Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000113522 Gene ID 10111 Accession 9816
Symbol RAD50 Alias NBSLD;RAD502;hRad50 Full Name RAD50 double strand break repair protein
Status Confidence Length 90331 bases Strand Plus strand
Position 5 : 132556019 - 132646349 RNA binding domain N.A.
Summary The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.[provided by RefSeq, Apr 2010]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
36762186 Proteomics approach to investigating osmotic stress effects on pistachio. Rambod Pakzad 2022-01-01 Frontiers in plant science
35453338 Metabolic Stress and Mitochondrial Dysfunction in Ataxia-Telangiectasia. Narayanan Goutham Subramanian 2022-03-28 Antioxidants (Basel, Switzerland)
29317520 ATM directs DNA damage responses and proteostasis via genetically separable pathways. Ji-Hoon Lee 2018-01-09 Science signaling

Transcripts

Name Transcript ID bp Protein Translation ID
RAD50-202 ENST00000416135 923 100aa ENSP00000389515
RAD50-212 ENST00000651541 1695 482aa ENSP00000498795
RAD50-209 ENST00000533482 4373 102aa ENSP00000431225
RAD50-201 ENST00000378823 8272 1312aa ENSP00000368100
RAD50-215 ENST00000652016 3134 606aa ENSP00000498267
RAD50-216 ENST00000652485 3027 894aa ENSP00000498973
RAD50-210 ENST00000651160 3449 659aa ENSP00000498829
RAD50-214 ENST00000651723 3471 47aa ENSP00000498237
RAD50-205 ENST00000453394 2076 660aa ENSP00000400049
RAD50-203 ENST00000423956 2915 551aa ENSP00000390971
RAD50-213 ENST00000651658 3055 No protein -
RAD50-207 ENST00000487596 738 No protein -
RAD50-204 ENST00000434288 1052 158aa ENSP00000396100
RAD50-208 ENST00000496204 473 No protein -
RAD50-211 ENST00000651249 3870 258aa ENSP00000498257
RAD50-206 ENST00000455677 564 157aa ENSP00000396860

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
86235Asthma2E-1627182965
92393Venous Thromboembolism9E-628203683
92547Dermatitis, Atopic4E-725865352
94011Asthma3E-720159242
95023Dermatitis, Atopic2E-1825574825
95024Psoriasis2E-1825574825
96831Asthma2E-727611488
96866Immunoglobulin E4E-818846228
100308Dermatitis, Atopic4E-1726482879
101840Asthma8E-724241537

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000113522

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000113522homo_sapiensENSP0000036810099.618999.314nomascus_leucogenysENSNLEP0000001551299.54399.2384
ENSG00000113522homo_sapiensENSP0000036810010099.8476pan_paniscusENSPPAP0000001333210099.8476
ENSG00000113522homo_sapiensENSP0000036810010099.7713pongo_abeliiENSPPYP0000001763010099.7713
ENSG00000113522homo_sapiensENSP0000036810010099.8476pan_troglodytesENSPTRP0000002946210099.8476
ENSG00000113522homo_sapiensENSP0000036810010099.8476pan_troglodytesENSPTRP0000006379910099.8476
ENSG00000113522homo_sapiensENSP0000036810010099.8476gorilla_gorillaENSGGOP0000000103910099.8476
ENSG00000113522homo_sapiensENSP0000036810093.7585.1372ornithorhynchus_anatinusENSOANP0000001275291.517983.1101
ENSG00000113522homo_sapiensENSP0000036810093.826287.6524sarcophilus_harrisiiENSSHAP0000001261293.826287.6524
ENSG00000113522homo_sapiensENSP0000036810071.646366.3872notamacropus_eugeniiENSMEUP0000000451971.70166.4378
ENSG00000113522homo_sapiensENSP0000036810088.338486.0518choloepus_hoffmanniENSCHOP0000000508991.259888.8976
ENSG00000113522homo_sapiensENSP0000036810097.103794.2835dasypus_novemcinctusENSDNOP0000000211796.369193.5704
ENSG00000113522homo_sapiensENSP0000036810077.286674.7713erinaceus_europaeusENSEEUP0000000063577.345574.8284
ENSG00000113522homo_sapiensENSP0000036810078.201274.4665echinops_telfairiENSETEP0000000694478.560574.8086
ENSG00000113522homo_sapiensENSP0000036810099.618998.6281callithrix_jacchusENSCJAP0000004853499.618998.6281
ENSG00000113522homo_sapiensENSP0000036810090.472689.7104cercocebus_atysENSCATP0000003633499.580598.7416
ENSG00000113522homo_sapiensENSP0000036810097.027495.4268macaca_mulattaENSMMUP0000004935390.219788.7314
ENSG00000113522homo_sapiensENSP0000036810099.618998.9329macaca_nemestrinaENSMNEP0000002408996.457695.7934
ENSG00000113522homo_sapiensENSP0000036810099.771399.2378papio_anubisENSPANP0000000351999.847499.3135
ENSG00000113522homo_sapiensENSP0000036810099.847699.2378mandrillus_leucophaeusENSMLEP0000003924199.847699.2378
ENSG00000113522homo_sapiensENSP0000036810092.225689.5579tursiops_truncatusENSTTRP0000000243795.501292.7388
ENSG00000113522homo_sapiensENSP0000036810098.399496.189vulpes_vulpesENSVVUP0000003403998.399496.189
ENSG00000113522homo_sapiensENSP0000036810097.484892.3018mus_spretusMGP_SPRETEiJ_P002802097.484892.3018
ENSG00000113522homo_sapiensENSP0000036810098.246995.8079equus_asinusENSEASP0000502615898.246995.8079
ENSG00000113522homo_sapiensENSP0000036810097.637294.8171capra_hircusENSCHIP0000000315496.171293.3934
ENSG00000113522homo_sapiensENSP0000036810098.018395.3506loxodonta_africanaENSLAFP0000000818998.018395.3506
ENSG00000113522homo_sapiensENSP0000036810016.387215.0152panthera_leoENSPLOP0000000233284.645777.5591
ENSG00000113522homo_sapiensENSP0000036810096.417793.9787ailuropoda_melanoleucaENSAMEP0000003931293.912491.5368
ENSG00000113522homo_sapiensENSP0000036810054.725652.2866bos_indicus_hybridENSBIXP0000504216296.896192.5776
ENSG00000113522homo_sapiensENSP0000036810098.018395.0457bos_indicus_hybridENSBIXP0000501384798.018395.0457
ENSG00000113522homo_sapiensENSP0000036810095.274492.6829oryctolagus_cuniculusENSOCUP0000001621598.502895.8235
ENSG00000113522homo_sapiensENSP0000036810098.246995.5031equus_caballusENSECAP0000000920498.246995.5031
ENSG00000113522homo_sapiensENSP0000036810098.399496.189canis_lupus_familiarisENSCAFP0084501485698.399496.189
ENSG00000113522homo_sapiensENSP0000036810098.246996.2652panthera_pardusENSPPRP0000001582898.246996.2652
ENSG00000113522homo_sapiensENSP0000036810098.932996.5701marmota_marmota_marmotaENSMMMP0000001790398.857696.4966
ENSG00000113522homo_sapiensENSP0000036810098.704396.3415balaenoptera_musculusENSBMSP0001002378098.704396.3415
ENSG00000113522homo_sapiensENSP0000036810094.131190.0915cavia_porcellusENSCPOP0000000201996.862792.7059
ENSG00000113522homo_sapiensENSP0000036810098.323296.1128felis_catusENSFCAP0000001613198.398296.1861
ENSG00000113522homo_sapiensENSP0000036810060.975658.9177ursus_americanusENSUAMP0000000645293.567390.4094
ENSG00000113522homo_sapiensENSP0000036810037.576236.2805ursus_americanusENSUAMP0000001960294.807791.5385
ENSG00000113522homo_sapiensENSP0000036810093.673887.5762monodelphis_domesticaENSMODP0000001744392.40686.391
ENSG00000113522homo_sapiensENSP0000036810095.731792.7591bison_bison_bisonENSBBBP0000002866895.731792.7591
ENSG00000113522homo_sapiensENSP0000036810096.493993.4451monodon_monocerosENSMMNP0001500136294.196491.2202
ENSG00000113522homo_sapiensENSP0000036810096.036691.9207sus_scrofaENSSSCP0000005805392.783588.8071
ENSG00000113522homo_sapiensENSP0000036810098.704396.6463microcebus_murinusENSMICP0000001133598.704396.6463
ENSG00000113522homo_sapiensENSP0000036810085.975680.564octodon_degusENSODEP0000001003490.748285.0362
ENSG00000113522homo_sapiensENSP0000036810045.884144.2835jaculus_jaculusENSJJAP0000000407498.045694.6254
ENSG00000113522homo_sapiensENSP0000036810097.865995.1982ovis_aries_rambouilletENSOARP0002000019697.865995.1982
ENSG00000113522homo_sapiensENSP0000036810096.417793.8262ursus_maritimusENSUMAP0000002508787.543385.1903
ENSG00000113522homo_sapiensENSP0000036810086.81484.2226ochotona_princepsENSOPRP0000001071586.81484.2226
ENSG00000113522homo_sapiensENSP0000036810096.570193.3689delphinapterus_leucasENSDLEP0000000305894.270891.1458
ENSG00000113522homo_sapiensENSP0000036810098.399496.1128physeter_catodonENSPCTP0000500849698.399496.1128
ENSG00000113522homo_sapiensENSP0000036810097.408592.2256mus_caroliMGP_CAROLIEiJ_P002664597.408592.2256
ENSG00000113522homo_sapiensENSP0000036810097.484892.3018mus_musculusENSMUSP0000002064997.484892.3018
ENSG00000113522homo_sapiensENSP000003681009.222568.91768dipodomys_ordiiENSDORP0000002142899.180395.9016
ENSG00000113522homo_sapiensENSP0000036810098.399495.2744mustela_putorius_furoENSMPUP0000001043898.399495.2744
ENSG00000113522homo_sapiensENSP0000036810099.237897.9421aotus_nancymaaeENSANAP0000000170099.237897.9421
ENSG00000113522homo_sapiensENSP0000036810099.542798.1707saimiri_boliviensis_boliviensisENSSBOP0000003768999.542798.1707
ENSG00000113522homo_sapiensENSP0000036810094.43691.9969vicugna_pacosENSVPAP0000000356897.712995.1893
ENSG00000113522homo_sapiensENSP0000036810099.923899.2378chlorocebus_sabaeusENSCSAP0000000994699.923899.2378
ENSG00000113522homo_sapiensENSP0000036810056.478754.8018tupaia_belangeriENSTBEP0000000684670.437368.346
ENSG00000113522homo_sapiensENSP0000036810097.332392.5305mesocricetus_auratusENSMAUP0000000956397.332392.5305
ENSG00000113522homo_sapiensENSP0000036810098.399495.9604phocoena_sinusENSPSNP0000000126698.399495.9604
ENSG00000113522homo_sapiensENSP0000036810097.942195.4268camelus_dromedariusENSCDRP0000500527497.942195.4268
ENSG00000113522homo_sapiensENSP0000036810097.713493.5976carlito_syrichtaENSTSYP0000000701597.713493.5976
ENSG00000113522homo_sapiensENSP0000036810098.246996.2652panthera_tigris_altaicaENSPTIP0000001906498.246996.2652
ENSG00000113522homo_sapiensENSP0000036810097.408592.3018rattus_norvegicusENSRNOP0000006237897.408592.3018
ENSG00000113522homo_sapiensENSP0000036810098.628196.5701prolemur_simusENSPSMP0000003353498.628196.5701
ENSG00000113522homo_sapiensENSP0000036810019.283518.5976microtus_ochrogasterENSMOCP0000002135298.828195.3125
ENSG00000113522homo_sapiensENSP0000036810079.573276.5244sorex_araneusENSSARP0000001066079.573276.5244
ENSG00000113522homo_sapiensENSP0000036810097.027491.9207peromyscus_maniculatus_bairdiiENSPEMP0000003655897.027491.9207
ENSG00000113522homo_sapiensENSP0000036810097.027494.0549bos_mutusENSBMUP0000001921697.101494.1266
ENSG00000113522homo_sapiensENSP0000036810097.408592.2256mus_spicilegusENSMSIP0000002078897.408592.2256
ENSG00000113522homo_sapiensENSP0000036810096.722692.3018cricetulus_griseus_chok1gshdENSCGRP0000100279496.870292.4427
ENSG00000113522homo_sapiensENSP0000036810085.137282.3933pteropus_vampyrusENSPVAP0000001430085.791183.0261
ENSG00000113522homo_sapiensENSP0000036810097.408594.7409myotis_lucifugusENSMLUP0000001509597.112594.4529
ENSG00000113522homo_sapiensENSP0000036810093.673887.5vombatus_ursinusENSVURP0001000754193.673887.5
ENSG00000113522homo_sapiensENSP0000036810097.713494.8933rhinolophus_ferrumequinumENSRFEP0001002577497.713494.8933
ENSG00000113522homo_sapiensENSP0000036810096.112892.3018neovison_visonENSNVIP0000002286696.039692.2315
ENSG00000113522homo_sapiensENSP0000036810098.018395.0457bos_taurusENSBTAP0000001494598.018395.0457
ENSG00000113522homo_sapiensENSP0000036810097.637293.75heterocephalus_glaber_femaleENSHGLP0000004049196.898693.0408
ENSG00000113522homo_sapiensENSP0000036810097.408596.6463rhinopithecus_bietiENSRBIP0000001904499.765898.9852
ENSG00000113522homo_sapiensENSP0000036810098.399496.189canis_lupus_dingoENSCAFP0002001784898.399496.189
ENSG00000113522homo_sapiensENSP0000036810098.628195.9604sciurus_vulgarisENSSVLP0000502807898.628195.9604
ENSG00000113522homo_sapiensENSP0000036810093.978787.3476phascolarctos_cinereusENSPCIP0000000052193.978787.3476
ENSG00000113522homo_sapiensENSP0000036810087.881184.6037procavia_capensisENSPCAP0000000200692.834189.372
ENSG00000113522homo_sapiensENSP0000036810019.43618.6738nannospalax_galiliENSNGAP0000000126697.328293.5115
ENSG00000113522homo_sapiensENSP000003681008.61288.00305nannospalax_galiliENSNGAP0000002675491.12984.6774
ENSG00000113522homo_sapiensENSP0000036810098.094595.0457bos_grunniensENSBGRP0000000473798.094595.0457
ENSG00000113522homo_sapiensENSP0000036810094.207390.1677chinchilla_lanigeraENSCLAP0000002118297.399593.223
ENSG00000113522homo_sapiensENSP0000036810097.942195.3506cervus_hanglu_yarkandensisENSCHYP0000000273297.942195.3506
ENSG00000113522homo_sapiensENSP0000036810098.399495.3506catagonus_wagneriENSCWAP0000000032998.399495.3506
ENSG00000113522homo_sapiensENSP0000036810098.704396.189ictidomys_tridecemlineatusENSSTOP0000000887098.704396.189
ENSG00000113522homo_sapiensENSP0000036810098.475696.4939otolemur_garnettiiENSOGAP0000001387998.550796.5675
ENSG00000113522homo_sapiensENSP0000036810099.542798.3232cebus_imitatorENSCCAP0000003919899.542798.3232
ENSG00000113522homo_sapiensENSP0000036810098.856796.2652urocitellus_parryiiENSUPAP0001002029798.856796.2652
ENSG00000113522homo_sapiensENSP0000036810093.06490.3201moschus_moschiferusENSMMSP0000000258897.836594.9519
ENSG00000113522homo_sapiensENSP0000036810099.923899.1616rhinopithecus_roxellanaENSRROP0000002933599.923899.1616
ENSG00000113522homo_sapiensENSP0000036810097.56192.2256mus_pahariMGP_PahariEiJ_P003341997.56192.2256
ENSG00000113522homo_sapiensENSP0000036810033.765232.0122propithecus_coquereliENSPCOP0000000397891.908787.1369
ENSG00000113522homo_sapiensENSP0000036810047.942124.6189caenorhabditis_elegansT04H1.4b.147.942124.6189
ENSG00000113522homo_sapiensENSP0000036810052.362828.2774drosophila_melanogasterFBpp029088252.124428.1487
ENSG00000113522homo_sapiensENSP0000036810020.884113.7957ciona_intestinalisENSCINP0000000324568.545.25
ENSG00000113522homo_sapiensENSP0000036810020.579310.2896ciona_intestinalisENSCINP0000000323556.603828.3019
ENSG00000113522homo_sapiensENSP0000036810010.67076.47866ciona_intestinalisENSCINP0000003132565.420639.7196
ENSG00000113522homo_sapiensENSP0000036810058.917741.8445petromyzon_marinusENSPMAP0000000460474.255552.7378
ENSG00000113522homo_sapiensENSP0000036810076.143355.9451eptatretus_burgeriENSEBUP0000002504175.681855.6061
ENSG00000113522homo_sapiensENSP0000036810087.576270.9604callorhinchus_miliiENSCMIP0000004304887.576270.9604
ENSG00000113522homo_sapiensENSP0000036810075.228759.375latimeria_chalumnaeENSLACP0000000478182.732665.2976
ENSG00000113522homo_sapiensENSP0000036810087.347672.7896lepisosteus_oculatusENSLOCP0000001274387.347672.7896
ENSG00000113522homo_sapiensENSP0000036810083.765265.1677clupea_harengusENSCHAP0000000736583.637765.0685
ENSG00000113522homo_sapiensENSP0000036810086.204370.9604danio_rerioENSDARP0000012428486.204370.9604
ENSG00000113522homo_sapiensENSP0000036810085.823270.8841carassius_auratusENSCARP0000005313985.627470.7224
ENSG00000113522homo_sapiensENSP0000036810081.478765.2439carassius_auratusENSCARP0000007697082.42165.9985
ENSG00000113522homo_sapiensENSP000003681009.451228.07927carassius_auratusENSCARP0000005243979.487267.9487
ENSG00000113522homo_sapiensENSP0000036810011.05188.91768carassius_auratusENSCARP0000005239971.428657.6355
ENSG00000113522homo_sapiensENSP0000036810086.737870.4268astyanax_mexicanusENSAMXP0000002050486.671770.3732
ENSG00000113522homo_sapiensENSP0000036810084.908568.5976ictalurus_punctatusENSIPUP0000001867184.973368.6499
ENSG00000113522homo_sapiensENSP0000036810072.56156.4024esox_luciusENSELUP000000619108062.1849
ENSG00000113522homo_sapiensENSP0000036810028.429923.1707electrophorus_electricusENSEEEP0000000569979.530964.8188
ENSG00000113522homo_sapiensENSP0000036810055.868944.9695electrophorus_electricusENSEEEP0000001389462.06649.9577
ENSG00000113522homo_sapiensENSP0000036810085.442168.8262oncorhynchus_kisutchENSOKIP0000511598985.31268.7215
ENSG00000113522homo_sapiensENSP0000036810086.966570.1982oncorhynchus_mykissENSOMYP0000003405486.900270.1447
ENSG00000113522homo_sapiensENSP0000036810086.737869.6646salmo_salarENSSSAP0000010192584.798868.1073
ENSG00000113522homo_sapiensENSP0000036810086.432969.5122salmo_truttaENSSTUP0000003133586.367169.4593
ENSG00000113522homo_sapiensENSP0000036810083.460465.7774gadus_morhuaENSGMOP0000001452883.460465.7774
ENSG00000113522homo_sapiensENSP0000036810084.832367.5305fundulus_heteroclitusENSFHEP0000000931584.832367.5305
ENSG00000113522homo_sapiensENSP0000036810084.603767.4543poecilia_reticulataENSPREP0000000882981.918865.3137
ENSG00000113522homo_sapiensENSP0000036810084.298867.1494xiphophorus_maculatusENSXMAP0000003953384.298867.1494
ENSG00000113522homo_sapiensENSP0000036810083.536665.7774oryzias_latipesENSORLP0000003786783.600365.8276
ENSG00000113522homo_sapiensENSP0000036810083.536666.8445cyclopterus_lumpusENSCLMP0000502482883.536666.8445
ENSG00000113522homo_sapiensENSP0000036810069.817150.7622oreochromis_niloticusENSONIP0000006607171.843152.2353
ENSG00000113522homo_sapiensENSP0000036810084.37567.5305oreochromis_niloticusENSONIP0000006660776.134860.9354
ENSG00000113522homo_sapiensENSP0000036810070.960451.6006oreochromis_niloticusENSONIP0000000457473.888953.7302
ENSG00000113522homo_sapiensENSP000003681006.402444.57317haplochromis_burtoniENSHBUP0000000914391.304365.2174
ENSG00000113522homo_sapiensENSP0000036810084.37567.7591haplochromis_burtoniENSHBUP0000002275184.37567.7591
ENSG00000113522homo_sapiensENSP0000036810016.158513.4909haplochromis_burtoniENSHBUP0000000912380.30367.0455
ENSG00000113522homo_sapiensENSP000003681006.173784.87805astatotilapia_callipteraENSACLP0000002503469.827655.1724
ENSG00000113522homo_sapiensENSP0000036810058.460442.1494astatotilapia_callipteraENSACLP0000001268671.415351.4898
ENSG00000113522homo_sapiensENSP0000036810084.451267.9116astatotilapia_callipteraENSACLP0000001546984.451267.9116
ENSG00000113522homo_sapiensENSP0000036810015.62512.4238astatotilapia_callipteraENSACLP0000002505080.392263.9216
ENSG00000113522homo_sapiensENSP0000036810084.756167.3018sparus_aurataENSSAUP0001002101284.756167.3018
ENSG00000113522homo_sapiensENSP0000036810084.984867.9116lates_calcariferENSLCAP0001004321584.9267.8599
ENSG00000113522homo_sapiensENSP0000036810089.024476.3719xenopus_tropicalisENSXETP0000008422787.359874.9439
ENSG00000113522homo_sapiensENSP0000036810092.682981.6311chrysemys_picta_belliiENSCPBP0000002306892.682981.6311
ENSG00000113522homo_sapiensENSP0000036810086.890276.2195sphenodon_punctatusENSSPUP0000001315491.127179.9361
ENSG00000113522homo_sapiensENSP0000036810086.356776.6768crocodylus_porosusENSCPRP0000501318886.290976.6184
ENSG00000113522homo_sapiensENSP0000036810028.201224.0091laticauda_laticaudataENSLLTP0000000863386.046573.2558
ENSG00000113522homo_sapiensENSP0000036810056.554947.7134laticauda_laticaudataENSLLTP0000000965687.089273.4742
ENSG00000113522homo_sapiensENSP0000036810090.091578.125notechis_scutatusENSNSUP0000000795590.091578.125
ENSG00000113522homo_sapiensENSP0000036810079.649466.9969pseudonaja_textilisENSPTXP0000000484183.399870.1516
ENSG00000113522homo_sapiensENSP0000036810090.472677.5915anas_platyrhynchos_platyrhynchosENSAPLP0000002688190.472677.5915
ENSG00000113522homo_sapiensENSP0000036810090.243977.1341gallus_gallusENSGALP0001002263590.175277.0754
ENSG00000113522homo_sapiensENSP0000036810090.777477.5915meleagris_gallopavoENSMGAP0000000926690.708377.5324
ENSG00000113522homo_sapiensENSP0000036810089.253176.6768serinus_canariaENSSCAP0000001462589.253176.6768
ENSG00000113522homo_sapiensENSP0000036810089.253176.9817parus_majorENSPMJP0000001927789.253176.9817
ENSG00000113522homo_sapiensENSP0000036810090.243978.811anolis_carolinensisENSACAP0000001252890.243978.811
ENSG00000113522homo_sapiensENSP000003681006.859765.41159neolamprologus_brichardiENSNBRP0000002717788.235369.6078
ENSG00000113522homo_sapiensENSP0000036810015.701212.5762neolamprologus_brichardiENSNBRP0000002715980.784364.7059
ENSG00000113522homo_sapiensENSP0000036810084.832367.9116neolamprologus_brichardiENSNBRP0000000720284.832367.9116
ENSG00000113522homo_sapiensENSP0000036810037.347631.7073naja_najaENSNNAP0000001947487.656574.4186
ENSG00000113522homo_sapiensENSP0000036810090.243977.6677podarcis_muralisENSPMRP0000001749590.243977.6677
ENSG00000113522homo_sapiensENSP0000036810089.557976.5244geospiza_fortisENSGFOP0000000186289.557976.5244
ENSG00000113522homo_sapiensENSP0000036810089.557976.2957taeniopygia_guttataENSTGUP0000003853489.557976.2957
ENSG00000113522homo_sapiensENSP0000036810086.737872.561erpetoichthys_calabaricusENSECRP0000001256286.80472.6163
ENSG00000113522homo_sapiensENSP0000036810084.679966.9207kryptolebias_marmoratusENSKMAP0000001291984.679966.9207
ENSG00000113522homo_sapiensENSP0000036810090.320177.5152salvator_merianaeENSSMRP0000002310190.320177.5152
ENSG00000113522homo_sapiensENSP0000036810082.774464.4055oryzias_javanicusENSOJAP0000002358782.460164.161
ENSG00000113522homo_sapiensENSP0000036810016.692113.4146amphilophus_citrinellusENSACIP0000000047081.412665.4275
ENSG00000113522homo_sapiensENSP0000036810010.89948.6128amphilophus_citrinellusENSACIP0000000049177.717461.413
ENSG00000113522homo_sapiensENSP0000036810081.631165.0915amphilophus_citrinellusENSACIP0000001823484.798167.6168
ENSG00000113522homo_sapiensENSP0000036810084.451268.064dicentrarchus_labraxENSDLAP0000501362484.386968.0122
ENSG00000113522homo_sapiensENSP0000036810083.841567.2256amphiprion_perculaENSAPEP0000002474185.271368.3721
ENSG00000113522homo_sapiensENSP000003681003.201222.89634oryzias_sinensisENSOSIP0000000429495.454586.3636
ENSG00000113522homo_sapiensENSP0000036810019.817115.8537oryzias_sinensisENSOSIP0000003541678.787963.0303
ENSG00000113522homo_sapiensENSP0000036810091.539679.5732pelodiscus_sinensisENSPSIP0000001206792.101280.0613
ENSG00000113522homo_sapiensENSP0000036810088.033577.439gopherus_evgoodeiENSGEVP0000501351192.920481.7377
ENSG00000113522homo_sapiensENSP0000036810092.378181.4787chelonoidis_abingdoniiENSCABP0000001618092.378181.4787
ENSG00000113522homo_sapiensENSP0000036810084.908567.6067seriola_dumeriliENSSDUP0000002917484.908567.6067
ENSG00000113522homo_sapiensENSP0000036810080.716564.4055cottoperca_gobioENSCGOP0000001826183.715466.7984
ENSG00000113522homo_sapiensENSP0000036810091.844580.7165struthio_camelus_australisENSSCUP0000000307391.844580.7165
ENSG00000113522homo_sapiensENSP0000036810090.320177.5915anser_brachyrhynchusENSABRP0000001895690.320177.5915
ENSG00000113522homo_sapiensENSP0000036810079.954363.9482gasterosteus_aculeatusENSGACP0000002739279.954363.9482
ENSG00000113522homo_sapiensENSP0000036810082.469565.5488cynoglossus_semilaevisENSCSEP0000002329882.031865.2009
ENSG00000113522homo_sapiensENSP0000036810084.679967.6067poecilia_formosaENSPFOP0000000342584.679967.6067
ENSG00000113522homo_sapiensENSP0000036810083.765266.6159myripristis_murdjanENSMMDP0000502587085.326167.8571
ENSG00000113522homo_sapiensENSP0000036810082.698266.311sander_luciopercaENSSLUP0000005777484.435867.7043
ENSG00000113522homo_sapiensENSP0000036810089.634176.6006strigops_habroptilaENSSHBP0000500642989.634176.6006
ENSG00000113522homo_sapiensENSP0000036810085.06168.2165amphiprion_ocellarisENSAOCP0000001217585.06168.2165
ENSG00000113522homo_sapiensENSP0000036810092.835481.7835terrapene_carolina_triunguisENSTMTP0000002163892.835481.7835
ENSG00000113522homo_sapiensENSP0000036810086.737869.9695hucho_huchoENSHHUP0000007013184.798868.4054
ENSG00000113522homo_sapiensENSP0000036810084.679966.5396betta_splendensENSBSLP0000000614981.391963.956
ENSG00000113522homo_sapiensENSP0000036810087.042770.4268pygocentrus_nattereriENSPNAP0000002044487.042770.4268
ENSG00000113522homo_sapiensENSP0000036810084.679967.4543anabas_testudineusENSATEP0000001477584.615467.4029
ENSG00000113522homo_sapiensENSP0000036810061.12836.4329ciona_savignyiENSCSAVP0000001742860.528336.0755
ENSG00000113522homo_sapiensENSP0000036810050.609827.439saccharomyces_cerevisiaeYNL250W50.609827.439
ENSG00000113522homo_sapiensENSP0000036810084.832367.5305seriola_lalandi_dorsalisENSSLDP0000000857184.832367.5305
ENSG00000113522homo_sapiensENSP0000036810082.393365.8537labrus_bergyltaENSLBEP0000003326684.1967.2897
ENSG00000113522homo_sapiensENSP0000036810015.62512.5pundamilia_nyerereiENSPNYP0000000683380.392264.3137
ENSG00000113522homo_sapiensENSP0000036810084.298867.7591pundamilia_nyerereiENSPNYP0000002042484.298867.7591
ENSG00000113522homo_sapiensENSP0000036810085.137267.1494mastacembelus_armatusENSMAMP0000003174685.137267.1494
ENSG00000113522homo_sapiensENSP0000036810084.37567.6829stegastes_partitusENSSPAP0000001578380.101364.2547
ENSG00000113522homo_sapiensENSP0000036810085.518368.9024oncorhynchus_tshawytschaENSOTSP0000510398185.388168.7976
ENSG00000113522homo_sapiensENSP0000036810085.518368.9024oncorhynchus_tshawytschaENSOTSP0000507612985.388168.7976
ENSG00000113522homo_sapiensENSP0000036810035.670729.9543acanthochromis_polyacanthusENSAPOP0000000862685.871672.1101
ENSG00000113522homo_sapiensENSP0000036810034.298826.9055acanthochromis_polyacanthusENSAPOP0000001145281.669764.0653
ENSG00000113522homo_sapiensENSP0000036810090.015277.8963aquila_chrysaetos_chrysaetosENSACCP0002001979190.015277.8963
ENSG00000113522homo_sapiensENSP0000036810055.335444.3598nothobranchius_furzeriENSNFUP0001501358881.756865.5405
ENSG00000113522homo_sapiensENSP0000036810080.945163.6433cyprinodon_variegatusENSCVAP0000002775583.359565.5416
ENSG00000113522homo_sapiensENSP0000036810085.975669.6646denticeps_clupeoidesENSDCDP0000006132385.975669.6646
ENSG00000113522homo_sapiensENSP0000036810084.832367.1494larimichthys_croceaENSLCRP0000502948684.832367.1494
ENSG00000113522homo_sapiensENSP0000036810083.384166.6159takifugu_rubripesENSTRUP0000000868783.384166.6159
ENSG00000113522homo_sapiensENSP0000036810088.567176.6006ficedula_albicollisENSFALP0000001404288.567176.6006
ENSG00000113522homo_sapiensENSP0000036810082.088465.9299hippocampus_comesENSHCOP0000001884483.813267.3152
ENSG00000113522homo_sapiensENSP0000036810083.765268.2165cyprinus_carpio_carpioENSCCRP0000008725183.957268.3728
ENSG00000113522homo_sapiensENSP0000036810083.841568.9024cyprinus_carpio_carpioENSCCRP0000004259085.669870.405
ENSG00000113522homo_sapiensENSP0000036810090.853777.8201coturnix_japonicaENSCJPP0000502700990.577577.5836
ENSG00000113522homo_sapiensENSP0000036810084.756167.6829poecilia_latipinnaENSPLAP0000002761784.756167.6829
ENSG00000113522homo_sapiensENSP0000036810085.975671.1128sinocyclocheilus_grahamiENSSGRP0000011072185.975671.1128
ENSG00000113522homo_sapiensENSP0000036810073.246958.2317sinocyclocheilus_grahamiENSSGRP0000008652181.578964.8557
ENSG00000113522homo_sapiensENSP0000036810084.451267.9878maylandia_zebraENSMZEP0000500325184.451267.9878
ENSG00000113522homo_sapiensENSP0000036810015.62512.5maylandia_zebraENSMZEP0000501904880.392264.3137
ENSG00000113522homo_sapiensENSP0000036810083.841566.9207tetraodon_nigroviridisENSTNIP0000002138383.841566.9207
ENSG00000113522homo_sapiensENSP0000036810087.347671.6463paramormyrops_kingsleyaeENSPKIP0000000961687.28171.5918
ENSG00000113522homo_sapiensENSP0000036810087.195171.4939scleropages_formosusENSSFOP0001500064687.128771.4395
ENSG00000113522homo_sapiensENSP0000036810085.289672.1037leptobrachium_leishanenseENSLLEP0000003433587.490273.964
ENSG00000113522homo_sapiensENSP0000036810012.728711.814leptobrachium_leishanenseENSLLEP0000001826590.760984.2391
ENSG00000113522homo_sapiensENSP0000036810084.603768.2165scophthalmus_maximusENSSMAP0000000683984.603768.2165
ENSG00000113522homo_sapiensENSP0000036810083.612865.2439oryzias_melastigmaENSOMEP0000000489383.676665.2937

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000014contributes_to single-stranded DNA endodeoxyribonuclease activity1IDAHomo_sapiens(9606)Function
GO:0000019involved_in regulation of mitotic recombination1IDAHomo_sapiens(9606)Process
GO:0000722involved_in telomere maintenance via recombination1IBAHomo_sapiens(9606)Process
GO:0000723involved_in telomere maintenance1TASHomo_sapiens(9606)Process
GO:0000729involved_in DNA double-strand break processing1NASHomo_sapiens(9606)Process
GO:0000781located_in chromosome, telomeric region3HDA,IDAHomo_sapiens(9606)Component
GO:0000794is_active_in condensed nuclear chromosome1IBAHomo_sapiens(9606)Component
GO:0003677enables DNA binding1IDAHomo_sapiens(9606)Function
GO:0003678contributes_to DNA helicase activity1IMPHomo_sapiens(9606)Function
GO:0003691enables double-stranded telomeric DNA binding1IBAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005524enables ATP binding1IEAHomo_sapiens(9606)Function
GO:0005634located_in nucleus1NASHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm1TASHomo_sapiens(9606)Component
GO:0006281involved_in DNA repair1IDAHomo_sapiens(9606)Process
GO:0006302involved_in double-strand break repair2IBA,IMPHomo_sapiens(9606)Process
GO:0006310involved_in DNA recombination1IDAHomo_sapiens(9606)Process
GO:0006974acts_upstream_of_or_within DNA damage response1IDAHomo_sapiens(9606)Process
GO:0007004involved_in telomere maintenance via telomerase2IBA,IDAHomo_sapiens(9606)Process
GO:0007131involved_in reciprocal meiotic recombination1TASHomo_sapiens(9606)Process
GO:0008408contributes_to 3-5 exonuclease activity1IDAHomo_sapiens(9606)Function
GO:0016020located_in membrane1HDAHomo_sapiens(9606)Component
GO:0016887enables ATP hydrolysis activity1IEAHomo_sapiens(9606)Function
GO:0030674enables protein-macromolecule adaptor activity1IDAHomo_sapiens(9606)Function
GO:0030870part_of Mre11 complex4IBA,IDA,IPI,TASHomo_sapiens(9606)Component
GO:0031860involved_in telomeric 3 overhang formation1IMPHomo_sapiens(9606)Process
GO:0031954involved_in positive regulation of protein autophosphorylation1IDAHomo_sapiens(9606)Process
GO:0032206involved_in positive regulation of telomere maintenance1IMPHomo_sapiens(9606)Process
GO:0032508involved_in DNA duplex unwinding2IBA,IMPHomo_sapiens(9606)Process
GO:0033674involved_in positive regulation of kinase activity1IDAHomo_sapiens(9606)Process
GO:0035825involved_in homologous recombination1NASHomo_sapiens(9606)Process
GO:0035861located_in site of double-strand break1IDAHomo_sapiens(9606)Component
GO:0042802enables identical protein binding1IPIHomo_sapiens(9606)Function
GO:0043047enables single-stranded telomeric DNA binding1IBAHomo_sapiens(9606)Function
GO:0044818involved_in mitotic G2/M transition checkpoint1NASHomo_sapiens(9606)Process
GO:0046872enables metal ion binding1IEAHomo_sapiens(9606)Function
GO:0051880enables G-quadruplex DNA binding1IBAHomo_sapiens(9606)Function
GO:0070192involved_in chromosome organization involved in meiotic cell cycle1IBAHomo_sapiens(9606)Process
GO:0070533part_of BRCA1-C complex1IPIHomo_sapiens(9606)Component
GO:0090305involved_in nucleic acid phosphodiester bond hydrolysis1IBAHomo_sapiens(9606)Process
GO:0098687located_in chromosomal region1NASHomo_sapiens(9606)Component
GO:0110025involved_in DNA strand resection involved in replication fork processing1NASHomo_sapiens(9606)Process
GO:1904354involved_in negative regulation of telomere capping1IDAHomo_sapiens(9606)Process

Expression