836
ENSG00000116288homo_sapiensENSP0000034027888.888979.8942mastacembelus_armatusENSMAMP0000002247088.888979.8942
ENSG00000116288homo_sapiensENSP0000034027887.830779.8942stegastes_partitusENSSPAP0000000996887.830779.8942
ENSG00000116288homo_sapiensENSP0000034027888.888980.9524oncorhynchus_tshawytschaENSOTSP0000504248288.888980.9524
ENSG00000116288homo_sapiensENSP0000034027889.947181.4815oncorhynchus_tshawytschaENSOTSP0000505933389.947181.4815
ENSG00000116288homo_sapiensENSP0000034027886.772576.7196acanthochromis_polyacanthusENSAPOP0000000981886.772576.7196
ENSG00000116288homo_sapiensENSP0000034027891.005387.3016aquila_chrysaetos_chrysaetosENSACCP0002000282769.918767.0732
ENSG00000116288homo_sapiensENSP0000034027887.301675.6614nothobranchius_furzeriENSNFUP0001504393587.301675.6614
ENSG00000116288homo_sapiensENSP0000034027888.359881.4815cyprinodon_variegatusENSCVAP0000000997688.359881.4815
ENSG00000116288homo_sapiensENSP0000034027891.005383.0688denticeps_clupeoidesENSDCDP0000005422891.005383.0688
ENSG00000116288homo_sapiensENSP0000034027887.830779.3651larimichthys_croceaENSLCRP0000505838887.830779.3651
ENSG00000116288homo_sapiensENSP0000034027888.888980.9524takifugu_rubripesENSTRUP0000005586988.888980.9524
ENSG00000116288homo_sapiensENSP0000034027891.534485.7143ficedula_albicollisENSFALP0000001032990.575984.8168
ENSG00000116288homo_sapiensENSP0000034027887.301677.2487hippocampus_comesENSHCOP0000001641970.512862.3932
ENSG00000116288homo_sapiensENSP0000034027880.423374.0741cyprinus_carpio_carpioENSCCRP0000005672289.940882.8402
ENSG00000116288homo_sapiensENSP0000034027889.41882.5397cyprinus_carpio_carpioENSCCRP0000000677482.038875.7282
ENSG00000116288homo_sapiensENSP0000034027894.70990.4762coturnix_japonicaENSCJPP0000500821194.70990.4762
ENSG00000116288homo_sapiensENSP0000034027887.301678.836poecilia_latipinnaENSPLAP0000002827387.301678.836
ENSG00000116288homo_sapiensENSP0000034027887.301678.836poecilia_latipinnaENSPLAP0000002502387.301678.836
ENSG00000116288homo_sapiensENSP0000034027888.359878.836maylandia_zebraENSMZEP0000501870188.359878.836
ENSG00000116288homo_sapiensENSP0000034027888.359879.3651tetraodon_nigroviridisENSTNIP0000001783788.359879.3651
ENSG00000116288homo_sapiensENSP0000034027892.063586.2434paramormyrops_kingsleyaeENSPKIP0000003463092.063586.2434
ENSG00000116288homo_sapiensENSP0000034027888.359878.3069scleropages_formosusENSSFOP0001501114188.359878.3069
ENSG00000116288homo_sapiensENSP0000034027886.772577.7778scophthalmus_maximusENSSMAP0000002405087.23478.1915
ENSG00000116288homo_sapiensENSP0000034027887.301679.3651oryzias_melastigmaENSOMEP0000001958087.301679.3651

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000785part_of chromatin1IDAHomo_sapiens(9606)Component
GO:0001046NOT enables core promoter sequence-specific DNA binding1ICHomo_sapiens(9606)Function
GO:0001933involved_in negative regulation of protein phosphorylation1IGIHomo_sapiens(9606)Process
GO:0002866involved_in positive regulation of acute inflammatory response to antigenic stimulus1ISSHomo_sapiens(9606)Process
GO:0003690NOT enables double-stranded DNA binding1IDAHomo_sapiens(9606)Function
GO:0003697NOT enables single-stranded DNA binding1IDAHomo_sapiens(9606)Function
GO:0003713enables transcription coactivator activity2IGI,TASHomo_sapiens(9606)Function
GO:0003729enables mRNA binding1IDAHomo_sapiens(9606)Function
GO:0005102enables signaling receptor binding1IPIHomo_sapiens(9606)Function
GO:0005507enables copper ion binding1IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus3HDA,IBA,IDAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm2IBA,IDAHomo_sapiens(9606)Component
GO:0005739is_active_in mitochondrion3IBA,IDA,IMPHomo_sapiens(9606)Component
GO:0005758located_in mitochondrial intermembrane space1IEAHomo_sapiens(9606)Component
GO:0005759located_in mitochondrial matrix1IEAHomo_sapiens(9606)Component
GO:0005783located_in endoplasmic reticulum1IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol3IDA,IMP,TASHomo_sapiens(9606)Component
GO:0005886located_in plasma membrane1IEAHomo_sapiens(9606)Component
GO:0005912located_in adherens junction1HDAHomo_sapiens(9606)Component
GO:0006281involved_in DNA repair1IDAHomo_sapiens(9606)Process
GO:0006469involved_in negative regulation of protein kinase activity1IGIHomo_sapiens(9606)Process
GO:0006508involved_in proteolysis1IEAHomo_sapiens(9606)Process
GO:0006517NOT involved_in protein deglycosylation3IDA,IMPHomo_sapiens(9606)Process
GO:0006914involved_in autophagy1IEAHomo_sapiens(9606)Process
GO:0006954involved_in inflammatory response1IEAHomo_sapiens(9606)Process
GO:0006979involved_in response to oxidative stress1IBAHomo_sapiens(9606)Process
GO:0007005involved_in mitochondrion organization1ISSHomo_sapiens(9606)Process
GO:0007265involved_in Ras protein signal transduction1TASHomo_sapiens(9606)Process
GO:0007338involved_in single fertilization1IEAHomo_sapiens(9606)Process
GO:0008233enables peptidase activity1IDAHomo_sapiens(9606)Function
GO:0008344involved_in adult locomotory behavior1IEAHomo_sapiens(9606)Process
GO:0009438NOT involved_in methylglyoxal metabolic process2IDAHomo_sapiens(9606)Process
GO:0010273involved_in detoxification of copper ion1IMPHomo_sapiens(9606)Process
GO:0010628involved_in positive regulation of gene expression1TASHomo_sapiens(9606)Process
GO:0010629involved_in negative regulation of gene expression1IDAHomo_sapiens(9606)Process
GO:0016532enables superoxide dismutase copper chaperone activity1IDAHomo_sapiens(9606)Function
GO:0016605located_in PML body1IDAHomo_sapiens(9606)Component
GO:0016684enables oxidoreductase activity, acting on peroxide as acceptor2IBA,IDAHomo_sapiens(9606)Function
GO:0019249involved_in lactate biosynthetic process1IDAHomo_sapiens(9606)Process
GO:0019826enables oxygen sensor activity1IEAHomo_sapiens(9606)Function
GO:0019899enables enzyme binding1IPIHomo_sapiens(9606)Function
GO:0019900enables kinase binding1IPIHomo_sapiens(9606)Function
GO:0019955enables cytokine binding1IPIHomo_sapiens(9606)Function
GO:0030073involved_in insulin secretion1ISSHomo_sapiens(9606)Process
GO:0030424located_in axon1ISSHomo_sapiens(9606)Component
GO:0031334involved_in positive regulation of protein-containing complex assembly1IDAHomo_sapiens(9606)Process
GO:0031397involved_in negative regulation of protein ubiquitination1IDAHomo_sapiens(9606)Process
GO:0032091involved_in negative regulation of protein binding3IDA,IGI,IMPHomo_sapiens(9606)Process
GO:0032148involved_in activation of protein kinase B activity1ICHomo_sapiens(9606)Process
GO:0032435involved_in negative regulation of proteasomal ubiquitin-dependent protein catabolic process1IDAHomo_sapiens(9606)Process
GO:0032679NOT involved_in regulation of TRAIL production1IMPHomo_sapiens(9606)Process
GO:0032757involved_in positive regulation of interleukin-8 production1IDAHomo_sapiens(9606)Process
GO:0033138involved_in positive regulation of peptidyl-serine phosphorylation1IMPHomo_sapiens(9606)Process
GO:0033234involved_in negative regulation of protein sumoylation1IDAHomo_sapiens(9606)Process
GO:0033864involved_in positive regulation of NAD(P)H oxidase activity1ISSHomo_sapiens(9606)Process
GO:0034599involved_in cellular response to oxidative stress2IDA,IMPHomo_sapiens(9606)Process
GO:0036470enables tyrosine 3-monooxygenase activator activity1IDAHomo_sapiens(9606)Function
GO:0036471involved_in cellular response to glyoxal1IDAHomo_sapiens(9606)Process
GO:0036478enables L-dopa decarboxylase activator activity1IDAHomo_sapiens(9606)Function
GO:0036524NOT enables protein deglycase activity2IDAHomo_sapiens(9606)Function
GO:0036526involved_in peptidyl-cysteine deglycation1IDAHomo_sapiens(9606)Process
GO:0036527involved_in peptidyl-arginine deglycation2IDA,IMPHomo_sapiens(9606)Process
GO:0036528involved_in peptidyl-lysine deglycation1IDAHomo_sapiens(9606)Process
GO:0036529involved_in protein deglycation, glyoxal removal1IDAHomo_sapiens(9606)Process
GO:0036530NOT involved_in protein deglycation, methylglyoxal removal3IDA,IMPHomo_sapiens(9606)Process
GO:0036531involved_in glutathione deglycation1IDAHomo_sapiens(9606)Process
GO:0042593involved_in glucose homeostasis1ISSHomo_sapiens(9606)Process
GO:0042743involved_in hydrogen peroxide metabolic process1IDAHomo_sapiens(9606)Process
GO:0042802enables identical protein binding1IPIHomo_sapiens(9606)Function
GO:0042803enables protein homodimerization activity2IDA,IPIHomo_sapiens(9606)Function
GO:0043523involved_in regulation of neuron apoptotic process1IDAHomo_sapiens(9606)Process
GO:0043524involved_in negative regulation of neuron apoptotic process1IDAHomo_sapiens(9606)Process
GO:0044297located_in cell body1IEAHomo_sapiens(9606)Component
GO:0044388enables small protein activating enzyme binding1IPIHomo_sapiens(9606)Function
GO:0044390enables ubiquitin-like protein conjugating enzyme binding1IPIHomo_sapiens(9606)Function
GO:0044877enables protein-containing complex binding1IDAHomo_sapiens(9606)Function
GO:0045121located_in membrane raft1IEAHomo_sapiens(9606)Component
GO:0045296enables cadherin binding1HDAHomo_sapiens(9606)Function
GO:0045340enables mercury ion binding1IDAHomo_sapiens(9606)Function
GO:0045944involved_in positive regulation of transcription by RNA polymerase II3IDA,IGI,IMPHomo_sapiens(9606)Process
GO:0046295involved_in glycolate biosynthetic process2IBA,IDAHomo_sapiens(9606)Process
GO:0046826involved_in negative regulation of protein export from nucleus1IGIHomo_sapiens(9606)Process
GO:0048471located_in perinuclear region of cytoplasm1IDAHomo_sapiens(9606)Component
GO:0050681enables nuclear androgen receptor binding1IPIHomo_sapiens(9606)Function
GO:0050727involved_in regulation of inflammatory response1ISSHomo_sapiens(9606)Process
GO:0050787involved_in detoxification of mercury ion1IMPHomo_sapiens(9606)Process
GO:0050821involved_in protein stabilization2IDA,IMPHomo_sapiens(9606)Process
GO:0051091involved_in positive regulation of DNA-binding transcription factor activity2IMP,TASHomo_sapiens(9606)Process
GO:0051444involved_in negative regulation of ubiquitin-protein transferase activity1IDAHomo_sapiens(9606)Process
GO:0051583involved_in dopamine uptake involved in synaptic transmission1IEAHomo_sapiens(9606)Process
GO:0051881involved_in regulation of mitochondrial membrane potential1IMPHomo_sapiens(9606)Process
GO:0051897involved_in positive regulation of protein kinase B signaling1ICHomo_sapiens(9606)Process
GO:0051899involved_in membrane depolarization1IEAHomo_sapiens(9606)Process
GO:0051920enables peroxiredoxin activity1IEAHomo_sapiens(9606)Function
GO:0060081involved_in membrane hyperpolarization1IEAHomo_sapiens(9606)Process
GO:0060765involved_in regulation of androgen receptor signaling pathway1IDAHomo_sapiens(9606)Process
GO:0061691involved_in detoxification of hydrogen peroxide1IDAHomo_sapiens(9606)Process
GO:0061727involved_in methylglyoxal catabolic process to lactate1IDAHomo_sapiens(9606)Process
GO:0070062located_in extracellular exosome1HDAHomo_sapiens(9606)Component
GO:0070301involved_in cellular response to hydrogen peroxide1IMPHomo_sapiens(9606)Process
GO:0070994involved_in detection of oxidative stress1IEAHomo_sapiens(9606)Process
GO:0097110enables scaffold protein binding1IPIHomo_sapiens(9606)Function
GO:0098793located_in presynapse1IEAHomo_sapiens(9606)Component
GO:0098869involved_in cellular oxidant detoxification1IEAHomo_sapiens(9606)Process
GO:0106044involved_in guanine deglycation1IDAHomo_sapiens(9606)Process
GO:0106045involved_in guanine deglycation, methylglyoxal removal1IDAHomo_sapiens(9606)Process
GO:0106046involved_in guanine deglycation, glyoxal removal1IDAHomo_sapiens(9606)Process
GO:0110095involved_in cellular detoxification of aldehyde1IDAHomo_sapiens(9606)Process
GO:0140041involved_in cellular detoxification of methylglyoxal1IDAHomo_sapiens(9606)Process
GO:0140297enables DNA-binding transcription factor binding1IPIHomo_sapiens(9606)Function
GO:1900182involved_in positive regulation of protein localization to nucleus2IDA,IMPHomo_sapiens(9606)Process
GO:1901215involved_in negative regulation of neuron death2IBA,IDAHomo_sapiens(9606)Process
GO:1901671involved_in positive regulation of superoxide dismutase activity1IDAHomo_sapiens(9606)Process
GO:1901984involved_in negative regulation of protein acetylation1IDAHomo_sapiens(9606)Process
GO:1902176acts_upstream_of negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway1IDAHomo_sapiens(9606)Process
GO:1902177involved_in positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway1IEAHomo_sapiens(9606)Process
GO:1902236involved_in negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway1IGIHomo_sapiens(9606)Process
GO:1902903involved_in regulation of supramolecular fiber organization1TASHomo_sapiens(9606)Process
GO:1902958involved_in positive regulation of mitochondrial electron transport, NADH to ubiquinone1IMPHomo_sapiens(9606)Process
GO:1903073involved_in negative regulation of death-inducing signaling complex assembly1ICHomo_sapiens(9606)Process
GO:1903094involved_in negative regulation of protein K48-linked deubiquitination1IDAHomo_sapiens(9606)Process
GO:1903122involved_in negative regulation of TRAIL-activated apoptotic signaling pathway1IMPHomo_sapiens(9606)Process
GO:1903135enables cupric ion binding1IDAHomo_sapiens(9606)Function
GO:1903136enables cuprous ion binding1IDAHomo_sapiens(9606)Function
GO:1903168involved_in positive regulation of pyrroline-5-carboxylate reductase activity1IDAHomo_sapiens(9606)Process
GO:1903178involved_in positive regulation of tyrosine 3-monooxygenase activity1IDAHomo_sapiens(9606)Process
GO:1903181involved_in positive regulation of dopamine biosynthetic process2IC,IDAHomo_sapiens(9606)Process
GO:1903189involved_in glyoxal metabolic process2IBA,IDAHomo_sapiens(9606)Process
GO:1903190involved_in glyoxal catabolic process1IEAHomo_sapiens(9606)Process
GO:1903197involved_in positive regulation of L-dopa biosynthetic process1IMPHomo_sapiens(9606)Process
GO:1903200involved_in positive regulation of L-dopa decarboxylase activity1IDAHomo_sapiens(9606)Process
GO:1903376involved_in regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway1IDAHomo_sapiens(9606)Process
GO:1903377involved_in negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway2IDA,IMPHomo_sapiens(9606)Process
GO:1903384involved_in negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway1IGIHomo_sapiens(9606)Process
GO:1903427involved_in negative regulation of reactive oxygen species biosynthetic process1ISSHomo_sapiens(9606)Process
GO:1903428involved_in positive regulation of reactive oxygen species biosynthetic process1IEAHomo_sapiens(9606)Process
GO:1903599involved_in positive regulation of autophagy of mitochondrion1NASHomo_sapiens(9606)Process
GO:1903751involved_in negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide1IDAHomo_sapiens(9606)Process
GO:1905259involved_in negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway1IDAHomo_sapiens(9606)Process
GO:1990381enables ubiquitin-specific protease binding1IPIHomo_sapiens(9606)Function
GO:1990422enables glyoxalase (glycolic acid-forming) activity1IDAHomo_sapiens(9606)Function
GO:2000157involved_in negative regulation of ubiquitin-specific protease activity1IDAHomo_sapiens(9606)Process
GO:2000277involved_in positive regulation of oxidative phosphorylation uncoupler activity1IEAHomo_sapiens(9606)Process
GO:2000379involved_in positive regulation of reactive oxygen species metabolic process1IDAHomo_sapiens(9606)Process
GO:2000679involved_in positive regulation of transcription regulatory region DNA binding1IMPHomo_sapiens(9606)Process
GO:2000825involved_in positive regulation of androgen receptor activity1IMPHomo_sapiens(9606)Process
GO:2001237involved_in negative regulation of extrinsic apoptotic signaling pathway1IMPHomo_sapiens(9606)Process
GO:2001268involved_in negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway1IMPHomo_sapiens(9606)Process

Expression