Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases Disease
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions Kinase
Localizations N.A.
BulkPerturb-seq

Description

Ensembl ID ENSG00000112079 Gene ID 11329 Accession 17847
Symbol STK38 Alias NDR;NDR1 Full Name serine/threonine kinase 38
Status Confidence Length 53588 bases Strand Minus strand
Position 6 : 36493892 - 36547479 RNA binding domain N.A.
Summary This gene encodes a member of the AGC serine/threonine kinase family of proteins. The kinase activity of this protein is regulated by autophosphorylation and phosphorylation by other upstream kinases. This protein has been shown to function in the cell cycle and apoptosis. This protein has also been found to regulate the protein stability and transcriptional activity of the MYC oncogene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
STK38-201 ENST00000229812 3585 465aa ENSP00000229812

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000287enables magnesium ion binding1IDAHomo_sapiens(9606)Function
GO:0004674enables protein serine/threonine kinase activity2IBA,IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005524enables ATP binding1IDAHomo_sapiens(9606)Function
GO:0005634located_in nucleus1IDAHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm1IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol1IDAHomo_sapiens(9606)Component
GO:0006468involved_in protein phosphorylation1IDAHomo_sapiens(9606)Process
GO:0018105involved_in peptidyl-serine phosphorylation1IBAHomo_sapiens(9606)Process
GO:0031435enables mitogen-activated protein kinase kinase kinase binding1IPIHomo_sapiens(9606)Function
GO:0035556involved_in intracellular signal transduction2IBA,IDAHomo_sapiens(9606)Process
GO:0036211involved_in protein modification process1IDAHomo_sapiens(9606)Process
GO:0043407involved_in negative regulation of MAP kinase activity1IDAHomo_sapiens(9606)Process
GO:0045296enables cadherin binding1HDAHomo_sapiens(9606)Function
GO:0098978located_in glutamatergic synapse1IEAHomo_sapiens(9606)Component
GO:0099173involved_in postsynapse organization1IEAHomo_sapiens(9606)Process
GO:0106310enables protein serine kinase activity1IEAHomo_sapiens(9606)Function

Expression