RBPWorld - a comprehensive database of RNA Binding Proteins

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Functions and Diseases

RBP Type	Non-canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	E3 ligase
Localizations	Nucleoli
BulkPerturb-seq

Description

Ensembl ID	ENSG00000114626	Gene ID	80325	Accession	18275
Symbol	ABTB1	Alias	BPOZ;BTB3;BPOZ-2;BTBD21;EF1ABP;PP2259	Full Name	ankyrin repeat and BTB domain containing 1
Status	Confidence	Length	7992 bases	Strand	Plus strand
Position	3 : 127672935 - 127680926	RNA binding domain	N.A.
Summary	This gene encodes a protein with an ankyrin repeat region and two BTB/POZ domains, which are thought to be involved in protein-protein interactions. Expression of this gene is activated by the phosphatase and tensin homolog, a tumor suppressor. Alternate splicing results in three transcript variants. [provided by RefSeq, Mar 2010]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
ABTB1-212	ENST00000483857	1027	57aa	ENSP00000420748
ABTB1-209	ENST00000475265	1108	No protein	-
ABTB1-214	ENST00000493365	715	No protein	-
ABTB1-201	ENST00000232744	1962	478aa	ENSP00000232744
ABTB1-202	ENST00000453791	1961	336aa	ENSP00000412684
ABTB1-208	ENST00000475042	1915	57aa	ENSP00000418641
ABTB1-204	ENST00000466612	715	No protein	-
ABTB1-211	ENST00000479280	746	No protein	-
ABTB1-205	ENST00000467179	691	No protein	-
ABTB1-206	ENST00000468137	2065	336aa	ENSP00000417366
ABTB1-203	ENST00000464431	5061	No protein	-
ABTB1-213	ENST00000491633	471	No protein	-
ABTB1-210	ENST00000478298	818	No protein	-
ABTB1-207	ENST00000474129	683	No protein	-
ABTB1-215	ENST00000497162	563	141aa	ENSP00000418439

Gene Model

Click here to download ENSG00000114626's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID
55117	Lactate Dehydrogenases	5.4520000E-005	-

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000114626's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000151	part_of ubiquitin ligase complex	1	IBA	Homo_sapiens(9606)	Component
GO:0003746	enables translation elongation factor activity	1	IEA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005730	located_in nucleolus	1	IDA	Homo_sapiens(9606)	Component
GO:0005737	is_active_in cytoplasm	1	IBA	Homo_sapiens(9606)	Component
GO:0005829	located_in cytosol	1	IDA	Homo_sapiens(9606)	Component
GO:0005886	located_in plasma membrane	1	IDA	Homo_sapiens(9606)	Component
GO:0006414	involved_in translational elongation	1	IEA	Homo_sapiens(9606)	Process

Expression